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The Economic and ethical rationality is a joint of the efficiency imperative and freedom when it is a question of acting \"economically\". It is about an evolution the economic rationality concept through the various coordination modes (the market, the hierarchy, the agreements, the standards (including the Ethical values) and rules). The Ethical dimension the basis of motivation joins in the rationality postulate evolution process giving rise to the new solidarity economy appearance a first stage of a progress leading towards a sustainable development.

This research aimed to characterize the key components of the essential oil extracted from Salvia rosmarinus Spenn. (formerly Rosmarinus officinalis L.) through hydrodistillation and to explore its in vivo wound healing, antinociceptive, and antibacterial properties. Notable compounds identified in the essential oil included d-camphor, camphene, α-pinene, and eucalyptol. In vivo experiments involved inducing wounds in mice, which were then treated with the essential oil, leading to significantly accelerated wound healing and repair with a topical application success rate of 82.6%. The analgesic activity of the essential oil was evaluated by the acetic acid test in mice: the results indicated that a dose of 400 mg/kg led to 96.24% pain inhibition. The antibacterial properties of S. rosmarinus were evaluated using the agar diffusion method, demonstrating strong antibacterial activity against both Staphylococcus aureus and Escherichia coli, with inhibition zone diameters of 17 mm and 15 mm, respectively. To support the phytochemical analysis, in silico studies were made to identify potential compounds from 30 S. rosmarinus essential oils that could inhibit significant drug targets such as human cyclooxygenase-2 (hCOX-2), an anti-inflammatory target, and human transient receptor potential vanilloid1 (hTRPV1), a highly sought-after pain therapy target. These identifications were conducted using molecular docking and molecular dynamics simulation methods. Overall, this study supports the therapeutic use of S. rosmarinus for pain prevention and wound healing, underscoring its potential for developing clinically valuable products.

Hypertrophic cardiomyopathy (HCM) with midventricular obstruction (MVO) is a rare condition occurring in 1% of HCM patients. It is characterized by asymmetric left ventricular hypertrophy with MVO and elevated intraventricular pressure gradients. Pulmonary embolism has been associated with mid-ventricular obstructive HCM. Briefly, this case presents an unusual clinical scenario where a young pregnant woman suffering from hypertrophic obstructive cardiomyopathy presents with dyspnea hemodynamic compromise related to pulmonary embolism illustrating hemodynamic challenges created by pregnancy and surgery. We concluded that simple measures such as communication between the cardiology and obstetric teams, understanding of the hemodynamic changes, anesthetic planning, and monitoring were paramount for the success in our patient.