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The coins of the English East India Company : presidency series
This catalogue presents a list of all coins known to have been issued by the East India Company for use in their Presidencies of Bengal, Bombay and Madras. Each of the main sections covers the coins of one Presidency with chapters on the coins issued from the main mint in the area ? Calcutta, Bombay or Madras ? as well as chapters on coins issued from local and transitional mints, most of which were not covered in Major Pridmore?s seminal work on the subject.
Book
Summary of KDIGO 2012 CKD Guideline: behind the scenes, need for guidance, and a framework for moving forward
The 2012 KDIGO Guideline for CKD evaluation, classification, and management has updated the original 2002 KDOQI Guidelines, using newer data and addressing issues raised over the last decade concerning definitions and assessment. This review highlights the key aspects of the CKD guideline, and describes the rationale for specific wording and the scope of the document. A précis of key concepts in each of the five sections of the guideline is presented. The guideline document is intended for general practitioners and nephrologists, and covers CKD evaluation, classification, and management for both adults and children. Throughout the guideline, we have attempted to overtly address areas of controversy or non-consensus, international relevance, and impact on practice and public policy.
Journal Article
Six amendments : how and why we should change the Constitution
By the time of his retirement in June 2010, the author had become the second longest serving Justice in the history of the Supreme Court. Now he draws upon his more than three decades on the Court, during which he was involved with many of the defining decisions of the modern era, to offer a book articulating not only the need for changes, but also what those improvements should be. This is a call to arms, detailing six specific ways in which the Constitution should be amended in order to protect our democracy and the safety and wellbeing of American citizens.-- Source other than Library of Congress.
Book
Pietas in Patriam: Milton’s Classical Patriotism
The subject of this essay is the relation between Milton’s classical patriotism and his English nationalism. It has two principal aims. First, it sets out to examine the degree to which the affective or emotional quality of Milton’s patriotism was shaped by the classics, especially Cicero and Virgil. For all the energy that has gone into studying Milton’s classical republicanism, there has been relatively little interest in that political movement’s central concern with patriotism: few, for instance, have shown much interest in David Norbrook’s acknowledgment that “English republicanism emerged in part as a vehicle for English nationalism.” And second, through this focus on the classical aspect of Milton’s patriotism, it argues that far from being neutralized or undercut, Milton’s nascent nationalism was actually enabled and intensified by his internationalism, an internationalism that is most graphically illustrated by his engagement with Italy and its role in recovering the classics.
Journal Article
The making of a justice : reflections on my first 94 years
\"A masterful and personal account of life on the Supreme Court that offers a unique understanding of American history from one of the most prominent jurists of our time. When Justice John Paul Stevens retired from the Supreme Court of the United States in 2010, he left a legacy of service unequaled in the history of the Court. During his thirty-four-year tenure, Justice Stevens was a prolific writer, authoring in total more than 1000 opinions. In The Making of a Justice, John Paul Stevens recounts the first ninety-four years of his extraordinary life, offering an intimate and illuminating account of his service on the nation's highest court. Appointed by President Gerald Ford and eventually retiring during President Obama's first term, Justice Stevens has been witness to, and an integral part of, landmark changes in American society. With stories of growing up in Chicago, his work as a naval traffic analyst at Pearl Harbor during World War II, and his early days in private practice, as well as a behind-the-scenes look at some of the most important Supreme Court decisions over the last four decades, The Making of a Justice offers a warm and fascinating account of Justice Stevens' unique and transformative American life. This comprehensive memoir is a must read for those trying to better understand our country and the Constitution.\"--Jacket.
Book
Change in the estimated glomerular filtration rate over time and risk of all-cause mortality
Using a community-based cohort we studied the association between changes in the estimated glomerular filtration rate (eGFR) over time and the risk of all-cause mortality. We identified 529,312 adults who had at least three outpatient eGFR measurements over a 4-year period from a provincial laboratory repository in Alberta, Canada. Two indices of change in eGFR were evaluated: the absolute annual rate of change (in ml/min per 1.73m2 per year) and the annual percentage change (percent/year). The adjusted mortality risk associated with each category of change in eGFR was assessed, using stable eGFR (no change) as the reference. Over a median follow-up of 2.5 years there were 32,372 deaths. Compared to the reference participants, those with the greatest absolute annual decline less than or equal to 5ml/min per 1.73m2 per year had significantly increased mortality (hazard ratio of 1.52) adjusted for covariates and kidney function at baseline (last eGFR measurement). Participants with the greatest increase in eGFR of 5ml/min per 1.73m2 per year or more also had significantly increased mortality (adjusted hazard ratio of 2.20). A similar pattern was found when change in eGFR was quantified as an annual percentage change. Thus, both declining and increasing eGFR were independently associated with mortality and underscore the importance of identifying change in eGFR over time to improve mortality risk prediction.
Journal Article
The Kidney Disease Improving Global Outcomes (KDIGO) Guideline Update for Chronic Kidney Disease: Evolution not Revolution
[...]an additional dimension has been added to the CKD staging system. Looking ahead, we predict a future when a more sophisticated classification emerges-perhaps underpinned by molecular diagnostics-in which cys- tatin C and other markers are used more widely to re- fine our measurement of GFR, other specific urinary markers are used to assess kidney damage, an accurate determination of cause completes a multidimensional picture of an individual CKD patient, and clinical lab- oratories may use routine tests to compute and report prognosis.
Journal Article
The weighty word book
Provides definitions for twenty-six vocabulary words from abasement to zealot with stories containing puns that provide mnemonic devices for remembering the definitions.
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Early detection of CKD: the benefits, limitations and effects on prognosis
This Review focuses on early detection of chronic kidney disease (CKD) and highlights its associations with cardiac disease and other comorbidities that contribute to poor outcomes. The authors describe the role of estimated glomerular filtration rate and albuminuria in identifying early CKD, examine the benefits of early CKD detection, and describe the limitations of current knowledge with respect to screening, early detection and treatment.
The past decade has seen an increasing focus on chronic kidney disease (CKD) and its attendant complications, which has resulted in improved understanding of their impact on health-care resources. The early detection of CKD has been facilitated by the implementation of routine reporting of estimated glomerular filtration rates (eGFRs) and by education of primary care physicians on the implications of detecting a decreased eGFR with respect to patient safety as well as to cardiovascular and renal outcomes. The goals of early CKD detection are to prevent CKD progression and associated complications, thus improving patient outcomes and reducing the impact of CKD on health-care resources. This Review examines the benefits of the early detection of CKD, and describes the limitations of current knowledge with respect to screening, early detection and treatment, as well as the unintended consequences of detection. In addition, this article highlights what is currently known about cardiovascular and renal outcomes and the effects of intervention in patients with CKD.
Key Points
Chronic kidney disease (CKD) is prevalent worldwide and occurs in conjunction with cardiovascular disease and diabetes
CKD should be defined in terms of both estimated glomerular filtration rates and albuminuria, as each is an independent predictor of prognosis with respect to renal and cardiovascular outcomes
Early detection of CKD allows implementation of treatments and strategies that can influence both progression of kidney disease and cardiovascular health
Detection and identification of CKD facilitates avoidance of drugs and situations that may cause worsening of kidney function and acute kidney injury
CKD is recognized to have widely varying outcomes, which makes predicting the prognosis of individual patients difficult
Improved prediction of renal and other risks in patients with CKD is a focus for research
Journal Article