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Pandemic preparedness necessitates a multifaceted approach that emphasizes societal factors, such as building trust and acknowledges cultural and societal differences, with a focus on protecting vulnerable groups. To support these goals, the European Global Health Research Institutes Network has outlined a comprehensive transdisciplinary approach through a set of multilevel recommendations.

Correction: BMC Health Services Research 24, 1561 (2024) https://doi.org/10.1186/s12913-024-12104-7 In this article, an error in the author names of all authors was identified. Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität, Leopoldstr. 5, 80802, Munich, Germany Guenter Froeschl 11. Anne‑Mieke Vandamme1,12 Show authors BMC Health Services Research volume 25, Article number: 963 (2025) Cite this article The Original Article was published on 18 December 2024 Correction: BMC Health Services Research 24, 1561 (2024) https://doi.org/10.1186/s12913-024-12104-7 In this article, an error in the author names of all authors was identified.

The Large Yield Radiometer (LYRA) is an XUV–EUV–MUV (soft X-ray to mid-ultraviolet) solar radiometer onboard the European Space Agency Project for On-Board Autonomy 2 (PROBA2) mission, which was launched in November 2009. LYRA acquires solar-irradiance measurements at a high cadence (nominally 20 Hz) in four broad spectral channels, from soft X-ray to MUV, which have been chosen for their relevance to solar physics, space weather, and aeronomy. We briefly review the design of the instrument, give an overview of the data products distributed through the instrument website, and describe how the data are calibrated. We also briefly present a summary of the main fields of research currently under investigation by the LYRA consortium.

Age-related changes in gastrointestinal function have been reported in companion animals, but the impact on digestive efficiency remains uncertain. Healthy dogs (n = 37; 2.6–14.2 years) received four diets varying in total dietary fibre (TDF; 6–29%, as fed). Healthy cats (n = 28; 1–13 years) received four diets with two fat (10–12%; 17–18%) and TDF (9 and 12%) levels. In a crossover design, diets were provided over four consecutive 10-day cycles, including a 4-day faecal collection. Apparent crude protein (CP), ether extract (EE), TDF, calcium (Ca), and phosphorus (P) digestibilities were determined. The effect of age was analysed as a continuous variable in dogs and as differences between adult (1–5 years) and senior (7–13 years) cats. In dogs, EE digestibility was unaffected by age (p > 0.10). Dogs of 6–12 years had higher digestibility of CP (p = 0.032), TDF (p = 0.019), Ca (p = 0.019), and P (p = 0.024) when fed the 6% TDF diet. Senior cats had greater digestibility of TDF (p < 0.01) and Ca (p = 0.024) but had lower EE and CP digestibility with one diet (17% fat; 9%TDF) (age, p > 0.10; diet × age, p < 0.001). Healthy ageing was associated with preserved nutrient digestibility in dogs and cats within the age ranges studied. The effect of ingredient sources in senior cats warrants further investigation.

The implications of long-term high calcium (Ca) intake are well documented in growing dogs and in adult dogs of large breed size, however, the consequences on other breeds and breed sizes are yet to be determined. Eighteen neutered adult beagles, nine males and nine females aged 1.4–4.4 years, were randomized to control or test diets providing in g∙4184 kJ−1 (1000 kcal−1): 1.44 and 7.19 total Ca balanced with 1.05 and 4.25 total phosphorus, respectively, for 40 weeks. Health parameters, ultrasound scans, radiographs, glomerular filtration rate, and mineral balance were measured at eight-week intervals. All dogs remained healthy with no measured evidence of orthopedic, urinary, or renal disease. The test diet resulted in a 5.2 fold increase in fecal Ca excretion. Apparent Ca digestibility (%) and Ca balance (g/d) did not significantly (p > 0.05) change from baseline in the test diet group, although dogs displayed a positive Ca balance (maximum at week 8, 1.11 g/d with 95% CI (0.41, 1.80)) before a neutral Ca balance was restored at week 32. Despite an initial positive Ca balance, we can conclude that no measurable adverse health effects were observed as a result of the test diet fed in this study in beagles over a period of 40 weeks.

Diffuse plane normolipaemic xanthomatosis is a well-defined uncommon condition characterized by yellow-orange plaques involving the eyelids, neck, upper trunk, buttocks and flexural folds. Over half of the reported cases are associated with lymphoproliferative disorders. The condition may arise as a result of perivascular deposition of lipoprotein-immunoglobulin complexes. We present a female patient with clear clinical features of diffuse plane xanthomatosis associated with chronic lymphatic leukaemia and monoclonal gammopathy. In this patient, we found evidence of complement consumption supporting the hypothesis that complexes of lipoprotein and paraprotein are formed. Lipid electrophoresis of fasting serum revealed the presence of a faint precipitate at the application slot, also indicative of the presence of protein-lipid complexes.

Bullous pyoderma gangrenosum is an atypical, more superficial variety of the classical pyoderma and is often associated with myeloproliferative disorders. We present the case of a patient who presented initially with subcutaneous nodules and who developed bullous lesions afterwards. Histological evaluation showed the presence of neutrophilic infiltrates in both lesions. A few months after the diagnosis of bullous pyoderma gangrenosum, an underlying leukemia was revealed. Our case illustrates the importance of regular blood and bone marrow examinations in patients with atypical bullous pyoderma gangrenosum, resulting in a rapid diagnosis of the underlying disease.

McIntyre et al report severe cases of hand, foot, and mouth disease (HFMD) associated with coxsackievirus A6 in the states of Alabama, Connecticut, California, and Nevada during the period from Nov 2011 to Feb 2012. Of the 63 patients, 44 had exposure to a child care facility or school, and eight of the 15 adults had contact with children in child care where cases of HFMD were reported, or provided medical care or were related to a child with HFMD. Signs of HFMD included fever; rash on the hands or feet, or in the mouth; and rash on the arms or legs, buttocks, and trunk. HFMD is spread from person to person by contact with saliva, respiratory secretions, fluid in vesicles, and feces.