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Best 10 : 20th Asia-Pacific interior design awards = Di er shi jie Ya Tai shi nei she ji da jiang ji huo jiang zuo pin ji
Asia Pacific Interior Design Awards (APIDA) is organised by the Hong Kong Interior Design Association. It aims to give recognition to outstanding interior design projects and designers, promoting professional standards and ethics among interior design practices operating in the Asia Pacific region. The awards accept the interior design projects completed in the Asia/Pacific Region, including Hong Kong, Mainland China, Taiwan, Singapore, Japan, Malaysia, Macau, Thailand, The Philippines, India, Indonesia, Korea, Australia & New Zealand. This book selects the best projects from the excellent entries for the 20th Asia Pacific Interior Design Awards (APIDA). They fall into chapters, including food space, hotel space, leisure and entertainment space, living space, installation and exhibition space, public space, work space, shopping space and students' projects. This collection shows the readers the wisdom and design ideas of the designers in Asia-pacific region and unveil the design hotspots which belong to the Asia-pacific region.
Book
Human gut microbiome impacts skeletal muscle mass via gut microbial synthesis of the short‐chain fatty acid butyrate among healthy menopausal women
Background Increasing evidence suggests that human gut microbiome plays an important role in variation of skeletal muscle mass (SMM). However, specific causal mechanistic relationship of human gut microbiome with SMM remains largely unresolved. Understanding the causal mechanistic relationship may provide a basis for novel interventions for loss of SMM. This study investigated whether human gut microbiome has a causal effect on SMM among Chinese community‐dwelling healthy menopausal women. Methods Estimated SMM was derived from whole‐body dual‐energy X‐ray absorptiometry. We performed integrated analyses on whole‐genome sequencing, shotgun metagenomic sequencing, and serum short‐chain fatty acids (SCFAs), as well as available host SMM measurements among community‐dwelling healthy menopausal women (N = 482). We combined the results with summary statistics from genome‐wide association analyses for human gut microbiome (N = 952) and SMM traits (N = 28 330). As a prerequisite for causality, we used a computational protocol that was proposed to measure correlations among gut metagenome, metabolome, and the host trait to investigate the relationship between human gut microbiome and SMM. Causal inference methods were applied to assess the potential causal effects of gut microbial features on SMM, through one‐sample and two‐sample Mendelian randomization (MR) analyses, respectively. Results In metagenomic association analyses, the increased capacity for gut microbial synthesis of the SCFA butyrate was significantly associated with serum butyrate levels [Spearman correlation coefficient (SCC) = 0.13, P = 0.02] and skeletal muscle index (SCC = 0.084, P = 0.002). Of interest was the finding that two main butyrate‐producing bacterial species were both positively associated with the increased capacity for gut microbial synthesis of butyrate [Faecalibacterium prausnitzii (SCC = 0.25, P = 6.6 × 10−7) and Butyricimonas virosa (SCC = 0.15, P = 0.001)] and for skeletal muscle index [F. prausnitzii (SCC = 0.16, P = 6.2 × 10−4) and B. virosa (SCC = 0.17, P = 2.4 × 10−4)]. One‐sample MR results showed a causal effect between gut microbial synthesis of the SCFA butyrate and appendicular lean mass (β = 0.04, 95% confidence interval 0.029 to 0.051, P = 0.003). Two‐sample MR results further confirmed the causal effect between gut microbial synthesis of the SCFA butyrate and appendicular lean mass (β = 0.06, 95% confidence interval 0 to 0.13, P = 0.06). Conclusions Our results may help the future development of novel intervention approaches for preventing or alleviating loss of SMM.
Journal Article
القطارات فائقة السرعة في الصين
في هذا الكتاب عرض للمراحل التي مرت بها صناعة «القطارات فائقة السرعة في الصين» حتى وصولها إلى شكلها الحال يحيث أصبحت السكك الحديدية عالية السرعة الصورة الممثلة لاقتصاد الصين الحديث، وبطريقة مماثلة جواز سفر لها وحيث قدر لجهود الحكومة الصينية خلال العقود القليلة الماضية التغلب على التحديات والصعوبات لتنضوي تحت سعي الأمة التاريخي للتجدد واستعادة شبابها كما سرعت تقدم الصين إلى مركز مسرح الاقتصاد العالمي.
BOOK
Food-Grade Pickering Emulsions: Preparation, Stabilization and Applications
In recent years, Pickering emulsions have emerged as a new method and have attracted much attention in the fields of food sciences. Unlike conventional emulsions, Pickering emulsions are stabilized by solid particles, which can irreversibly adsorb on the oil-water interface to form a dense film to prevent the aggregation of droplets. The research and development of food-grade solid particles are increasingly favored by scientific researchers. Compared with conventional emulsions, Pickering emulsions have many advantages, such as fewer using amounts of emulsifiers, biocompatibility and higher safety, which may offer feasibility to have broad application prospects in a wide range of fields. In this article, we review the preparation methods, stabilization mechanism, degradation of Pickering emulsions. We also summarize its applications in food sciences in recent years and discuss its future prospects and challenges in this work.
Journal Article
The surgeon and the pheo: the story behind Dr. Jon van Heerden's 1981 intraoperative self-experiment
In 1981, Hamberger was a visiting surgeon at the Mayo Clinic with a special interest in pheochromocytomas; at his home institution, Karolinska Institutet in Solna, Sweden, Hamberger headed an active research program studying the biochemical activity of these tumors, and he shared his expertise with the team at Mayo during his yearlong visit there. In addition to undergoing the blood draws, van Heerden was also monitored closely with blood pressure and heart rate measurements throughout the operation; these physiologic data would eventually be correlated with the hormone levels from his blood samples, but also helped confirm that van Heerden was not suffering any ill consequences from losing blood or from the indwelling catheter itself. In direct correlation, his systolic blood pressure and heart rate also rose steadily until the moment of vein clipping, then declined. Numerous researchers have performed intraoperative measurements of surgeons' physiology demonstrating elevated heart rates, blood pressure, body temperature and other markers of stress. 1–4 More
Journal Article
Retinal Neurovascular Coupling: From Mechanisms to a Diagnostic Window into Brain Disorders
Retinal neurovascular coupling reflects the precise coordination between neuronal activity, glial support, and vascular responses, mirroring key neurovascular mechanisms in the brain. This review emphasizes the cellular and molecular processes underlying retinal neurovascular coupling and positions the retina as a sensitive and accessible model for investigating neurovascular function in the brain. It highlights how parallel neurovascular degeneration in the brain and retina provides critical insights into the pathophysiology of neurodegenerative and vascular disorders. Advances in retinal imaging, including functional optical coherence tomography (fOCT), OCT angiography (OCTA), and functional electrophysiology, offer unprecedented opportunities to detect early neuronal and vascular dysfunction, establishing the retina as a non-invasive biomarker for early detection, disease monitoring, and therapeutic evaluation in Alzheimer’s, Parkinson’s and Huntington’s disease, and stroke. By integrating structural, functional, and mechanistic approaches, the review emphasizes the retina’s potential as a translational platform bridging basic science and clinical applications in neurovascular research.
Journal Article
جوهر التقاليد الصينية
يندرج هذا الكتاب في إطار دعوة متنامية إلى قيام حوار بين الحضارات تعم العالم بأسره في سياق العولمة الراهنة فهو يبحث بصورة جديدة ومعمقة في جوهر التقاليد الصينية أي في \"روحها\" العميقة و\"مشاعرها\" الكامنة والتي تتشكل من معتقدات المجتمع الصيني وطقوسه والممارسات المؤثرة فيه وفي الكتاب رصد للحركة الثقافية الجديدة التي شهدتها الصين في عشرينيات القرن المنصرم ولا سيما عمل الكونفوشيوسيين الجدد وفيه شرح لفلسفة التناغم الكوني، كمسعى ثقافي وفلسفي عابر للثقافات من غير أن يعني بالضرورة الذوبان في ثقافة الآخر وفقدان الهوية الثقافية الأصيلة.
Book
H3K36 methyltransferase SDG708 enhances drought tolerance by promoting abscisic acid biosynthesis in rice
• Chromatin modifications play important roles in plant adaptation to abiotic stresses, but the precise function of histone H3 lysine 36 (H3K36) methylation in drought tolerance remains poorly evaluated.
• Here, we report that SDG708, a specific H3K36 methyltransferase, functions as a positive regulator of drought tolerance in rice. SDG708 promoted abscisic acid (ABA) biosynthesis by directly targeting and activating the crucial ABA biosynthesis genes NINE-CIS-EPOXYCAROTENOID DIOXYGENASE 3 (OsNCED3) and NINE-CIS-EPOXYCAROTENOID DIOXYGENASE 5 (OsNCED5).
• Additionally, SDG708 induced hydrogen peroxide accumulation in the guard cells and promoted stomatal closure to reduce water loss. Overexpression of SDG708 concomitantly enhanced rice drought tolerance and increased grain yield under normal and drought stress conditions.
• Thus, SDG708 is potentially useful as an epigenetic regulator in breeding for grain yield improvement.
Journal Article