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Neuroimaging, in particular magnetic resonance imaging (MRI), has been playing an important role in understanding brain functionalities and its disorders during the last couple of decades. These cutting-edge MRI scans, supported by high-performance computational tools and novel ML techniques, have opened up possibilities to unprecedentedly identify neurological disorders. However, similarities in disease phenotypes make it very difficult to detect such disorders accurately from the acquired neuroimaging data. This article critically examines and compares performances of the existing deep learning (DL)-based methods to detect neurological disorders—focusing on Alzheimer’s disease, Parkinson’s disease and schizophrenia—from MRI data acquired using different modalities including functional and structural MRI. The comparative performance analysis of various DL architectures across different disorders and imaging modalities suggests that the Convolutional Neural Network outperforms other methods in detecting neurological disorders. Towards the end, a number of current research challenges are indicated and some possible future research directions are provided.

Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Categorized in three broad types (i.e. images, signals, and sequences), these data are huge in amount and complex in nature. Mining such enormous amount of data for pattern recognition is a big challenge and requires sophisticated data-intensive machine learning techniques. Artificial neural network-based learning systems are well known for their pattern recognition capabilities, and lately their deep architectures—known as deep learning (DL)—have been successfully applied to solve many complex pattern recognition problems. To investigate how DL—especially its different architectures—has contributed and been utilized in the mining of biological data pertaining to those three types, a meta-analysis has been performed and the resulting resources have been critically analysed. Focusing on the use of DL to analyse patterns in data from diverse biological domains, this work investigates different DL architectures’ applications to these data. This is followed by an exploration of available open access data sources pertaining to the three data types along with popular open-source DL tools applicable to these data. Also, comparative investigations of these tools from qualitative, quantitative, and benchmarking perspectives are provided. Finally, some open research challenges in using DL to mine biological data are outlined and a number of possible future perspectives are put forward.

According to the World Health Organization (WHO), dementia is the seventh leading reason of death among all illnesses and one of the leading causes of disability among the world's elderly people. Day by day the number of Alzheimer's patients is rising. Considering the increasing rate and the dangers, Alzheimer's disease should be diagnosed carefully. Machine learning is a potential technique for Alzheimer's diagnosis but general users do not trust machine learning models due to the black-box nature. Even, some of those models do not provide the best performance because of using only neuroimaging data. To solve these issues, this paper proposes a novel explainable Alzheimer's disease prediction model using a multimodal dataset. This approach performs a data-level fusion using clinical data, MRI segmentation data, and psychological data. However, currently, there is very little understanding of multimodal five-class classification of Alzheimer's disease. For predicting five class classifications, 9 most popular Machine Learning models are used. These models are Random Forest (RF), Logistic Regression (LR), Decision Tree (DT), Multi-Layer Perceptron (MLP), K-Nearest Neighbor (KNN), Gradient Boosting (GB), Adaptive Boosting (AdaB), Support Vector Machine (SVM), and Naive Bayes (NB). Among these models RF has scored the highest value. Besides for explainability, SHapley Additive exPlanation (SHAP) is used in this research work. The performance evaluation demonstrates that the RF classifier has a 10-fold cross-validation accuracy of 98.81% for predicting Alzheimer's disease, cognitively normal, non-Alzheimer's dementia, uncertain dementia, and others. In addition, the study utilized Explainable Artificial Intelligence based on the SHAP model and analyzed the causes of prediction. To the best of our knowledge, we are the first to present this multimodal (Clinical, Psychological, and MRI segmentation data) five-class classification of Alzheimer's disease using Open Access Series of Imaging Studies (OASIS-3) dataset. Besides, a novel Alzheimer's patient management architecture is also proposed in this work.

The Internet of Things (IoT) uses wireless networks without infrastructure to install a huge number of wireless sensors that track system, physical, and environmental factors. There are a variety of WSN uses, and some well-known application factors include energy consumption and lifespan duration for routing purposes. The sensors have detecting, processing, and communication capabilities. In this paper, an intelligent healthcare system is proposed which consists of nano sensors that collect real-time health status and transfer it to the doctor’s server. Time consumption and various attacks are major concerns, and some existing techniques contain stumbling blocks. Therefore, in this research, a genetic-based encryption method is advocated to protect data transmitted over a wireless channel using sensors to avoid an uncomfortable data transmission environment. An authentication procedure is also proposed for legitimate users to access the data channel. Results show that the proposed algorithm is lightweight and energy efficient, and time consumption is 90% lower with a higher security ratio.

The integration of cutting-edge technologies such as the Internet of Things (IoT), robotics, and machine learning (ML) has the potential to significantly enhance the productivity and profitability of traditional fish farming. Farmers using traditional fish farming methods incur enormous economic costs owing to labor-intensive schedule monitoring and care, illnesses, and sudden fish deaths. Another ongoing issue is automated fish species recommendation based on water quality. On the one hand, the effective monitoring of abrupt changes in water quality may minimize the daily operating costs and boost fish productivity, while an accurate automatic fish recommender may aid the farmer in selecting profitable fish species for farming. In this paper, we present AquaBot, an IoT-based system that can automatically collect, monitor, and evaluate the water quality and recommend appropriate fish to farm depending on the values of various water quality indicators. A mobile robot has been designed to collect parameter values such as the pH, temperature, and turbidity from all around the pond. To facilitate monitoring, we have developed web and mobile interfaces. For the analysis and recommendation of suitable fish based on water quality, we have trained and tested several ML algorithms, such as the proposed custom ensemble model, random forest (RF), support vector machine (SVM), decision tree (DT), K-nearest neighbor (KNN), logistic regression (LR), bagging, boosting, and stacking, on a real-time pond water dataset. The dataset has been preprocessed with feature scaling and dataset balancing. We have evaluated the algorithms based on several performance metrics. In our experiment, our proposed ensemble model has delivered the best result, with 94% accuracy, 94% precision, 94% recall, a 94% F1-score, 93% MCC, and the best AUC score for multi-class classification. Finally, we have deployed the best-performing model in a web interface to provide cultivators with recommendations for suitable fish farming. Our proposed system is projected to not only boost production and save money but also reduce the time and intensity of the producer’s manual labor.

Breast cancer is the most prevailing cancer in the world and each year affecting millions of women. It is also the cause of largest number of deaths in women dying in cancers. During the last few years, researchers are proposing different convolutional neural network models in order to facilitate diagnostic process of breast cancer. Convolutional neural networks are showing promising results to classify cancers using image datasets. There is still a lack of standard models which can claim the best model because of unavailability of large datasets that can be used for models’ training and validation. Hence, researchers are now focusing on leveraging the transfer learning approach using pre-trained models as feature extractors that are trained over millions of different images. With this motivation, this paper considers eight different fine-tuned pre-trained models to observe how these models classify breast cancers applying on ultrasound images. We also propose a shallow custom convolutional neural network that outperforms the pre-trained models with respect to different performance metrics. The proposed model shows 100% accuracy and achieves 1.0 AUC score, whereas the best pre-trained model shows 92% accuracy and 0.972 AUC score. In order to avoid biasness, the model is trained using the fivefold cross validation technique. Moreover, the model is faster in training than the pre-trained models and requires a small number of trainable parameters. The Grad-CAM heat map visualization technique also shows how perfectly the proposed model extracts important features to classify breast cancers.

The sixth-generation (6G) wireless communication network is expected to integrate the terrestrial, aerial, and maritime communications into a robust network which would be more reliable, fast, and can support a massive number of devices with ultra-low latency requirements. The researchers around the globe are proposing cutting edge technologies such as artificial intelligence (AI)/machine learning (ML), quantum communication/quantum machine learning (QML), blockchain, tera-Hertz and millimeter waves communication, tactile Internet, non-orthogonal multiple access (NOMA), small cells communication, fog/edge computing, etc., as the key technologies in the realization of beyond 5G (B5G) and 6G communications. In this article, we provide a detailed overview of the 6G network dimensions with air interface and associated potential technologies. More specifically, we highlight the use cases and applications of the proposed 6G networks in various dimensions. Furthermore, we also discuss the key performance indicators (KPI) for the B5G/6G network, challenges, and future research opportunities in this domain.

Smart, interactive healthcare is necessary in the modern age. Several issues, such as accurate diagnosis, low-cost modeling, low-complexity design, seamless transmission, and sufficient storage, should be addressed while developing a complete healthcare framework. In this paper, we propose a patient state recognition system for the healthcare framework. We design the system in such a way that it provides good recognition accuracy, provides low-cost modeling, and is scalable. The system takes two main types of input, video and audio, which are captured in a multi-sensory environment. Speech and video input are processed separately during feature extraction and modeling; these two input modalities are merged at score level, where the scores are obtained from the models of different patients’ states. For the experiments, 100 people were recruited to mimic a patient’s states of normal, pain, and tensed. The experimental results show that the proposed system can achieve an average 98.2 % recognition accuracy.

Over the last decade, mobile health applications (mHealth App) have evolved exponentially to assess and support our health and well-being. This paper presents an Artificial Intelligence (AI)-enabled mHealth app rating tool, called ACCU3RATE, which takes multidimensional measures such as user star rating, user review and features declared by the developer to generate the rating of an app. However, currently, there is very little conceptual understanding on how user reviews affect app rating from a multi-dimensional perspective. This study applies AI-based text mining technique to develop more comprehensive understanding of user feedback based on several important factors, determining the mHealth app ratings. Based on the literature, six variables were identified that influence the mHealth app rating scale. These factors are user star rating, user text review, user interface (UI) design, functionality, security and privacy, and clinical approval. Natural Language Toolkit package is used for interpreting text and to identify the App users' sentiment. Additional considerations were accessibility, protection and privacy, UI design for people living with physical disability. Moreover, the details of clinical approval, if exists, were taken from the developer's statement. Finally, we fused all the inputs using fuzzy logic to calculate the new app rating score. ACCU3RATE concentrates on heart related Apps found in the play store and App gallery. The findings indicate the efficacy of the proposed method as opposed to the current device scale. This study has implications for both App developers and consumers who are using mHealth Apps to monitor and track their health. The performance evaluation shows that the proposed mHealth scale has shown excellent reliability as well as internal consistency of the scale, and high inter-rater reliability index. It has also been noticed that the fuzzy based rating scale, as in ACCU3RATE, matches more closely to the rating performed by experts.

A novel strain of Coronavirus, identified as the Severe Acute Respiratory Syndrome-2 (SARS-CoV-2), outbroke in December 2019 causing the novel Corona Virus Disease (COVID-19). Since its emergence, the virus has spread rapidly and has been declared a global pandemic. As of the end of January 2021, there are almost 100 million cases worldwide with over 2 million confirmed deaths. Widespread testing is essential to reduce further spread of the disease, but due to a shortage of testing kits and limited supply, alternative testing methods are being evaluated. Recently researchers have found that chest X-Ray (CXR) images provide salient information about COVID-19. An intelligent system can help the radiologists to detect COVID-19 from these CXR images which can come in handy at remote locations in many developing nations. In this work, we propose a pipeline that uses CXR images to detect COVID-19 infection. The features from the CXR images were extracted and the relevant features were then selected using Hybrid Social Group Optimization algorithm. The selected features were then used to classify the CXR images using a number of classifiers. The proposed pipeline achieves a classification accuracy of 99.65% using support vector classifier, which outperforms other state-of-the-art deep learning algorithms for binary and multi-class classification.