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Jack Veeder is dying. Soon. And that impending event brings his son Jimmy back to the Imperial Valley of southern California just north of the Calexico/Mexicali border. Jimmy hopes he can spend what time his father has left laughing and reminiscing. But Jack's got one dying request. He needs Jimmy to find a Mexican prostitute named Yolanda. Enlisting the help of his boyhood friend Bobby Maves, the pair stumbles through the violent, the exploited, and the corrupted of Mexicali. It doesn't take long before they're in over their heads. And as Jimmy tries to survive the dangers of the Mexicali underworld, he unwittingly uncovers truths about his father he never imagined, forcing Jimmy to come to terms with the man he thought he knew, and to decide just what sort of man he wants to become.

Issues associated with population control in the People's Republic of China, including its one-child policy, adopted in 1979, have generally been approached from two points of view. One, adopted by the PRC government and connected with Malthusian or neo-Malthusian economic theory, links a country's economic development to an appropriate population size and economic degradation to overpopulation. A second point of view, largely critical, deals with policy enforcement as yet another example of state-sanctioned coercion of individual behavior in a Marxist-Leninist state. But another dynamic operates in the PRC as well: the complex interplay of public-policy administrative practices, institutional structures, and guidelines for policy implementation connected to cultural and political attributes unique to Mainland China. Accordingly, this study examines the relevance of principles that guide official PRC policy articulations—notably the political ideology of the Chinese Communist Party—to shaping the administrative perspective of one-child-policy implementation, including problems and challenges posed by enforcement protocols. Those guiding principles are also relevant to policy-implementation consequences both perceived and directly experienced by those who have been and are obliged to comply with the policy. Relying in particular on input from persons in the city of Hefei, Anhui Province, who have had administrative and lay experience of the policy over the course of its history, the study identifies linkages between achievements and problems of one-child policy on one hand, and the engine of policy compliance, including the variety of social and political controls embedded in implementation, on the other.

There's gold in them thar hills or more precisely, in Arizona's Chocolate Mountains, where one hundred years ago a miner stashed a king's ransom of the stuff. But times have changed. The world has changed. And now the Chocolate Mountains are the home of the largest military artillery range in the world. Harry's living on disability and getting liquored up and beaten down. Frank's a feisty old-timer battling cancer and a domineering daughter. And Ricky's a good kid in a bad spot, doing everything for family. Together they're staking what little they have left on a dangerous quest to the Big Maria Mine and the gold that can offer them a new beginning. Unfortunately a meth-dealing biker wants a piece, a trigger-happy AWOL soldier wants to play chicken in a live minefield, two stubborn burros want to go home, a starving mountain lion wants his dinner, and the US Army wants to rain on our heroes parade with real bombs. When you're all out of crazy ideas, you've got to try the stupid ones.

What does the FCC need to hear from us next Monday in Memphis? It needs to help all communities develop programs that will integrate high speed internet access programs into education, health care and economic development programs in our communities. This hearing is a good first step. The FCC must make adoption and use of the Internet for all Americans its highest priority. As it does so, the FCC should resist any regulatory policies that might impede the goal of 100% access. I echo the concerns raised by the major national civil rights organizations in the Internet regulation (sometimes called \"net neutrality\") rulemaking proceeding and ask that the FCC answer all questions raised to ensure that the regulatory rules do not hinder the President's goal of 100% broadband adoption and use. I'm excited for Memphis on the eve of the FCC's field hearing. The commissioners' willingness to get out of Washington and speak to people who most need digital empowerment is a progressive step in the right direction of broadband equality.

Across the South, women of color are 26 times more likely to be HIV-positive than white women, and while African Americans make up 19 percent of the South's population they account for over 60 percent of all new cases.

DNA sequence information underpins genetic research, enabling discoveries of important biological or medical benefit. Sequencing projects have traditionally used long (400–800 base pair) reads, but the existence of reference sequences for the human and many other genomes makes it possible to develop new, fast approaches to re-sequencing, whereby shorter reads are compared to a reference to identify intraspecies genetic variation. Here we report an approach that generates several billion bases of accurate nucleotide sequence per experiment at low cost. Single molecules of DNA are attached to a flat surface, amplified in situ and used as templates for synthetic sequencing with fluorescent reversible terminator deoxyribonucleotides. Images of the surface are analysed to generate high-quality sequence. We demonstrate application of this approach to human genome sequencing on flow-sorted X chromosomes and then scale the approach to determine the genome sequence of a male Yoruba from Ibadan, Nigeria. We build an accurate consensus sequence from >30× average depth of paired 35-base reads. We characterize four million single-nucleotide polymorphisms and four hundred thousand structural variants, many of which were previously unknown. Our approach is effective for accurate, rapid and economical whole-genome re-sequencing and many other biomedical applications. Ethnic variation in the genes The power of the latest massively parallel synthetic DNA sequencing technologies is demonstrated in two major collaborations that shed light on the nature of genomic variation with ethnicity. The first describes the genomic characterization of an individual from the Yoruba ethnic group of west Africa. The second reports a personal genome of a Han Chinese, the group comprising 30% of the world's population. These new resources can now be used in conjunction with the Venter, Watson and NIH reference sequences. A separate study looked at genetic ethnicity on the continental scale, based on data from 1,387 individuals from more than 30 European countries. Overall there was little genetic variation between countries, but the differences that do exist correspond closely to the geographic map. Statistical analysis of the genome data places 50% of the individuals within 310 km of their reported origin. As well as its relevance for testing genetic ancestry, this work has implications for evaluating genome-wide association studies that link genes with diseases.

Increasing prevalence of mental health disorders within the Australian population is a serious public health issue. Adequate intake of fruits and vegetables (FV), dietary fibre (DF) and resistant starch (RS) is associated with better mental and physical health. Few longitudinal studies exist exploring the temporal relationship. Using a validated food frequency questionnaire, we examined baseline FV intakes of 5845 Australian adults from the AusDiab study and estimated food group-derived DF and RS using data from the literature. Perceived mental health was assessed at baseline and 5 year follow up using SF-36 mental component summary scores (MCS). We conducted baseline cross-sectional analysis and prospective analysis of baseline dietary intake with perceived mental health at 5 years. Higher baseline FV and FV-derived DF and RS intakes were associated with better 5 year MCS (p < 0.001). A higher FV intake (754 g/d vs. 251 g/d, Q4 vs. Q1) at baseline had 41% lower odds (OR = 0.59: 95% CI 0.46–0.75) of MCS below population average (<47) at 5 year follow up. Findings were similar for FV-derived DF and RS. An inverse association was observed with discretionary food-derived DF and RS. This demonstrates the association between higher intakes of FV and FV-derived DF and RS with better 5 year mental health outcomes. Further RCTs are necessary to understand mechanisms that underlie this association including elucidation of causal effects.

I am sick and tired of the race baiting and bigotry surrounding the efforts to change the Georgia state flag. Don't confuse African- Americans' discomfort with the Confederate symbol as an attack on the \"South.\" Most African-Americans understand and respect feelings of pride and heritage surrounding the memory of those who died for the Confederacy. For most African-Americans, however, the Confederate symbol is equivalent to the swastika. The symbol was so embraced by those with violent hatred toward African-Americans that it becomes impossible for us to separate the good history from the bad history when we see the St. Andrew's cross with stars. It is a constant reminder that many African-Americans suffered or died needlessly at the hands of people cloaked in the Confederate symbol.