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This article presents excerpts from a master’s dissertation in Performing Arts about performances of children’s playing bodies, in Early Childhood Education, based on the Orixás universe. It initially reveals the participating children (NEI/Cap/UFRN), dialoguing with author(s) such as Marina Marcondes Machado (2010a; 2010b; 2015). It develops intersections between performance and childhoods, articulating an afro-playful methodology with the children’s protagonism. The artistic, afro-referenced and performative narratives of the authors raise contemporary considerations, providing findings for this discussion.

The Playing of the Child Performer with Orixás: artistic and afro-referenced experimentations – This article presents excerpts from a master’s dissertation in Performing Arts about performances of children’s playing bodies, in Early Childhood Education, based on the Orixás universe. It initially reveals the participating children (NEI/Cap/UFRN), dialoguing with author(s) such as Marina Marcondes Machado (2010a; 2010b; 2015). It develops intersections between performance and childhoods, articulating an afro-playful methodology with the children’s protagonism. The artistic, afro-referenced and performative narratives of the authors raise contemporary considerations, providing findings for this discussion.

This article presents excerpts from a master’s dissertation in Performing Arts about performances of children’s playing bodies, in Early Childhood Education, based on the Orixás universe. It initially reveals the participating children (NEI/Cap/UFRN), dialoguing with author(s) such as Marina Marcondes Machado (2010a; 2010b; 2015). It develops intersections between performance and childhoods, articulating an afro-playful methodology with the children’s protagonism. The artistic, afro-referenced and performative narratives of the authors raise contemporary considerations, providing findings for this discussion.

Este artigo apresenta recortes de uma dissertação de mestrado em Artes Cênicas sobre performances dos corpos brincantes de crianças, na Educação Infantil, a partir do universo de orixás. Revela inicialmente as crianças participantes (NEI/Cap/UFRN), dialogando com autoras(es) como Marina Marcondes Machado (2010a; 2010b; 2015). Desenvolvem-se cruzamentos entre performance e infâncias, articulando uma metodologia afrobrincante com os protagonismos das crianças. Suas narrativas artísticas, afrorreferenciadas e performáticas suscitam reflexões contemporâneas, constituindo achados para esta discussão.

 Este artigo apresenta recortes de uma dissertação de mestrado em Artes Cênicas sobre performances dos corpos brincantes de crianças, na Educação Infantil, a partir do universo de orixás. Revela inicialmente as crianças participantes (NEI/Cap/UFRN), dialogando com autoras(es) como Marina Marcondes Machado (2010a; 2010b; 2015). Desenvolvem-se cruzamentos entre performance e infâncias, articulando uma metodologia afrobrincante com os protagonismos das crianças. Suas narrativas artísticas, afrorreferenciadas e performáticas suscitam reflexões contemporâneas, constituindo achados para esta discussão.

Climate change and rapid population ageing pose challenges for communities and public policies. This systematic review aims to gather data from studies that present health indicators establishing the connection between climate change and the physical and mental health of the older population (≥ 65 years), who experience a heightened vulnerability to the impacts of climate change when compared to other age cohorts. This review was conducted according to the PICO strategy and following Cochrane and PRISMA guidelines. Three databases (PubMed, Scopus and Greenfile) were searched for articles from 2015 to 2022. After applying inclusion and exclusion criteria,nineteen studies were included. The findings indicated that various climate change phenomena are associated with an elevated risk of mortality and morbidity outcomes in older adults. These included cardiovascular, respiratory, renal, and mental diseases, along with physical injuries. Notably, the impact of climate change was influenced by gender, socioeconomic status, education level, and age—vulnerability factors. Climate change directly affected the health of older adults through ambient temperature variability, extreme and abnormal temperatures, strong winds, sea temperature variability, extreme El Niño-southern Oscillation (ENSO) conditions and droughts, and indirectly by air pollution resulting from wildfires. This review presents further evidence confirming that climate change significantly impacts the health and well-being of older adults. It highlights the urgency for implementing effective strategies to facilitate adaptation and mitigation, enhancing the overall quality of life for all individuals.

In 2022-23, the world witnessed the largest recorded outbreak of monkeypox virus (MPXV). Neurological manifestations were reported alongside the detection of MPXV DNA and MPXV-specific antibodies in the cerebrospinal fluid of patients. Here, we analyze the susceptibility of neural tissue to MPXV using human neural organoids (hNOs) exposed to a clade IIb isolate. We report susceptibility of several cell types to the virus, including neural progenitor cells and neurons. The virus efficiently replicates in hNOs, as indicated by the exponential increase of infectious viral titers and establishment of viral factories. Our findings reveal focal enrichment of viral antigen alongside accumulation of cell-associated infectious virus, suggesting viral cell-to-cell spread. Using an mNeonGreen-expressing recombinant MPXV, we confirm cell-associated virus transmission. We furthermore show the formation of beads in infected neurites, a phenomenon associated with neurodegenerative disorders. Bead appearance precedes neurite-initiated cell death, as confirmed through live-cell imaging. Accordingly, hNO-transcriptome analysis reveals alterations in cellular homeostasis and upregulation of neurodegeneration-associated transcripts, despite scarcity of inflammatory and antiviral responses. Notably, tecovirimat treatment of MPXV-infected hNOs significantly reduces infectious virus loads. Our findings suggest that viral disruption of neuritic transport drives neuronal degeneration, potentially contributing to MPXV neuropathology and revealing targets for therapeutic intervention. The mechanisms underlying neurological complications of monkeypox virus infection remain unclear. Here, the authors investigate its neurotropic potential and show that neuritic transport of viral particles drives neuronal degeneration.

In the absence of viremia, the diagnostics of Zika virus (ZIKV) infections must rely on serological techniques. In order to improve the serological diagnosis of ZIKV, ZIKV-IgA and ZIKV-IgG avidity assays were evaluated. Forty patients returning from ZIKV endemic areas, with confirmed or suspected ZIKV infections were studied. Samples were classified as early acute, acute and late acute according to the number of days post illness onset. Low avidity IgG was only detected at acute and late acute stages and IgA mostly at the early acute and acute stages. The date of sampling provides useful information and can help to choose the best technique to use at a determined moment in time and to interpret low avidity IgG and IgA results, improving the serological diagnosis of ZIKV.