Explore the vast range of titles available.

Background Laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC) with thyroid cartilage invasion are considered T4 and need total laryngectomy. However, the accuracy of preoperative diagnosis of thyroid cartilage invasion remains lower. Therefore, the purpose of this study was to assess the potential of computed tomography (CT)-based radiomics features in the prediction of thyroid cartilage invasion from LHSCC. Methods A total of 265 patients with pathologically proven LHSCC were enrolled in this retrospective study (86 with thyroid cartilage invasion and 179 without invasion). Two head and neck radiologists evaluated the thyroid cartilage invasion on CT images. Radiomics features were extracted from venous phase contrast-enhanced CT images. The least absolute shrinkage and selection operator (LASSO) and logistic regression (LR) method were used for dimension reduction and model construction. In addition, the support vector machine-based synthetic minority oversampling (SVMSMOTE) algorithm was adopted to balance the dataset and a new LR-SVMSMOTE model was constructed. The performance of the radiologist and the two models were evaluated with receiver operating characteristic (ROC) curves and compared using the DeLong test. Results The areas under the ROC curves (AUCs) in the prediction of thyroid cartilage invasion from LHSCC for the LR-SVMSMOTE model, LR model, and radiologist were 0.905 [95% confidence interval (CI): 0.863 to 0.937)], 0.876 (95%CI: 0.830 to 0.913), and 0.721 (95%CI: 0.663–0.774), respectively. The AUCs of both models were higher than that of the radiologist assessment (all P  < 0.001). There was no significant difference in predictive performance between the LR-SVMSMOTE and LR models ( P  = 0.05). Conclusions Models based on CT radiomic features can improve the accuracy of predicting thyroid cartilage invasion from LHSCC and provide a new potentially noninvasive method for preoperative prediction of thyroid cartilage invasion from LHSCC.

The EHT collaboration released in 2019 the first horizon-scale images of a black hole accretion flow, opening a novel route for plasma physics comprehension and gravitational tests. Although the present unresolved images deeply depend on the astrophysical properties of the accreted matter, GR predicts that they contain highly lensed observables, the \"photon rings\", embodying the effects of strong-field gravity. Focusing on the supermassive black hole M87* and adopting a geometrically thin, equatorial disc as a phenomenological configuration for the accreting matter, our goal is to study the degeneracy of spacetime curvature and of physically-motivated emission processes on EHT-like images observed at 230 and 345 GHz. In a parametric framework, we simulate adaptively ray-traced images using GYOTO in various spherically-symmetric spacetime geometries, for a comprehensive class of disc velocities and realistic synchrotron emission profiles. We then extract the width and the peak position of 1D intensity cross sections on the direct image and the first photon ring. We show that, among the investigated quantities, the most appropriate observables to probe the geometry are the peak positions of the first photon ring. Small geometric deviations can be unequivocally detected, regardless of the motion of the disc, ranging from a Keplerian to a radially infalling one, if the black hole mass-to-distance estimate is accurate up to around 2%; the current uncertainty of 11% being sufficient just to access extreme deviations. The equatorial set-up of this paper, favoured by present EHT observations of M87*, is adapted to model future measurements at higher observing frequencies, where absorption effects are negligible, and with higher resolution, indispensable to resolve the photon rings. Additional work is needed to investigate if our conclusions hold for more realistic disc configurations.

We present that the broad feature usually observed in X-ray spectra can be explained by a ray-traced emission from a two-slab system containing a dissipative, warm corona on top of an accretion disk in an AGN. Such an accretion flow is externally illuminated by X-ray radiation from a lamp located above a central SMBH. Thermal lines from highly ionized iron ions (FeXXV and FeXXVI), caused by both internal heating and reflection from the warm corona, can be integrated into an observed broad line profile due to the close vicinity of the SMBH. We investigate the dependence of the broad line profile by varying the SMBH spin parameter, viewing angle, lamp height, and dissipation factor. Our results introduce a new method to probe properties of the warm corona using high-resolution spectroscopic measurements. We use the photoionization code TITAN to compute local ion populations and emission line profiles, and the ray-tracing code GYOTO to include relativistic effects on the outgoing X-ray spectrum. In our models, the temperature of the inner atmosphere covering the disk can reach values of 10^7 - 10^8 K due to internal warm corona dissipation and external illumination, which is adequate for generating the highly ionized iron lines. These lines can undergo significant gravitational redshift near the black hole, leading to a prominent spectral feature centered around 6.4 keV. For all computed models, the relativistic corrections shift highly ionized iron lines to the X-ray region, usually attributed to fluorescent emission from the illuminated skin of an accretion disk. Hence, in the case of a warm corona covering the inner disk regions, the resulting theoretical line profile under strong gravity is a sum of different iron line transitions, and those originating from highly ionized iron contribute the most to the observed total line profile in AGN.

Sagittarius A*, the supermassive black hole at the center of our galaxy, exhibits episodic near-infrared flares. The recent monitoring of three such events by the GRAVITY instrument has shown that some flares are associated with orbital motions in the close environment of the black hole with super Keplerian velocity. We develop a semi-analytic model of Sagittarius~A* flares based on an ejected large plasmoid, inspired by recent particle-in-cell global simulations of black hole magnetospheres. We model the infrared astrometric and photometric signatures associated to this model. We consider a spherical large plasmoid ejected along a conical orbit around the black hole. This plasmoid is assumed to be formed by successive mergers of smaller plasmoids produced through magnetic reconnection. Non-thermal electrons are injected in the plasmoid. We compute the evolution of the electron-distribution under the influence of synchrotron cooling. We solve the radiative transfer problem and transport the radiation along null geodesics of the Schwarzschild spacetime. We also take into account the quiescent radiation of the accretion flow, on top of which the flare evolves. For the first time, we successfully account for the astrometric and flux variations of the GRAVITY data with a flare model that incorporates an explicit modeling of the emission mechanism. We find good agreement between the prediction of our model and the recent data. In particular, the azimuthal velocity is set by the magnetic field line it belongs to, which is anchored in the inner parts of the accretion flow, hence the super-Keplerian motion. The astrometric track is also shifted with respect to the center of mass due to the quiescent radiation, in agreement with the difference measured with the GRAVITY data. These results support the picture of magnetic reconnection as a viable model for Sagittarius~A* infrared flares.

The supermassive black hole Sagittarius A* (Sgr A*) is located at the dynamical center of the Milky Way. In a recent study of the X-ray flaring activity from Sgr A* using Chandra, XMM-Newton and Swift data from 1999 to 2015, it has been argued that the bright flaring rate has increased from 2014 Aug. 31 while the faint flaring rate decreased from around 2013 Aug. We tested the persistence of these changes in the flaring rates with new X-ray data of Sgr A* obtained in 2016-2018 (total exposure of 1.4Ms). We detected 9 flares in the Chandra data and 5 flares in the Swift data that we added to the set of 107 previously detected flares. We computed the intrinsic distribution of flare fluxes and durations corrected for the sensitivity bias using a new method that allowed us to take the error on the flare fluxes and durations into account. From this intrinsic distribution, we determined the average flare detection efficiency for each Chandra, XMM-Newton, and Swift observation. After correcting each observational exposure for this efficiency, we applied the Bayesian blocks algorithm on the concatenated flare arrival times. As in the above-mentioned study, we also searched for a flux and fluence threshold that might lead to a change in flaring rate. We improved the previous method by computing the average flare detection efficiencies for each flux and fluence range. The Bayesian block algorithm did not detect any significant change in flaring rate of the 121 flares. However, we detected an increase by a factor of about three in the flaring rate of the most luminous and most energetic flares that have occurred since 2014 Aug. 30. The X-ray activity of Sgr A* has increased for more than four years. Additional studies about the overall near-infrared and radio behavior of Sgr A* are required to draw strong results on the multiwavelength activity of the black hole.

Context. The Event Horizon Telescope (EHT) collaboration recently obtained first images of the surroundings of the supermassive compact object M87* at the center of the galaxy M87. Aims. We want to develop a simple analytic disk model for the accretion flow of M87*. Compared to general-relativistic magnetohydrodynamic (GRMHD) models, it has the advantage of being independent of the turbulent character of the flow, and controlled by only few easy-to-interpret, physically meaningful parameters. We want to use this model to predict the image of M87* assuming that it is either a Kerr black hole, or an alternative compact object. Methods. We compute the synchrotron emission from the disk model and propagate the resulting light rays to the far-away observer by means of relativistic ray tracing. Such computations are performed assuming different spacetimes (Kerr, Minkowski, non-rotating ultracompact star, rotating boson star or Lamy spinning wormhole). We perform numerical fits of these models to the EHT data. Results. We discuss the highly-lensed features of Kerr images and show that they are intrinsically linked to the accretion-flow properties, and not only to gravitation. This fact is illustrated by the notion of secondary ring that we introduce. Our model of spinning Kerr black hole predicts mass and orientation consistent with the EHT interpretation. The non-Kerr images result in similar quality of the numerical fits and may appear very similar to Kerr images, once blurred to the EHT resolution. This implies that a strong test of the Kerr spacetime may be out of reach with the current data. We notice that future developments of the EHT could alter this situation. Conclusions. Our results show the importance of studying alternatives to the Kerr spacetime in order to be able to test the Kerr paradigm unambiguously.

Context. Quasi-periodic oscillations (QPOs) are a common feature of the power spectrums of X-ray binaries. Currently it is not possible to unambiguously differentiate the large number of proposed models to explain these phenomena through existing observations. Aims. We investigate the observable predictions of a simple model that generates flux modulation: a spiral instability rotating in a thin accretion disk. This model is motivated by the accretion ejection instability (AEI) model for low- frequency QPOs (LFQPOs). We are particularly interested in the inclination dependence of the observables that are associated with this model. Methods. We develop a simple analytical model of an accretion disk, which features a spiral instability. The disk is assumed to emit blackbody radiation, which is ray-traced to a distant observer. We compute pulse profiles and power spectra as observed from infinity. Results. We show that the amplitude of the modulation associated with the spiral rotation is a strong function of inclination and frequency. The pulse profile is quasi-sinusoidal only at low inclination (face-on source). As a consequence, a higher-inclination geometry leads to a stronger and more diverse harmonic signature in the power spectrum. Conclusions. We present how the amplitude depends on the inclination when the flux modulation comes from a spiral in the disk. We also include new observables that could potentially differentiate between models, such as the pulse profile and the harmonic content of the power spectra of high-inclination sources that exhibit LFQPOs. These might be important observables to explore with existing and new instruments.

The goal of this paper is to investigate the detection by GRAVITY of different relativistic effects affecting the astrometric and/or spectroscopic observations of S2 such as the transverse Doppler shift, the gravitational redshift, the pericenter advance and higher-order general relativistic (GR) effects, in particular the Lense-Thirring effect due to the angular momentum of the black hole. We showed that the combination of S2 observations obtained with the GRAVITY instrument and the spectrograph SINFONI (Spectrograph for INtegral Field Observations in the Near Infrared) also installed at the VLT (Very Large Telescope) will lead to the detection of various relativistic effects. Such detections will be possible with S2 monitorings obtained within a few months or years, depending on the effect. Strong constraints on the angular momentum of Sgr~A* (e.g., at \\(1\\sigma~=~0.1\\)) with the S2 star will be possible with a simple stellar-orbit model without using a ray-tracing code but with approximating the gravitational lensing effect. However, long monitorings are necessary, and we thus must rely on the discovery of closer-in stars near Sgr~A* if we want to efficiently constrain the black hole parameters with stellar orbits in a short time, or monitor the flares if they orbit around the black hole.

The second-generation beam combiner at the Very Large Telescope (VLT), GRAVITY, observes the stars orbiting the compact object located at the center of our galaxy, with an unprecedented astrometric accuracy of 10 \\(\\mu\\)as. The nature of this compact source is still unknown since black holes are not the only candidates explaining the four million solar masses at the Galactic center. Boson stars are such an alternative model to black holes. This paper focuses on the study of trajectories of stars orbiting a boson star and a Kerr black hole. We put in light strong differences between orbits obtained in both metrics when considering stars with sufficiently close pericenters to the compact object, typically \\(\\lesssim 30~M\\). Discovery of closer stars to the Galactic center than the S2 star by the GRAVITY instrument would thus be a powerful tool to possibly constrain the nature of the central source.

We investigate the possibility to distinguish the small-coupling, slow-rotation black hole solution of Chern-Simons (CS) gravity from the Kerr solution. We develop simulations of electromagnetic observables in the vicinity of CS and Kerr black holes. We show that the typical relative observable difference between CS and Kerr spacetimes is of the order of 0.1% thus beyond reach of current or near-future instruments.