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127
result(s) for
"Sampath Kumar, R"
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Establishment of a new inequality using extended Heinz type mean
2018
In this paper, the Extended Heinz type function is introduced, and it is proved that the function F[E](a, b;v) is a mean. Further investigated the various properties of mean such as symmetricity, homogeneity, monotonicity and convexity. As an application, some inequalities have been established.
Journal Article
Curcumin-induced inhibition of cellular reactive oxygen species generation: Novel therapeutic implications
by
Koteswari, A. Adaikala
,
Maheswari, J. Uma
,
Kumar, R. Sampath
in
Acetates
,
Acetic acid
,
Anti-inflammatory agents
2003
There is evidence for increased levels of circulating reactive oxygen species (ROS) in diabetics, as indirectly inferred by the findings of increased lipid peroxidation and decreased antioxidant status. Direct measurements of intracellular generation of ROS using fluorescent dyes also demonstrate an association of oxidative stress with diabetes. Although phenolic compounds attenuate oxidative stress-related tissue damage, there are concerns over toxicity of synthetic phenolic antioxidants and this has considerably stimulated interest in investigating the role of natural phenolics in medicinal applications. Curcumin (the primary active principle in turmeric, Curcuma longa Linn.) has been claimed to represent a potential antioxidant and antiinflammatory agent with phytonutrient and bioprotective properties. However there are lack of molecular studies to demonstrate its cellular action and potential molecular targets. In this study the antioxidant effect of curcumin as a function of changes in cellular ROS generation was tested. Our results clearly demonstrate that curcumin abolished both phorbol-12 myristate-13 acetate (PMA) and thapsigargin-induced ROS generation in cells from control and diabetic subjects. The pattern of these ROS inhibitory effects as a function of dose-dependency suggests that curcumin mechanistically interferes with protein kinase C (PKC) and calcium regulation. Simultaneous measurements of ROS and Ca2+ influx suggest that a rise in cytosolic Ca2+ may be a trigger for increased ROS generation. We suggest that the antioxidant and antiangeogenic actions of curcumin, as a mechanism of inhibition of Ca2+ entry and PKC activity, should be further exploited to develop suitable and novel drugs for the treatment of diabetic retinopathy and other diabetic complications.
Journal Article
An efficient localization-based secure resource allocation using e-fso with ss-ddnn-based cm-lsgeo techniques
by
Y R, Sampath Kumar
,
N, Champa H
in
Algorithms
,
Computer Communication Networks
,
Computer Science
2024
Complex applications, as well as multimedia services, are increasing swiftly with the substantial growth of Mobile Users (MUs) and IoT devices; thus, demanding extra computations along with higher data communication. Nevertheless, with limited computation power along with energy, these devices are still resource-constrained. Numerous methodologies have been developed for efficient Resource Allocation (RA) in the cloud; however, owing to the loss of network resources, energy consumption, along lower battery lifetime, the prevailing methodologies are deemed to be ineffective. So, by utilizing an Entropy-centric Fish Swarm Optimization Algorithm (E-FSO) with Soft Swish Deep Dense Neural Network (SS-DDNN)-guided Crossover Mutation – Linear Scaling-centered Golden Eagle Optimization (CM-LSGEO) technique, a practical localization-centric safe RA has been suggested to help with the previously mentioned issues. Initially, the mobile’s optimal location is detected by utilizing the E-FSO algorithm. Next, for the secure transmission of packets, the failure node is detected effectively by employing the SS-DDNN algorithm. By utilizing the CM-LSGEO algorithm, a model has been constructed to perform efficient RA. The performance of the suggested model is compared to that of the current models in the experimental assessment, which takes into account some metrics. The outcomes displayed that in comparison with the prevailing methodologies, the proposed framework is more efficient.
Journal Article
Study of the Analysis of the Corrosion Resistance of Ti6Al4V and CoCrMo Metallic Alloys
by
Chinka, Siva Sankara Babu
,
Rao, Putta Nageswara
,
Kumar, B. Ashok
in
Aerospace industry
,
Aircraft
,
Aluminum
2024
In the automobile, aerospace and other sectors, the use of titanium has enabled several types of applications. Understanding its fundamentals is necessary not only to identify the corrosion mechanisms, but also to prevent it through appropriate protection techniques and to predict the behavior of corrosion in metallic materials under service conditions. Understanding corrosion mechanisms is a key to develop a knowledge-based design of corrosion-resistant alloys and predicting the long-term behavior of metallic materials in corrosive environments. This paper analyzes the corrosion resistance of metallic alloys Ti6Al4V and CoCrMo when immersed in electrolytic solutions. In addition, this paper studies the possible corrosion effects caused by temperature, pH and immersion time conditions and carry out electrochemical tests such as: OCP; ECIS and polarization curve. From the obtained data, observe the behavior of Ti6Al4V and CoCrMo alloys.
Journal Article
Photoperiod and temperature affects seasonal ovarian gene expression of p450 aromatase and gonadotropin receptors in Atlantic Salmon (Salmo salar L.) broodstock
by
Andersson, Eva
,
Stefansson, Sigurd Olav
,
Kumar, Sampath R.
in
Aquaculture
,
Brackish
,
Freshwater
2003
Photoperiod and temperature modulated the seasonal pattern of ovarian gene expression of P450 aromatase, Follicle-Stimulating Hormone receptor and Luteinizing Hormone receptor in Atlantic salmon broodstock.
Journal Article
A Study On Recent Advancements In Bio-Metric Identity Verification
2014
Security plays an important role in day to day life of a human being. Bio-Metric is the study of identification of persons based on his physical or behavioural characteristic. The different methods for verifying identity of a person ranges from finger prints to heart beats. The input taken from the user may be from a single source or multiple sources. In case of multiple sources the combinations may be at different levels. The performance of these methods varies according to the parameters used for a person identification. The study is on the latest new techniques adopted in Biometrics. The focus is on Heart Beat sound, Face recognition invariant to plastic surgery , touch less finger print and keystroke methods.
Journal Article
Variable-attribute mixed sampling plans by intervened random effect Poisson Distribution
by
Sekkizhar, J
,
Kumar, R Sampath
,
Radhakrishnan, R
in
Classical studies
,
Construction
,
Engineers
2010
The decision whether to accept or reject the manufactured lot is to be made in any company in the last part of the production process. Several parameters such as AQL, LQL, IQL, MAPD are used in the construction of sampling plan. There are many methods available for acceptance testing, but Acceptance Sampling plans which take into account the Acceptable Quality Level (AQL) and Lot Tolerance Percent Defective (LTPD or LQL) are considered to be the most statistically valid. In this department the engineer has to decide on the nature of sampling plan to be adopted. Mixed sampling plan (MSP) is a double-sampling procedure involving variables inspection of the first sample and subsequent attributes inspection in the second sample if the variables inspection of the first sample does not lead to acceptance. Classical studies in the construction sampling plans are based on Poisson distribution as baseline distribution. Radhakrishnan and Sekkizhar (2007a, 2007b and 2007c) introduced intervened random effect Poisson distribution (IRPD) in the place of Poisson distribution for the construction of attribute sampling plans. Quality engineers are always interested in improving the quality level of the product to enhance the satisfaction of the customers and hence, they keep changes in the production process. IRPD is helpful for modeling such situations. This paper presents a procedure for constructing the MSP using IRPD using producer and consumer risks. Having the single sampling plan as attribute plan, the plan is constructed through acceptable and limiting quality level. Tables are constructed for easy selection of the plan.
Journal Article
Central Asian Economic Integration: Emerging Trends
1998
Despite their strong urge for economic co-operation, the central Asian states are finding it difficult putting co-operative economic union into practice. Lack of diversification and lack of infrastructure, is making them fall prey to the extractive economic policies of their big neighbour, Russia. Moreover, there is no consensus among the CAS regarding the path of economic development they should adopt. Nevertheless, the fact remains that the CAS have come to realise the desirability of mutual exchange and hope greater success in near future.
Journal Article