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9
result(s) for
"Simou, Magdalini"
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Retraction: Splenic Injury After Colonoscopy in a 55-Year-Old Female Patient
2023
[This retracts the article DOI: 10.7759/cureus.35239.].
Journal Article
Splenic Injury After Colonoscopy in a 55-Year-Old Female Patient
2023
Colonoscopy is, in general, a relatively safe procedure with a low complication rate. Splenic injury related to this procedure is very rare, ranging from one in 100,000 to one in 6,387 colonoscopies, but a possibly lethal complication. For its diagnosis, a high degree of clinical suspicion is needed as many physicians are not aware of its existence. Clinical symptoms and signs are observed 1-10 days after the procedure. The imaging modality of choice is contrast-enhanced computed tomography (CECT). However, contrast-enhanced ultrasound (CEUS) may also be used to detect abdominal fluid and the injured area of the spleen. We present a case of a 55-year-old female with splenic rupture after a colonoscopy, diagnosed with CEUS and CECT. Splenectomy was performed, and the patient's recovery was uneventful.
Journal Article
A Rare Case of Synchronous Primary Gallbladder and Sigmoid Colon Neoplasms
by
Lintzeris, Ioannis
,
Simou, Magdalini
,
Stylianidis, Georgios
in
Abdomen
,
Cancer therapies
,
Case reports
2023
Colorectal cancer is considered the third most common cancer worldwide. On the other hand, gallbladder cancer is rare. Synchronous tumors in both the colon and the gallbladder are extremely infrequent. Herein, we report the case of a female patient with sigmoid colon cancer and incidental detection of synchronous gallbladder cancer on histopathological examination of the surgical specimen. As synchronous gallbladder and colonic carcinomas are rare, physicians should be aware of these so that an optimal course of treatment can be chosen.
Journal Article
Large-Cell Esophageal Neuroendocrine Carcinoma: Report of a Rare Case
by
Floros, Georgios
,
Galanis, Ilias
,
Simou, Magdalini
in
Biomarkers
,
Cancer therapies
,
Case reports
2022
Neuroendocrine tumors (NETs) are neoplasms with neuroendocrine characteristics such as secretion of neuropeptides, large secretory vesicles, and a lack of neural structures. Neuroendocrine carcinoma (NEC) of the esophagus is a very rare malignancy. We present the case of a 58-year-old male with a pure large cell NEC of the esophagus.
Journal Article
An Extremely Rare Case of a Primary Pancreatic Yolk Sac Tumor
by
Floros, Georgios
,
Kyriakopoulos, Georgios
,
Simou, Magdalini
in
Case reports
,
Chemotherapy
,
General Surgery
2022
Yolk sac tumor (YST) is a rare malignant type of germ cell tumor (GCT). Extragonadal yolk sac tumor is a very rare entity. We report the case of a 33-year-old male with a pancreatic mass, which proved to be a primary yolk sac tumor, arising in the pancreas.
Journal Article
Cholesteatoma: diagnosis, management and follow-up, and an interesting case report
by
Simou, Dimitra
,
Lianou, Aikaterini
,
Bizoglou, Magdalini
in
Congenital diseases
,
Ear diseases
,
Eardrum
2025
Cholesteatomas are benign tumors composed of skin-related substances. They can extensively infiltrate the ear and compromise surrounding structures, requiring surgical removal. Computed tomography can assist with surgical planning by illustrating the position and impact of the cholesteatoma. Recent advancements in magnetic resonance imaging have demonstrated enhanced visualization of cholesteatomas. Whereas additional surgical intervention was formerly necessary to identify cholesteatoma recurrence, magnetic resonance imaging can now often serve as an alternative. This paper reviews the current evidence on diagnosing, managing, and following up with patients with cholesteatoma. It also presents an interesting case that highlights the value of diffusion-weighted imaging (DWI), even in cases of initial diagnosis.
Journal Article
Obesity-Related Inflammatory Biomarkers in the Elderly Population
2025
Obesity in elderly individuals is associated with increased levels of inflammatory biomarkers, indicating a state of chronic low-grade inflammation, which has been recently termed as adipaging. Several studies have demonstrated this relationship: overweight and obese middle-aged and elderly individuals show elevated levels of inflammatory markers like CXCL-16, IL-6, and adipokines compared to normal weight counterparts. These markers positively correlate with anthropometric parameters indicating increased cardiovascular risk. C-reactive protein (CRP) and fibrinogen levels increase progressively with higher obesity classes in the general population, including the elderly. For instance, CRP levels nearly double with each increase in weight class compared to normal weight individuals. Additionally, the presence of obesity-related comorbidities like hypertension or diabetes further elevates these inflammatory markers. In conclusion, obesity in the elderly is characterized by elevated levels of various inflammatory biomarkers, reflecting a state of chronic low-grade inflammation. This inflammatory state may contribute to the development of obesity-related comorbidities. The clarification of the complementary or independent role of these biomarkers in aging and obesity could lead to targeted therapeutic interventions in this vulnerable population group.
Journal Article
The Reconstruction of Nasal Cutaneous Defects With Locoregional Flaps
2025
The nose occupies the central position on the face and may be the most difficult facial feature to reconstruct due to its complex anatomy and function. Cancer resection and trauma are the most common causes of nasal defects. The goal in such cases is to select the most appropriate option for a given defect to preserve nasal function and to achieve the best aesthetic outcome. The most important aspect of a successful reconstruction is preoperative planning. Although small defects may only require a single procedure and primary closure might be an option, multiple procedures are typically needed to reconstruct a more extensive defect to prevent nasal distortion or collapse. Locoregional flaps are the first choice for reconstruction as they use nearby tissue, providing an excellent color and texture match with the best results. The objective of this article is to engage in a review of the most common locoregional flaps used to reconstruct cutaneous nasal defects. We analyze the most commonly used locoregional flaps, as well as their advantages and disadvantages.
Journal Article