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The current work is mainly devoted to the synthesis, structural, electrical, and magnetic characterization of Sr 1−X La X Fe 12 O 19 (X = 0.2–0.8) (SLFO) nanoparticles synthesized via the hydrothermal technique. The hexagonal peaks were determined using X-ray diffraction analysis. The obtained results indicated that the lattice constants were noted to be increasing from 0.58801 to 0.58825 nm (a = b), and 2.30309 to 2.30341 nm (c) with increase of in ‘X’. The morphological studies ensured that the grains as well as nanoparticles of SLFO acquired almost spherical shape. The optical properties were investigated using FTIR and UV–Visible spectra. The optical bandgap (E g ) of SLFO was found to be increasing from 1.866 to 2.118 eV with increase of dopant content. The electrical properties of SLFO were studied in detail as a function of temperature, and frequency. In addition, the dielectric modulus, and impedance spectroscopy analysis was carried out to describe the space charge polarization, and electric conduction mechanism, respectively. The hysteresis loop (M–H curves) of SLFO revealed the decrease of magnetization from 36.34 to 7.17 emu/g with increase in ‘X’.

Background & objectives India has the second highest number of adults with diabetes in the world, and more than one-fourth of adults have hypertension. This article describes the preparedness of public and private health facilities for type 2 diabetes mellitus and hypertension management. Methods A cross-sectional survey of the health facilities was conducted in 19 districts of seven States in India, which included an assessment of both public and private health facilities. We used the Indian Public Health Standards and other relevant guidelines for assessment. The service domain score for four domains: equipment, medicine, diagnostics capacity, staff, including the availability of guidelines, and overall readiness score, was calculated following the Service Availability and Readiness Assessment manual of the World Health Organisation. The study considered a readiness score of ≥70 per cent to classify a facility as prepared for providing hypertension and diabetes services. Results Out of 415 health facilities covered in the survey, 75.7 per cent were public facilities. Most were primary care facilities (57.6%) and were located in rural areas (53.3%). The overall readiness score for providing hypertension and diabetes services was lowest for Sub-Centres (SCs; 61%) and Community Health Centres (CHCs; 59%), compared to other facilities. The readiness score for public Primary Health Centres (PHCs) and private primary care facilities (level 2) was 73 and 57 per cent, respectively. The readiness score of district hospitals, government private medical colleges, and other private tertiary care facilities was above 70 per cent, and they were considered prepared for services. Interpretations & conclusions PHCs were better prepared for diabetes and hypertension care than SCs, CHCs, and SDHs. By ensuring adequate human resources availability and uninterrupted supply of essential medicines, programme managers can further improve the preparedness of all public health facilities.

The advent of Industry 4.0 has opened a data-rich avenue of predicting and controlling premature degradation of industrial materials. For any industrial construction or manufacturing projects, performing analysis on the structural integrity of materials is crucial for their sustainability. Corrosion Science: Modern Trends and Applications gives scholars a snapshot of recent contributions and development in the field of material corrosion.The book presents 12 chapters that cover topics such as corrosion testing methods, anti-corrosive coating mechanisms, corrosion in different types of products (electronics, polymers), industrial systems (power plants, concrete constructions and hydraulic systems) and corrosion as a result of environmental characteristics (such as marine surroundings). The breadth of topics covered coupled with the reader-friendly presentation of the book make it highly beneficial for students, research scholars, faculty members and R&D specialists working in the area of corrosion science, material science, solid-state science, chemical engineering, and nanotechnology. Readers will be equipped with the knowledge to understand and plan industrial processes that involve measuring the reliability and integrity of material structures which are impacted by corrosive factors.

Maternal alcohol exposure during pregnancy can substantially impact the development of the fetus, causing a range of symptoms, known as fetal alcohol spectrum disorders (FASDs), such as cognitive dysfunction and psychiatric disorders, with the pathophysiology and mechanisms largely unknown. Recently developed human cerebral organoids from induced pluripotent stem cells are similar to fetal brains in the aspects of development and structure. These models allow more relevant in vitro systems to be developed for studying FASDs than animal models. Modeling binge drinking using human cerebral organoids, we sought to quantify the downstream toxic effects of alcohol (ethanol) on neural pathology phenotypes and signaling pathways within the organoids. The results revealed that alcohol exposure resulted in unhealthy organoids at cellular, subcellular, bioenergetic metabolism, and gene expression levels. Alcohol induced apoptosis on organoids. The apoptotic effects of alcohol on the organoids depended on the alcohol concentration and varied between cell types. Specifically, neurons were more vulnerable to alcohol-induced apoptosis than astrocytes. The alcohol-treated organoids exhibit ultrastructural changes such as disruption of mitochondria cristae, decreased intensity of mitochondrial matrix, and disorganized cytoskeleton. Alcohol exposure also resulted in mitochondrial dysfunction and metabolic stress in the organoids as evidenced by (1) decreased mitochondrial oxygen consumption rates being linked to basal respiration, ATP production, proton leak, maximal respiration and spare respiratory capacity, and (2) increase of non-mitochondrial respiration in alcohol-treated organoids compared with control groups. Furthermore, we found that alcohol treatment affected the expression of 199 genes out of 17,195 genes analyzed. Bioinformatic analyses showed the association of these dysregulated genes with 37 pathways related to clinically relevant pathologies such as psychiatric disorders, behavior, nervous system development and function, organismal injury and abnormalities, and cellular development. Notably, 187 of these genes are critically involved in neurodevelopment, and/or implicated in nervous system physiology and neurodegeneration. Furthermore, the identified genes are key regulators of multiple pathways linked in networks. This study extends for the first time animal models of binge drinking-related FASDs to a human model, allowing in-depth analyses of neurotoxicity at tissue, cellular, subcellular, metabolism, and gene levels. Hereby, we provide novel insights into alcohol-induced pathologic phenotypes, cell type-specific vulnerability, and affected signaling pathways and molecular networks, that can contribute to a better understanding of the developmental neurotoxic effects of binge drinking during pregnancy.

The present work focussed on the preparation and characterization of AlxLa1−xTiO3 (x = 0.2–0.8) (ALTO) nanospheres. The phase purity and tetragonal structure was confirmed using the X-ray diffraction patterns. In addition, the dimensions of the ALTO unit cell were decreased with increase of Al-content. The morphological investigations evidenced the formation of spherical grains and particles of nano size. The UV–Visible spectra revealed the increasing trend of band gap (Eg) from 3.341 to 3.378 eV as a function ‘x’. Besides, the frequency, and compositional variation of dielectric parameters was described. Subsequently, the space charge polarization, and electrical conduction mechanisms were well understood using the complex dielectric modulus, and impedance spectroscopy. The Cole–Cole plots ensured that the ALTO materials exhibited the semiconducting nature due to the formation of complete semicircular arcs. Moreover, the non-Debye type relaxations were noticed in Cole–Cole plots.

Metamaterials are the major type of artificially engineered materials which exhibit naturally unobtainable properties according to how their microarchitectures are engineered. Owing to their unique and controllable effective properties, including electric permittivity and magnetic permeability, the metamaterials play a vital role in the development of meta-devices. Therefore, the recent research has mainly focused on shifting towards achieving tunable, switchable, nonlinear, and sensing functionalities. In this review, we summarize the recent progress in terahertz, microwave electromagnetic, and photonic metamaterials, and their applications. The review also encompasses the role of metamaterials in the advancement of microwave sensors, photonic devices, antennas, energy harvesting, and superconducting quantum interference devices (SQUIDs).

The advancement of the Internet of Things (IoT) has tremendously influenced many fields of human life. The Internet of Medical Things, Internet of Flying Things, Internet of Floating Things and Internet of Autonomous Things are recent evolution of IoT. The protocols used in all forms of IoT are critical during the execution demanding formal verification methods to ensure correctness. However, the most challenging part of formal verification is abstracting the system under test, making many systems unverified. Formal protocol verification is essential for detecting specification and design flaws that go undetected and corrected during the testing phase. This paper proposes novel methods for abstracting communication patterns for IoT protocols. Message broadcasts, periodic message advertisements, topology encoding, and topology change are examples of communication patterns. An attempt is made to model these patterns using pi -calculus and PROMELA. Finally, the trickle, a wireless sensor network dissemination protocol, has been modelled using pi -calculus and PROMELA. The Spin model checker verifies design flaws, such as deadlocks and non-progress cycles. The verification results ensure that there are no deadlocks or non-progress loops. The protocol is statically verified for message transmission semantics. The analysis revealed that the protocol could only guarantee message transmission for lossy connections if an alternative route covers all other nodes. The empirical results and theorem show that the abstraction mechanism can be directly utilised for automated and theoretical verification. Researchers can use the abstraction framework described in this paper to create validation models for static and automated verification of existing and new IoT protocols.

Recent observations of surface meteorology and exchanges of heat, freshwater, and momentum between the ocean and the atmosphere in the Bay of Bengal are presented. These observations characterize air-sea interaction at 18°N, 89.5°E from December 2014 to January 2016 and also at other locations in the northern Bay of Bengal. Monsoonal variability dominated the records, with winds to the northeast in summer and to the southwest in winter. This variability included a strong annual cycle in the atmospheric forcing of the ocean in the Bay of Bengal, with the winter monsoon marked by sustained ocean heat loss resulting in ocean cooling, and the summer monsoon marked by strong storm events with dark skies and rain that also resulted in ocean cooling. The spring intermonsoon was a period of clear skies and low winds, when strong solar heating and weak wind-driven mixing led to ocean warming. The fall intermonsoon was a transitional period, with some storm events but also with enough clear skies and sunlight that ocean surface temperature rose again. Mooring and shipboard observations are used to examine the ability of model-based surface fluxes to represent air-sea interaction in the Bay of Bengal; the model-based fluxes have significant errors. The surface forcing observed at 18°N is also used together with a one-dimensional ocean model to illustrate the potential for local air-sea interaction to drive upper-ocean variability in the Bay of Bengal.

The lead cobalt titanate (PCT) nanoparticles were prepared by sol–gel method and further microwave heated at 1023 K for 3/4 h. The X-ray diffraction pattern revealed the formation of PCT phases. The average crystallite-size was acquired to be 26.3 nm. The surface morphology of specimen was analyzed using transmission electron microscope. The ferroelectric property was elucidated by means of polarization versus electric field loop as a function of temperature.