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"Shaw, Marc"
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Plasmodium knowlesi in a traveller returning to New Zealand
The recent discovery that
Plasmodium knowlesi causes malaria in human populations, established it as the fifth species of plasmodium that may do so. A case of
P. knowlesi malaria is described in a helicopter pilot from New Zealand, who became ill after returning from recurring visits to Malaysian Borneo in June 2010. His
P. knowlesi infection was not detected using microscopic examination and a rapid diagnostic test for malaria, but was confirmed by both PCR (polymerase chain reaction) and sequence analysis showing homology with the ribosomal RNA gene for
P. knowlesi. He responded rapidly to treatment with artemether & lumefantrine combination. The evolution of a rapid diagnostic kit to diagnose
P. knowlesi is needed, for early identification and appropriate anti-malarial therapy of suspect cases are both critical in the prevention of the potentially life-threatening disease through
P. knowlesi. Clinicians need to consider knowlesi infection in the differential diagnosis in recent-onset febrile travellers to areas of forestation in Southeast Asia.
Journal Article
HBO's girls and the awkward politics of gender, race, and privilege
This book studies the HBO program Girls from multiple perspectives by comparing the series to similar programs from the past and present by examining it through the lenses of gender, race, sexuality, and culture.
eBook
Singing and dancing to the Book of Mormon
This volume examines a cultural phenomenon, asking: What made 'The Book of Mormon' such a success? In what ways does the work utilize established artistic traditions (musical theatre, comic tropes), but revise them to create something new? What cultural buttons does the work push in religion and world affairs? What artistic and social boundaries - and the transgression of those boundaries - give the work its edge? What is the effect of the work on particular audiences: in the theatre, in academia, in religious/Mormon studies, and beyond?
eBook
Rabies post-exposure prophylaxis started during or after travel: A GeoSentinel analysis
Recent studies demonstrate that rabies post-exposure prophylaxis (RPEP) in international travelers is suboptimal, with only 5-20% of travelers receiving rabies immune globulin (RIG) in the country of exposure when indicated. We hypothesized that travelers may not be receiving RIG appropriately, and practices may vary between countries. We aim to describe the characteristics of travelers who received RIG and/or RPEP during travel.
We conducted a multi-center review of international travelers exposed to potentially rabid animals, collecting information on RPEP administration. Travelers who started RPEP before (Group A) and at (Group B) presentation to a GeoSentinel clinic during September 2014-July 2017 were included. We included 920 travelers who started RPEP. About two-thirds of Group A travelers with an indication for rabies immunoglobulin (RIG) did not receive it. Travelers exposed in Indonesia were less likely to receive RIG in the country of exposure (relative risk: 0.30; 95% confidence interval: 0.12-0.73; P = 0.01). Travelers exposed in Thailand [Relative risk (RR) 1.38, 95% Confidence Interval (95% CI): 1.0-1.8; P = 0.02], Sri Lanka (RR 3.99, 95% CI: 3.99-11.9; P = 0.013), and the Philippines (RR 19.95, 95% CI: 2.5-157.2; P = 0.01), were more likely to receive RIG in the country of exposure.
This analysis highlights gaps in early delivery of RIG to travelers and identifies specific countries where travelers may be more or less likely to receive RIG. More detailed country-level information helps inform risk education of international travelers regarding appropriate rabies prevention.
Journal Article
Zika beyond the Americas: Travelers as sentinels of Zika virus transmission. A GeoSentinel analysis, 2012 to 2016
Background Zika virus (ZIKV) was first isolated in Africa; decades later, caused large outbreaks in the Pacific, and is considered endemic in Asia. We aim to describe ZIKV disease epidemiology outside the Americas, the importance of travelers as sentinels of disease transmission, and discrepancies in travel advisories from major international health organizations. Methods and findings This descriptive analysis using GeoSentinel Surveillance Network records involves sixty-four travel and tropical medicine clinics in 29 countries. Ill returned travelers with a confirmed or probable diagnosis of ZIKV disease acquired in Africa, Asia and the Pacific seen between 1 January 2012 and 31 December 2016 are included, and the frequencies of demographic, trip, and diagnostic characteristics described. ZIKV was acquired in Asia (18), the Pacific (10) and Africa (1). For five countries (Indonesia, Philippines, Thailand, Vietnam, Cameroon), GeoSentinel patients were sentinel markers of recent Zika activity. Additionally, the first confirmed ZIKV infection acquired in Kiribati was reported to GeoSentinel (2015), and a probable case was reported from Timor Leste (April 2016), representing the only case known to date. Review of Zika situation updates from major international health authorities for country risk classifications shows heterogeneity in ZIKV country travel advisories. Conclusions Travelers are integral to the global spread of ZIKV, serving as sentinel markers of disease activity. Although GeoSentinel data are collected by specialized clinics and do not capture all imported cases, we show that surveillance of imported infections by returned travelers augments local surveillance system data regarding ZIKV epidemiology and can assist with risk categorization by international authorities. However, travel advisories are variable due to risk uncertainties.
Journal Article
Professional organisation profile: A faculty of expedition and wilderness medicine for Australasia
A profile of the recent genesis of the Sub-Faculty of Expedition Medicine into a Faculty of Expedition and Wilderness Medicine of The Australasian College of Tropical Medicine is presented. Information is given on aims, structure, professional grades of membership, and the various activities of the Faculty, including publications and scientific meetings.
Journal Article
Performing American masculinities : the 21st-century man in popular culture
This collection highlights the fluidity of masculinity in American
popular culture at the turn of the new millennium and beyond by examining
possibilities for male identity formation. Each chapter mines American popular
culture -- theatre, film, literature, music, advertising, internet content,
television, photography, and current events -- to pose questions about the process
of gender creation and the contestation of masculinities as constantly changing
political forms. The first section explores masculinities within late capitalism and
includes studies of Seinfeld, Queer Eye for the Straight Guy, and reality
television. The second section addresses identity when masculinity intersects with
race, religion, disability, and sexuality, including chapters on Barack Obama, the
O.J. trial, and popular movies.
eBook
