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BACKGROUND: Negative affective and pain‐related cues, such as pictures or words, have been shown to act as primes and enhance the perceived intensity of subsequent painful events. For pain‐related semantic primes, it remains unclear whether this effect depends on negative valence itself or, specifically, on the pain‐relatedness of the words. OBJECTIVES: To investigate the effect of pain‐related, negative affective (pain‐unrelated) and neutral semantic primes on the perception of subsequent noxious target stimuli. METHODS: Pain ratings in response to noxious electrical stimulation of light and moderate intensity were examined in 39 healthy subjects after subjects were exposed to semantic primes of different meaning and valence (pain‐related, negative, positive and neutral adjectives) presented with different interstimulus intervals (0 ms, 500 ms and 1500 ms). RESULTS: Increased pain ratings of noxious stimuli were observed following pain‐related and negative compared with neutral primes. DISCUSSION: The results support the motivational priming theory for semantic stimuli, indicating that affectively negative semantic primes increase subjective pain intensity. However, a specific pain‐related priming effect was not reliably demonstrated. Additionally, it is shown that experimental parameters (ie, stimulus intensity and interstimulus interval) modify the extent of negative and pain‐related semantic priming. CONCLUSIONS: Verbal priming plays a role for the perception of noxious stimuli in a time‐dependent manner.

Agricultural production finds itself in an area of tension. As a critical infrastructure, it has the task of reliably feeding a growing global population and supplying it with energy. However, the negative environmental impacts caused by agriculture, such as the global loss of biodiversity and the emission of greenhouse gases, are to be reduced. The increasing use of digital technologies is often described as a panacea that enables sustainable agriculture. The relevant literature is very dynamic, but the large number of concepts and terminologies used makes it difficult to obtain an overall view. In addition, many contributions focus on presumed or modeled efficiency gains, but this ignores technical and societal prerequisites and barriers. Therefore, the aim of this work was to identify the opportunities and risks of smart farming (SF) for more ecological arable farming. For this purpose, a holistic and environmental view was taken. The potential of SF to aid in the reduction in the environmental impacts of individual agricultural work steps was examined via an analysis of current literature. In addition, rebound effects, acceptance barriers and political omissions were considered as risks that prevent the benefits from being realized. It was shown that SF is able to contribute to a significant reduction in the negative environmental effects of agriculture. In particular, a reduction in fertilizer and pesticide application rates through mapping, sensing and precise application can lead to environmental benefits. However, achieving this requires the minimization of existing risks. For this reason, a proactive role of the state is required, implementing the necessary governance measures.

Introduction The purpose of this investigation was to compare clinical outcome, component loosening, polyethylene cup wear and periprosthetic bone mineral density between “cup first” navigated and conventional cementless total hip arthroplasty (THA) 5–7 years after surgery. Materials and methods Fifty patients who received THA with ( n  = 25) or without ( n  = 25) the use of an image-free navigation system by a single surgeon were investigated after a mean follow-up of 6.4 (4.8–7.4) years. The Hip Osteoarthritis Outcome Score (HOOS) and the Harris Hip Score (HHS) were obtained; range-of-motion (ROM) was evaluated by a blinded examiner. Radiographic cup inclination, signs of radiographic loosening and polyethylene wear were analysed with the help of digital analysis software on anterio-posterior radiographs by a blinded examiner. Acetabular and femoral periprosthetic bone density was evaluated with the help of dual-energy X-ray absorptiometry. Results We were unable to find any statistical significant or clinically relevant difference for the HOOS, HHS, ROM and polyethylene wear between the navigated and the conventional THA group 5–7 years after surgery. Cup inclination was more precise in the navigated THA group in relation to the target value of 45°. Conclusions Standard “cup first” THA navigation does not improve mid-term functional outcome, bony ingrowth and/or polyethylene wear. New concepts in computer-assisted THA, considering cup and stem as coupled biomechanical partners are needed to justify the effort of navigation in routine operations.

Colorectal cancer remains one of the most commonly diagnosed cancers. Advanced rectal cancer patients receive neoadjuvant radiochemotherapy as well as surgery and suffer from reduced health-related quality of life due to various side effects. We were interested in the role of the COVID-19 pandemic and how it affected those patients’ quality of life. A total of 489 advanced rectal cancer patients from the University Hospital Erlangen in Germany were surveyed between May 2010 and March 2022 and asked to fill out the EORTC QLQ-C30 and QLQ-CR38 questionnaires over eight different time points: at the beginning, during and after radiochemotherapy, right before surgery, and in yearly intervals after surgery for up to four years. Answers were converted to scores to compare the COVID-19 period to the time before March 2020, focusing on the follow-ups, the developments over time—including by sex and age—and the influence of the TNM cT-stage. Overall, a trend of impaired functional and symptom scores was found across all surveys with few significances (body image −10.6 percentage points (pp) after one year; defecation problems +13.5 pp, insomnia +10.2 pp and weight loss +9.8 pp after three years; defecation problems +11.3 pp after four years). cT4-stage patients lost significantly more weight than their cT1-3-stage counterparts (+10.7 to 13.7 pp). Further studies should be conducted to find possible causes and develop countermeasures for future major infectious diseases.

In recent years, rewilding has been attracting growing attention as novel, process‐oriented concept supporting ecosystem restoration and biodiversity conservation. Rewilding aims to strengthen the adaptive capacity of ecosystems by restoring natural processes and withdrawing anthropogenic interventions. Yet, diverging understandings, conceptions and definitions of rewilding result in a somewhat fuzzy concept. So far, the scientific discussion focused primarily on biological and ecological effects and success factors of rewilding. However, particularly in Europe, which is characterised by densely populated areas and a long history of landscape cultivation, rewilding affects also socio‐economic and socio‐cultural dimensions Based on a synthesis of current scientific publications, we argue that rewilding should be understood as an increase in wildness, that is restoring the autonomy of natural processes and self‐sustaining ecosystems in order to overcome the improper dualistic understanding of human‐nature relationships in which humanity is outside of nature. We identify knowledge gaps and emphasise the need for inter‐ and transdisciplinary research on rewilding to develop a holistic approach to biodiversity conservation and ecosystem restoration. In this context, we particularly emphasise the temporal dynamics of changes in landscapes, which are often long‐term and therefore difficult to monitor, the openness of rewilding processes and the associated uncertainty about end states, as well as the complexity of human‐nature relations and the associated value pluralism. Read the free Plain Language Summary for this article on the Journal blog. Read the free Plain Language Summary for this article on the Journal blog.

Rapid expansion of settlements and related infrastructures is a global trend that comes with severe environmental, economic, and social costs. Steering urbanization toward well-balanced compactness is thus acknowledged as an important strategic orientation in UN Sustainable Development Goal 11 (SDG-11) via the SDG-indicator “Ratio of land consumption rate to population growth rate.” The EU’s simultaneous commitment to being “a frontrunner in implementing […] the SDGs” and to striving for “no net land take until 2050” calls for relating the concepts of land consumption and land take to each other. Drawing on an EU-centred questionnaire study, a focus group and a literature review, we scrutinize definitions of land consumption and land take, seeking to show how they are interrelated, and questioning the comparability of respective indicators. We argue that conceptual clarifications and a bridging of the two notions are much needed, and that the precision required for definitions and applications is context-dependent. While approximate understandings may suffice for general communication and dissemination objectives, accurate and consistent interpretations of the discussed concepts seem indispensable for monitoring and reporting purposes. We propose ways of addressing existing ambiguities and suggest prioritizing the term land take in the EU context. Thereby, we aim to enhance conceptual clarity around land consumption and land take—a precondition for solidly informing respective policies and decisions.

Habitat banking and tradable development rights (TDR) have gained considerable currency as a way of achieving ‘no net loss’ of biodiversity and of reconciling nature conservation with economic development goals. This paper reviews the use of these instruments for biodiversity conservation and assesses their roles in the policy mix. The two instruments are compared in terms of effectiveness, cost effectiveness, social impact, institutional context and legal requirements. The role in the policy mix is discussed highlighting sequential relationships, as well as complementarities or synergies, redundancy and conflicts with other instruments, such as biodiversity offsets and land-use zoning. Habitat banking and TDR have the potential to contribute to biodiversity conservation objectives and attain cost-effective solutions with positive social impacts on local communities and landowners. They can also help to create a new mind-set more favourable to public-private cooperation in biodiversity conservation. At the same time, these policy instruments face a number of theoretical and implementation challenges, such as additionality and equivalence of offsets, endurance of land-use planning regulations, monitoring of offset performance, or time lags between restoration and resulting conservation benefits. A clear, enforceable regulatory approach is a prerequisite for the success of habitat banking and TDR. In return, these schemes provide powerful incentives for compliance with regulatory norms and ensure a more equitable allocation of the benefits and costs of land-use controls and conservation. Environmentally harmful subsidies in other policy sectors as well as alternative offset options, however, reduce the attractiveness and effectiveness of these instruments. Thus, the overall performance of habitat banking and TDR hinges on how they are integrated into the biodiversity conservation policy mix and fine-tuned with other sectoral policies.

The development and use of the conceptual framework of ecosystem services (ES) has been very successful in supporting the broad diffusion and application of ES within science and policy communities. However, most of the currently proposed interpretations of the framework neither correlate to environmental planning nor to decision-making contexts at the local and regional scale, which is a potential reason for the slow adoption and practice of the ES conceptual framework. This paper proposes a practice-oriented ES evaluation (PRESET) model specifically adapted to the requirements of local and regional planning and decision-making contexts, and discusses its potential benefits and implications for practice. Through the usage of PRESET we suggest making a distinction between ‘offered ES’, ‘utilized ES’, ‘human input’, and ‘ES benefits’ as relevant information for decision-making. Furthermore, we consider it important to link these decision-support categories to different value dimensions relevant in planning and management practice. PRESET provides guidance to inject the ES concept into planning, but needs to be implemented together with concrete assessment methods, indicators and data. The planning strategic benefits of using PRESET include its reference to existing legislative objectives, avoiding the risk that monetized ES values might dominate decision-making, clarification of human contributions, and easier identification of land use conflicts and synergies. Examples are given for offered and utilized ES, as well as for respective evaluation approaches and instruments of implementation.

Governance of natural resources is inherently complex and requires navigating trade-offs at multiple dimensions. In this paper, we present and operationalize the “governance disruptions framework” (GDF) as a tool for holistic analysis of natural resource governance systems. For each of the four dimensions of the framework (target adequacy, object adequacy, instrument adequacy, and behavioural adequacy), we formulate guiding questions to be used when applying the framework to particular governance systems. We then demonstrate the use of GDF by applying it to the core of German agricultural soil policy. We show that for each framework dimension, the governance system exhibits deficits, particularly with respect to object adequacy and instrument adequacy. Furthermore, we use the GDF-based analysis to highlight research gaps. We find that stakeholder analyses are a central gap across GDF dimensions.