Explore the vast range of titles available.

Although direct ink writing (DIW) allows the rapid fabrication of unique 3D printed objects, the resins—or “inks”—available for this technique are in short supply and often offer little functionality, leading to the development of new, custom inks. However, when creating new inks, the ability of the ink to lead to a successful print, or the “printability,” must be considered. Thus, this work examined the effect of filler composition/concentration, printing parameters, and lattice structure on the printability of new polysiloxane inks incorporating high concentrations (50–70 wt%) of metallic and ceramic fillers as well as emulsions. Results suggest that strut diameter and spacing ratio have the most influence on the printability of DIW materials and that the printability of silica- and metal-filled inks is more predictable than ceramic-filled inks. Additionally, higher filler loadings and SC geometries led to stiffer printed parts than lower loadings and FCT geometries, and metal-filled inks were more thermally stable than ceramic-filled inks. The findings in this work provide important insights into the tradeoffs associated with the development of unique and/or multifunctional DIW inks, printability, and the final material’s performance.

Describes the Normative Treatment Planning program, an automated assessment tool that some case managers in IN's Area Agencies on Aging have begun to incorporate as part of their provision of community-based long-term-care services. The program provides guidelines & decision trees that enable case managers to assess needs & prescribe home-based long-term-care services. The program starts with a computerized version of the state's CHOICE & Medicaid Waiver program eligibility form, which includes state-related eligibility criteria for publicly funded long-term-care services. 2 Figures, 8 References. M. Maguire

Statistical projections for the Kirkland area show that there will be a 31-percent population increase by the year 2000. More important, from a real estate perspective, employment is projected to be up 67 percent in the next 13 years. Considering the number of new commercial developments proposed and under construction in Kirkland, coupled with these growth projections, it seems important to turn attention to this expanding industrial marketplace. Traditionally, the Kirkland market, an area that extends north from 124th Avenue East and west of Interstate 405, has been dominated by light industrial, combination space. (excerpt)

High-mountain ecosystems are experiencing the acute effects of climate change, most visibly through glacier recession and the greening of the terrestrial environment. The streams draining these landscapes are affected by these shifts, integrating hydrologic, geologic, and biological signals across the catchment. We examined the organic and inorganic carbon dynamics of streams in four Alpine catchments in Switzerland to assess how glacier loss and vegetation expansion are affecting the carbon cycle of these high-mountain ecosystems. We find that the organic carbon concentration and fluorescence properties associated with humic-like compounds increase with vegetation cover within a catchment, demonstrating the increasing importance of allochthonous dissolved organic carbon sources following glacier retreat. Meanwhile, streams transitioned from carbon dioxide sinks to sources with decreasing glacier coverage and increased vegetation coverage, with chemical weathering and soil respiration likely determining the balance. Periods of sink behavior were also observed in non-glaciated streams, possibly indicating that the chemical consumption of carbon dioxide could be more common in high-mountain, minimally vegetated catchments than previously known. Together, these results demonstrate the dramatic shifts in carbon dynamics of high-mountain streams following glacier recession, with significant changes to both the organic and inorganic carbon cycles. The clear link between the terrestrial and aquatic zones further emphasizes the coupled dynamics with which all hydrologic and biogeochemical changes in these ecosystems should be considered, including the carbon sink or source potential of montane ecosystems.

The shrinkage of glaciers and the vanishing of glacier-fed streams (GFSs) are emblematic of climate change. However, forecasts of how GFS microbiome structure and function will change under projected climate change scenarios are lacking. Combining 2,333 prokaryotic metagenome-assembled genomes with climatic, glaciological, and environmental data collected by the Vanishing Glaciers project from 164 GFSs draining Earth’s major mountain ranges, we here predict the future of the GFS microbiome until the end of the century under various climate change scenarios. Our model framework is rooted in a space-for-time substitution design and leverages statistical learning approaches. We predict that declining environmental selection promotes primary production in GFSs, stimulating both bacterial biomass and biodiversity. Concomitantly, predictions suggest that the phylogenetic structure of the GFS microbiome will change and entire bacterial clades are at risk. Furthermore, genomic projections reveal that microbiome functions will shift, with intensified solar energy acquisition pathways, heterotrophy and algal-bacterial interactions. Altogether, we project a ‘greener’ future of the world’s GFSs accompanied by a loss of clades that have adapted to environmental harshness, with consequences for ecosystem functioning. Little is known about how climate change impacts glacier-fed streams (GFSs) microbiomes. Here, using a modelling framework based on global GFS metagenomic, climatic and environmental data the authors predict future increases in GFS bacterial biomass and diversity, but potential loss of clades adapted to extreme conditions.

Hornworts comprise a bryophyte lineage that diverged from other extant land plants >400 million years ago and bears unique biological features, including a distinct sporophyte architecture, cyanobacterial symbiosis and a pyrenoid-based carbon-concentrating mechanism (CCM). Here, we provide three high-quality genomes of Anthoceros hornworts. Phylogenomic analyses place hornworts as a sister clade to liverworts plus mosses with high support. The Anthoceros genomes lack repeat-dense centromeres as well as whole-genome duplication, and contain a limited transcription factor repertoire. Several genes involved in angiosperm meristem and stomatal function are conserved in Anthoceros and upregulated during sporophyte development, suggesting possible homologies at the genetic level. We identified candidate genes involved in cyanobacterial symbiosis and found that LCIB , a Chlamydomonas CCM gene, is present in hornworts but absent in other plant lineages, implying a possible conserved role in CCM function. We anticipate that these hornwort genomes will serve as essential references for future hornwort research and comparative studies across land plants. Analyses of three high-quality genomes of Anthoceros hornworts place hornworts as a sister clade to the lineage including liverworts and mosses, and provide insights into the unique biological features of hornworts.

Three distinct MN1::BEND2 fusion‐positive tumors in pediatric patients. (A) Clinical course for each patient was variable in part due to differences in initial diagnosis. Each patient responded favorably to gross total resection and is stable at last follow‐up. (B) Histologic diversity, lack of prominent classical astroblastoma features, and variable immunoexpression of key markers makes microscopic diagnosis challenging.

Accounting for within-species variability in the relationship between occurrence and climate is essential to forecasting species’ responses to climate change. Few climate-vulnerability assessments explicitly consider intraspecific variation, and those that do typically assume that variability is best explained by genetic affinity. Here, we evaluate how well heterogeneity in responses to climate by a cold-adapted mammal, the American pika (Ochotona princeps), aligns with subdivisions of the geographic range by phylogenetic lineage, physiography, elevation or ecoregion. We find that variability in climate responses is most consistently explained by an ecoregional subdivision paired with background sites selected from a broad spatial extent indicative of long-term (millennial-scale) responses to climate. Our work challenges the common assumption that intraspecific variation in climate responses aligns with genetic affinity. Accounting for the appropriate context and scale of heterogeneity in species’ responses to climate will be critical for informing climate-adaptation management strategies at the local (spatial) extents at which such actions are typically implemented.

Three experiments were conducted to determine the effects of monensin supplementation during the stocker and finishing phase on feedlot performance and carcass characteristics of beef steers. In Exp. 1 and 2, steers (n = 61, BW = 345 ± 20 kg and n = 70, BW = 298 ± 26 kg) were fed hay and supplement or grazed wheat pasture (Exp. 1) or bermudagrass (Exp. 2) and then were transported 1,068 km to Canyon, TX, for finishing. For Exp. 3 steers (n = 59, BW = 322 ± 31 kg) grazed wheat pasture and then transported 636 km to Stillwater, OK, for finishing. Treatments were arranged as a 3 × 2 factorial with three monensin levels during the stocker phase (0, 800, 1600 g/ton fed in a free choice mineral) and two levels during finishing [0 (UN) or 37.5 mg/kg diet DM (RUM). There were no location × treatment interactions (P ≥ 0.19) for performance or carcass measurements, therefore data were pooled across locations. Stocker × feedlot treatment interactions were not observed for performance data (P ≥ 0.50), but were observed for carcass characteristics. Cattle consuming RUM in the feedlot had decreased (P < 0.01) DMI and increased (P < 0.01) G:F compared with UN. Cattle on 1600UN treatment had the greatest LM area whereas 0U had the least (103.4 vs 96.3 cm2). Steers on the 800UN and 1600UN treatments had decreased YG and 800RUM had the greatest (2.31 and 2.22 vs 2.75). Cattle consuming RUM during finishing had increased (P = 0.03) fat thickness compared to UN. Supplementation of monensin to stocker cattle may have minimal impact on subsequent feedlot performance. Providing monensin in feedlot diets still decreases DMI and improves feed efficiency of feedlot cattle.