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1 result(s) for "Rwamugema, Elias"
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Increase in Kelch 13 Polymorphisms in Plasmodium falciparum , Southern Rwanda
Increase in Kelch 13 Polymorphisms in Plasmodium falciparum , Southern Rwanda
by Sendegeya, Augustin , Bayingana, Claude , Nshimiyimana, Fabian in Antimalarials - pharmacology , Antimalarials - therapeutic use , Antimicrobial agents
2021
Artemisinin resistance in Plasmodium falciparum is associated with nonsynonymous mutations in the Kelch 13 (K13) propeller domain. We found that 12.1% (8/66) of clinical P. falciparum isolates from Huye district, Rwanda, exhibited K13 mutations, including R561H, a validated resistance marker. K13 mutations appear to be increasing in this region.
Journal Article
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