Explore the vast range of titles available.

Microrobots and nanorobots have been produced with various nature-inspired soft materials and operating mechanisms. However, freely operating a wirelessly miniaturized soft robot remains a challenge. In this study, a wireless crawling compact soft robot using induction heating was developed. The magnetic composite heater built into the robot was heated wirelessly via induction heating, causing a phase change in the working fluid surrounding the heater. The pressure generated from the evaporated fluid induces the bending of the robot, which is composed of elastomers. During one cycle of bending by heating and shrinking by cooling, the difference in the frictional force between the two legs of the robot causes it to move forward. This robot moved 7240 μm, representing 103% of its body length, over nine repetitions. Because the robot’s surface is made of biocompatible materials, it offers new possibilities for a soft exploratory microrobot that can be used inside a living body or in a narrow pipe.

Although digital solutions could mitigate the challenges faced by older adults living alone (OALA), only a few studies investigated the need for and acceptance of digital health interventions for self-management (DHISMs) among this demographic. Thus, we aim to explore this need and acceptance, along with the contextual factors, among OALA. A mixed-methods research approach was adopted. We conducted 1) a quantitative survey (n = 191) to investigate the need for and acceptance of DHISMs using a numeric rating scale and 2) a qualitative study (n = 24) based on focus group interviews to explore contextual factors related to the quantitative results. Qualitative data were analyzed using thematic analysis. In the quantitative study, the mean scores for the need for and acceptance of DHISMs were 6.41 and 6.53 out of 10, respectively. Emergency response systems had the highest need and acceptance scores, whereas digital interventions for behavioral change (medication adherence, sleep, stress, and diet management) had relatively lower scores. The qualitative analysis revealed two themes and five subthemes: the need for inclusive support for independent living (environmental safety and diverse self-management challenges with limited support) and multidimensional factors related to DHISM acceptance (personal, technological, and relational barriers and facilitators). In the future, the unique and multidimensional factors influencing the need for and acceptance of DHISMs among OALA should be carefully considered to support their self-management and independent living. Blended care, which involves integrating age-friendly technology with personalized human interaction, is pivotal for increasing DHISM acceptance in this population.

A modular soft actuator with snakeskin-inspired scales that generates an anisotropic friction force is designed and evaluated in this study. The actuator makes it possible to fabricate soft robots that can move on various surfaces in the natural environment. For existing modulus soft robots, additional connectors and several independent pneumatic pumps are required. However, we designed precise connection and snake-scale structures integrated with a single pneumatic modular actuator unit. The precise structure was printed using a DLP 3D printer. The movement characteristics of the soft robot changed according to the angle of the scale structure, and the movement distance increased as the number of modular soft actuator units increased. Soft robots that can move in operating environments such as flat land, tubes, inclined paths, and water have been realized. Furthermore, soft robots with modularization strategies can easily add modular units. We demonstrate the ability to deliver objects 2.5 times heavier than the full weight of the soft robot by adding tong-like structure to the soft robot. The development of a soft robot inspired by snakeskin suggests an easy approach to soft robots that enables various tasks even in environments where existing robots have limited activity.

Orthohantavirus hantanense (HTNV) poses a substantial global public health threat due to its role in causing hemorrhagic fever with renal syndrome (HFRS). HTNV outbreaks are particularly prevalent in the Gyeonggi and Gangwon Provinces of the Republic of Korea (ROK). This study aimed to evaluate the application of advanced nanopore sequencing and bioinformatics to generate complete genome sequences of HTNV, with the objective of accurately identifying infection sources and analyzing their genetic diversity. In 2022 and 2023, we collected 579 small mammals from 11 distinct locations across Gyeonggi and Gangwon Provinces, as well as in Gwangju Metropolitan City, ROK. Among these, 498 Apodemus agrarius specimens were subjected to an epidemiological survey to investigate HTNV infections. The serological and molecular positivity of HTNV were found to be 65/498 (13.1%) and 17/65 (26.2%), respectively. Furthermore, 15 whole-genome sequences of HTNV were obtained from rodents in Gyeonggi and Gangwon Provinces. We developed a novel amplicon-based nanopore sequencing approach to acquire high-fidelity and precise genomic sequences of HTNV. Genome exchange analysis revealed three reassortant candidates, including heterogeneous L segments, from Paju-si and Yeoncheon-gun in Gyeonggi Province. Our findings enhance the resolution of the spatiotemporal genomic surveillance of HTNV by consistently providing new viral sequences and epidemiological data from HFRS-endemic regions in the ROK. This report signifies a notable advancement in nanopore sequencing techniques and bioinformatics, offering a robust platform for genome-based diagnostics and sophisticated phylogenetic analyses of orthohantaviruses, which are essential for public health strategies aimed at controlling HFRS.

To receive a greater power and to demonstrate the soft bellows-shaped actuator’s wireless actuation, micro inductors were built for wireless power transfer and realized in a three-dimensional helical structure, which have previously been built in two-dimensional spiral structures. Although the three-dimensional helical inductor has the advantage of acquiring more magnetic flux linkage than the two-dimensional spiral inductor, the existing microfabrication technique produces a device on a two-dimensional plane, as it has a limit to building a complete three-dimensional structure. In this study, by using a three-dimensional printed soluble mold technique, a three-dimensional heater with helical coils, which have a larger heating area than a two-dimensional heater, was fabricated with three-dimensional receiving inductors for enhanced wireless power transfer. The three-dimensional heater connected to the three-dimensional helical inductor increased the temperature of the liquid and gas inside the bellows-shaped actuator while reaching 176.1% higher temperature than the heater connected to the two-dimensional spiral inductor. Thereby it enables a stroke of the actuator up to 522% longer than when it is connected to the spiral inductor. Therefore, three-dimensional micro coils can offer a significant approach to the development of wireless micro soft robots without incurring heavy and bulky parts such as batteries.

Orthohantaviruses cause hantavirus cardiopulmonary syndrome; most cases occur in the southwest region of the United States. We discuss a clinical case of orthohantavirus infection in a 65-year-old woman in Michigan and the phylogeographic link of partial viral fragments from the patient and rodents captured near the presumed site of infection.