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In this paper, we present an onboard monocular vision system for autonomous takeoff, hovering and landing of a Micro Aerial Vehicle (MAV). Since pose information with metric scale is critical for autonomous flight of a MAV, we present a novel solution to six degrees of freedom (DOF) pose estimation. It is based on a single image of a typical landing pad which consists of the letter “H” surrounded by a circle. A vision algorithm for robust and real-time landing pad recognition is implemented. Then the 5 DOF pose is estimated from the elliptic projection of the circle by using projective geometry. The remaining geometric ambiguity is resolved by incorporating the gravity vector estimated by the inertial measurement unit (IMU). The last degree of freedom pose, yaw angle of the MAV, is estimated from the ellipse fitted from the letter “H”. The efficiency of the presented vision system is demonstrated comprehensively by comparing it to ground truth data provided by a tracking system and by using its pose estimates as control inputs to autonomous flights of a quadrotor.

Many aerial robotic applications require the ability to land on moving platforms, such as delivery trucks and marine research boats. We present a method to autonomously land an Unmanned Aerial Vehicle on a moving vehicle. A visual servoing controller approaches the ground vehicle using velocity commands calculated directly in image space. The control laws generate velocity commands in all three dimensions, eliminating the need for a separate height controller. The method has shown the ability to approach and land on the moving deck in simulation, indoor and outdoor environments, and compared to the other available methods, it has provided the fastest landing approach. Unlike many existing methods for landing on fast-moving platforms, this method does not rely on additional external setups, such as RTK, motion capture system, ground station, offboard processing, or communication with the vehicle, and it requires only the minimal set of hardware and localization sensors. The videos and source codes are also provided.

State estimation is the most critical capability for MAV (Micro-Aerial Vehicle) localization, autonomous obstacle avoidance, robust flight control and 3D environmental mapping. There are three main challenges for MAV state estimation: (1) it can deal with aggressive 6 DOF (Degree Of Freedom) motion; (2) it should be robust to intermittent GPS (Global Positioning System) (even GPS-denied) situations; (3) it should work well both for low- and high-altitude flight. In this paper, we present a state estimation technique by fusing long-range stereo visual odometry, GPS, barometric and IMU (Inertial Measurement Unit) measurements. The new estimation system has two main parts, a stochastic cloning EKF (Extended Kalman Filter) estimator that loosely fuses both absolute state measurements (GPS, barometer) and the relative state measurements (IMU, visual odometry), and is derived and discussed in detail. A long-range stereo visual odometry is proposed for high-altitude MAV odometry calculation by using both multi-view stereo triangulation and a multi-view stereo inverse depth filter. The odometry takes the EKF information (IMU integral) for robust camera pose tracking and image feature matching, and the stereo odometry output serves as the relative measurements for the update of the state estimation. Experimental results on a benchmark dataset and our real flight dataset show the effectiveness of the proposed state estimation system, especially for the aggressive, intermittent GPS and high-altitude MAV flight.

Inflammasomes are multiprotein complexes that control the innate immune response by activating caspase-1, thus promoting the secretion of cytokines in response to invading pathogens and endogenous triggers. Assembly of inflammasomes is induced by activation of a receptor protein. Many inflammasome receptors require the adapter protein ASC [apoptosis-associated speck-like protein containing a caspase-recruitment domain (CARD)], which consists of two domains, the N-terminal pyrin domain (PYD) and the C-terminal CARD. Upon activation, ASC forms large oligomeric filaments, which facilitate procaspase-1 recruitment. Here, we characterize the structure and filament formation of mouse ASC in vitro at atomic resolution. Information from cryo-electron microscopy and solid-state NMR spectroscopy is combined in a single structure calculation to obtain the atomic-resolution structure of the ASC filament. Perturbations of NMR resonances upon filament formation monitor the specific binding interfaces of ASC-PYD association. Importantly, NMR experiments show the rigidity of the PYD forming the core of the filament as well as the high mobility of the CARD relative to this core. The findings are validated by structure-based mutagenesis experiments in cultured macrophages. The 3D structure of the mouse ASC-PYD filament is highly similar to the recently determined human ASC-PYD filament, suggesting evolutionary conservation of ASC-dependent inflammasome mechanisms.

This paper presents a novel solution for micro aerial vehicles (MAVs) to autonomously search for and land on an arbitrary landing site using real-time monocular vision. The autonomous MAV is provided with only one single reference image of the landing site with an unknown size before initiating this task. We extend a well-known monocular visual SLAM algorithm that enables autonomous navigation of the MAV in unknown environments, in order to search for such landing sites. Furthermore, a multi-scale ORB feature based method is implemented and integrated into the SLAM framework for landing site detection. We use a RANSAC-based method to locate the landing site within the map of the SLAM system, taking advantage of those map points associated with the detected landing site. We demonstrate the efficiency of the presented vision system in autonomous flights, both indoor and in challenging outdoor environment.

We autonomously directed a small quadcopter package delivery Uncrewed Aerial Vehicle (UAV) or “drone” to take off, fly a specified route, and land for a total of 209 flights while varying a set of operational parameters. The vehicle was equipped with onboard sensors, including GPS, IMU, voltage and current sensors, and an ultrasonic anemometer, to collect high-resolution data on the inertial states, wind speed, and power consumption. Operational parameters, such as commanded ground speed, payload, and cruise altitude, were varied for each flight. This large data set has a total flight time of 10 hours and 45 minutes and was collected from April to October of 2019 covering a total distance of approximately 65 kilometers. The data collected were validated by comparing flights with similar operational parameters. We believe these data will be of great interest to the research and industrial communities, who can use the data to improve UAV designs, safety, and energy efficiency, as well as advance the physical understanding of in-flight operations for package delivery drones. Measurement(s) atmospheric wind speed • atmospheric wind direction • battery current • battery voltage • position Technology Type(s) anemometer • Current / Voltage measurement sensor • GPS navigation system • inertial measurement unit Factor Type(s) programmed speed during cruise • programmed altitude during cruise • payload mass Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.13814225

We introduce TartanAviation, an open-source multi-modal dataset focused on terminal-area airspace operations. TartanAviation provides a holistic view of the airport environment by concurrently collecting image, speech, and ADS-B trajectory data using setups installed inside airport boundaries. The datasets were collected at both towered and non-towered airfields across multiple months to capture diversity in aircraft operations, seasons, aircraft types, and weather conditions. In total, TartanAviation provides 3.1M images, 3374 hours of Air Traffic Control speech data, and 661 days of ADS-B trajectory data. In addition to the raw data, we provide post-processed versions with synchronized, filtered, and interpolated data. In addition to the dataset, we also open-source the code-base used to collect and pre-process the dataset, further enhancing accessibility and usability. We believe this dataset has many potential use cases and would be particularly vital in allowing AI and machine learning technologies to be integrated into air traffic control systems and advance the adoption of autonomous aircraft in the airspace.

Detecting and finding people are complex tasks when visibility is reduced. This happens, for example, if a fire occurs. In these situations, heat sources and large amounts of smoke are generated. Under these circumstances, locating survivors using thermal or conventional cameras is not possible and it is necessary to use alternative techniques. The challenge of this work was to analyze if it is feasible the integration of an acoustic camera, developed at the University of Valladolid, on an unmanned aerial vehicle (UAV) to locate, by sound, people who are calling for help, in enclosed environments with reduced visibility. The acoustic array, based on MEMS (micro-electro-mechanical system) microphones, locates acoustic sources in space, and the UAV navigates autonomously by closed enclosures. This paper presents the first experimental results locating the angles of arrival of multiple sound sources, including the cries for help of a person, in an enclosed environment. The results are promising, as the system proves able to discriminate the noise generated by the propellers of the UAV, at the same time it identifies the angles of arrival of the direct sound signal and its first echoes reflected on the reflective surfaces.

ABC toxins are pore-forming virulence factors produced by pathogenic bacteria. YenTcA is the pore-forming and membrane binding A subunit of the ABC toxin YenTc, produced by the insect pathogen Yersinia entomophaga . Here we present cryo-EM structures of YenTcA, purified from the native source. The soluble pre-pore structure, determined at an average resolution of 4.4 Å, reveals a pentameric assembly that in contrast to other characterised ABC toxins is formed by two TcA-like proteins (YenA1 and YenA2) and decorated by two endochitinases (Chi1 and Chi2). We also identify conformational changes that accompany membrane pore formation by visualising YenTcA inserted into liposomes. A clear outward rotation of the Chi1 subunits allows for access of the protruding translocation pore to the membrane. Our results highlight structural and functional diversity within the ABC toxin subfamily, explaining how different ABC toxins are capable of recognising diverse hosts. YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga . Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associated endochitinases in host cell recognition.

Autonomous bridge inspection operations using unmanned aerial vehicles take multiple task assignments and constraints into account. To efficiently execute the operations, a schedule is required. Generating a cost optimum schedule of multiple-unmanned aerial vehicle operations is known to be Non-deterministic Polynomial-time (NP)-hard. This study approaches such a problem with heuristic-based algorithms to get a high-quality feasible solution in a short computation time. A constructive heuristic called Retractable Chain Task Assignment algorithm is presented to build an evaluable schedule from a task sequence. The task sequence representation is used during the search to perform seamless operations. Retractable Chain Task Assignment algorithm calculates and incorporates slack time to the schedule according to the properties of the task. The slack time acts as a cushion which makes the schedule delay-tolerant. This algorithm is incorporated with a metaheuristic algorithm called Multi-strategy Coevolution to search the solution space. The proposed algorithm is verified through numerical simulations, which take inputs from real flight test data. The obtained solutions are evaluated based on the makespan, battery consumption, computation time, and the robustness level of the schedules. The performance of Multi-strategy Coevolution is compared to Differential Evolution, Particle Swarm Optimization, and Differential Evolution–Fused Particle Swarm Optimization. The simulation results show that Multi-strategy Coevolution gives better objective values than the other algorithms.