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2,311 result(s) for "Stephen Turner"
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The calling of social thought
Edward Shils was a central figure in twentieth century social thought. He held appointments both at Chicago and Cambridge and was a crucial link between British and American intellectual life. This volume collects essays by distinguished contributors which deal with the major facets of Shils’ thought, including his relations with Michael Polanyi, his parallels with Michael Oakeshott, his defense of the traditional university, his fundamental philosophical anthropology, and his important work on such topics as tradition, civility, and the nation. As an introduction to this complex and original thinker, it will be of interest to scholars and students in a number of fields, including sociology and social theory, but also to anyone interested in the intellectual life as it was lived in the mid-twentieth century, in the face of the Cold War and ideological struggle.
Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data
Unlike hybrid approaches that use multiple libraries for de novo assembly, the hierarchical genome-assembly process uses data from only a single long-read SMRT sequencing library to produce high-quality finished microbial genome or BAC assemblies in an automated workflow. We present a hierarchical genome-assembly process (HGAP) for high-quality de novo microbial genome assemblies using only a single, long-insert shotgun DNA library in conjunction with Single Molecule, Real-Time (SMRT) DNA sequencing. Our method uses the longest reads as seeds to recruit all other reads for construction of highly accurate preassembled reads through a directed acyclic graph–based consensus procedure, which we follow with assembly using off-the-shelf long-read assemblers. In contrast to hybrid approaches, HGAP does not require highly accurate raw reads for error correction. We demonstrate efficient genome assembly for several microorganisms using as few as three SMRT Cell zero-mode waveguide arrays of sequencing and for BACs using just one SMRT Cell. Long repeat regions can be successfully resolved with this workflow. We also describe a consensus algorithm that incorporates SMRT sequencing primary quality values to produce de novo genome sequence exceeding 99.999% accuracy.
PLANES: Plausibility analysis of epidemiological signals
Methods for reviewing epidemiological signals are necessary to building and maintaining data-driven public health capabilities. We have developed a novel approach for assessing the plausibility of infectious disease forecasts and surveillance data. The PLANES ( PL ausibility AN alysis of E pidemiological S ignals) methodology is designed to be multi-dimensional and flexible, yielding an overall score based on individual component assessments that can be applied at various temporal and spatial granularities. Here we describe PLANES, provide a demonstration analysis, and discuss how to use the open-source rplanes R package. PLANES aims to enable modelers and public health end-users to evaluate forecast plausibility and surveillance data integrity, ultimately improving early warning systems and informing evidence-based decision-making.
The calling of social thought : rediscovering the work of Edward Shils
Edward Shils was a central figure in 20th century social thought. He held appointments both at Chicago and Cambridge and was a crucial link between British and American intellectual life. This volume collects essays by distinguished contributors which deal with the major facets of Shils' thought, including his relations with Michael Polanyi, his parallels with Michael Oakeshott, his defense of the traditional university, his fundamental philosophical anthropology, and his important work on such topics as tradition, civility, and the nation. As an introduction to this complex and original thinker, it will be of interest to scholars and students in a number of fields, including sociology and social theory, but also to anyone interested in the intellectual life as it was lived in the mid-20th century, in the face of the Cold War and ideological struggle.
Fellini : the Sixties
\"Fellini: The Sixties is a stunning photographic journey through the director's most iconic classics: La Dolce Vita, 81/2, Juliet of the Spirits, and Fellini Satyricon. Carefully selected imagery from the Independent Visions photographic archive, many published here for the first time, illuminate these films as they have never been seen before, and reveal fascinating details of the director's working style and ebullient personality. With more than 150 photographs struck from original negatives, these images spring to life from the page with the depth and quality of the films themselves. Complemented with insightful essays from contemporary writers, Fellini: The Sixties is a true testament to the man and his work, a remarkable compendium of the legendary filmmaker's greatest achievements\"--Jacket.