Explore the vast range of titles available.

BackgroundChild undernutrition remains a leading contributor to mortality, morbidity and impaired development in low-income and middle-income countries, particularly in India where rates of stunting and underweight persist despite broad policy and programme investments. The critical window for intervention is the first 1000 days, from conception to age 2, when both maternal and child factors influence lifelong outcomes.ObjectivesTo map the review level evidence on interventions to prevent and reduce child and maternal malnutrition across health, education, environment and engineering sectors in India, and assess the degree of alignment with current policy strategies targeting the first 1000 days.Eligibility criteriaIncluded sources were systematic reviews, meta-analyses and WHO guidelines published in English, addressing interventions for pregnant women, mothers of infants and children under 5 in India or other low-income/middle-income country settings.Sources of evidenceEvidence was identified via searches of MEDLINE, Cochrane Library, CINAHL, ERIC, GEOBASE, Engineering Village, and relevant policy reports and guidelines, up to July 2025.Charting methodsReviews were screened, and data were extracted on intervention design, implementation context, sectoral focus, population, outcomes, strength of evidence and evidence gaps.ResultsA total of 155 reviews met eligibility. Multisectoral approaches integrating nutrition, Water, Sanitation and Hygiene(WASH), education and social support showed the strongest impact for preventing stunting and improving child growth, particularly when targeted early. Intervention coverage and effectiveness were limited by gaps in cross-sector coordination, infrastructural constraints, poor supervision and exclusion of the youngest and poorest populations. Prevention in the first 1000 days yielded greatest benefits, but implementation challenges persist.ConclusionsIndia’s efforts against childhood malnutrition require integrated, context-specific and prevention-focused strategies. Mapping review evidence to policy reveals strengths and gaps, with lessons relevant for improving child and maternal nutrition in other high-burden regions.

ObjectiveThis interdisciplinary qualitative study aims to explore the health, education, engineering and environment factors impacting on feeding practices in rural India. The ultimate goal of the Participatory Approach for Nutrition in Children: Strengthening Health Education Engineering and Environment Linkages project is to identify challenges and opportunities for improvement to subsequently develop socioculturally appropriate, tailored, innovative interventions for the successful implementation of appropriate infant and young child feeding (IYCF) practices locally.DesignQualitative research method, involving five phases: (1) identification of local feeding practices; (2) identification of the local needs and opportunities for children aged 6–24 months; and (3–5) analysis of the gathered qualitative data, intervention design, review and distribution.SettingNine villages in two community development blocks, that is, Ghatol and Kushalgarh, located in the Banswara district in Rajasthan, India.Participants68 participants completed semistructured interviews or focus group discussions including: mothers, grandmothers, auxiliary nurse midwife, Anganwadi worker, ASHA Sahyogini, school teachers and local elected representative.Phenomenon of interestIYCF practices and the factors associated with it.AnalysisThematic analysis.ResultsOur results could be broadly categorised into two domains: (1) the current practices of IYCF and (2) the key drivers and challenges of IYCF. We explicate the complex phenomena and emergent model focusing on: mother’s role and autonomy, knowledge and attitude towards feeding of young children, availability of services and resources that shape these practices set against the context of agriculture and livelihood patterns and its contribution to availability of food as well as on migration cycles thereby affecting the lives of ‘left behind’, and access to basic health, education and infrastructure services.ConclusionsThis interdisciplinary and participatory study explored determinants impacting feeding practices across political, village and household environments. These results shaped the process for cocreation of our context-specific intervention package.

ObjectiveIndia has been struggling with infant malnutrition for decades. There is a need to identify suitable platforms for community engagement to promote locally feasible, resource efficient Infant and Young Child Feeding (IYCF) interventions. This study aims to explore if and how schools could represent a site for community engagement in rural India, acting as innovation hubs to foster positive change in partnership with the Angawadi centres.DesignFive-phase formative study; A parallel mixed methods approach structured by a socioecological framework was used for data collection at individual, household and community levels. This paper focuses on the qualitative findings.SettingThis study was undertaken in nine villages within two blocks, ‘Ghatol’ and ‘Kushalgarh’, in the Banswara district of Rajasthan, India.Participants17 schools were identified. Interviews were conducted with local opinion leaders and representatives in the education sector, including principals, schoolteachers, block and district education officers. Across the nine study villages, information was gathered from 67 mothers, 58 paternal grandmothers using Focus Discussion Groups (FDGs) and 49 key respondents in Key Informant Interviews.ResultsSchools were considered an important community resource. Challenges included limited parental participation and student absenteeism; however, several drivers and opportunities were identified, which may render schools a suitable intervention delivery site. Enrolment rates were high, with schools and associated staff encouraging parental involvement and student attendance. Existing initiatives, including the mid-day meal, play opportunities and education on health and hygiene, further highlight the potential reliability of schools as a platform for community mobilisation.ConclusionsSchools have been shown to be functional platforms frequently visited and trusted by community members. With teachers and children as change agents, schools could represent a suitable setting for community mobilisation in future wider scale intervention studies. Expanding the supportive environment around schools will be essential to reinforce healthy IYCF practices in the long term.

Background The interdisciplinary Participatory Approach for Nutrition in Children: Strengthening Health, Education, Engineering and Environment Linkages ( PANChSHEEEL ) study used a participatory approach to develop locally-feasible and tailored solutions to optimise Infant and Young Child Feeding (IYCF) practices at an individual, household, community, and environmental level. This paper aims to evaluate the influence of gender; migration; and Health, Education, Engineering and Environmental (HEEE) factors on IYCF practices, with the primary outcomes being three key complementary-feeding practices of Minimum Dietary Diversity (MDD), Minimum Meal Frequency (MMF) and Minimum Acceptable Diet (MAD). Methods A cross-sectional survey of 325 households with children aged 6–23 months was conducted in nine purposively selected villages in two blocks of Banswara district, Rajasthan, India. A survey tool was developed, translated into the local language, pre-tested, and administered in a gender-sensitive manner. Data-collection processes were standardized to ensure quality measures. Association of the primary outcome with 27 variables was tested using a Chi-square test (Mantel-Haenszel method); backward stepwise regression analysis was conducted to assess the impact of effect modifiers (gender, parental migration). Results Half of the surveyed children were of each gender, and fathers from half of the households were found to have migrated within the previous year to search for additional income. Parental literacy ranged from 60 to 70%. More than half of the households had access to milk-producing animals. Consumption of each of the seven food groups, eggs (4.7% vs 0.7%; p  < 0.02), MDD (10.5% vs 3.2%; p  < 0.02) and MAD (9.4% vs 2.6%; p  < 0.02) were higher for boys than for girls. After controlling for contextual factors, a male child was 4.1 times more likely to get a diet with MDD and 3.8 times more likely to get a diet with MAD. A child from a non-migrant household was 2.0–2.1 times more likely to get a diet with MDD and MAD as compared to a child from a migrant household. However, this association was not found to be statistically significant after regression. Presence of milk-producing animals in households and consumption of milk/milk products by children in the previous 24 h were the other two strong predictors of MDD and MAD, although access to animal milk in the house did not translate to an increase in consumption of milk/milk products by a child. Conclusion Gender discrimination in diet diversity and complementary-feeding practices starts early in childhood with boys having a distinct advantage over girls. In the case of parental migration, further research is required to establish if it has an adverse impact on feeding practices. Emphasis needs to be given to gender issues and other contextual factors when developing strategies to optimise complementary feeding practices. Trial registration With UCL ethics [Ethics ID 4032/002] in United Kingdom and with Sigma IRB [10,025/IRB/D/17–18] in India.

Wound healing is a complex biological process that can be hindered by persistent infections and inflammation, especially in the presence of multidrug-resistant (MDR) bacteria. Silver nanoparticles (AgNPs) have demonstrated significant antimicrobial efficacy; however, concerns regarding their toxicity have limited their therapeutic application. Methods: In this study, we developed a biocompatible Ag-NPs-based hydrogel using Cyperus rotundus extract via a green synthesis approach for prospective wound healing applications. The synthesized AgNPs were characterized for their physicochemical properties, confirming their stability and antibacterial potency against E. coli and S. epidermidis . The Ag-NPs-loaded hydrogel was formulated using Carbopol 974P and evaluated for its physicochemical properties, antibacterial activity, anti-inflammatory potential, and cytotoxicity. Results: Characterization studies confirmed the successful synthesis of AgNPs, exhibiting potent antibacterial, antioxidant, and anti-inflammatory properties. The Ag-NPs-loaded hydrogel demonstrated significant wound contraction in an excision wound model, comparable to standard treatment. Additionally, in vitro safety evaluations confirmed excellent biocompatibility, minimizing toxicity concerns associated with conventional silver formulations. Conclusions: These findings suggest that the developed Ag-NPs-based hydrogel is an effective, natural, and safer alternative for advanced wound care, warranting further clinical validation.