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فان غوغ
كان فان غوغ رساما هولنديا يعرف بالأسلوب الخاص والمميز الذي اتبعه في لوحاته، فكان يبعث فيها الحياة عبر تموجات فرشاته العميقة. غير أن هذا الفنان المذهل تمكن بالكاد أن بيع لوحة واحدة خلال حياته. وحين تقرأ الرسائل المتبادلة بينه وبين أخيه ثيو، قد نفهم بشكل أفضل الأفكار التي كانت تدور في ذهنه.
BOOK
Vanishing skyrmion Hall effect at the angular momentum compensation temperature of a ferrimagnet
In the presence of a magnetic field, the flow of charged particles in a conductor is deflected from the direction of the applied force, which gives rise to the ordinary Hall effect. Analogously, moving skyrmions with non-zero topological charges and finite fictitious magnetic fields exhibit the skyrmion Hall effect, which is detrimental for applications such as skyrmion racetrack memory. It was predicted that the skyrmion Hall effect vanishes for antiferromagnetic skyrmions because their fictitious magnetic field, proportional to net spin density, is zero. Here we investigate the current-driven transverse elongation of pinned ferrimagnetic bubbles. We estimate the skyrmion Hall effect from the angle between the current and the bubble elongation directions. The angle and, hence, the skyrmion Hall effect vanishes at the angular momentum compensation temperature where the net spin density vanishes. Furthermore, our study establishes a direct connection between the fictitious magnetic field and the spin density.The temperature-dependent transverse elongation of ferrimagnetic bubbles provides experimental evidence for an evanescent skyrmion Hall effect at zero spin density.
Journal Article
Different Risk Factors of Proximal Junctional Kyphosis and Proximal Junctional Failure Following Long Instrumented Fusion to the Sacrum for Adult Spinal Deformity: Survivorship Analysis of 160 Patients
Abstract
BACKGROUND: The failure modes, time to development, and clinical relevance are known to differ between proximal junctional kyphosis (PJK) and proximal junctional failure (PJF). However, there are no reports that study the risk factors of PJK and PJF separately.
OBJECTIVE: The aim of this study was to investigate the risk factors for PJK and PJF separately.
METHODS: A retrospective study of 160 consecutive patients who underwent a long instrumented fusion to the sacrum for adult spinal deformity with a minimum follow-up of 2 years was conducted. A separate survivorship analysis of PJK and PJF was performed using the Cox proportional hazards model for the 3 categorical parameters of surgical, radiographic, and patient factors.
RESULTS: PJK developed in 27 patients (16.9%) and PJF in 29 patients (18.1%). The median survival time was 17.0 months for PJK and 3.0 months for PJF. Multivariate analyses revealed that a high body mass index was an independent risk factor for PJK (hazard ratio [HR] = 1.179), whereas the significant risk factors for PJF were older age, the presence of osteoporosis, the uppermost instrumented vertebra level at T11-L1, and a greater preoperative sagittal vertical axis (HR = 1.082, 6.465, 5.236, and 1.017, respectively). A large correction of sagittal deformity was shown to be a risk factor for PJF on univariate analyses, but not on multivariate analyses.
CONCLUSION: PJK developed at a median of 17 months and PJF at a median of 3 months. A high body mass index was an independent risk factor for PJK, whereas older age, osteoporosis, uppermost instrumented vertebra level at the thoracolumbar junction, and greater preoperative sagittal vertical axis were risk factors for PJF.
Journal Article
Prediction of Myoelectric Biomarkers in Post-Stroke Gait
Electromyography (EMG) is sensitive to neuromuscular changes resulting from ischemic stroke and is considered a potential predictive tool of post-stroke gait and rehabilitation management. This study aimed to evaluate the potential myoelectric biomarkers for the classification of stroke-impaired muscular activity of the stroke patient group and the muscular activity of the control healthy adult group. We also proposed an EMG-based gait monitoring system consisting of a portable EMG device, cloud-based data processing, data analytics, and a health advisor service. This system was investigated with 48 stroke patients (mean age 70.6 years, 65% male) admitted into the emergency unit of a hospital and 75 healthy elderly volunteers (mean age 76.3 years, 32% male). EMG was recorded during walking using the portable device at two muscle positions: the bicep femoris muscle and the lateral gastrocnemius muscle of both lower limbs. The statistical result showed that the mean power frequency (MNF), median power frequency (MDF), peak power frequency (PKF), and mean power (MNP) of the stroke group differed significantly from those of the healthy control group. In the machine learning analysis, the neural network model showed the highest classification performance (precision: 88%, specificity: 89%, accuracy: 80%) using the training dataset and highest classification performance (precision: 72%, specificity: 74%, accuracy: 65%) using the testing dataset. This study will be helpful to understand stroke-impaired gait changes and decide post-stroke rehabilitation.
Journal Article
Gastroprotective effect of phytoncide extract from Pinus koraiensis pinecone in Helicobacter pylori infection
For centuries, herbs have been used by traditional therapists around the world to treat gastrointestinal tract disorders, such as gastritis. We hypothesized that the anti-
Helicobacter pylori
properties of phytoncide, which is extracted from pinecone waste, would facilitate use as a natural gastroprotective product to treat gastrointestinal tract disorders. Thus, we investigated
in vitro
antibacterial efficacy against
H. pylori
by agar diffusion assay. To determine the gastroprotective properties of phytoncide, we conducted hematoxylin and eosin staining, performed assays for the detection of the cytotoxin gene, and evaluated pro-inflammatory cytokine expression in
H. pylori
-infected C57BL/6 mice. Phytoncide significantly inhibited the survival of
H. pylor
i in the gastrointestinal system of C57BL/6 mice. Reduction of gastric severity in
H. pylori
-infected mice was associated with reductions in the expression levels of pro-inflammatory cytokines in the gastric mucosa, and of the cytotoxin CagA gene in phytoncide treated groups (
P
< 0.05 and
P
< 0.01). In conclusion, phytoncide significantly inhibited the growth of
H. pylori
in gastro tissue, possibly due to the abundant α-pinene present in the phytoncide as detected by HPLC analysis. Further studies are needed to validate our findings, but we suggest that phytoncide has the potential to be used as a natural ingredient in anti-
H. pylori
products.
Journal Article
فلسفة العنف
يتناول كتاب (فلسفة العنف) والذي قام بتأليفه (إلزا دورلان) في حوالي (254) صفحة من القطع المتوسط موضوع (العنف) مستعرضا المحتويات التالية : تصنيع الأجساد العزل، الدفاع عن النفس الدفاع عن الأمة، عهود الدفاع الذاتي، الدولة أو منع احتكار الدفاع المشروع عن النفس، العدالة البيضاء، الدفاع الذاتي السلطة للشعب، الدفاع الذاتي والأمان، الرد.
Book
High-fiber diets attenuate emphysema development via modulation of gut microbiota and metabolism
Dietary fiber functions as a prebiotic to determine the gut microbe composition. The gut microbiota influences the metabolic functions and immune responses in human health. The gut microbiota and metabolites produced by various dietary components not only modulate immunity but also impact various organs. Although recent findings have suggested that microbial dysbiosis is associated with several respiratory diseases, including asthma, cystic fibrosis, and allergy, the role of microbiota and metabolites produced by dietary nutrients with respect to pulmonary disease remains unclear. Therefore, we explored whether the gut microbiota and metabolites produced by dietary fiber components could influence a cigarette smoking (CS)-exposed emphysema model. In this study, it was demonstrated that a high-fiber diet including non-fermentable cellulose and fermentable pectin attenuated the pathological changes associated with emphysema progression and the inflammatory response in CS-exposed emphysema mice. Moreover, we observed that different types of dietary fiber could modulate the diversity of gut microbiota and differentially impacted anabolism including the generation of short-chain fatty acids, bile acids, and sphingolipids. Overall, the results of this study indicate that high-fiber diets play a beneficial role in the gut microbiota-metabolite modulation and substantially affect CS-exposed emphysema mice. Furthermore, this study suggests the therapeutic potential of gut microbiota and metabolites from a high-fiber diet in emphysema via local and systemic inflammation inhibition, which may be useful in the development of a new COPD treatment plan.
Journal Article