Explore the vast range of titles available.

Background: Asymptomatic and mild form of the neurocognitive disorder in individuals with human immunodeficiency virus infection is still prevalent and a chief problem worldwide although the severity of the neurocognitive complications is decreasing after the introduction of combined highly active antiretroviral therapy. Aim: To study language and executive dysfunction of HIV patients in Clinical Stage 1 in an industrial scenario in Western Maharashtra as compared to healthy controls. Material and Methods: The Wisconsin card sorting test and Addenbrooke cognitive scale were done to check for executive function and language, respectively, and compared to age- and gender-matched HIV-negative controls. Results: Both the results of the WCST and Addenbrooke cognitive scale showed a decline in scores in the cases as compared to the controls overall. The distribution of cases as per the gender showed no significant difference, whereas there was a significant difference as per the age. Conclusion: In asymptomatic HIV patients, there is a decline in executive function and language as compared to the healthy controls. As most of the individuals were employed, there is a need to assess their neurocognitive function regularly as the progress of the illness can be monitored and cognitive training can be advised in these HIV-positive patients, which will not only benefit the individuals but the industrial sector in the long run as well.

Clinical features of schizophrenia and cannabis-induced psychosis (CIP) share many overlapping characteristics. We present a case of Cannabis Dependence Syndrome, whose first presentation was with first-rank symptoms of schizophrenia in the form of thought insertion, withdrawal and delusion of control.

Background: Internet gaming disorder (IGD) is an entity of clinical attention prominent among schoolgoing students. The reported nature and extent of Internet gaming varies widely, as does the extent of its effects. Aim: This study aimed to assess the prevalence of IGD and factors associated with it. Methods: After institution ethics approval, individual assent, and parental consent, a cross-sectional study was conducted among 142 students of a school in western Maharashtra. A specially designed sociodemographic pro forma and IGD Scale were administered to the students. Data thus generated were statistically analyzed and compared with published literature. Results: The prevalence of IGD was 10.6% among 13-19-year-old students. It was significantly higher among male students (15.3%) than female students (3.5%). Multivariate logistic regression found IGD to be significantly associated with male gender and lower age at first gameplay. Conclusions: IGD affects a tenth of our schoolgoing population with a male preponderance. Lower age at first gameplay had an adverse association.

Asymptomatic and mild form of the neurocognitive disorder in individuals with human immunodeficiency virus infection is still prevalent and a chief problem worldwide although the severity of the neurocognitive complications is decreasing after the introduction of combined highly active antiretroviral therapy. To study language and executive dysfunction of HIV patients in Clinical Stage 1 in an industrial scenario in Western Maharashtra as compared to healthy controls. The Wisconsin card sorting test and Addenbrooke cognitive scale were done to check for executive function and language, respectively, and compared to age- and gender-matched HIV-negative controls. Both the results of the WCST and Addenbrooke cognitive scale showed a decline in scores in the cases as compared to the controls overall. The distribution of cases as per the gender showed no significant difference, whereas there was a significant difference as per the age. In asymptomatic HIV patients, there is a decline in executive function and language as compared to the healthy controls. As most of the individuals were employed, there is a need to assess their neurocognitive function regularly as the progress of the illness can be monitored and cognitive training can be advised in these HIV-positive patients, which will not only benefit the individuals but the industrial sector in the long run as well.

Fibrillary glomerulonephritis (FGN) is a rare and complex renal disease where the accumulation of non-amyloid microfibrils composed of polyclonal immunoglobulin G within the mesangium and glomerular capillaries results in structural and functional abnormalities in the kidney's filtering units. The direct link between FGN and cardiomyopathy is not well established. However, it may be caused secondarily by systemic inflammation, uremia, or other overlapping factors and comorbidities. In our case, it was believed to be significantly influenced and worsened by various comorbid conditions, with hypertension being the most common cardiovascular risk factor in FGN itself, contributing to structural and functional cardiac impairment, including left ventricular hypertrophy and systolic dysfunction, rather than direct myocardial infiltration or damage by fibrillary deposit. We have a case of a 60-year-old female who presented with a severe manifestation of FGN, associated with secondary cardiomyopathy and renal failure complications, including hypertension-related issues, nephrotic syndrome with significant proteinuria, peripheral edema, anasarca, and shortness of breath, initially leading to hospitalization. Her renal insufficiency subsequently progressed to end-stage renal disease, and the discovery of a nephrotic range of proteinuria led to a kidney biopsy, confirming the diagnosis of FGN. Her renal recovery remained poor due to persistent volume overload, which impeded renal recovery and which required the initiation of dialysis. The patient experienced a rare cardiac involvement related to underlying FGN, which could not be confirmed through a cardiac biopsy because she chose to refuse this invasive test.  The treatment with prednisone and rituximab targeted FGN, reducing proteinuria and improving renal function, which allowed for a decrease in hemodialysis and normalization of the erythrocyte sedimentation rate and C-reactive protein at 12 months. Cardiac function also improved after six months, with lower brain natriuretic peptide levels, increased left ventricular ejection fraction (LVEF), and reversal of ventricular remodeling on echocardiogram, suggesting that early immunologic intervention can reverse cardiomyopathy and prevent progression. Longer follow-up is recommended, as improved LVEF is associated with a better prognosis in heart failure. FGN typically affects the kidneys, making cardiac issues uncommon. Therefore, further research is needed to understand the prevalence and mechanisms of cardiac involvement in FGN for developing targeted therapies.