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2 result(s) for "Swain, Pragyna Parimita"
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Measurement, processing and analysis of stress magnetocardiograms
Magnetocardiography (MCG) measures weak magnetic fields originating due to the electrical activity of the heart. MCG offers distinct diagnostic information on the cardiac electrophysiology in a variety of dysfunctions. This list includes myocardial ischemia, which is associated with reduced blood supply to the heart, electrically manifested as changes in the ST segment of the cardiac cycle. As opposed to the conventional measurement of electrocardiogram (ECG) on subjects undergoing physical stress test to investigate these ST changes, rest MCG itself has been demonstrated to be more sensitive. Considerable interest exists among researchers to investigate MCG signals measured during physical exertion as well to explore the possibilities of improvements in its sensitivity. This paper portrays the MCG measurements of a few subjects under rest and during moderate cycling in supine posture using a non-magnetic bicycle ergometer. The work details the signal processing steps followed in processing MCG to refine the signal quality in computing the parameter, ST fluctuation score in an automated manner. Significant changes are seen on the ST fluctuation scores measured on a few healthy subjects across rest and stress conditions. These results persuade its possible use on MCG measured on subjects with ischemic heart diseases by treating this analysis as baseline measurements.
Magnetocardiography for identification of coronary ischemia in patients with chest pain and normal resting 12‐lead electrocardiogram
Background Identification of coronary ischemia in patients presenting with chronic chest pain is difficult as resting ECG can be normal. Diagnosis of coronary ischemia requires evaluation during exercise or pharmacological stress. A noninvasive test to identify coronary ischemia at rest without the need for exercise is desirable. We studied the diagnostic accuracy of magnetocardiography (MCG) at rest to detect coronary ischemia in these patients. Methods Patients with chronic chest pain and suspected coronary ischemia with a normal ECG were included. Patients underwent treadmill test (TMT) and were divided into TMT positive and TMT negative groups. MCG was recorded in a magnetically shielded room. Iso‐field contour maps generated at the T‐wave peak were compared between the groups. From the magnetic field map (MFM), the magnetic field angle at T‐wave peak was calculated and was also compared across the two groups. Results There were a total of 29 patients, 12 with positive TMT and 17 with negative TMT. An abnormal magnetic field angle was more common in the TMT positive group (72% vs. 6%). Abnormal contour maps in the form of nondipole patterns or abnormal orientation were seen in 81.8% (9/11) patients in TMT positive group and 6.8% (1/17) patients in the TMT negative group (p < .001). Conclusion Abnormal magnetic field angle and abnormal magnetic field maps in MCG recorded at rest are able to identify the presence of coronary ischemia in patients with chronic chest pain and a normal resting ECG.