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result(s) for
"Sundas, Ali"
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Testing the national identity argument
2014
The national identity argument holds that a shared national identity is necessary to motivate citizens in democratic societies to pursue a number of goals, especially social justice. We review the empirical evidence for and against this claim, looking particularly at how national identities have been measured. We distinguish between studies that aim to compare the relative strength of identities cross-nationally and those that look at individual differences within one nation. We separate four dimensions of national identity: national attachment, national pride, critical vs. uncritical patriotism, and civic vs. cultural conceptions of identity. These are only weakly correlated with each other, and impact differently on support for social justice and the welfare state. Using case studies from the United States, Canada, and the United Kingdom, we suggest that the relationship between national identity and social justice varies between societies, and that a key factor is finding an appropriate balance between the strength of such identities and their inclusiveness.
Journal Article
UV-light-driven cadmium sulphide (CdS) nanocatalysts: synthesis, characterization, therapeutic and environmental applications; kinetics and thermodynamic study of photocatalytic degradation of Eosin B and Methyl Green dyes
by
Ali, Sundas
,
Akbar Jan, F.
,
Ullah, Rahat
in
Analysis
,
Analytical methods
,
Antibacterial activity
2022
Cadmium sulphide (CdS) nanoparticles (NPs) were synthesized through hydrothermal route and characterized by UV-Vis spectroscopy, X-ray diffraction (XRD), Energy dispersive X-ray analysis, Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy and Thermo gravimetric analysis (TGA).The band gap of CdS nanoparticles was found to be 2.38 eV. CdS NPs are crystalline aggregates with hexagonal structure as shown by SEM and XRD analysis. TGA study revealed that the synthesized nanomaterials were very stable to temperature and only 6.54% total loss occurred during heating range (25 °C–600 °C).The CdS NPs were used for the first time against the degradation of Eosin B (EB) and Methyl green (MG) dyes in aqueous solution.The degradation of EB and MG over CdS nanocatalysts followed second order kinetics. The predicted activation energies for both the dyes' reactions were 61.1 kJ/mol and 32.11 kJ/mol, respectively. About 95% and 90% dye degradation was observed at the time interval of 160 minutes for EB and MG, respectively. High percent degradation of EB was observed at high pH (pH 0) while at low pH (pH 4) high percent degradation was found for MG dye. Maximum dye degradation was found at the optimal dose (0.03 g/L) of the catalyst and at low dye concentration. The rate of EB and MG dye degradation was found to increase with increase in temperature up to 45 °C. The recyclability study showed that CdS nanoparticles could be reused for the degradation of the given dyes. Good antibacterial activity against Staphylococcus aureus was shown by CdS NPs. From the biocompatibility it was confirmed that CdS NPS are bioincompatible compatible.
Journal Article
Incidental Pulmonary Nodule (IPN) Programs Working Together with Lung Cancer Screening and Artificial Intelligence to Increase Lung Cancer Detection
by
Alvarez-Pinzon, Andres M.
,
Purohit, Luv
,
Kiamos, Amy
in
Artificial intelligence
,
Cancer
,
Cancer screening
2025
Current lung cancer screening guidelines in the United States fail to identify many individuals at risk of developing the disease. Additionally, existing healthcare infrastructure has been leveraged to establish IPN clinics, a promising approach to addressing the limitations of current screening guidelines. Early-stage lung cancer is frequently diagnosed because of the incidental detection of pulmonary nodules on clinically indicated chest CT scans, particularly in the absence of formal screening programs. While artificial intelligence (AI) systems for lung cancer detection have demonstrated significant advancements in medicine, their clinical validation in screening settings remains limited. This review will discuss the pivotal trials underpinning the United States Preventive Services Task Force (USPSTF) recommendations for lung cancer screening, which have shaped the current guidelines for at-risk populations. We will explore recent studies investigating the role of AI in enhancing lung cancer screening efforts, highlighting how AI has the potential to improve early detection, streamline workflows, and reduce false positives and negatives in screening processes. This review will present the lung cancer screening rates at our institution, with a specific focus on the validation and integration of AI-driven technologies into our established screening programs. Using AI algorithms, we have validated enhanced detection capabilities through retrospective analysis of historical patient data, demonstrating significant improvements in identifying high-risk individuals and early-stage malignancies. These AI models, validated through rigorous cross-validation methods and clinical trials, have proven to outperform traditional screening approaches in sensitivity and specificity. The integration of these AI technologies within the lung cancer screening framework not only optimizes existing programs but also expands access to screening, improving early detection rates and ultimately leading to better patient outcomes. Through continuous validation and refinement, we aim to solidify AI’s role in transforming lung cancer detection and patient care. Through ongoing validation and implementation, AI can play a crucial role in transforming lung cancer screening practices, ultimately contributing to earlier diagnosis and improved patient survival.
Journal Article
Correction: Purohit et al. Incidental Pulmonary Nodule (IPN) Programs Working Together with Lung Cancer Screening and Artificial Intelligence to Increase Lung Cancer Detection. Cancers 2025, 17, 1143
by
Alvarez-Pinzon, Andres M.
,
Purohit, Luv
,
Kiamos, Amy
in
Artificial intelligence
,
Cancer
,
Diagnosis
2025
There was an error in the original publication [...]
Journal Article
Clinical Response of Meropenem versus Meropenem and Azithromycin in Extensively Drug-Resistant Salmonella
by
Muhammad Ameen
,
Ali, Sundus
,
Siddiqi, Ayesha
in
Antibiotics
,
Azithromycin
,
Combination therapy
2024
Objectives: To compare the clinical response of Meropenem versus a combination of Meropenem and Azithromycin in Extensively Drug-Resistant Salmonella. Study Design: Quasi-experimental study. Place and Duration of Study: Tertiary Care Hospital, Malir Pakistan, from Mar to Sep 2023. Methodology: A total of 100 patients (50 in the Meropenem group and 50 in the Meropenem and Azithromycin group) who were diagnosed with typhoid fever secondary to extensively drug-resistant salmonella were included. The duration of hospital stay, post-therapy C-reactive protein, time for defervescence, and complete clinical response were compared between the groups. Results: Median age was 29(49–16) years. There were 78(78%) males and 22(22%) females. Median weight of patients was 75(90–55) kg. Median duration of fever was 6(14–1) days. Median baseline C-reactive protein was 44(167–13) mg/dl. Complete clinical response in Meropenem alone group 49(98%) was significantly higher as compared to Meropenem + Azithromycin group 38(76%), (p=0.001). Similarly, duration of hospital stay and time to defervescence were also significantly shorter in the Meropenem alone group (p<0.001). Conclusion: Meropenem alone is better than the combination of Meropenem + Azithromycin, with a shorter hospital stay, lesser time to defervescence, and better clinical response.
Journal Article
Allogeneic hematopoietic stem cell transplant in rare hematologic disorders: a single center experience from Pakistan
by
Raheel, Iftikhar
,
Hussain Fayyaz
,
Chaudhry Qamar un Nisa
in
Bleeding
,
Bone marrow
,
Conditioning
2021
Management of rare hematological disorders pose unique diagnostic and therapeutic challenges due to unusual occurrence and limited treatment options. We retrospectively identified 45 patients receiving matched related donor transplant for rare hematological disorders from 2006 to 2019. Patients were divided into two groups (1) malignant and (2) non malignant. The malignant disorder group included four patients while the nonmalignant group included 41 patients divided into immune dysregulation (n = 23), bone marrow failure (n = 10), metabolic (n = 5), and bleeding diathesis (n = 3). Twenty-six (57.8%) patients received myeloablative conditioning (MAC) and 16 (35.6%) received reduced intensity conditioning (RIC), while 3 (6.6%) patients with severe combined immunodeficiency received stem cell infusion alone without conditioning. The cumulative incidence (CI) of grade II–IV acute GVHD (aGVHD) was 39.1% (n = 18) and chronic GVHD (cGVHD) 15.2% (n = 7). There was no primary graft failure while CI of secondary graft failure was 9%. Overall survival (OS) and disease-free survival (DFS) was 82.2% and 77.8% respectively. Group wise OS was 75% in the malignant group, 82.6% in the immune dysregulation group, 80% in patients with metabolic disorders and bone marrow failure, while 100% in patients with bleeding diathesis. This retrospective analysis shows that hematopoietic stem cell transplant can be a feasible treatment option for rare hematological disorders.
Journal Article
Dural Venous Sinus Thrombosis Leading to Subarachnoid Hemorrhage
2021
Dural venous sinus thrombosis (DVST) leading to subarachnoid hemorrhage (SAH) is rarely reported in the literature. A 25-year-old primigravida with a history of pre-eclampsia presented with sudden onset headache, confusion, and loss of consciousness. Examination revealed bilateral equivocal planters and bilateral papillary edema. MRI and magnetic resonance venography (MRV) showed the right sinus thrombosis with elements of SAH. The coagulation profile was unremarkable. She was commenced on low molecular weight heparin with periodic monitoring of her Glasgow Coma Scale (GCS). Her condition started improving gradually. Repeat MRI and MRV after 10 days showed resolution of thrombosis and SAH. She was discharged with follow-up, and she was doing well on her recent visit two weeks later.
Journal Article
Who speaks for Muslims? The role of the press in the creation and reporting of Muslim public opinion polls in the aftermath of London bombings in July 2005
2015
Muslim public opinion polls are mostly taken at face value as the direct and unbiased voice of British Muslims, but, as this article argues, most of the public opinion polls are commissioned by the media and suffer from similar framing effects to those seen in the general media coverage of Muslims. At a time of national crisis, following the London terrorist attacks in 2005, it has become especially clear that the media have been following their pre-existing narrative on Muslims rather than responding to public interest. We analyse all public opinion polls conducted in the 18 months following the 7 July attacks and all their broadsheet newspaper coverage to show that the media-framing effects influence both the creation of Muslim opinion polls and their reporting.
Journal Article
Kawasaki Disease-Like Features in 10 Pediatric COVID-19 Cases: A Retrospective Study
by
Khalid, Farhan
,
Jaan, Ali
,
Falah, Noor Ul
in
Infectious Disease
,
Internal Medicine
,
Pediatrics
2020
Children with coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), usually present with symptoms of mild upper respiratory tract infection without developing any significant complications. However, this observation has been rendered incautious by hundreds of clinical cases from around the world that have depicted a less benign multisystem inflammatory illness mimicking Kawasaki disease in COVID-positive pediatric patients. Our study aimed at retrospectively reviewing the different features of Kawasaki disease-like illness in children suffering from COVID-19, including the complications, laboratory investigations, treatment strategies used during their hospital stay, and outcomes. We searched the electronic database of the two pediatric units of Mayo Hospital, Lahore, Pakistan, for children who had been admitted to the ward between April 2020 and July 2020 and were diagnosed with COVID-19. A total of 10 such pediatric cases were found, whose clinical details were then reviewed and the obtained data were presented in the form of tables and percentages. The median age was between 4 months to 11 years (mean: 6 years). Of the 10 patients, 8 (80%) were boys. Criteria for Kawasaki disease were met in all of them (100%), with a complete presentation in five (50%). Fever (100%), conjunctival and oral cavity changes (90%), and rash (80%) were the most common features. Seven (70%) patients required admission to a critical care unit, but no mortality occurred. This article can assist in understanding and dealing with Kawasaki disease-like manifestation of pediatric COVID-19 infection, especially in critical care settings, and its possible complications. It will help in a timely and appropriate decision-making regarding treatment and management of such cases.Children with coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), usually present with symptoms of mild upper respiratory tract infection without developing any significant complications. However, this observation has been rendered incautious by hundreds of clinical cases from around the world that have depicted a less benign multisystem inflammatory illness mimicking Kawasaki disease in COVID-positive pediatric patients. Our study aimed at retrospectively reviewing the different features of Kawasaki disease-like illness in children suffering from COVID-19, including the complications, laboratory investigations, treatment strategies used during their hospital stay, and outcomes. We searched the electronic database of the two pediatric units of Mayo Hospital, Lahore, Pakistan, for children who had been admitted to the ward between April 2020 and July 2020 and were diagnosed with COVID-19. A total of 10 such pediatric cases were found, whose clinical details were then reviewed and the obtained data were presented in the form of tables and percentages. The median age was between 4 months to 11 years (mean: 6 years). Of the 10 patients, 8 (80%) were boys. Criteria for Kawasaki disease were met in all of them (100%), with a complete presentation in five (50%). Fever (100%), conjunctival and oral cavity changes (90%), and rash (80%) were the most common features. Seven (70%) patients required admission to a critical care unit, but no mortality occurred. This article can assist in understanding and dealing with Kawasaki disease-like manifestation of pediatric COVID-19 infection, especially in critical care settings, and its possible complications. It will help in a timely and appropriate decision-making regarding treatment and management of such cases.
Journal Article
A Rare Case of Bertolotti's Syndrome in a Young Patient: A Case Report and Literature Review
by
Kumar, Jasvindar
,
Singh, Manjeet
,
Ali, Sundas
in
Internal Medicine
,
Orthopedics
,
Physical Medicine & Rehabilitation
2020
Bertolotti's syndrome is a congenital condition characterized by the sacralization of the lower lumbar vertebrae or the lumbarization of the sacral vertebrae. The cause of pain in Bertolotti's syndrome is multifactorial. This lumbosacral transitional vertebra has a prevalence of 4% to 30%. Rarely, it is considered in the differential diagnosis of low back pain in young people. Therefore, every aspect of Bertolotti's syndrome needs to be meticulously addressed, and it should be included in the differential diagnosis of chronic back pain. Herein, we present a case of Bertolotti's syndrome presented with chronic lower back pain, confirmed on X-ray and magnetic resonance imaging (MRI). He was managed with analgesics and steroids injection with regular follow-up.Bertolotti's syndrome is a congenital condition characterized by the sacralization of the lower lumbar vertebrae or the lumbarization of the sacral vertebrae. The cause of pain in Bertolotti's syndrome is multifactorial. This lumbosacral transitional vertebra has a prevalence of 4% to 30%. Rarely, it is considered in the differential diagnosis of low back pain in young people. Therefore, every aspect of Bertolotti's syndrome needs to be meticulously addressed, and it should be included in the differential diagnosis of chronic back pain. Herein, we present a case of Bertolotti's syndrome presented with chronic lower back pain, confirmed on X-ray and magnetic resonance imaging (MRI). He was managed with analgesics and steroids injection with regular follow-up.
Journal Article