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42
result(s) for
"Reilly, J.J."
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Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic review
2011
Background and objective: The last systematic review on the health consequences of child and adolescent obesity found little evidence on consequences for adult health. The present study aimed to summarize evidence on the long-term impact of child and adolescent obesity for premature mortality and physical morbidity in adulthood. Methods: Systematic review with evidence searched from January 2002 to June 2010. Studies were included if they contained a measure of overweight and/or obesity between birth and 18 years (exposure measure) and premature mortality and physical morbidity (outcome) in adulthood. Results: Five eligible studies examined associations between overweight and/or obesity, and premature mortality: 4/5 found significantly increased risk of premature mortality with child and adolescent overweight or obesity. All 11 studies with cardiometabolic morbidity as outcomes reported that overweight and obesity were associated with significantly increased risk of later cardiometabolic morbidity (diabetes, hypertension, ischaemic heart disease, and stroke) in adult life, with hazard ratios ranging from 1.1-5.1. Nine studies examined associations of child or adolescent overweight and obesity with other adult morbidity: studies of cancer morbidity were inconsistent; child and adolescent overweight and obesity were associated with significantly increased risk of later disability pension, asthma, and polycystic ovary syndrome symptoms. Conclusions: A relatively large and fairly consistent body of evidence now demonstrates that overweight and obesity in childhood and adolescence have adverse consequences on premature mortality and physical morbidity in adulthood.
Journal Article
Obesity impairs academic attainment in adolescence: findings from ALSPAC, a UK cohort
2014
Objective:
While being overweight or obese in adolescence may have detrimental effects on academic attainment, the evidence base is limited by reliance on cross-sectional studies with small sample sizes, failure to take account of confounders and lack of consideration of potential mediators. The present study aimed to address these limitations and examine longitudinal associations between obesity in adolescence and academic attainment.
Design:
Associations between weight status at 11 years old and academic attainment assessed by national tests at 11, 13 and 16 years were examined in the Avon Longitudinal Study of Parents and Children. Healthy weight was defined as body mass index (BMI)
Z
-score <1.04; overweight as BMI
Z
-score 1.04–1.63; obesity as BMI
Z
-score ⩾1.64.
Participants:
Data from 5966 participants with objectively measured weight status were examined: 71.4% were healthy weight (1935 males; 2325 females), 13.3% overweight (372 males; 420 females) and 15.3% obese (448 males; 466 females).
Results:
Girls obese at 11 years had lower academic attainment at 11, 13 and 16 years compared with those of a healthy weight, even after controlling for a wide range of confounders. Associations between obesity and academic attainment were less clear in boys. The potential mediating effects of depressive symptoms, intelligence quotient (IQ) and age of menarche in girls were explored, but when confounders were included, there was no strong evidence for mediation.
Conclusions:
For girls, obesity in adolescence has a detrimental impact on academic attainment 5 years later. Mental health, IQ and age of menarche did not mediate this relationship, suggesting that further work is required to understand the underlying mechanisms. Parents, education and public health policy makers should consider the wide reaching detrimental impact of obesity on educational outcomes in this age group.
Journal Article
Can we modulate physical activity in children
2011
There is concern that interventions that use physical activity to prevent obesity in children might be undermined by an 'Activitystat', which exerts an effect to maintain a low set point for physical activity. The present critique summarises evidence from systematic reviews of interventions, from empirical tests of the Activitystat hypothesis, from studies on the heritability of physical activity in childhood and the physical activity of children of and adolescents across a wide range of physical and cultural environments. This body of evidence is inconsistent with the Activitystat hypothesis in its current form, and suggests that the emphasis on physical activity in obesity prevention interventions in children should be increased, not reduced.
Journal Article
Impact of methodological decisions on accelerometer outcome variables in young children
2011
Background: The impact of accelerometer-related methodological decisions relating to the assessment of physical activity and sedentary time has not been conclusively determined in young children. Objectives: To determine the effects of epoch and cutoff points on the assessment of physical activity and sedentary time and to determine the accelerometer wear time required to achieve reliable accelerometer data in children. Design: Children were recruited from centres at Ghent, Glasgow, Gothenburg and Zaragoza. Methods: Physical activity was assessed for 1 week in 86 children (41 girls, 45 boys; mean age 7±2 years) by uniaxial accelerometry. The epoch was set at 15 s and reintegrated to 30 and 60 s. Time spent sedentary and in moderate and vigorous physical activity (MVPA) was assessed using a range of cutoff points. Number of days required to achieve 80% reliability was predicted using the Spearman–Brown Prophecy formula. Results: The Reilly cutoff points (<1100 counts per min (CPM)) indicated less sedentary time per day when comparing 15 vs 30 s and 15 vs 60 s epochs: 570±91 vs 579±93 min and 570±91 vs 579±94 min, respectively; P<0.05. Pate cutoff points (>420 counts per 15 s) reported more MVPA time per day compared with Sirard (890 counts per 15 s) and Puyau cutoff points (>3200 counts per min) using 15 s epoch: 78 (4–197) min (median (range) vs 18 (1–80) min and 24 (1–100) min, respectively; P<0.001. Compliance with guidelines of at least 60 min MVPA was 84, 78 and 73% for Pate cutoff points using 15, 30 and 60 s epochs, respectively, but 0% for Sirard and Puyau cutoff points across epochs. The number of days required to achieve 80% reliability for CPM, sedentary and MVPA time was 7.4–8.5 days. Conclusion: Choice of epoch and cutoff point significantly influenced the classification of sedentary and MVPA time and observed compliance to the MVPA guidelines.
Journal Article
Validation of anthropometry and foot-to-foot bioelectrical resistance against a three-component model to assess total body fat in children: the IDEFICS study
by
Huybrechts, I
,
Westerterp, K
,
Vicente-Rodriguez, G
in
692/699/2743/393
,
692/700/1720
,
692/700/478
2013
Objective:
To compare different field methods for estimating body fat mass with a reference value derived by a three-component (3C) model in pre-school and school children across Europe.
Design:
Multicentre validation study.
Subjects:
Seventy-eight preschool/school children aged 4–10 years from four different European countries.
Methods:
A standard measurement protocol was carried out in all children by trained field workers. A 3C model was used as the reference method. The field methods included height and weight measurement, circumferences measured at four sites, skinfold measured at two–six sites and foot-to-foot bioelectrical resistance (BIA) via TANITA scales.
Results:
With the exception of height and neck circumference, all single measurements were able to explain at least 74% of the fat-mass variance in the sample. In combination, circumference models were superior to skinfold models and height–weight models. The best predictions were given by trunk models (combining skinfold and circumference measurements) that explained 91% of the observed fat-mass variance. The optimal data-driven model for our sample includes hip circumference, triceps skinfold and total body mass minus resistance index, and explains 94% of the fat-mass variance with 2.44 kg fat mass limits of agreement. In all investigated models, prediction errors were associated with fat mass, although to a lesser degree in the investigated skinfold models, arm models and the data-driven models.
Conclusion:
When studying total body fat in childhood populations, anthropometric measurements will give biased estimations as compared to gold standard measurements. Nevertheless, our study shows that when combining circumference and skinfold measurements, estimations of fat mass can be obtained with a limit of agreement of 1.91 kg in normal weight children and of 2.94 kg in overweight or obese children.
Journal Article
IDEFICS validation study on field methods for assessing physical activity and body composition in children: design and data collection
by
Huybrechts, I
,
Westerterp, K
,
Vicente-Rodríguez, G
in
631/443/319/1488/393
,
692/700/1720
,
692/700/478/174
2011
Objective: To describe the design, measurements and fieldwork of the IDEFICS (Identification and prevention of dietary- and lifestyle-induced health effects in children and infants) physical activity and body composition validation study, and to determine the potential and limitations of the data obtained. Design: Multicentre validation study. Subjects: A total of 98 children from four different European countries (age: 4–10 years). Methods: An 8-day measurement protocol was carried out in all children using a collaborative protocol. Reference methods were the doubly labelled water method for physical activity, and a three- and a four-compartment model for body composition. Investigated field methods were accelerometers, a physical activity questionnaire and various anthropometric measurements. Results: For the validation of physical activity field methods, it was possible to gather data from 83 to 89 children, laying the basis for age- and sex-specific results. The validation of body composition field methods is possible in 64–80 children and allows sex-specific analyses but has only limited statistical power in the youngest age group (<6 years). The amount of activity energy expenditure (AEE) varied between centres, sexes and age groups, with boys and older children having higher estimates of AEE. After normalisation of AEE by body weight, most group-specific differences diminished, except for country-specific differences. Conclusion: The IDEFICS validation study will allow age- and sex-specific investigation of questions pertaining to the validity of several field methods of body composition and physical activity, using established reference methods in four different European countries. From the participant analyses it can be concluded that the compliance for the investigated field methods was higher than that for the reference methods used in this validation study.
Journal Article
Growth reference charts for use in the United Kingdom
by
Booth, I W
,
Cole, T J
,
Preece, M A
in
Adolescent
,
Age Factors
,
Biological and medical sciences
2002
Since the introduction of new growth charts in the mid 1990s, there has been confusion about which charts should be used, with many districts using more than one version. Because of this uncertainty, an expert working party, the Growth Reference Review Group, was convened by the Royal College of Paediatrics and Child Health to provide guidance on the validity and comparability of the different charts currently in use. This paper describes the technical background to the construction and evaluation of growth charts and outlines the group's findings on the validity of each growth reference in relation to contemporary British children. The group concluded that for most clinical purposes the UK90 reference is superior and for many measures is the only usable reference that can be recommended, while the original Tanner–Whitehouse and the Gairdner–Pearson charts are no longer reliable for use at any age. After the age of 2 the revised Buckler–Tanner references are still suitable for assessing height. There are presently no reliable head circumference reference charts for use beyond infancy. The group propose that apart from refinements of chart design and layout, the new UK90 reference should now be “frozen”, with any future revisions only undertaken after careful planning and widespread consultation
Journal Article
Obesity in Iranian children
2002
We surveyed 4315 2–5 year olds in Iran. Prevalence of obesity (BMI >95th centile, Iranian reference data) was compared with the recent “IOTF” approach. Prevalence was significantly higher than expected, and increased with age, but contradictory trends were obtained from the two approaches. Monitoring of childhood obesity using the BMI in developing countries is indicated, but differences associated with obesity definition should be considered.
Journal Article