Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
10,175
result(s) for
"Tan, Lu"
Sort by:
Sarong party girls
On the edge of twenty-seven, Jazzy hatches a plan for her and her best girlfriends: Sher, Imo, and Fann. Before the year is out, these Sarong Party Girls will all have spectacular weddings to expat ang moh-- caucasian-- husbands, with Chanel babies (half-white children--the ultimate status symbol) quickly to follow. Razor-sharp, spunky, and cheerfully brand-obsessed, Jazzy is a woman who plays to win. As she fervently pursues her quest to find the right husband, this driven yet tenderly vulnerable gold digger reveals the contentious gender politics and class tensions thrumming beneath the shiny exterior of Singapore's glamorous nightclubs and busy streets, its grubby wet markets and crowded hawker centers. Moving through her colorful, stratified world, she realizes she cannot ignore the troubling incongruity of new money and old-world attitudes that threatens to crush her dreams. Can Jazzy use her cunning and good looks to rise up the ladder in Asia's international capital? Vividly told in Singlish-- colorful Singaporean English with its distinctive cadence and slang-- Sarong Party Girls brilliantly captures the unique voice of this young, striving woman caught between worlds. With remarkable vibrancy and empathy, Cheryl Lu-Lien Tan brings not only Jazzy, but her city of Singapore, to dazzling, dizzying life.--Page 2 of cover.
Book
Measurements of global and local spin polarization of hyperons in Au+Au collisions at RHIC-STAR
Vortical structure created in heavy ion collision leads to the polarization of hyperons phenomenon, which can be used as a probe to study the spin degree of freedom. RHIC Beam Energy Scan II program offers a good opportunity to study the hyperon polarization over the wide energy regime. In these proceedings, we report measurements of the global polarization of Λ, Λ ̅, Ξ ± and Ω ± at √ s NN = 7.7−27 GeV in Au+Au collisions from BES-II. The global hyperons polarization of all hyperons decrease as collision energy increases. Additionally, we report the second harmonics of local Λ, Λ ̅ polarization and their difference at √ sNN = 7.7−27 GeV, which can be used to probe the baryonic spin Hall effect. These measurements provide valuable insights into the spin dynamics within the QCD medium produced in heavy ion collisions.
Journal Article
Comparison of RetinaNet, SSD, and YOLO v3 for real-time pill identification
Background
The correct identification of pills is very important to ensure the safe administration of drugs to patients. Here, we use three current mainstream object detection models, namely RetinaNet, Single Shot Multi-Box Detector (SSD), and You Only Look Once v3(YOLO v3), to identify pills and compare the associated performance.
Methods
In this paper, we introduce the basic principles of three object detection models. We trained each algorithm on a pill image dataset and analyzed the performance of the three models to determine the best pill recognition model. The models were then used to detect difficult samples and we compared the results.
Results
The mean average precision (MAP) of RetinaNet reached 82.89%, but the frames per second (FPS) is only one third of YOLO v3, which makes it difficult to achieve real-time performance. SSD does not perform as well on the indicators of MAP and FPS. Although the MAP of YOLO v3 is slightly lower than the others (80.69%), it has a significant advantage in terms of detection speed. YOLO v3 also performed better when tasked with hard sample detection, and therefore the model is more suitable for deployment in hospital equipment.
Conclusion
Our study reveals that object detection can be applied for real-time pill identification in a hospital pharmacy, and YOLO v3 exhibits an advantage in detection speed while maintaining a satisfactory MAP.
Journal Article
Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification
There is strong evidence that obesity is a risk factor for poor semen quality. However, the effects of multigenerational paternal obesity on the susceptibility to cadmium (a reproductive toxicant)-induced spermatogenesis disorders in offspring remain unknown. Here, we show that, in mice, spermatogenesis and retinoic acid levels become progressively lower as the number of generations exposed to a high-fat diet increase. Furthermore, exposing several generations of mice to a high fat diet results in a decrease in the expression of Wt1, a transcription factor upstream of the enzymes that synthesize retinoic acid. These effects can be rescued by injecting adeno-associated virus 9-
Wt1
into the mouse testes of the offspring. Additionally, multigenerational paternal high-fat diet progressively increases METTL3 and
Wt1
N6-methyladenosine levels in the testes of offspring mice. Mechanistically, treating the fathers with STM2457, a METTL3 inhibitor, restores obesity-reduced sperm count, and decreases
Wt1
N6-methyladenosine level in the mouse testes of the offspring. A case-controlled study shows that human donors who are overweight or obese exhibit elevated N6-methyladenosine levels in sperm and decreased sperm concentration. Collectively, these results indicate that multigenerational paternal obesity enhances the susceptibility of the offspring to spermatogenesis disorders by increasing METTL3-mediated
Wt1
N6-methyladenosine modification.
The mechanisms through which multigenerational paternal obesity affects spermatogenesis in offspring remain poorly understood. Here, the authors show that it affects
Wt1
m6A modifications, decreasing the fertility of offspring.
Journal Article
“A sheep, a sheep” - Viral marketing packaged as a game
\"A sheep, a sheep\", is a recently popular mini game related to consumer goods. In terms of entertainment and classic gameplay, it cannot compare with many excellent works of the same type.With incomplete gameplay and superb operational methods, it has been lifted to a height that does not belong to it by netizens. This article attempts to discuss its viral marketing process and logic, as well as the industry causes and harms that cause this phenomenon, in order to decipher the key to the popularity of this phenomenal mini game.
Journal Article
A High-Efficiency Wireless Information and Energy Co-Transmission System Based on Self-Compensating Inductive Temperature Sensitivity Error
To address the stability issues of energy and information transmission in wireless power and information transfer system operating over a wide temperature range, this paper establishes a mathematical model of the resonant frequency of an electromagnetic coupling system under varying temperature conditions. Simulations and experiments are conducted to analyze the impact of temperature on resonance characteristics. The results show that within the temperature range of −40 °C to 50 °C, frequency deviation leads to a reduction in the power deviation coefficient to 35.93%. To mitigate this issue, a real-time frequency compensation method based on Direct Digital Synthesis (DDS) is proposed, which dynamically adjusts the operating frequency to ensure that the system remains in optimal resonance. The experimental results demonstrate that the proposed method reduces the system’s operating frequency error from 3 kHz to within 0.2 kHz (a 93.33% reduction), restoring the power deviation coefficient to 0.54% and significantly improving system stability and reliability. This study provides theoretical support and engineering insights for the optimization of electromagnetic coupling wireless power and the information transfer system under wide temperature conditions.
Journal Article
Immunomodulatory multifunctional janus collagen-based membrane for advanced bone regeneration
Guided bone regeneration (GBR) is a standard therapy for treating bone defects, with collagen-based barrier membranes widely used clinically. However, these membranes face challenges like poor mechanical properties, early bacterial invasion and immunomodulation deficiency, potentially risking GBR failure. Orchestrating macrophage activation and controlling their M1 or M2 polarization are effective strategies for bone repair. Here, we present a Janus collagen-based barrier membrane with immunomodulation. The porous layer promotes direct osteogenic differentiation and inward growth of osteoblasts. The dense layer prevents invasion of soft tissue into bone defects and protects bone defects from bacterial infection. The membrane also enhances rat bone marrow-derived mesenchymal stem cell infiltration, proliferation, and osteogenic differentiation by regulating the immune microenvironment, demonstrating superior bone regeneration compared to the commercial Bio-Gide® membrane. Overall, the Janus collagen-based membrane reduces tissue inflammation and fosters an osteoimmune environment conducive to new bone formation, offering effective material design for advanced GBR technology.
Guided bone regeneration (GBR) membranes are used to treat bone defects, but face challenges in regulating the immune microenvironment. Here, Yang et al. report a Janus collagen-based barrier membrane that modulates the osteoimmune microenvironment to effectively promote bone regeneration.
Journal Article
Research on model predictive control strategy of three-level dual-active bridge DC-DC converter
A model predictive control strategy for Zero Voltage Switching (ZVS) was proposed for the mid-point clamp three-level dual Active Bridge (DAB) DC-DC converter. Through the switching conduction mode of the three-level DAB converter, the working conditions of the inductor current in each mode are analyzed, and the range of zero-voltage turn-on of all switches of the three-level DAB under single phase shift (SPS) modulation is derived. The spatial equation of state is established according to each mode, the purpose of fast response is achieved through the cost function, and finally the predictive control strategy of the three-level DAB model with zero voltage turn-on is obtained discretically. Simulation results show that the output voltage of the control strategy can be quickly stabilized under the load mutation condition when the converter realizes the zero voltage opening of all open tubes, which not only reduces the loss of the switch tubes, but also makes the system have faster dynamic response ability.
Journal Article
Lipoxin A4 protects primary spinal cord neurons from Erastin‐induced ferroptosis by activating the Akt/Nrf2/HO‐1 signaling pathway
Ferroptosis is an iron‐dependent programmed cell death, which participates in the pathogenesis of spinal cord injury (SCI). Our previous study has revealed that Lipoxin A4 (LXA4) exerts a protective role in SCI. Here, we investigated whether LXA4 can protect SCI through inhibiting neuronal ferroptosis. We treated primary spinal cord neurons with Erastin (ferroptosis activator) to induce ferroptosis. Erastin treatment reduced cell viability and enhanced cell death of primary spinal cord neurons, which was rescued by ferrostatin‐1 (ferroptosis inhibitor). Moreover, Erastin repressed glutathione peroxidase 4 (GPX4) expression and the levels of glutathione and cysteine in primary spinal cord neurons. Erastin also enhanced the expression of ferroptosis biomarkers (PTGS2 and ACSL4) and the levels of reactive oxygen species (ROS) in primary spinal cord neurons. The influence conferred by Erastin was effectively abolished by LXA4 treatment. Furthermore, LXA4 enhanced the protein expression of p‐AKT, nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) and haem‐oxygenase‐1 (HO‐1) in primary spinal cord neurons. LXA4‐mediated inhibition of ferroptosis of primary spinal cord neurons was prohibited by LY294002 (AKT inhibitor), brusatol (Nrf2 inhibitor) or zinc protoporphyrin (HO‐1 inhibitor). In conclusion, this work demonstrated that LXA4 exerted a neuroprotective effect in Erastin‐induced ferroptosis of primary spinal cord neurons by activating the Akt/Nrf2/HO‐1 signaling pathway. Thus, this work provides novel insights into the mechanisms of action of LXA4 in ferroptosis of primary spinal cord neurons and indicates that LXA4 may be a potential therapeutic agent for SCI. Ferroptosis is closely associated with the pathogenesis of spinal cord injury. Erastin induced ferroptosis of primary spinal cord neurons, which was effectively abolished by Lipoxin A4 (LXA4) treatment. LXA4 exerted a neuroprotective effect in Erastin‐induced ferroptosis of primary spinal cord neurons by activating the Akt/nuclear factor (erythroid‐derived 2)‐like 2/haem‐oxygenase‐1 signaling pathway. Thus, LXA4 may be a potential therapeutic agent for spinal cord injury.
Journal Article
Recent Progress in Antimatter Research with Heavy-Ion Collisions
Matter–antimatter asymmetry is a fundamental question in both astronomy and particle physics. Investigating antimatter is of great interest for testing the potential explanations of matter–antimatter asymmetry in our Universe. In relativistic heavy-ion collisions, the extremely high energy density and temperature are similar to the early Universe shortly after the Big Bang. In this paper, we review the recent progress in antimatter search and study heavy-ion collisions, with a focus on the RHIC-STAR and LHC-ALICE experiments, particularly the newly observed antimatter hypernuclei H¯Λ¯4 and He¯Λ¯4. The statistical thermal model and the coalescence production model can quantitatively describe the production yields and yield ratios, and the yield measurements of H¯Λ¯4, He¯Λ¯4 and their matter counterparts indicate the existence of spin-excited states of these (anti)hypernuclei. Furthermore, new measurements of the lifetimes of H¯Λ¯3, H¯Λ¯4 and their matter counterparts reveal no difference between a particle and its corresponding antiparticle, which validates the CPT theorem.
Journal Article