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Exposure to traumatic stress leads to persistent, deleterious behavioral and biological changes in both human and non-human species. The effects of stress are not always consistent, however, as exposure to different stressors often leads to heterogeneous effects. The intensity of the stressor may be a key factor in determining the consequences of stress. While it is difficult to quantify intensity for many stress types, electric shock exposure provides us with a stressor that has quantifiable parameters (presentation length x intensity x number = shock volume). Therefore, to test the procedural differences in shock volume that may account for some reported heterogeneity, we used two common shock procedures. Learned helplessness is a commonly reported behavioral outcome, highlighted by a deficit in subsequent shuttle-box escape, which requires a relatively high-volume stress (HVS) of about 100 uncontrollable shocks. Conversely, stress-enhanced fear learning (SEFL) is another common behavioral outcome that requires a relatively moderate-volume stress (MVS) of only 15 shocks. We exposed rats to HVS, MVS, or no stress (NS) and examined the effects on subsequent fear learning and normal weight gain. We found doubly dissociable effects of the two levels of stress. MVS enhanced contextual fear learning but did not impact weight, while HVS produced the opposite pattern. In other words, more stress does not simply lead to greater impairment. We then tested the hypothesis that the different stress-induced sequalae arouse from an energetic challenge imposed on the hippocampus by HVS but not MVS. HVS rats that consumed a glucose solution did exhibit SEFL. Furthermore, rats exposed to MVS and glucoprivated during single-trial context conditioning did not exhibit SEFL. Consistent with the hypothesis that the inability of HVS to enhance fear learning is because of an impact on the hippocampus, HVS did enhance hippocampus-independent auditory fear learning. Finally, we provide evidence that stressors of different volumes produce dissociable changes in glutamate receptor proteins in the basolateral amygdala (BLA) and dorsal hippocampus (DH). The data indicate that while the intensity of stress is a critical determinant of stress-induced phenotypes that effect is nonlinear.

Background Feed additives which can ease the negative effects of infection by the Aleutian mink disease virus (AMDV) are of interest to mink farmers. The effects of kelp meal ( Ascophylum nodosum ) supplementation on immune response, virus replication and blood parameters of mink inoculated with AMDV were assessed. AMDV-free black mink ( n  = 75) were intranasally inoculated with a local strain of AMDV and fed a commercial pellet supplemented with kelp meal at the rates of 1.5% or 0.75% of the feed or were kept as controls (no kelp) for 451 days. Blood was collected on days 0 (pre-inoculation), 31, 56, 99, 155, 366 and 451 post-inoculation (dpi). Results No significant difference was observed among the treatments for the proportion of animals positive for antibodies against the virus measured by the counter-immunoelectrophoresis (CIEP), viremia measured by PCR, antibody titer measured by quantitative ELISA, total serum protein measured by a refractometer or elevated levels of gamma globulin measured by iodine agglutination test at the sampling occasions. At the termination of the experiment on 451 dpi, there were no differences among treatments for antibody titer measured by CIEP, total serum protein, albumin, globulins, albumin:globulin ratio, alkaline phosphatase, gamma-glutamyl transferase, and proportions of PCR positive spleen, lymph node or bone marrow samples, but blood urea nitrogen and creatine levels were significantly lower in the 1.5% kelp supplemented group than in the controls. Conclusion Kelp supplementation improved kidney function of mink infected with AMDV with no effect on liver function, immune response to infection by AMDV or virus replication.

This article examines the practice and meanings of the new veiling and of Islamization more generally for young Muslim Javanese women in the new middle class. Drawing on eight months of ethnographic research in the Central Java city of Yogyakarta in 1999 and three subsequent one-month visits during 2001, 2002, and 2003, I explore the social and religious attitudes of female students at two of Yogyakarta's leading centers of higher education: Gadjah Mada University, a nondenominational state university, and the nearby Sunan Kalijaga National Islamic University. The ethnographic and life-historical materials discussed here underscore that the new veiling is neither a traditionalist survival nor an antimodernist reaction but rather a complex and sometimes ambiguous effort by young Muslim women to reconcile the opportunities for autonomy and choice offered by modern education with a heightened commitment to the profession of Islam.

This article examines the linguistic form and social functions of bahasa gaul, the informal Indonesian \"language of sociability,\" as it is used among Indonesian university students and in various publications aimed at middle-class Indonesian youth. Bahasa gaul registers youth modernity in both its positive and more contested aspects. It expresses not only young people's aspirations for social and economic mobility, but also an increasingly cosmopolitan, national youth culture. Perhaps most significantly, bahasa gaul articulates the desire of Indonesian youth for new types of social belonging through the formulation of relationships that are more egalitarian and interactionally fluid as well as more personally expressive and psychologically individualized.

This article explores the shift away from formal styles of Javanese to the use of the national language, Indonesian, within the context of new educational and social opportunities for Javanese youth. It focuses on gender differences in language attitudes and considers how socialization and cultural ideologies regarding men's and women's relationship to language shape those attitudes. Recent changes in possibilities for social and status mobility linked to language use have challenged traditional language ideologies and have led Javanese men and women to develop different language strategies and patterns of interaction. A new subjective concern with emotional and interpersonal expressivity among youth—particularly among young women—is identified as an important mediating valence in the shift to varieties of Indonesian identified as more \"communicative\" and \"participatory.\"

Qualitative analysis of three discipline-specific focus groups (graduate students in educational leadership/educational administration, curriculum and instruction, and counseling) revealed that these participants are largely unprepared to serve students with extensive and pervasive support needs. Rather, these professionals reported relying upon their ability to learn from others, their personal experiences, and their capacity to “take risks and fake it.” They cited numerous barriers to effective implementation of inclusion revealing that they were often afraid to ask for clarification and support; had limited opportunities for meaningful collaboration; engaged with a system that often placed form over function; and worked with students who experienced segregation, neglect, and isolation. Participants offered suggestions for improving university-based preparation, enhancing professional development, and increasing hands-on learning opportunities along with the need to create a supportive system for educators, students, and their families.

this article explores changing attitudes towards courtship and marriage among educated muslim javanese youth, as seen against the backdrop of islamic resurgence, growing educational achievement and socioeconomic change. through a comparison of earlier forms of courtship and marriage with emerging trends, it sheds light on some of the tensions and ambivalences surrounding the new social freedoms and autonomy modern javanese women have come to enjoy.

This study examined the effect of aerobic interval training on cardiac adaptations in VLCAD-deficient mice and determined the effects of the deficiency on the morphology and function of the left ventricle among 53 knockout homozygous VLCAD−/−, 28 heterozygous VLCAD±, and 39 controls VLCAD+/+ male mice (129 SvJ/C57BL6). Echocardiographic images were used to determine the left ventricular (LV) wall thicknesses, during systole and diastole, acquired at a depth setting of 20 mm. Cardiac hypertrophy (as evidenced by increased wall thickness, and decreased left ventricular dimension in diastole and systole) appeared to be a major finding in the VLCAD−/− mouse with, however, normal %FS. The trained mice from all three genotypes exhibited lower body weight compared with their controls. The echocardiographic data of this study demonstrated structural but not functional differences among the three genotypes. This study demonstrated that VLCAD± deficient mice handled interval training similarly to the non-deficient mice. Four VLCAD−/− deficient mice died unexpectedly on the treadmill during the early stages of training. The VLCAD−/− deficient mice that survived adapted to the aerobic interval training similarly to the non-deficient mice. It is unclear whether aerobic interval training is an appropriate training tool for the VLCAD-deficient humans.