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Electroencephalography (EEG) remains an essential method for monitoring brain activity, but the limitations of conventional systems due to the complexity of installation and lack of portability have led to the introduction and development of in-ear EEG technology. In-ear EEG is an emerging method of recording electrical activity in the brain and is an innovative concept that offers multiple advantages both from the point of view of the device itself, which is easily portable, and from the user’s point of view, who is more comfortable with it, even in long-term use. One of the fundamental components of this type of device is the electrodes used to capture the EEG signal. This innovative method allows bioelectrical signals to be captured through electrodes integrated into an earpiece, offering significant advantages in terms of comfort, portability, and accessibility. Recent studies have demonstrated that in-ear EEG can record signals qualitatively comparable to scalp EEG, with an optimized signal-to-noise ratio and improved electrode stability. Furthermore, this review provides a comparative synthesis of performance parameters such as signal-to-noise ratio (SNR), common-mode rejection ratio (CMRR), signal amplitude, and comfort, highlighting the strengths and limitations of in-ear EEG systems relative to conventional scalp EEG. This study also introduces a visual model outlining the stages of technological development for in-ear EEG, from initial research to clinical and commercial deployment. Particular attention is given to current innovations in electrode materials and design strategies aimed at balancing biocompatibility, signal fidelity, and anatomical adaptability. This article analyzes the evolution of EEG in the ear, briefly presents the comparative aspects of EEG—EEG in the ear from the perspective of the electrodes used, highlighting the advantages and challenges of using this new technology. It also discusses aspects related to the electrodes used in EEG in the ear: types of electrodes used in EEG in the ear, improvement of contact impedance, and adaptability to the anatomical variability of the ear canal. A comparative analysis of electrode performance in terms of signal quality, long-term stability, and compatibility with use in daily life was also performed. The integration of intra-auricular EEG in wearable devices opens new perspectives for clinical applications, including sleep monitoring, epilepsy diagnosis, and brain–computer interfaces. This study highlights the challenges and prospects in the development of in-ear EEG electrodes, with a focus on integration into wearable devices and the use of biocompatible materials to improve durability and enhance user comfort. Despite its considerable potential, the widespread deployment of in-ear EEG faces challenges such as anatomical variability of the ear canal, optimization of ergonomics, and reduction in motion artifacts. Future research aims to improve device design for long-term monitoring, integrate advanced signal processing algorithms, and explore applications in neurorehabilitation and early diagnosis of neurodegenerative diseases.

Small soluble species of amyloid-beta (Aβ) formed during early peptide aggregation stages are responsible for several neurotoxic mechanisms relevant to the pathology of Alzheimer’s disease (AD), although their interaction with the neuronal membrane is not completely understood. This study quantifies the changes in the neuronal membrane elasticity induced by treatment with the two most common Aβ isoforms found in AD brains: Aβ40 and Aβ42. Using quantitative atomic force microscopy (AFM), we measured for the first time the static elastic modulus of living primary hippocampal neurons treated with pre-aggregated Aβ40 and Aβ42 soluble species. Our AFM results demonstrate changes in the elasticity of young, mature and aged neurons treated for a short time with the two Aβ species pre-aggregated for 2 hours. Neurons aging under stress conditions, showing aging hallmarks, are the most susceptible to amyloid binding and show the largest decrease in membrane stiffness upon Aβ treatment. Membrane stiffness defines the way in which cells respond to mechanical forces in their environment and has been shown to be important for processes such as gene expression, ion-channel gating and neurotransmitter vesicle transport. Thus, one can expect that changes in neuronal membrane elasticity might directly induce functional changes related to neurodegeneration.

Background and Objective: Infectious diseases continue to be a global burden and their impact is even worse if the patients already have other comorbidities. Because chronic kidney disease is very frequent, affecting 10% of the population, our study aims to explore the impact that infectious events have on its progression. Material and Methods: This is a retrospective, observational study based on a cohort of 238 dialyzed patients from the Nephrology Clinic of “Dr. Carol Davila” Clinical Hospital of Nephrology, Bucharest, who were followed from their first visit for five years, between 1 January 2007 and 1 January 2022. For each of them, the presence of an infectious event and the moment of the initiation of dialysis were recorded. Results: Statistical analysis showed that the patients who had at least one infectious episode were older (p = 0.004), their hemoglobin and lymphocytes were significantly lower (p = 0.03 and p = 0.02, respectively) and the time until the initiation of dialysis was lower (p = 0.007). Also, the preservation of kidney function was influenced by the number and the severity of infectious episodes. In the univariate Cox model, the following variables were associated with increased risk of dialysis: advanced age (p: 0.009; HR: 1.021; CI: 1.005 to 1.036), low hemoglobin (p: 0.001; HR: 0.861; CI: 0.786 to 0.943), previous diagnosis of chronic obstructive pulmonary disease (p: 0.002; HR: 2.467; CI: 1.376 to 4.424), presence of hematuria (p: 0.03; HR: 1.604; CI: 1.047 to 2.457) and increased values of proteinuria (p: 0.01; HR: 1.122; CI: 1.028 to 1.224) and of serum creatinine measured both at the time of the first visit and at the time of each infectious event (p: <0.001; HR: 1.262; CI: 1.141 to 1.396). Also, the presence of an infectious episode was associated with a 1.7-fold increase in the risk of dialysis initiation. The independent predictors of survival identified by the multivariate Cox model were age (p: 0.004; HR: 1.034; CI: 1.010–1.058), serum creatinine (p: <0.001; HR: 1.421; CI: 1.203 to 1.658) and proteinuria (p: <0.001; HR: 1.241; CI: 1.126 to 1.369) at the time of enrollment, but also the presence of an infectious episode during the patient’s evolution (p: 0.04; HR: 1.705; CI: 1.013 to 2.868). Conclusions: In the evolution of patients with chronic kidney disease, an active search for individual factors favoring the occurrence of infectious episodes should be taken into consideration to prevent a faster progression toward end-stage kidney disease.

Rural tourism and agritourism are essential drivers of sustainable economic development in mountain regions, generating income opportunities while preserving cultural and natural heritage. The North-West region of Romania has significant potential in this sector. Yet, tourism development is unevenly distributed, and the integration of local economic activities remains limited, an imbalance that reduces the overall impact of tourism on regional sustainability and economic resilience. To assess viable strategies for agritourism development, the study applies the TOPSIS method, evaluating four key criteria: infrastructure accessibility, diversity of tourism experiences, service quality, and long-term economic sustainability. A survey was conducted with 102 respondents, and the collected data were analyzed using the TOPSIS framework to determine the most effective development approaches. The findings indicated that the ecotourism trails represent the most favorable strategy (Ci = 0.678), followed by promoting local products within tourism (Ci = 0.602) and expanding rural guesthouses (Ci = 0.467). In contrast, integrated tourism packages and tourist information centers ranked lower, suggesting that infrastructure investment and the strategic use of local resources should be prioritized. These insights provide practical recommendations for policymakers, investors, and local stakeholders, emphasizing the need for targeted support in ecotourism and rural economic initiatives. Furthermore, the study contributes to academic research by offering a structured, replicable approach to evaluating rural tourism development. By highlighting sustainable investment directions, the findings support efforts to enhance Romania’s rural tourism competitiveness while fostering economic growth in mountain regions.

Romania faces a double challenge in the swine production sector. On one hand, the European Union’s environmental agenda demands that member states drastically reduce both the carbon footprint and the use of antibiotics in animal husbandry by 2030. On the other hand, the Romanian swine industry still grapples with long-standing internal issues such as excessive fragmentation, a strong dependence on imported piglets and feed materials, and a clear shortage of modern management experience. This study set out to explore how the ADKAR model can serve as a structured approach to help commercial swine farms in Romania transition toward sustainability. To gather relevant data, researchers distributed a five-point Likert-scale questionnaire to 83 farm managers, out of the 361 officially registered commercial swine farms. The instrument was designed to assess how each farm positioned itself across the five ADKAR dimensions. The results revealed that most Romanian farm managers are highly aware of the need for change and show a generally positive attitude toward adopting sustainable practices. However, there remain considerable knowledge gaps and practical limitations, which continue to act as major barriers to effective implementation. The composite ADKAR-S Index, which measures the “sustainability maturity” of each farm, displayed a strong positive correlation with economic performance, particularly the profit margin (r ≈ 0.45, p < 0.001), and a significant negative correlation with antimicrobial use (r ≈ −0.50, p < 0.001). Simply put, farms that are better prepared for organizational transformation tend to perform better financially while also reducing their environmental footprint. The findings suggest that policy efforts should prioritize human capital development, especially through training programs and reinforcement systems such as continuous monitoring and staff incentives, to ensure that sustainable practices are not only adopted but also maintained in the long run.

Daylighting design is not only dimensioning glazed surfaces to provide sufficient natural light to an occupied space but also a method of analyzing how this can be achieved without unwanted effects, such as gains and losses of heat, glare, and variations in daylighting intensity at various indoor distances and levels. The case study presented in this paper highlights the energy consumed due to a group of windows with a large glazed area in an existing building located in a temperate continental climate area. The energy consumption results from supplementary artificial lighting required to maintain adequate illumination for indoor activities and to counterbalance heat loss during colder periods are evaluated. The analysis performed by modifying the glazed surface led to the identification of an optimum value of window dimensions for minimum energy consumption. The results of the case study highlight the fact that the evolution of the total energy consumption, evaluated as the sum of the energy consumption due to additional heating/cooling and the artificial lighting required to compensate for the reduction in natural light, is strongly influenced by the dimensions of the glazed surfaces, as well as the minimum level of lighting imposed by the regime of activities carried out in the building. Thus, the outcomes obtained in the research show that at lighting values below 500 lx, the total energy consumption is directly proportional to the glazed surface. From values of 500 lx for the illuminance level, the total energy consumption drops from 2730 kWh/year for a window height of 230 cm to 2399 kWh/year for a height of 110 cm, after which it starts to rise again, reaching a value of 2786 kWh/year for a height of 30 cm. This phenomenon is also found at values higher than 500 lx; accordingly, for an imposed lighting of 1000 lx, the minimum total consumption is identified at a window height of 150 cm. The case study presented in this paper clearly highlights a complex relationship between the height of the glazed surface and the energy consumption required to compensate for heating or cooling and the reduction in natural lighting. Lower window heights reduce heat loss or gain but also correspondingly increase the energy consumption of artificial lighting.

Agritourism is increasingly recognized as a driver of sustainable rural development, yet research has often focused on ecological and economic outcomes while neglecting the human capital that sustains service quality. This study introduces the concept of human sustainability capital and links it with the ESG (Environmental, Social, Governance) framework and emotional labor theory, using case studies from Maramureș and Bucovina, Romania. Data were collected in summer 2025 through two surveys: one of 120 tourists assessing satisfaction, challenges, and improvement needs, and one of 45 agritourism hosts and employees examining emotional labor, job satisfaction, and ESG-related practices. Tourists reported high satisfaction with hospitality, food, landscapes, and cultural authenticity but noted shortcomings in infrastructure, activity variety, and crowding during peak seasons. Hosts and employees showed strong motivation and cultural pride, with genuine engagement more frequent than surface acting, yet many reported fatigue, low pay, and limited access to training. Social and cultural benefits were evident, environmental practices were modest, and governance emerged as the weakest pillar. Strengthening governance through professional development, fair labor conditions, and infrastructural support is crucial to maintain authenticity, protect cultural heritage, and ensure the long-term resilience of agritourism.

While accelerating globalization and technological transformation, traditional food products occupy a vulnerable yet strategically important position, straddling the line between cultural preservation and the need to remain economically viable. This study assesses both the sustainability and economic potential of traditional food items specific to Bihor County, Romania, with particular attention to their integration into contemporary value chains. A mixed-methods design was employed, combining structured surveys with 137 local consumers and semi-structured interviews with 20 regional producers. This research focused on consumer awareness, purchasing behavior, and producers’ readiness to engage with digital tools, within the broader framework of human-centered development and the Industry 5.0 paradigm. Findings reveal a modest but consistent link between familiarity and the willingness to pay a premium, although the frequency of consumption appeared to be unaffected. Sustainability emerged as a widely held value, commonly associated with seasonality, natural ingredients, and artisanal methods. On the supply side, producers showed a cautious openness to digital adoption, often tempered by a strong desire to preserve traditional practices. Based on these insights, this study outlines a territorially grounded framework for enhancing the resilience of traditional foods. Policy recommendations include support for user-friendly digital platforms, improved rural infrastructure, and initiatives that reinforce the regional gastronomic identity.

This study applied the Analytic Hierarchy Process (AHP) to determine the priority criteria for sustainable tourism development in Peștera Village, focusing on six essential areas: Environmental Sustainability, Economic Benefits, Cultural and Social Preservation, Infrastructure and Accessibility, Tourism Experience and Satisfaction, and Policy and Regulation Compliance. The AHP analysis demonstrated that Environmental Sustainability emerged as the top priority, emphasizing the need for tourism practices that preserve the village’s natural environment and ecosystems. Economic Benefits closely followed, highlighting the community’s recognition of tourism as a crucial driver for local economic growth, job creation, and income generation. The combination of these two criteria indicates a clear alignment between ecological preservation and the village’s economic aspirations, which are both fundamental to achieving long-term sustainable development. This research contributes to an improved understanding of sustainable practices in mountain tourism, offering insights applicable to similar tourism regions. By aligning environmental, economic, and cultural priorities, this study supports the development of comprehensive policies aimed at fostering resilience and sustainability in mountain tourism destinations worldwide.

Baroclinic instability is a fundamental mechanism of midlatitude atmospheric variability, and the Eady model remains one of its most useful idealized representations. In this work, we revisit the Eady configuration from the viewpoint of solution-space geometry rather than the classical normal-mode/growth-rate analysis. Starting from the reduced Eady vertical-structure equation, we show that the ratio of two independent solutions satisfies a Schwarzian-type relation that is invariant under homographic transformations, which naturally leads to an SL(2R) projective symmetry of the solution family. On this basis, we introduce a complex amplitude representation and reformulate coherence in terms of phase–amplitude synchronization constrained by projective invariants. Using Riccati-type constructions along geodesic parametrizations, the reduced dynamics are connected to a Stoler-type transform. Numerical exploration of the reduced model shows a systematic dependence on the control parameter ω: small ω is associated with simple oscillatory or burst-like behavior, intermediate ω with period-doubling-like behavior, and large ω with strongly modulated dynamics and more intricate reconstructed attractors. These results should be interpreted as properties of the reduced symmetry-based model, and they suggest that projective invariants may provide a useful framework for classifying organization regimes in Eady-type disturbances, complementary to classical growth-rate analyses.