Explore the vast range of titles available.

Hypernasality is a common characteristic of several speech disorders and can significantly affect perceived speech intelligibility and quality. Nasometry quantifies nasalance by calculating the proportion of acoustic energy emitted from the nasal cavity relative to the combined nasal and oral acoustic output during speech production and is commonly used in clinical assessment and research. However, commercially available nasometers are costly and limited in portability, restricting their use in resource-limited or remote settings. The primary purpose of this study was to design and build a low-cost, open-source mobile nasometer prototype (“mNasometer”) by leveraging advances in 3D printing, off-the-shelf electronic components, and a custom open-source mobile application. A secondary aim was to compare the electroacoustic and subjective performance of mNasometer with that of a gold-standard commercial nasometer. Electroacoustic analyses focused on comparing long-term averaged spectra and the oral/nasal acoustic isolation between the gold-standard commercial nasometer and the proposed mNasometer, which incorporates a 3D-printed nasal separation plate. In addition, nasalance scores were collected from ten healthy young adult participants using both systems during structured speech production tasks (i.e., reading standard passages or nasal sentences). Agreement between devices was evaluated using correlational analyses and comparative statistical procedures. Long-term averaged spectra exhibited similar profiles between the commercial nasometer and the mNasometer across different test stimuli, indicating comparable capture of stimulus energy distributions. Although the mNasometer demonstrated reduced oral–nasal acoustic isolation relative to the commercial system, objective nasalance scores followed similar overall trends between devices, with statistically significant stimulus-dependent differences observed. Frame-wise correlational analyses revealed significant correlations between nasalance measures obtained from the commercial nasometer and the mNasometer across most of the speech production tasks, suggesting that the reduced isolation did not critically compromise measurement correspondence. In summary, the low-cost, open-source mNasometer prototype provides nasalance measurements that show promising agreement with those of a gold-standard commercial device. Its reduced cost and increased portability suggest potential for expanded research and field-based applications in the objective assessment of nasalance.

What does more-than-human mean? How can we, as humans, understand that our ecology is only one of the many that do exist within the world? Furthermore, in which way should we step aside to let all ecological actors exercise their agency? And, more specifically, what should be the role of design and designers in tackling complex issues and in contributing to a major shift in thoughts? These questions fostered a reflection on the relation between possible futures and the design practice itself and set the basis for the creation of a provotype. A provotype (from “provocation” and “prototype”) is a conceptual product or an artifact whose objective is to foster reflections and provoke discussions mainly concerning social and environmental sustainability, innovations, and technologies, leaving gaps to be filled with the audience imagination.The research reported in this contribution deals with issues and questions that fall under the umbrella of the topic of alternative biopolitics in future scenarios: how can we co-design with more-than-human actors? In which way can symbiosis between different entities be achieved? What is the meaning of interspecies justice, and which should be the steps to follow to fulfill it? And, finally, maybe the most significant question to focus on: how can communication between different entities be fostered? The designed provotype consists of a fictional event (“The first Multispecies Symposium”) which takes place in 2100, further helped the researchers in opening new reflections that made it possible to experiment with participatory design and to finalize a tool that can be used to share and expand reflections about futures without hierarchies, not human-centered, sustainable progress and hope, participative futures.

Stained glass has played important roles in heritage building construction, however, conventional fabrication techniques have become economically prohibitive due to both capital costs and energy inefficiency, as well as high-level artistic and craft skills. To overcome these challenges, this study provides a new design methodology for customized 3D-printed polycarbonate (PC)-based stained-glass window alternatives using a fully open-source toolchain and methodology based on digital fabrication and hybrid crafts. Based on design thinking and open design principles, this procedure involves fabricating an additional insert made of (i) a PC substrate and (ii) custom geometries directly 3D printed on the substrate with PC-based 3D printing feedstock (iii) to be painted after the 3D printing process. This alternative is intended for customizable stained-glass design patterns to be used instead of traditional stained glass or in addition to conventional windows, making stained glass accessible and customizable according to users’ needs. Three approaches are developed and demonstrated to generate customized painted stained-glass geometries according to the different users’ skills and needs using (i) online-retrieved 3D and 2D patterns; (ii) custom patterns, i.e., hand-drawn and digital-drawn images; and (iii) AI-generated patterns. The proposed methodology shows potential for distributed applications in the building and heritage sectors, demonstrating its practical feasibility. Its use makes stained-glass-based products accessible to a broader range of end-users, especially for repairing and replicating existing conventional stained glass and designing new customizable products. The developed custom patterns are 50 times less expensive than traditional stained glass and can potentially improve thermal insulation, paving the way to energy efficiency and economic savings.

This work explores the use of additive manufacturing (AM) to reprocess recycled glass and carbon fibers in the automotive sector. It aims to foster exploitation of recycled Glass Fiber Reinforced Polymers (rGFRPs) and recycled Carbon Fiber Reinforced Polymers (rCFRPs) through two manufacturing workflows: indirect Fused Filament Fabrication (FFF) and UV-assisted Direct Ink Writing (UV-DIW). An industrial case study on vehicle components has been considered by prototyping one real component. After the tensile tests, some molds were fabricated with a FFF 3D printer for the indirect 3D printing process to cast an epoxy-based thermosetting resin with rGFs and rCFs. The second technology consisted in fabricating the parts by hardening in-situ a photo- and thermal-curable thermosetting acrylic liquid resin with rGFs. These results validate the use of AM and recycled composites for applications in the automotive sector. These approaches may be implemented for customizable components for batches below 100 vehicles as the first step for their exploitation.

Fused filament fabrication allows the direct manufacturing of customized and complex products although the layer-by-layer appearance of this process strongly affects the surface quality of the final parts. In recent years, an increasing number of post-processing treatments has been developed for the most used materials. Contrarily to other additive manufacturing technologies, metallization is not a common surface treatment for this process despite the increasing range of high-performing 3D printable materials. The objective of this work is to explore the use of physical vapor deposition sputtering for the chromium metallization of thermoplastic polymers and composites obtained by fused filament fabrication. The thermal and mechanical properties of five materials were firstly evaluated by means of differential scanning calorimetry and tensile tests. Meanwhile, a specific finishing torture test sample was designed and 3D printed to perform the metallization process and evaluate the finishing on different geometrical features. Furthermore, the roughness of the samples was measured before and after the metallization, and a cost analysis was performed to assess the cost-efficiency. To sum up, the metallization of five samples made with different materials was successfully achieved. Although some 3D printing defects worsened after the post-processing treatment, good homogeneity on the finest details was reached. These promising results may encourage further experimentations as well as the development of new applications, i.e., for the automotive and furniture fields.

Literature on the efficacy and safety of gender-affirming hormonal treatment (GAHT) in transgender people is limited. For this reason, in 2010 the European Network for the Investigation of Gender Incongruence (ENIGI) study was born. The aim of this review is to summarize evidence emerging from this prospective multicentric study and to identify future perspectives. GAHT was effective in inducing desired body changes in both trans AMAB and AFAB people (assigned male and female at birth, respectively). Evidence from the ENIGI study confirmed the overall safety of GAHT in the short/mid-term. In trans AMAB people, an increase in prolactin levels was demonstrated, whereas the most common side effects in trans AFAB people were acne development, erythrocytosis, and unfavorable changes in lipid profile. The main future perspectives should include the evaluation of the efficacy and safety of non-standardized hormonal treatment in non-binary trans people. Furthermore, long-term safety data on mortality rates, oncological risk, and cardiovascular, cerebrovascular and thromboembolic events are lacking. With this aim, we decided to extend the observation of the ENIGI study to 10 years in order to study all these aspects in depth and to answer these questions.

The amount of non-revenue water, mostly due to leakage, is around 126 billion cubic meters annually worldwide. A more efficient wastewater management strategy would use a parametric design for on-demand, customized pipe fittings, following the principles of distributed manufacturing. To fulfill this need, this study introduces an open-source parametric design of a 3D-printable easy-connect pipe fitting that offers compatibility with different dimensions and materials of pipes available on the market. Custom pipe fittings were 3D printed using a RepRap-class fused filament 3D printer, with polylactic acid (PLA), polyethylene terephthalate glycol (PETG), acrylonitrile styrene acrylate (ASA), and thermoplastic elastomer (TPE) as filament feedstocks for validation. The 3D-printed connectors underwent hydrostatic water pressure tests to ensure that they met the standards for residential, agricultural, and renewable energy production applications. All the printed parts passed numerous hydrostatic pressure tests. PETG couplings can tolerate up to 4.551 ± 0.138 MPa of hydrostatic pressure, which is eight times greater than the highest standard water pressure in the residential sector. Based on the economic analysis, the cost of 3D printing a pipe coupling is from three to seventeen times lower than purchasing a commercially available pipe fitting of a similar size. The new open-source couplings demonstrate particular potential for use in developing countries and remote areas.

Additive Manufacturing has significantly impacted circular design, expanding the opportunities for designing new artifacts following circular economy principles, e.g., using secondary raw materials. Small-format 3D printing has reached a broader audience of stakeholders, including end-users, when dealing with filament feedstocks from plastic and biomass waste. However, using large-format extrusion-based additive manufacturing with recycled feedstocks remains challenging, resulting in limited applications and awareness among practitioners. This work analyzes the most relevant product applications using large-format material extrusion additive manufacturing with recycled plastics and biomass waste feedstocks. It reviews the case studies from 2010 to mid-2024 dealing with new materials and applications from academic research and practical contexts. The applications were analyzed to outline the current situation and trends for large-format 3D printing with recycled plastics- and biomass-based feedstocks, focusing on secondary raw materials, manufacturability, impact on product aesthetics, application fields, and products. Despite more consolidated sectors, new technical applications using granulate feedstock systems, e.g., transportation, are emerging. Academic research studies new secondary raw materials and distributed practices through large-format 3D printing. Practitioners are exploiting different approaches to design products, optimizing building times, costs, and material usage through different manufacturing strategies, strengthening the product identity by highlighting circularity. Spreading specific expertise could enlarge the range of application sectors and products, as well as foster real-world collaborations and scaling-up. Thanks to this work, new synergies between the research and practical contexts can be encouraged for new circular economy practices, detecting and exploring new scraps, material categories, or Additive Manufacturing processes in the future.

The transition toward circular economy models has been progressively promoted in the last few years. Different disciplines and strategies may significantly support this change. Although the specific contribution derived from design, material science, and additive manufacturing is well-established, their interdisciplinary relationship in circular economy contexts is relatively unexplored. This paper aims to review the main case studies related to new circular economy models for waste valorization through extrusion-based additive manufacturing, circular materials, and new design strategies. The general patterns were investigated through a comprehensive analysis of 74 case studies from academic research and design practice in the last six-year period (2015–2021), focusing on the application fields, the 3D printing technologies, and the materials. Further considerations and future trends were then included by looking at the relevant funded projects and case studies of 2021. A broader number of applications, circular materials, and technologies were explored by the academic context, concerning the practice-based scenario linked to more consolidated fields. Thanks to the development of new strategies and experiential tools, academic research and practice can be linked to foster new opportunities to implement circular economy models.

As an abundant commodity, coffee production generates significant scraps and by-products, increasing the potential pollution hazards. Circular economy and bioeconomy can help valorize Spent Coffee Grounds (SCGs), e.g., as fillers in polymer-based composites using conventional manufacturing, i.e., injection molding. Large-format additive manufacturing with pellet extruders offers a further option for new applications, reducing costs for the valorization of biomass waste. However, its use in this context remains unexplored, especially for applications with complex geometries or critical overhangs. This work investigates new biomass waste-based materials for large-format additive manufacturing with direct feeding extrusion, fabricating self-supported complex overhang geometries through nonplanar slicing. The thermal, rheological, and mechanical properties of three novel polymer-based pellet compounds with post-industrial SCGs, i.e., injection molding grade polylactic acid/SCGs, recycled low-density polyethylene/SCGs, and high-density polyethylene/SCGs, were herein investigated to evaluate their printability, defining their extrusion temperatures (190 °C and 170 °C). Results showed suitable viscosity ranges (133.6–839.7 Pa∙s) and accurate tensile values comparable with literature, e.g., ~ 1–3% minimum relative standard deviations (polylactic acid/SCGs), or conventional manufacturing, e.g., elastic moduli of 107.4 MPa (recycled low-density polyethylene/SCGs) and 587 MPa (high-density polyethylene/SCGs). Their use with large-format 3D printers was assessed thanks to nonplanar samples with complex overhang geometries, reaching a maximum curvature angle of 32° and fabricating overhangs up to 25° without supports. According to the tests, especially polylactic acid/SCGs, a bio-based compound, and recycled low-density polyethylene/SCGs, a fully recycled material, can be used for large-format 3D printing applications with complex geometries, e.g., furniture, interior, and exhibition design. This work paves the way for new materials for large-format additive manufacturing, reducing the need for 3D printing grade feedstock, cutting costs and consumption from filament processing, and fostering material waste reduction practices.