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Designers search for memories and retrieve appropriate mental information during design brainstorming. The specific contents of retrieved memories can serve as stimuli for new ideas, or act as barriers to innovation. These contents can be divided into different categories, which are reflected in designers’ creativities, and derived from individual lives and design experiences. Appropriate categorization of retrieved memory exemplars remains a fundamental research issue. This study tentatively divided retrieved memory exemplars into eight categories from brainstorming on the topic of library desk and chair design. A verification questionnaire was performed and validated the accuracy of categorization. The categorization result could be applied to design education in terms of understanding students’ design performances and capabilities.

The influence of thinking flexibility on design is often underestimated by researchers in the field of design education. In this study, morphological analysis was used as a tool to develop design proposals and eye tracking technology was applied to track the attention. The feature of thinking activities in problem-solving between two groups (novice and expert) was analyzed by Heat map and Gaze plot in qualitative, and measured by indicators such as fixation and saccade in quantitative. Findings suggested that, i) Experts showed more fixation duration and fixation numbers in thinking activities, and the attention containing more AOIs was positively related to the rationality of the scheme. ii) Saccades with greater amplitude were more beneficial to the novelty of scheme. iii) Experts considered the information of each block in a balanced way, while novices tended to ignore unimportant blocks. These results will have a far-reaching impact on the development of designers’ thinking and help novices to exercise creative thinking and produce high-quality designs.

Physical objects and their pictures are two main kinds of design stimuli of creative activity, which can improve design quality but may induce design fixation. Previous studies are focused on the case where participants face a single picture, and their design stimulus may be incomplete as compared with the participants facing objects. To fully explore the influence of physical and pictorial examples on design novices, we investigated design fixation and design quality when they were provided with multiperspective pictures having information remarkably similar to physical objects. Specifically, two novice groups individually created their own designs after observing several examples by the way of the above two presentation modes. These designs were evaluated by two evaluators in terms of similarity, originality, and completeness. Statistical analysis showed that no significant difference was found in similarity and originality between the two groups, whereas the designs of the physical group outperformed those of the pictorial group in terms of completeness. This finding indicated that the two groups showed the same degree of design fixation, as multiperspective pictures presented most of the form information of the physical object. The results suggest that when instructing design novices, it is essential to control how to present design examples at different stages of the design process.

A new cytotoxic pentacyclic alkaloid, citrinadin C (1), together with four known compounds (2–5), were isolated from deep-sea-derived fungus Penicillium citrinum. The structure of new compound 1 was elucidated by extensive 1D and 2D NMR and Mass spectroscopic data, and its absolute configuration was determined by CD spectrum. All the compounds were evaluated for their cytotoxic and antibacterial activities. Compound 1 showed cytotoxic activities against human liver cancer cell line MHCC97H, with IC50 value of 16.7 μM. Compound 4 displayed significant antibacterial activity against phytopathogen Xanthomonas campestris, with MIC value of 25 μM.

Culture, as an intangible piece of heritage, is one of the priorities of sustainable conservation. With the rapid modernization of science and technology, traditional culture that is expressed in the form of sound is facing prominent problems related to inheritance and development. Thinking about how to integrate traditional culture into the daily life of the public is an important way of solving sustainability problems related to traditional culture. This study took Guqin culture as its research object, explored the possibility of using sound as an interactive medium, and considered how to present traditional culture to the public in public space to broaden the inheritance and development mode of Guqin culture. Therefore, this study proposes a public Sound Interaction Design Model oriented to sound and presents a public sound-interactive installation with different levels based on the model. The feasibility of the model is verified through an interactive design evaluation method, and the role of the model in sustainable cultural development is discussed.

The bio-oil phenol-formaldehyde (BPF) resin, prepared by using bio-oil as a substitute for phenol, has similar bonding strength but lower price to phenol-formaldehyde (PF) resin. As a common adhesive for outdoor wood, the aging performance of BPF resin is particularly important. The variations in mass, bonding strength, microstructure, atomic composition, and chemical structure of BPF resin under five aging conditions (heat treatment, water immersion, UV exposure, hydrothermal treatment, and weatherometer treatment) were characterized by scanning electron microscope, X-ray photoelectron spectroscopy, and Fourier transform infrared spectroscopy, respectively. Compared under five aging conditions, after aging 960 h, the mass loss of plywood and film was largest under hydrothermal treatment; the bonding strength of plywood, the surface roughness, and O/C ratio of the resin film changed most obviously under weatherometer treatment. FT-IR analysis showed that the decreased degree of peak intensity on CH2 and C–O–C characteristic peaks of BPF resin were weaker under water immersion, hydrothermal treatment, and weatherometer treatment than those of PF resin. The comparison of data between BPF and PF resins after aging 960 h showed that adding bio-oil could obviously weaken the aging effect of water but slightly enhance that of heat. The results could provide a basis for the aging resistance modification of BPF resin.

The most critical factor determining the success of biodegradable bone implants is the host tissue response, which greatly depends on their degradation behaviors. Here, a new magnesium‐based implant, namely magnesium–silicon–calcium (Mg–0.2Si–1.0Ca) alloy, that coordinates its biodegradation along with the bone regenerative process via a self‐assembled, multilayered bone–implant interface is designed. At first, its rapid biocorrosion contributes to a burst release of Mg2+, leading to a pro‐osteogenic immune microenvironment in bone. Meanwhile, with the simultaneous intervention of Ca and Si in the secondary phases of the new alloy, a hierarchical layered calcified matrix is rapidly formed at the degrading interface that favored the subsequent bone mineralization. In contrast, pure Mg or Mg–0.2Si alloy without the development of this interface at the beginning will unavoidably induce detrimental bone loss. Hence, it is believed this biomimicking interface justifies its bioadaptability in which it can modulate its degradation in vivo and accelerate bone mineralization. The spontaneously formed degradation layers at the bone–implant interface are the key to the superior performance of Mg–Si–Ca alloy, as they regulate the biodegradation behaviors of the implant to elicit an appropriate host response at different stages of bone healing.

The intricate degradation dynamics exhibited by biodegradable alloys significantly influence host responses during the implantation process, posing challenges in achieving stable osseointegration. It is thus critical to tailor the biodegradation profiles of these implants to establish a conductive tissue microenvironment for bone tissue regeneration. In this study, we demonstrate that Zn-Li alloy forms a layer of Li-containing degradation products at the bone-implant interface to accommodate the bone regeneration process. During the early inflammatory phase, the controlled release of lithium ions (Li+) and zinc ions (Zn2+) from the alloy induces chemokine (C-C motif) ligand 5 (CCL5) production from macrophages, which promotes the recruitment and differentiation of osteoblastic lineage cells. As a protective bone-implant interface is formed subsequently, the active Zn2+ release from Zn-Li alloy is suppressed while Li+ continues to exhibit anti-inflammatory effects and inhibit osteoclastogenesis. Therefore, the presence of Li in Zn-based alloy prevents the prolonged inflammation and fibrous capsulation typically seen in pure Zn implants. Our findings offer valuable insights into the development of novel biodegradable implants aimed at achieving osseointegration through bioadaption. The intricate degradation dynamics exhibited by biodegradable alloys significantly influence host responses during the implantation process. Lithium alloying tailored the biodegradation profile of Zn-based implant to achieve bioadaption to the bone. With Li-containing protective layer formed at the bone-implant interface, biodegradation of Zn-Li implant creates a favorable immune microenvironment to promote osseointegration. [Display omitted] •Zn-Li alloy forms a Li-containing degradation layer at the bone-implant interface to adapt the bone regeneration process.•Zn-Li alloy induces the secretion of CCL5 to promote the recruitment and differentiation of osteoblastic lineage cells.•Li in Zn-based alloy prevents the prolonged inflammation and fibrous capsulation typically seen in pure Zn implants.

Increasing attention is being given to traditional culture-orientated product design. While Chinese design students lack a deep understanding of traditional Chinese culture and its applications, little in-depth research has investigated this issue. Thus, how educators should guide and improve their students’ cultural design in the context of current Chinese design education and practices remains unclear. This study explores these design students’ cognition and application of different levels of Chinese cultural design elements to provide new insights for improving and adapting cultural design teaching practices. This study comprised three related stages. In stage 1, we extracted three levels of 15 representative cultural design elements from Chinese culture based on cultural hierarchy theory. In stage 2, we examined the students’ cognition about different levels of cultural elements using two questionnaire surveys. In stage 3, we further compared the differences in the application of cultural elements between experts and students to explore the students’ cultural application ability. The results showed that different design students have differing cognition of Chinese culture, which can be divided into two categories: i.e., cognitive deficiency or sufficiency. Compared with experts, students lack application experience and ability in the design elements of inner ‘intangible’ and middle ‘behavioural’ levels, because of their insufficient understanding of these two cultural design levels. These findings may reveal deficiencies in Chinese design students’ cognition and application, and provide targeted cultural teaching guidance.

Indoor soundscape research has developed rapidly in recent years, with the aim of improving the single indoor noise reduction method and people’s acoustic comfort. However, practical solutions to promote the generation of positive indoor soundscapes are still insufficient. The purpose of this study was to explore the improvement effect of ceramic passive amplifiers on the indoor soundscape and the relationship between the improvement effect and different amplifier shapes. Objective sound pressure level (SPL) values and subjective soundscape perception were measured for 10 ceramic passive amplifiers based on the soundscape, mainly using a comparative method. Ten sample amplifiers were compared with the acoustic data of the original open-plan studio environment, and then with an electronic sound amplifier. The results show that ceramic passive amplifiers can improve the quality of the indoor soundscape by creating sound scenes with appropriate loudness. Regarding non-acoustic aspects, the shape and materials of ceramic passive amplifiers play a positive role in emotional guidance.