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Seibert edits interviews with Overtone Records founder Richard Burns prior to Burns's death in November 2002. In the article, Burns comments on his love of classical music, which was developed as a teen while listening to Metropolitan Opera broadcasts. He goes on to describe his experiences with Overtone Records, during which he issued 17 recordings, most of which had some connection to the music scene in his hometown of New Haven, Connecticut. A discography of recordings he produced is included.

I have been a professional venture capitalist since January 1960. I have seen the creation of thousands of jobs in new ventures and industries by my efforts and the efforts of associates in the venture-capital industry.

I have been a professional venture capitalist since January 1960. I have seen the creation of thousands of jobs in new ventures and industries by my efforts and the efforts of associates in the venture-capital industry.

I have been a professional venture capitalist since January 1960. I have seen the creation of thousands of jobs in new ventures and industries by my efforts and the efforts of associates in the venture-capital industry.

I have been a professional venture capitalist since January 1960. I have seen the creation of thousands of jobs in new ventures and industries by my efforts and the efforts of associates in the venture-capital industry.

I have been a professional venture capitalist since January 1960. I have seen the creation of thousands of jobs in new ventures and industries by my efforts and the efforts of associates in the venture-capital industry.

I have been a professional venture capitalist since January 1960. I have seen the creation of thousands of jobs in new ventures and industries by my efforts and the efforts of associates in the venture-capital industry.

•Genetic variants affecting one cortical region often affect other cortical regions.•Standard mass-univariate methods ignore the distributed nature of genetic effects.•Multivariate MOSTest method exploits distributed effects boosting genetic discovery.•Considering fine-grained vertex-wise measures improves genetic discovery further.•Obtained increase in discovery does not come at a cost of poorer generalizability. Brain morphology has been shown to be highly heritable, yet only a small portion of the heritability is explained by the genetic variants discovered so far. Here we extended the Multivariate Omnibus Statistical Test (MOSTest) and applied it to genome-wide association studies (GWAS) of vertex-wise structural magnetic resonance imaging (MRI) cortical measures from N=35,657 participants in the UK Biobank. We identified 695 loci for cortical surface area and 539 for cortical thickness, in total 780 unique genetic loci associated with cortical morphology robustly replicated in 8,060 children of mixed ethnicity from the Adolescent Brain Cognitive Development (ABCD) Study®. This reflects more than 8-fold increase in genetic discovery at no cost to generalizability compared to the commonly used univariate GWAS methods applied to region of interest (ROI) data. Functional follow up including gene-based analyses implicated 10% of all protein-coding genes and pointed towards pathways involved in neurogenesis and cell differentiation. Power analysis indicated that applying the MOSTest to vertex-wise structural MRI data triples the effective sample size compared to conventional univariate GWAS approaches. The large boost in power obtained with the vertex-wise MOSTest together with pronounced replication rates and highlighted biologically meaningful pathways underscores the advantage of multivariate approaches in the context of highly distributed polygenic architecture of the human brain.