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31 result(s) for "Robb, Don"
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Events call for reason, not anger
Tuesday demonstrated that the continental United States is vulnerable to attack. It is no longer prudent to sit securely in North America pulling political and military strings overseas. Canadians cannot escape the consequences of blunders by the U.S. We can only pray for peace, and wisdom from [Bush].
Hail to the chief : the American presidency
Primary text describes the powers and duties of the presidency while subtext highlights the accomplishments of individual presidents. Includes a timeline.
Why I'll give my vote to the Greens
The Green party is an attractive alternative to the others. They have a viable program and good candidates. The Greens are not yet bogged down in partisan pursuit of political power for the sake of the power. They act out of principle. They will have my vote.
Shouldn't teen centre be permanent part of Sault?
Truer words have never been written. A need for a permanent teen centre and increased prevention services for youth -- isn't it amazing that this is viewed as essential for our community? The teen centre board of directors and teen centre advisory board have been making every attempt to make our present site a permanent site. We ask the people of Sault Ste. Marie, is this offer fair? If the answer is yes, would they take the time to call trustees, administration and city councillors to let them know that now is the time to make the teen centre a permanent part of this extraordinary community?
Community support shows Teen Centre bid is acceptable
1. Since its exception on Dec. 27, 1997, the Teen Centre has paid 100 per cent of the utilities (gas, water and electricity) for the entire building, while leasing less than 30 per cent of the building. This has amounted to $73,678. The community needs to know that the success of our venture over the past two years is such that it is now impossible to reduce the level and scope of our operations. This facility is the ideal location for the Teen Centre. The board should understand this and do all it can to further the acquisition of the Collegiate facility for the Teen Centre and the teens of Sault Ste. Marie.
It takes time for teen centre to operate at full capacity
Mr. [Rob Odber] is correct in saying that the centre has maintained a low profile since opening in late December. As an organization we are striving to open a fine facility that truly meets the needs of the youth in this community. At the same time we need to make sure that our staff and volunteers are properly trained to run a successful facility that fulfills our mission statement of providing a safe and drug-free environment for the teens of this community.
Human embryonic stem cell–derived cardiomyocytes restore function in infarcted hearts of non-human primates
Cardiomyocyte transplantation after heart attack improves contractile function in monkeys. Pluripotent stem cell–derived cardiomyocyte grafts can remuscularize substantial amounts of infarcted myocardium and beat in synchrony with the heart, but in some settings cause ventricular arrhythmias. It is unknown whether human cardiomyocytes can restore cardiac function in a physiologically relevant large animal model. Here we show that transplantation of ∼750 million cryopreserved human embryonic stem cell–derived cardiomyocytes (hESC-CMs) enhances cardiac function in macaque monkeys with large myocardial infarctions. One month after hESC-CM transplantation, global left ventricular ejection fraction improved 10.6 ± 0.9% vs. 2.5 ± 0.8% in controls, and by 3 months there was an additional 12.4% improvement in treated vs. a 3.5% decline in controls. Grafts averaged 11.6% of infarct size, formed electromechanical junctions with the host heart, and by 3 months contained ∼99% ventricular myocytes. A subset of animals experienced graft-associated ventricular arrhythmias, shown by electrical mapping to originate from a point-source acting as an ectopic pacemaker. Our data demonstrate that remuscularization of the infarcted macaque heart with human myocardium provides durable improvement in left ventricular function.
Phylogeography of the second plague pandemic revealed through analysis of historical Yersinia pestis genomes
The second plague pandemic, caused by Yersinia pestis , devastated Europe and the nearby regions between the 14 th and 18 th centuries AD. Here we analyse human remains from ten European archaeological sites spanning this period and reconstruct 34 ancient Y. pestis genomes. Our data support an initial entry of the bacterium through eastern Europe, the absence of genetic diversity during the Black Death, and low within-outbreak diversity thereafter. Analysis of post-Black Death genomes shows the diversification of a Y. pestis lineage into multiple genetically distinct clades that may have given rise to more than one disease reservoir in, or close to, Europe. In addition, we show the loss of a genomic region that includes virulence-related genes in strains associated with late stages of the pandemic. The deletion was also identified in genomes connected with the first plague pandemic (541–750 AD), suggesting a comparable evolutionary trajectory of Y. pestis during both events. The second plague pandemic, caused by Yersinia pestis , started in the 14th century and recurred in Europe until the 18th century. Here, the authors reconstruct ancient Y. pestis genomes from human remains spanning this period, shedding light into the phylogeography and population structure of the European strains.