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Paul Bunyan
Relates in graphic novel format some of the exploits of Paul Bunyan, a lumberjack said to be taller than the trees whose pet was a blue ox named Babe.
Book
Field guide to grasses of California
Grasses and grasslands are of increasing interest to conservationists, biologists, and gardeners. There are more than 300 species of native California grasses and they are found in almost every climate—from cool, wet forests to hot, dry deserts. Native grasses are also important to land restoration as they improve soil quality, increase water infiltration, and recycle nutrients. Their deep roots can tap soil water, which allows them to stay green year-round and to act as fire buffers around residences. Native grasses also provide vital habitat for many species of insects, birds, reptiles, and mammals. Despite their importance, grasslands remain one of the most underprotected of California's vegetation types, and native grasslands have undergone the greatest percentage loss of any habitat type in the state. Grasses are also among the most difficult plants to identify. Organized alphabetically, Field Guide to Grasses of California covers common native and naturalized grasses and, to help identify them, also features over 180 color illustrations.
eBook
Ultra-high-resolution observations of persistent null-point reconnection in the solar corona
Magnetic reconnection is a key mechanism involved in solar eruptions and is also a prime possibility to heat the low corona to millions of degrees. Here, we present ultra-high-resolution extreme ultraviolet observations of persistent null-point reconnection in the corona at a scale of about 390 km over one hour observations of the Extreme-Ultraviolet Imager on board Solar Orbiter spacecraft. The observations show formation of a null-point configuration above a minor positive polarity embedded within a region of dominant negative polarity near a sunspot. The gentle phase of the persistent null-point reconnection is evidenced by sustained point-like high-temperature plasma (about 10 MK) near the null-point and constant outflow blobs not only along the outer spine but also along the fan surface. The blobs appear at a higher frequency than previously observed with an average velocity of about 80 km s
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and life-times of about 40 s. The null-point reconnection also occurs explosively but only for 4 minutes, its coupling with a mini-filament eruption generates a spiral jet. These results suggest that magnetic reconnection, at previously unresolved scales, proceeds continually in a gentle and/or explosive way to persistently transfer mass and energy to the overlying corona.
Magnetic reconnection is a fundamental energy release mechanism in space and laboratory plasmas. Here, the authors show persistent magnetic null-point reconnection in the solar corona at a scale of about 390 km.
Journal Article
Bacterial defences: mechanisms, evolution and antimicrobial resistance
Throughout their evolutionary history, bacteria have faced diverse threats from other microorganisms, including competing bacteria, bacteriophages and predators. In response to these threats, they have evolved sophisticated defence mechanisms that today also protect bacteria against antibiotics and other therapies. In this Review, we explore the protective strategies of bacteria, including the mechanisms, evolution and clinical implications of these ancient defences. We also review the countermeasures that attackers have evolved to overcome bacterial defences. We argue that understanding how bacteria defend themselves in nature is important for the development of new therapies and for minimizing resistance evolution.In this Review, Smith, Foster and colleagues explore the protective strategies of bacteria, including the mechanisms, evolution and clinical implications of these ancient defences. They discuss new therapies for treating disease and how to minimize resistance evolution.
Journal Article
Increasing Incidence of the Neonatal Abstinence Syndrome in U.S. Neonatal ICUs
This study of U.S. neonatal intensive care units from 2004 through 2013 showed a substantial increase over time in admissions for the neonatal abstinence syndrome and increases in associated length of stay and the percentage of NICU days nationwide attributed to the syndrome.
The neonatal abstinence syndrome is a drug-withdrawal syndrome that most commonly occurs after in utero exposure to opioids. It typically manifests in the first few days of life as hypertonia, autonomic instability, irritability, poor sucking reflex, impaired weight gain, and less commonly, seizures.
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From 2000 through 2009, the incidence of the neonatal abstinence syndrome in the United States nearly tripled,
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with several states reporting even larger recent increases.
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,
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This rise occurred in association with an increase in the use of opioids by pregnant women.
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–
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Despite the increased incidence of the neonatal abstinence syndrome, data on changes in the . . .
Journal Article
Development and Characterization of a High Density SNP Genotyping Assay for Cattle
The success of genome-wide association (GWA) studies for the detection of sequence variation affecting complex traits in human has spurred interest in the use of large-scale high-density single nucleotide polymorphism (SNP) genotyping for the identification of quantitative trait loci (QTL) and for marker-assisted selection in model and agricultural species. A cost-effective and efficient approach for the development of a custom genotyping assay interrogating 54,001 SNP loci to support GWA applications in cattle is described. A novel algorithm for achieving a compressed inter-marker interval distribution proved remarkably successful, with median interval of 37 kb and maximum predicted gap of <350 kb. The assay was tested on a panel of 576 animals from 21 cattle breeds and six outgroup species and revealed that from 39,765 to 46,492 SNP are polymorphic within individual breeds (average minor allele frequency (MAF) ranging from 0.24 to 0.27). The assay also identified 79 putative copy number variants in cattle. Utility for GWA was demonstrated by localizing known variation for coat color and the presence/absence of horns to their correct genomic locations. The combination of SNP selection and the novel spacing algorithm allows an efficient approach for the development of high-density genotyping platforms in species having full or even moderate quality draft sequence. Aspects of the approach can be exploited in species which lack an available genome sequence. The BovineSNP50 assay described here is commercially available from Illumina and provides a robust platform for mapping disease genes and QTL in cattle.
Journal Article