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"Scotton, Rob"
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Splish, splash, Splat!
Splat does not want to have a playdate with Spike and both are afraid to learn how to swim. When the rest of their classmates rush straight into the pool, Splat and Spike find that they may have more in common than they thought.
Book
Turtle's Favorite Books
An excerpt from Russell and the Lost Treasure written and illustrated by Rob Scotton is presented.
Magazine Article
Max and Moonbean
\"It's the night before the big show-and-tell, and Max isn't sure what to bring. He's shy and worried that it will all go all wrong. But when a space creature named Moonbean crashes into his room, Max discovers all he needed was a friend to help him find his confidence. Heartfelt and whimsically illustrated, Max and Moonbean is an empowering picture book story about friendship, bravery, and daring to dream big from one of the best-selling picture book creators of all-time, Rob Scotton.\" -- Publisher marketing.
Book
Association between hyperglycaemia, diabetes complications and development of fibrotic conditions among people living with type 1 and type 2 diabetes in England: a retrospective cohort study using UK Clinical Resource Datalink Aurum and Hospital Episode Statistics
ObjectiveFibrosis is a pathological feature that can occur in a wide range of diseases including diabetes mellitus. We investigated whether in people with type 1 (T1DM) or type 2 diabetes mellitus (T2DM), glycaemia or diabetes-related complications are associated with fibrotic diseases.Design and settingRetrospective cohort study using UK Clinical Resource Datalink (CPRD) Aurum and Hospital Episode Statistics.ParticipantsWe included people with prevalent T1DM or T2DM as of 31 December 2015 (recorded in CPRD Aurum), eligible for linkage with Hospital Episode Statistics and followed up for 3 years.Outcome measuresWe defined diabetes status using blood/urine biomarkers and complications. In the T2DM cohort, we also investigated exposures of hyperglycaemia, insulin resistance and metformin prescription. Fibrotic condition diagnoses were determined from both primary and secondary care records. Logistic regression analyses were undertaken to understand the strength of association between diabetes status/diabetic complications and fibrotic conditions, respectively.ResultsThe T1DM cohort consisted of 9669 people while the T2DM cohort included 504 066 people. In T1DM, we found that albuminuria was associated with lung fibrosis (ORadj: 2.07, 99% CI 1.35 to 2.17), and microvascular complications were associated with atherosclerosis (ORadj: 1.81, 99% CI 1.18 to 2.77) and cardiomyopathy (ORadj 1.53, 99% CI:1.15 to 2.04). In the T2DM cohort, both glycaemia above target and diabetes complications were associated with most fibrotic conditions.ConclusionsWithin the T1DM population, no consistent association between diabetes status and all fibrotic diseases was observed. More research is required to understand whether the association between diabetes complications and fibrotic diseases is due to shared risk factors or whether glycaemia in T2DM may be influenced by fibrotic pathology.
Journal Article
Splat the Cat : blow, snow, blow
Splat the Cat can't wait for enough snow to fall, so he decides he will make it snow somehow.
Book
Chronic pancreatitis: a case ascertainment study
BackgroundChronic pancreatitis (CP) is a debilitating condition, characterised by chronic inflammation and fibrosis of the pancreas. The population frequency of CP is poorly understood. Therefore, we used a broad pragmatic approach to estimate the frequency of CP among a patient population undergoing investigations at a UK tertiary university hospital.MethodAll adult patients who, during 2006–2014, underwent abdominal CT MRI, abdominal X-ray, endoscopic ultrasonography (EUS), faecal elastase testing, received a pancreatin prescription or a recorded primary/comorbid ICD diagnosis of CP were screened (screening cohort) for inclusion. By applying the well-recognised CT, MRI and EUS criteria to the screening cohort, patients with CP were identified (study cohort). The incidence and point prevalence of CP were calculated, and changes in incidence were modelled using Poisson regression.ResultsScreening cohort included 24 271 cases, and 1003 patients who met the diagnostic criteria for CP were included in the study cohort. The median age of diagnosis was 65 (IQR 50–76); the majority were males (n=656, 65.4%) and of European ancestry (n=884, 88.1%). The annual incidence of diagnosis increased by a mean of 4.1% per year (95% CI 0.5% to 7.8%; p=0.03) over the study period ranging from 8.5 to 13.8 per 100 000 general population. The point prevalence also increased reaching 53.6 (95% CI 48.3 to 59.4) per 100 000 population at the end of the study period.ConclusionThis study provides a clear method of pragmatically identifying patients with CP in a clinical setting. The incidence of CP diagnosis in patients undergoing investigations in hospital increased gradually in Greater Nottingham.
Journal Article
The name of the game
Looking forward to a fun-filled playdate with his friends Spike and Plank, Splat the Cat is dismayed when things start going wrong, from his fall during a game to his inability to find a good hide-and-seek spot.
Book
Incremental Fermi Large Area Telescope Fourth Source Catalog
We present an incremental version (4FGL-DR3, for Data Release 3) of the fourth Fermi-LAT catalog of gamma-ray sources. Based on the first twelve years of science data in the energy range from 50 MeV to 1 TeV, it contains 6658 sources. The analysis improves on that used for the 4FGL catalog over eight years of data: more sources are fit with curved spectra, we introduce a more robust spectral parameterization for pulsars, and we extend the spectral points to 1 TeV. The spectral parameters, spectral energy distributions, and associations are updated for all sources. Light curves are rebuilt for all sources with 1 yr intervals (not 2 month intervals). Among the 5064 original 4FGL sources, 16 were deleted, 112 are formally below the detection threshold over 12 yr (but are kept in the list), while 74 are newly associated, 10 have an improved association, and seven associations were withdrawn. Pulsars are split explicitly between young and millisecond pulsars. Pulsars and binaries newly detected in LAT sources, as well as more than 100 newly classified blazars, are reported. We add three extended sources and 1607 new point sources, mostly just above the detection threshold, among which eight are considered identified, and 699 have a plausible counterpart at other wavelengths. We discuss degree-scale residuals to the global sky model and clusters of soft unassociated point sources close to the Galactic plane, which are possibly related to limitations of the interstellar emission model and missing extended sources.
Paper
The rain is a pain
Splat the Cat can't wait to try out his new roller skates, but must stay inside because it's raining.
Book
I scream for ice cream
\"Splat and his class go on a field trip to an ice cream factory ... [He] can barely sit still during the bus ride. He's imagining the mountain of ice cream he thinks he'll get to eat. But when Splat gets there, that mountain becomes more of an avalanche. It's up to Splat and his classmates to save the day\"--Amazon.com.
Book