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"Seifan, Mostafa"
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Microbially induced calcium carbonate precipitation: a widespread phenomenon in the biological world
2019
Biodeposition of minerals is a widespread phenomenon in the biological world and is mediated by bacteria, fungi, protists, and plants. Calcium carbonate is one of those minerals that naturally precipitate as a by-product of microbial metabolic activities. Over recent years, microbially induced calcium carbonate precipitation (MICP) has been proposed as a potent solution to address many environmental and engineering issues. However, for being a viable alternative to conventional techniques as well as being financially and industrially competitive, various challenges need to be overcome. In this review, the detailed metabolic pathways, including ammonification of amino acids, dissimilatory reduction of nitrate, and urea degradation (ureolysis), along with the potent bacteria and the favorable conditions for precipitation of calcium carbonate, are explained. Moreover, this review highlights the potential environmental and engineering applications of MICP, including restoration of stones and concrete, improvement of soil properties, sand consolidation, bioremediation of contaminants, and carbon dioxide sequestration. The key research and development questions necessary for near future large-scale applications of this innovative technology are also discussed.
Journal Article
Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications
by
Davani-Davari, Dorna
,
Seifan, Mostafa
,
Negahdaripour, Manica
in
blood circulation
,
foods
,
fructo-oligosaccharides
2019
Prebiotics are a group of nutrients that are degraded by gut microbiota. Their relationship with human overall health has been an area of increasing interest in recent years. They can feed the intestinal microbiota, and their degradation products are short-chain fatty acids that are released into blood circulation, consequently, affecting not only the gastrointestinal tracts but also other distant organs. Fructo-oligosaccharides and galacto-oligosaccharides are the two important groups of prebiotics with beneficial effects on human health. Since low quantities of fructo-oligosaccharides and galacto-oligosaccharides naturally exist in foods, scientists are attempting to produce prebiotics on an industrial scale. Considering the health benefits of prebiotics and their safety, as well as their production and storage advantages compared to probiotics, they seem to be fascinating candidates for promoting human health condition as a replacement or in association with probiotics. This review discusses different aspects of prebiotics, including their crucial role in human well-being.
Journal Article
Circular Economy of Construction and Demolition Waste: A Literature Review on Lessons, Challenges, and Benefits
by
Seifan, Mostafa
,
O’Brien, Bio Talakatoa
,
Kowalewski, Matthew Joseph
in
Circular economy
,
Climate change
,
Construction industry
2021
Conventionally, in a linear economy, C&D (Construction and Demolition) waste was considered as zero value materials, and, as a result of that, most C&D waste materials ended up in landfills. In recent years, with the increase in the awareness around sustainability and resource management, various countries have started to explore new models to minimize the use of limited resources which are currently overused, mismanaged, or quickly depleting. In this regard, the implementation of CE (Circular Economy) has emerged as a potential model to minimize the negative impact of C&D wastes on the environment. However, there are some challenges hindering a full transition to CE in the construction and demolition sectors. Therefore, this review paper aims to critically scrutinize different aspects of C&D waste and how CE can be integrated into construction projects. Reviewing of the literature revealed that the barriers in the implementation of CE in C&D waste sectors fall in five main domains, namely legal, technical, social, behavioral, and economic aspects. In this context, it was found that policy and governance, permits and specifications, technological limitation, quality and performance, knowledge and information, and, finally, the costs associated with the implementation of CE model at the early stage are the main barriers. In addition to these, from the contractors’ perspective, C&D waste dismantling, segregation, and on-site sorting, transportation, and local recovery processes are the main challenges at the start point for small-scale companies. To address the abovementioned challenges, and also to minimize the ambiguity of resulting outcomes by implementing CE in C&D waste sectors, there is an urgent need to introduce a global framework and a practicable pathway to allow companies to implement such models, regardless of their scale and location. Additionally, in this paper, recommendations on the direction for areas of future studies for a reduction in the environmental impacts have been provided. To structure an effective model approach, the future direction should be more focused on dismantling practices, hazardous material handling, quality control on waste acceptance, and material recovery processes, as well as a incentivization mechanism to promote ecological, economic, and social benefits of the CE for C&D sectors.
Journal Article
Microbially induced calcium carbonate precipitation to design a new type of bio self-healing dental composite
by
Aydin, Berenjian
,
Seifan Mostafa
,
Sarabadani Zahra
in
Bacteria
,
Calcium carbonate
,
Chemical precipitation
2020
Crack propagation is one of the issues associating with dental composites which can significantly affect their performance. Current solutions for preventing and stopping the cracks include maximizing the filler to matrix ratio as well as fiber reinforcing of composites which are not always reliable. The precipitation of calcium carbonate (CaCO3) minerals by the generally recognized as safe (GRAS) bacteria can be seen as a novel approach to address this shortcoming. In the present study, the effect of microbially induced calcium carbonate precipitation (MICP) on filling dental composites’ cracks and cavities was studied. In this first step, the capability of different GRAS bacteria to induce CaCO3 precipitation was investigated. In the next step, the capability of potent bacteria to initiate MCIP in solid matrix was evaluated. For this purpose, the CaCO3-bacteria along with necessary nutrients were introduced into different dental composites in two ways, namely, powder and paste form. The light-cured composites were analyzed using optical microscopy, scanning electron microscopy (SEM), and energy-dispersive X-ray (EDS) to identify and characterize the precipitated CaCO3 crystals. It was shown that the incorporation of powder healing compound in two composites resulted in precipitation of CaCO3, while no crystals were formed when a paste form of healing compound was mixed with composites. The results evidently show that MICP can be a feasible alternative to current inefficient approaches to address microcracking issues in dental composites.
Journal Article
Green and Economic Fabrication of Zinc Oxide (ZnO) Nanorods as a Broadband UV Blocker and Antimicrobial Agent
by
Seifan, Mostafa
,
Ebrahiminezhad, Alireza
,
Berenjian, Aydin
in
Algae
,
ANTIBACTERIAL ACTIVITY
,
Antimicrobial activity
2020
Zinc oxide (ZnO) nanoparticles have gained widespread interest due to their unique properties, making them suitable for a range of applications. Several methods for their production are available, and of these, controlled synthesis techniques are particularly favourable. Large-scale culturing of Chlorella vulgaris produces secretory carbohydrates as a waste product, which have been shown to play an important role in directing the particle size and morphology of nanoparticles. In this investigation, ZnO nanorods were produced through a controlled synthesis approach using secretory carbohydrates from C. vulgaris, which presents a cost-effective and sustainable alternative to the existing techniques. Fourier transform infrared (FTIR) spectroscopy, X-ray powder diffraction (XRD) analysis, transmission electron microscopy (TEM), and UV-Vis spectroscopy were used to characterise the nanorods. The prepared nanorods exhibited a broad range of UV absorption, which suggests that the particles are a promising broadband sun blocker and are likely to be effective for the fabrication of sunscreens with protection against both UVB (290–320 nm) and UVA (320–400 nm) radiations. The antimicrobial activity of the prepared nanorods against Gram-positive and Gram-negative bacteria was also assessed. The nanostructures had a crystalline structure and rod-like appearance, with an average length and width of 150 nm and 21 nm, respectively. The nanorods also demonstrated notable antibacterial activity, and 250 μg/mL was determined to be the most effective concentration. The antibacterial properties of the ZnO nanorods suggest its suitability for a range of antimicrobial uses, such as in the food industry and for various biomedical applications.
Journal Article
The effect of aeration and mixing in developing a dairy-based functional food rich in menaquinone-7
2020
Vitamin menaquinone-7 (MK-7) supplementation improves bone health and reduces the incidence of osteoporosis. Despite the recent developments in MK-7 fermentation using Bacillus subtilis natto, low fermentation yields, as well as complicated downstream processing steps, are still the main reasons for the expensive final product. To overcome these issues, developing a fermented dairy-based product rich in MK-7 by avoiding costly downstream steps and optimising the fermentation operating conditions to enhance the MK-7 concentration would be an alternative approach. The present study, therefore, aims to evaluate the role of agitation and aeration as the key operating conditions on MK-7 production by Bacillus subtilis natto using a milk media. The agitation and aeration rates of 525 RPM and 5 VVM were found to be the optimum levels leading to the production of 3.54 mg/L of MK-7. Further, the sensory evaluation was performed to compare the sensory properties of the freeze-dried fermented samples with non-fermented milk samples. The results illustrated that the fermented samples had a significant saltiness with intense aroma resulting in the less acceptability of them by the panellists.
Journal Article
The Effect of Iron Oxide Nanoparticles on the Menaquinone-7 Isomer Composition and Synthesis of the Biologically Significant All-Trans Isomer
by
Neha Lal
,
Mostafa Seifan
,
Aydin Berenjian
in
bacterial cell immobilisation
,
Bioavailability
,
Biological activity
2023
Menaquinone-7 (MK-7) is the most therapeutically valuable K vitamin owing to its excellent bioavailability. MK-7 occurs as geometric isomers, and only all-trans MK-7 is bioactive. The fermentation-based synthesis of MK-7 entails various challenges, primarily the low fermentation yield and numerous downstream processing steps. This raises the cost of production and translates to an expensive final product that is not widely accessible. Iron oxide nanoparticles (IONPs) can potentially overcome these obstacles due to their ability to enhance fermentation productivity and enable process intensification. Nevertheless, utilisation of IONPs in this regard is only beneficial if the biologically active isomer is achieved in the greatest proportion, the investigation of which constituted the objective of this study. IONPs (Fe3O4) with an average size of 11 nm were synthesised and characterised using different analytical techniques, and their effect on isomer production and bacterial growth was assessed. The optimum IONP concentration (300 μg/mL) improved the process output and resulted in a 1.6-fold increase in the all-trans isomer yield compared to the control. This investigation was the first to evaluate the role of IONPs in the synthesis of MK-7 isomers, and its outcomes will assist the development of an efficient fermentation system that favours the production of bioactive MK-7.
Journal Article
The effect of iron oxide nanoparticles on Lactobacillus acidophilus growth at pH 4
by
Novin Donya
,
Aydin, Berenjian
,
Ebrahiminezhad Alireza
in
Bacteria
,
Chemical synthesis
,
Digestive system
2021
Probiotics, in particular, lactic acid bacteria (LAB) are widely used as starter cultures in food and pharmaceutical industries. Presence of LAB supports the production and preservation of a diverse range of food products, provides a positive effect on the human gastrointestinal tract, and prevents the progression of many diseases. However, the main limiting factor in the application of LAB is that they hardly survive in acidic conditions, including the human digestive system. This factor inhibits LAB to maintain their functionality and deliver their health benefits to the host. For this purpose, magnetic immobilisation of LAB with iron oxide nanoparticles (IONs) was conducted to evaluate the effect of IONs on bacterial growth and their viability at low pH. Gram-positive Lactobacillus acidophilus, a well-known species of LAB, was selected for this study. The IONs were successfully synthesised with the average size of 7 nm and used for decoration of L. acidophilus cells at low pH. Based on the results, a 1.8-fold increase in bacterial viability was observed by decorating cells with 360 µg/mL IONs.
Journal Article
Adopting International Learnings to Improve the Performance of New Zealand’s Infrastructure Supply Chain
2021
Growing interest in the productivity of the infrastructure sector has increased due to cost and time overruns in major projects. In this regard, many developed countries have failed to implement a framework to ensure that project success is met through newly available technologies and business initiatives to ensure the user is the most important beneficiary. This review paper provides a review of international research relating to the life cycle, firm-level operations, and collaborative business models of infrastructure projects. The review initially identified the importance that understanding key phases and procurement models has on the efficiency of a project’s life cycle. A key indicator of the likelihood of good performance across a supply chain lies with the ability to understand the efficiencies of the firm-level operations. The literature has noted that successful projects are able to perform well across an organizations end-to-end involvement and be able to share risks among mature organizations. This paper provides a review of how a collaborative business model can benefit a project lifecycle and firm-level operations. The global research currently has identified the need for a collaborative approach that reduces the risk within all organizations through common goals, effective end-to-end project systems and consideration of the entire project lifecycle. The paper provides a detailed review of international practices in an infrastructure supply chain that have the potential to address New Zealand’s infrastructure project failures.
Journal Article
The Effect of Cell Immobilization by Calcium Alginate on Bacterially Induced Calcium Carbonate Precipitation
by
Berenjian, Aydin
,
Hewitt, Shaun
,
Seifan, Mostafa
in
Alginic acid
,
Bacteria
,
biomineralization
2017
Microbially induced mineral precipitation is recognized as a widespread phenomenon in nature. A diverse range of minerals including carbonate, sulphides, silicates, and phosphates can be produced through biomineralization. Calcium carbonate (CaCO3) is one of the most common substances used in various industries and is mostly extracted by mining. In recent years, production of CaCO3 by bacteria has drawn much attention because it is an environmentally- and health-friendly pathway. Although CaCO3 can be produced by some genera of bacteria through autotrophic and heterotrophic pathways, the possibility of producing CaCO3 in different environmental conditions has remained a challenge to determine. In this study, calcium alginate was proposed as a protective carrier to increase the bacterial tolerance to extreme environmental conditions. The model showed that the highest concentration of CaCO3 is achieved when the bacterial cells are immobilized in the calcium alginate beads fabricated using 1.38% w/v Na-alginate and 0.13 M CaCl2.
Journal Article