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Background In China, Internet-Based Sharing Nursing Service (IBSNS) is a new mode of nursing service delivery that has been in practice for over five years, which enables nurses to provide care at clients’ home. However, the acceptance and associated factors of IBSNS among caregivers of elderly with chronic diseases who are the major clients of the service were unclear. Aim To explore the acceptance of IBSNS and its associated factors among Chinese caregivers of elderly patient with chronic diseases based on the modified Technology Acceptance Model (mTAM). Methods A cross-sectional study was conducted from February 2023 to March 2023. Caregivers of hospitalized elderly with chronic diseases were recruited using convenience sampling method from three hospitals in Beijing, China. Data were obtained from self-reports of participants. Structural equation modeling was used to analyze data. Results A total of 65.1% of the caregivers had neutral to weakly positive behavioral intention of IBSNS use. The mTAM model was supported with good model fit. Perceived ease of use was positively associated with perceived usefulness. Both perceived usefulness and perceived security were positively associated with attitude, consequently, attitude was associated with behavioral intention. Conclusions Improving the ease of use, security, and usefulness may be helpful to increase the positive attitude towards IBSNS and behavioral intention of using IBSNS, which provides valuable insights that can help healthcare providers improve the integration of technology in patient care, ultimately leading to better health outcomes and more efficient healthcare systems.

This article describes the 2023 IEEE Low-Power Computer Vision Challenge (LPCVC). Since 2015, LPCVC has been an international competition devoted to tackling the challenge of computer vision (CV) on edge devices. Most CV researchers focus on improving accuracy, at the expense of ever-growing sizes of machine models. LPCVC balances accuracy with resource requirements. Winners must achieve high accuracy with short execution time when their CV solutions run on an embedded device, such as Raspberry PI or Nvidia Jetson Nano. The vision problem for 2023 LPCVC is segmentation of images acquired by Unmanned Aerial Vehicles (UAVs, also called drones) after disasters. The 2023 LPCVC attracted 60 international teams that submitted 676 solutions during the submission window of one month. This article explains the setup of the competition and highlights the winners' methods that improve accuracy and shorten execution time.

Comparative analysis based on the mitogenomes of hares in Xinjiang, China, is limited. In this study, the complete mitochondrial genomes of seven hare samples including four hare species and their hybrids from different environments were sequenced, assembled, and annotated. Subsequently, we performed base content and bias analysis, tRNA analysis, phylogenetic analysis, and amino acid sequence analysis of the annotated genes to understand their characteristics and phylogenetic relationship. Their mitogenomes are circular molecules (from 16,691 to 17,598 bp) containing 13 protein-coding genes, two rRNA genes, 22 tRNA genes, and a control region, which are similar with other Lepus spp. worldwide. The relative synonymous codon usage analysis revealed that the adaptation of Lepus yarkandensis to its unique arid and hot environment might be associated with synthesizing amino acids like alanine, leucine, serine, arginine, and isoleucine and the terminator caused by the different usage of codons. Further, we utilized the MEME model and identified two positive selection genes (ND4, ND5) in Lepus tibetanus pamirensis and one (ND5) in L. yarkandensis that might be important to their adaptation to the plateau and dry and hot basin environments, respectively. Meanwhile, Lepus tolai lehmanni and Lepus timidus may have evolved different adaptive mechanisms for the same cold environment. This study explored the evolutionary dynamics of Xinjiang hares’ mitochondrial genomes, providing significant support for future research into their adaptation mechanisms in extreme environments.

Rammed earth (RE) dwellings are characterized by accessible materials, low cost, and environmental sustainability. However, their poor seismic resistance limits their application. To address this issue, three conventional technical approaches have been developed: (1) adding cement to improve strength; (2) improving structural integrity using reinforced concrete ring beams and columns; and (3) embedding vertical steel bars in order to provide resistance against horizontal seismic actions. While effective, these methods rely on energy-intensive materials with high carbon emissions. In this study, we analyze the seismic damage characteristics and construction mechanisms of RE walls. The results reveal that the horizontal joints in RE walls significantly weaken their resistance to horizontal seismic actions. To mitigate this, three types of undulating joints are proposed and six specimens tested. The maximum horizontal loads of the specimens with local subsidence-type joints are 132.44 kN and 135.41 kN, respectively, which are approximately 50% higher than specimens with horizontal joints, whose maximum horizontal loads are 80.7 kN and 85.83 kN, respectively, while the maximum horizontal loads of the specimens with horizontally concatenated gentle arc-type joints are 151.17 kN and 173.58 kN, respectively, and they exhibit nearly double the shear capacity of the specimens with horizontal joints. Building on these findings and test results, we also include recommendations for integrating elegant RE wall texture design with seismic-resistant undulating joint technology.

Open-3DSIM is an open-source reconstruction platform for three-dimensional structured illumination microscopy. We demonstrate its superior performance for artifact suppression and high-fidelity reconstruction relative to other algorithms on various specimens and over a range of signal-to-noise levels. Open-3DSIM also offers the capacity to extract dipole orientation, paving a new avenue for interpreting subcellular structures in six dimensions ( xyzθλt ). The platform is available as MATLAB code, a Fiji plugin and an Exe application to maximize user-friendliness. Open-3DSIM is a versatile open-source software for high-fidelity reconstruction of three-dimensional structured illumination microscopy data (with polarization). It is available in three convenient forms for user-friendly and customizable applications.

Manipulating liquid flow over open solid substrate at nanoscale is important for printing, sensing, and energy devices. The predominant methods of liquid maneuvering usually involve complicated surface fabrications, while recent attempts employing external stimuli face difficulties in attaining nanoscale flow control. Here we report a largely unexplored ion beam induced film wetting (IBFW) technology for open surface nanofluidics. Local electrostatic forces, which are generated by the unique charging effect of Helium focused ion beam (HFIB), induce precursor film of ionic liquid and the disjoining pressure propels and stabilizes the nanofilm with desired patterns. The IBFW technique eliminates the complicated surface fabrication procedures to achieve nanoscale flow in a controllable and rewritable manner. By combining with electrochemical deposition, various solid materials with desired patterns can be produced. With a helium focused ion beam, an ionic liquid can undergo induced wetting to flow into a desired pattern on a surface in a controllable, rewriteable manner. Combined with electrochemical deposition, patterned solid materials can be produced.

Gut microbiota plays a key role in the development of sarcopenia via the 'gut-muscle' axis, and probiotics-based therapy might be a strategy for sarcopenia. Fecal microbiota transplantation from young donors (yFMT) has attracted much attention because of its probiotic function. However, whether or not yFMT is effective for sarcopenia in old recipients is largely unknown. Thus, we aimed to investigate the effect and mechanism of yFMT on age-related sarcopenia. The fecal microbiota of either young (12 weeks) or old (88 weeks) donor rats was transplanted into aged recipient rats for 8 weeks. Then, muscle mass, muscle strength, muscle function, muscle atrophy, and muscle regeneration capacity were measured. Analysis of fecal 16 s rRNA, serum non-targeted metabolomic, gut barrier integrity, and muscle transcriptome was conducted to elucidate the interaction between gut microbiota and skeletal muscles. As evaluated by magnetic resonance imaging examination, grip strength test (P < 0.01), rotarod test (P < 0.05), and exhaustive running test (P < 0.05), we found that yFMT mitigated muscle mass loss, muscle strength weakness, and muscle function impairment in aged rats. yFMT also countered age-related atrophy and poor regeneration capacity in fast- and slow-switch muscles, which were manifested by the decrease in slow-switch myofibres (both P < 0.01) and muscle interstitial fibrosis (both P < 0.05) and the increase in the cross-section area of myofibres (both P < 0.001), fast-switch myofibres (both P < 0.01), and muscle satellite cells (both P < 0.001). In addition, yFMT ameliorated age-related dysbiosis of gut microbiota and metabolites by promoting the production of beneficial bacteria and metabolites-Akkermansia, Lactococcus, Lactobacillus, γ-glutamyltyrosine, 3R-hydroxy-butanoic acid, and methoxyacetic acid and inhibiting the production of deleterious bacteria and metabolites-Family_XIII_AD3011_group, Collinsella, indoxyl sulfate, indole-3-carboxilic acid-O-sulphate, and trimethylamine N-oxide. Also, yFMT prevented age-related destruction of gut barrier integrity by increasing the density of goblet cells (P < 0.0001) and the expression levels of mucin-2 (P < 0.0001) and tight junctional proteins (all P < 0.05). Meanwhile, yFMT attenuated age-related impairment of mitochondrial biogenesis and function in fast- and slow-switch muscles. Correlation analysis revealed that yFMT-induced alterations of gut microbiota and metabolites might be closely related to mitochondria-related genes and sarcopenia-related phenotypes. yFMT could reshape the dysbiosis of gut microbiota and metabolites, maintain gut barrier integrity, and improve muscle mitochondrial dysfunction, eventually alleviating sarcopenia in aged rats. yFMT might be a new therapeutic strategy for age-related sarcopenia.

Recently, near-net-shape rolling has emerged as a key manufacturing technology for producing high-precision, fatigue-resistant bearing rings with irregular cross-sections, particularly for the production of Wind Turbine Shaft Bearings (WTSBs). The deformation behavior of the material during this rolling process is governed by temperature and rolling speed. Therefore, based on a thermomechanical coupled analysis, a simulation model for the deformation process of GCr15SiMn profiled rings during variable-speed rolling was developed in this study. The model was experimentally validated, confirming a dimensional error of less than 3‰. And then, the distribution of strain and temperature were analyzed during the rolling of the profiled ring. As the initial temperature increased from 1040 °C to 1160 °C, the standard deviation of strain (SDP) decreased from 6.12 to 4.05. Correspondingly, the standard deviation of temperature (SDT) was raised from 4.32 to 4.74. When the drive roll speed was increased from 2.5 rad/s to 4.0 rad/s, the SDP was reduced from 4.24 to 3.42. In addition, the SDT decreased from 4.42 to 3.21. The research indicates that SDP is primarily affected by initial temperature, whereas SDT is significantly influenced by drive roller speed. On the one hand, this study provides a clearly defined optimization framework, parameter ranges for achieving optimal uniformity in GCr15SiMn material (temperature of 1100–1130 °C, speed of 3.0–3.5 rad/s), and their anticipated benefits (an SDP reduction of 32% and an SDT reduction of 15%). On the other hand, it also establishes quantifiable industrial control targets, defining key quality assurance values (SDP ≤ 5.0, SDT ≤ 4.5). The rolling stability and precision can be improved through the selection of optimized rolling temperatures and speeds. This finding provides a theoretical foundation and technical framework for improving the rolling process stability of profiled cross-section bearing rings. Furthermore, this study is of positive significance for reducing the manufacturing costs of high-performance WTSBs.

Transgender women (TGW) worldwide report disproportionate violence victimization, depression and condomless anal intercourse (CAI), but the mechanism of the coexistence remains unclear. Using snowball sampling, we recruited 198 self-identified TGW in Shenyang, China between April 2017 and July 2017, and conducted confidential questionnaire survey among them. Positive HIV status was reported by 49 (24.7%) participants. 117 (59.1%) reported at least one type of lifetime violence victimization, with transactional sexual partners being the main violence perpetrators. 108 (54.5%) reported mild to severe depression. 105 (53.0%) reported having CAI with their sexual partners during the last 6 months. Path analysis showed that the association between participants’ violence victimization and CAI was fully mediated by their depression (indirect effect: 0.083, p = 0.014; direct effect: 0.137, p = 0.121). We suggest to incorporate violence screening and prevention and mental health services into intervention strategies to prevent CAI among Chinese TGW.