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Backround The study was planned to evaluate the safety attitudes of mothers with children aged 0–6 years towards home accidents and their self-efficacy in first aid. Method In this cross-sectional study, 438 mothers aged 18 years and older participated. Self-completed questionnaires, sociodemographic and home accident history questions, the Scale for Identifying Maternal Safety Precautions for Home Accidents in Children 0–6 Years of Age, and the First Aid Self-Efficacy in Home Accidents Scale were employed as data collection tools. Results The study revealed that 35.2% of mothers with children aged 0–6 years reported experiencing at least one home accident. Among the reported incidents, it was found that 41.6% were attributed to falls, while 25.3% were related to burns, making them the most prevalent types of accidents. The mean attitude score of the women towards home accidents was 64.34 ± 15.03, and the mean total score of first aid knowledge was 27.14 ± 8.78. In our study, logistic regression analysis revealed that parents' employment status, having more than one child in the household, low-income level, and history of home accidents in the household increased the risk of experiencing home accidents for children. Conclusion It was determined that mothers' safety precautions and first aid practices were inadequate. Education, employment status, and income level were found to affect safety and first-aid attitudes towards home accidents. When our results are evaluated, it is recommended to organize training for mothers about home accidents, safety precautions, and first aid practices.

The present paper deals with the modelling of a Hall effect current sensor with open core magnetic concentrator. 3D magnetic field modelling is carried out using the finite element method (FEM) and Comsol Multiphysics software. Two rectangular core constructions are considered. Different geometric parameters of the magnetic concentrator are varied and their influence on the sensor characteristic is studied, with the aim of reducing the dependence on the output signal on the distance to the conductor. Of the studied parameters, core window length leads to the most significant change in the sensor characteristic. Future work can include the optimization of the sensor construction.

Background The study was conducted to determine the attitudes of women who were married at an early age in their region towards such marriages and their experiences related to pregnancies. Methods The data for the study were collected through the implementation of a semi-structured interview form, and the “deductive content analysis technique” was used to analyze the data. The study was conducted using a phenomenological design from qualitative research methods. Results Four main themes were obtained in the study. Theme 1 The process leading to early marriages: Women are married off with the decision of the family and the support of their relatives, and mostly without having met each other. Theme 2 The course of marriage: The first day of marriage is considered frightening, and the responsibilities of the house are burdened on a girl child. Theme 3 Pregnancies: Women report health problems due to the fact that they are still children themselves, and their bodies are not suitable for a pregnancy. Theme 4: Childcare: Women experience problems related to their inexperience and financial problems in caring for children, and at the same time, they do not want their children’s future to be like theirs. Theme 5: Cultural process leading to early marriages: Women state that early marriage is a traditional and cultural problem and that this situation is considered normal and should be. Conclusion The factors that influence the decision to enter into early marriage include family decisions and cultural norms. In addition to the challenges associated with marriage, women express a desire for their children to have access to more advantageous educational opportunities.

Purpose: This study aimed to compare the knowledge and health beliefs of women with and without an HPV diagnosis regarding the virus and its vaccine. Methods: Designed as a cross‐sectional case–control study, the research was conducted with 478 women attending a gynecology outpatient clinic in Istanbul. Data were collected using a sociodemographic questionnaire, the Human Papillomavirus Knowledge Scale (HPV‐KS), and the Health Belief Model Scale for HPV Infection and Vaccination (HPV‐HBMS). Results: The findings indicated that women diagnosed with HPV had significantly higher knowledge scores and a greater perceived seriousness of the infection compared to those without an HPV diagnosis ( p < 0.05), although overall knowledge levels remained low in both groups. A significant difference was also found between the two groups in terms of HPV vaccine awareness, Pap smear testing, and vaccination status. Logistic regression analysis revealed that higher education level, older age, a family history of cervical cancer, previous HPV vaccination, and having undergone Pap smear testing were associated with a reduced risk of HPV infection ( p < 0.05). Conclusion: These findings underline the importance of targeted education and outreach efforts to improve HPV awareness and vaccine uptake among women.

Olive oil production generates large volumes of solid and liquid waste with high organic load, acidity, and toxic phenolic compounds. Conventional disposal methods cause serious environmental problems such as groundwater contamination, greenhouse gas emissions, and inefficient use of resources. This study investigates a sustainable management approach for olive processing waste based on the zero discharge principle, integrating gasification and organic rankine cycle (ORC) systems for green energy production. The system operates with a biomass feed rate of 440 kg/h, produces 60 kg/h of biochar, and is powered by a thermal input of 2000 kWh th . The ORC unit operates at 15% electrical efficiency, generating 240 kW of electricity and 1360 kW of thermal energy. Mass and energy balance analyses show that nearly 100% of the waste can be converted into valuable outputs. Water recovery from olive mill wastewater was achieved through thermal evaporation. The biochar by-product can be utilized as a soil amendment or fuel additive. Economic feasibility analyses based on cost data demonstrate that profitability depends on electricity sale prices and the conversion of biochar into value-added products. A comparison of different biomass feedstocks reveals variability in cost but no significant difference in energy conversion efficiency. This research presents a viable, circular economy-oriented model for the olive oil industry in terms of sustainable waste valorization, water recovery, and renewable energy production.

To investigate the opinions of women residing in Turkey regarding abortion and its correlation with spirituality. A descriptive and cross-sectional study. The study included 487 women and data was collected between October and December 2023. The Descriptive Information Form, Stigmatizing Attitudes, Beliefs and Actions Scale (SABAS), and Spirituality Scale (SS) were used to evaluate the data and determine the correlation between them. Of the women surveyed, 78.6% reported no prior experience with curettage. The participants had low SABAS scores (26.95 ± 7.43) and high SS scores (22.50 ± 5.80). Age, education, employment status, religious affiliation, history of curettage, age at first childbirth, number of children, and number of siblings were all significantly correlated with SABAS and SS ( p  < 0.05). Additionally, a significant positive correlation was found between the participants’ SABAS total score and all sub-factor scores, as well as their SS total scores. It was also determined that as women’s stigmatization and negative attitudes towards curettage increased, their spiritual feelings increased as well ( p  < 0.05). A significant positive correlation was found between SS score and age and SABAS, and a negative correlation was found with the number of births ( p  < 0.05). It was found that women’s stigmatizing attitudes towards abortion were influenced by their spiritual beliefs. To prevent women from being caught between the consequences of unwanted pregnancies and their spiritual beliefs, it is important to meet their needs for family planning and health counseling.

Vascular-deposited IgG immune complexes promote neutrophil recruitment, but how this process is regulated is still unclear. Here we show that the CD18 integrin Mac-1, in its bent state, interacts with the IgG receptor FcγRIIA in cis to reduce the affinity of FcγRIIA for IgG and inhibit FcγRIIA-mediated neutrophil recruitment under flow. The Mac-1 rs1143679 lupus-risk variant reverses Mac-1 inhibition of FcγRIIA, as does a Mac-1 ligand and a mutation in Mac-1’s ligand binding αI-domain. Sialylated complex glycans on FcγRIIA interact with the αI-domain via divalent cations, and this interaction is required for FcγRIIA inhibition by Mac-1. Human neutrophils deficient in CD18 integrins exhibit augmented FcγRIIA-dependent recruitment to IgG-coated endothelium. In mice, CD18 integrins on neutrophils dampen IgG-mediated neutrophil accumulation in the kidney. In summary, cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 alters the threshold for IgG-mediated neutrophil recruitment. A disruption of this interaction may increase neutrophil influx in autoimmune diseases. Deposited immune complexes (IC) promote neutrophil recruitment, but the fine tuning of this process is still unclear. Here the authors show that the cis interaction of the IC receptor, FcγRIIA and CD18 integrin, Mac-1, on the neutrophil surface modulates neutrophil adhesion, with FcγRIIA sialylation specifically implicated in this interaction.

To evaluate and compare the analgesic effect of ultrasound-guided erector spinae plane (ESP) block with ultrasound-guided Quadratus Lumborum Block in pediatric lower abdominal surgeries. Randomized, prospective, double-blinded trial. Operating room and surgical ward. Sixty patients, aged 1 to 7 years with ASA scores of I-II scheduled for elective lower abdominal surgery were included in the study. Patients were randomized into two groups as ESPB group and QLB group. Ultrasound guided ESP block at L1 vertebral level was performed preoperatively using 0.5 ml/kg 0.25% bupivacaine (max 20 ml) to the patients in ESPB group. And ultrasound guided QLB block with transmuscular approach was performed preoperatively using 0.5 ml/kg 0.25% bupivacaine (max 20 ml) to the patients in QLB group. Face, Legs, Activity, Cry and Consolability (FLACC) scores for pain were recorded at 0, 1, 3 and 6 h postoperatively. Analgesic requirements and time to first analgesic requirement were also recorded. Fifty-seven patients were included in the final analyses. No significant difference was determined between the groups' FLACC scores at 0, 1, 3 or 6 h postoperatively (p > 0.05). No significant difference was also determined in times to first analgesia between the groups (p > 0.05). This study shows that the ESPB provides similar postoperative analgesia to the QLB in pediatric patients undergoing lower abdominal surgery. Clinicians could decide according to their clinical experiences. https://clinicaltrials.gov/ct2/show/NCT03463382. •Erector Spinae Plane Block is a novel technique for postoperative analgesia in many indications.•Quadratus Lumborum Block is a well known analgesic technique for different pediatric surgeries.•Erector Spinae Plane Block provides similar analgesia to Quadratus Lumborum Block for pediatric lower abdominal surgeries.•Opioid sparing effect could be achieved with both Quadratus Lumborum and Erector Spinae Plane blocks in pediatric surgeries.

Background Patients with intermediate and high-risk oropharyngeal cancer (OPC) have poorer response to standard treatment and poorer overall survival compared to low-risk OPC. CompARE is designed to test alternative approaches to intensified treatment for these patients to improve survival. Methods CompARE is a pragmatic phase III, open-label, multicenter randomised controlled trial with an adaptive multi-arm, multi-stage design and an integrated QuinteT Recruitment Intervention. Eligible OPC patients include those with human papillomavirus (HPV) negative, T1–T4, N1–N3 or T3–4, N0, or HPV positive N3, T4, or current smokers (or ≥ 10 pack years previous smoking history) with T1–T4, N2b–N3. CompARE was originally designed with four arms (one control [arm 1] and three experimental: arm 2—induction chemotherapy followed by arm 1; arm 3—dose-escalated radiotherapy plus concomitant cisplatin; and arm 4—resection of primary followed by arm 1). The three original experimental arms have been closed to recruitment and a further experimental arm opened (arm 5—induction durvalumab followed by arm 1 and then adjuvant durvalumab). Currently recruiting are arm 1 (control): standard treatment of 3-weekly cisplatin 100 mg/m 2 or weekly 40 mg/m 2 with intensity-modulated radiotherapy using 70 Gy in 35 fractions ± neck dissection determined by clinical and radiological assessment 3 months post-treatment, and arm 5 (intervention): one cycle of induction durvalumab 1500 mg followed by standard treatment then durvalumab 1500 mg every 4 weeks for a total of 6 months. The definitive and interim primary outcome measures are overall survival time and event-free survival (EFS) time, respectively. Secondary outcome measures include quality of life, toxicity, swallowing outcomes, feeding tube incidence, surgical complication rates, and cost-effectiveness. The design anticipates that after approximately 7 years, 84 required events will have occurred to enable analysis of the definitive primary outcome measure for this comparison. Planned interim futility analyses using EFS will also be performed. Discussion CompARE is designed to be efficient and cost-effective in response to new data, emerging new treatments or difficulties, with the aim of bringing new treatment options for these patients. Trial registration ISRCTN ISRCTN41478539 . Registered on 29 April 2015

Purpose This study aims to investigate the impact of spousal addiction on women's marital satisfaction and family peace in Turkey. Methods This hospital‐based case‐control study was conducted between May and September 2024 in a large city in Turkey. A total of 309 married women aged 18 years and older participated, including those married to men hospitalized for addiction and those married to non‐addicted men. Data were collected using self‐administered questionnaires covering socio‐demographic characteristics, addiction status, marital satisfaction, and the Family Peace Scale (FPS). Results The mean age of participants was 35.57 ± 9.58 years. Women whose husbands were undergoing addiction treatment (45.72 vs. 56.70) or addicted to any substance (49.13 vs. 59.11) had significantly lower FPS scores (p < 0.05). Similarly, FPS scores were significantly lower for women whose husbands were addicted to cigarettes (49.61 vs. 57.17), alcohol (44.17 vs. 54.59), drugs (44.52 vs. 56.39), or medication (41.27 vs. 53.61) (p < 0.05). According to the results of the logistic regression analysis, a higher educational level of the woman (OR = 2.388) was associated with a reduced likelihood of the man being addicted, whereas the presence of any substance addiction in the woman (OR = 2.422), lower FPS scores (OR = 2.042), and the presence of sexual problems (OR = 1.484) were associated with an increased likelihood. (p < 0.05). Conclusion This study shows that addictive behaviors harm marital satisfaction and family stability. In addition to addiction treatment, policymakers should enhance family support and preventive programs, while clinical practice should provide family therapy and communication and stress management interventions involving both individuals and their spouses. This study shows that addictive behaviors harm marital satisfaction and family stability. Family peace was worse for women whose husbands were addicted. Also, a higher educational level of the woman was associated with a reduced likelihood of the man being addicted, whereas the presence of any substance addiction in the woman, reduced family peace, and the presence of sexual problems were associated with an increased likelihood.