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Background Lymphoma with Mott cell change, or Mott cell lymphoma (MCL), is an uncommon variant of canine lymphoma. Because of its rare occurrence, there has been no comprehensive study describing the disease so far. Miniature dachshunds, a popular breed in Japan, sometimes experience MCL. Objectives To investigate the clinical characteristics and outcomes of MCL in miniature dachshunds. Methods Medical records were retrospectively reviewed to identify miniature dachshunds diagnosed with MCL and other types of lymphoma. Data on clinical and laboratory findings, treatments and outcomes were collected. Survival times were compared between miniature dachshunds with MCL and other types of lymphoma. Results Of the 87 miniature dachshunds diagnosed with lymphoma, 9 (10%) had cytological characteristics of MCL. All 9 miniature dachshunds with MCL were categorised as having alimentary lymphoma (small and/or large intestine, 6 dogs; mesenteric lymph node, 3 dogs). The median age was 3.1 years (range, 2.0–9.4 years). All nine dogs were treated with chemotherapeutic protocols used for large cell lymphoma or alkylating agents such as melphalan or chlorambucil. The overall response rate to initial chemotherapy was 78%, and the median progression‐free survival was 105 days. Overall survival in these nine dogs ranged from 6 to >1513 days (median, 240 days), which was significantly longer than in 29 miniature dachshunds with alimentary large cell lymphoma other than MCL (median, 57 days; p = 0.0491). Conclusions MCL in miniature dachshunds can be recognised as a peculiar type of B‐cell lymphoma occurring in relatively young dogs as an alimentary form and has a longer survival compared with typical alimentary large cell lymphoma. The present retrospective study described the clinical characteristics and outcomes of lymphoma with Mott cell change, or Mott cell lymphoma (MCL) in miniature dachshunds. The response rate to initial chemotherapy was 78%, and the median overall survival was 240 days, showing a better prognosis than that of large cell alimentary lymphoma in this study population. MCL in miniature dachshunds can be recognized as a peculiar type of lymphoma which appears to be prevalent in the breed.

Cover caption: The cover image is based on the Original Article Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds by Aki Ohmi et al., https://doi.org/10.1002/vms3.975.

Cover caption: The cover image is based on the Original Article Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds by Aki Ohmi et al., https://doi.org/10.1002/vms3.975.