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"Wang, MingMing"
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Research on Audit Risk Prediction in Enterprise Management Based on Optimized BP Neural Network Algorithm
Under the development of enterprise management intelligence, there are more and more studies on the identification and evaluation of audit risks, in order to accurately identify enterprise audit risks, enterprises have created an audit risk identification model with artificial intelligence algorithm as the core, which aims to identify enterprise audit risks with high quality and significantly improve audit efficiency. After understanding the current research status of enterprise management audit risk prediction, this paper mainly discusses the risk assessment model of audit material misstatement based on the optimized B neural network algorithm based on the BP neural network algorithm and the basic concepts of enterprise audit work, and conducts verification and analysis based on practical cases, and finally proves that the prediction results of the model are effective and scientific, which is worthy of application in enterprise management.
Journal Article
Robust bilayer solid electrolyte interphase for Zn electrode with high utilization and efficiency
Construction of a solid electrolyte interphase (SEI) of zinc (Zn) electrode is an effective strategy to stabilize Zn electrode/electrolyte interface. However, single-layer SEIs of Zn electrodes undergo rupture and consequent failure during repeated Zn plating/stripping. Here, we propose the construction of a robust bilayer SEI that simultaneously achieves homogeneous Zn
2+
transport and durable mechanical stability for high Zn utilization rate (ZUR) and Coulombic efficiency (CE) of Zn electrode by adding 1,3-Dimethyl-2-imidazolidinone as a representative electrolyte additive. This bilayer SEI on Zn surface consists of a crystalline ZnCO
3
-rich outer layer and an amorphous ZnS-rich inner layer. The ordered outer layer improves the mechanical stability during cycling, and the amorphous inner layer homogenizes Zn
2+
transport for homogeneous, dense Zn deposition. As a result, the bilayer SEI enables reversible Zn plating/stripping for 4800 cycles with an average CE of 99.95% (± 0.06%). Meanwhile, Zn | |Zn symmetric cells show durable lifetime for over 550 h with a high ZUR of 98% under an areal capacity of 28.4 mAh cm
−2
. Furthermore, the Zn full cells based on the bilayer SEI functionalized Zn negative electrodes coupled with different positive electrodes all exhibit stable cycling performance under high ZUR.
The stabilization of the zinc electrode/electrolyte interface is critical for aqueous zinc battery operation. Here, authors report an electrolyte additive which promotes the formation of a bilayer solid electrolyte interphase, increasing the efficiency and utilization of zinc plating and stripping.
Journal Article
Global soil profiles indicate depth-dependent soil carbon losses under a warmer climate
Soil organic carbon (SOC) changes under future climate warming are difficult to quantify in situ. Here we apply an innovative approach combining space-for-time substitution with meta-analysis to SOC measurements in 113,013 soil profiles across the globe to estimate the effect of future climate warming on steady-state SOC stocks. We find that SOC stock will reduce by 6.0 ± 1.6% (mean±95% confidence interval), 4.8 ± 2.3% and 1.3 ± 4.0% at 0–0.3, 0.3–1 and 1–2 m soil depths, respectively, under 1 °C air warming, with additional 4.2%, 2.2% and 1.4% losses per every additional 1 °C warming, respectively. The largest proportional SOC losses occur in boreal forests. Existing SOC level is the predominant determinant of the spatial variability of SOC changes with higher percentage losses in SOC-rich soils. Our work demonstrates that warming induces more proportional SOC losses in topsoil than in subsoil, particularly from high-latitudinal SOC-rich systems.
The response of soil organic carbon to climate warming may be soil depth-dependent, but remains unquantified in situ. Here the authors show that warming induces more proportional soil carbon losses in topsoil than in subsoil, particularly from high-latitudinal carbon-rich soils.
Journal Article
Constructing robust heterostructured interface for anode-free zinc batteries with ultrahigh capacities
The development of Zn-free anodes to inhibit Zn dendrite formation and modulate high-capacity Zn batteries is highly applauded yet very challenging. Here, we design a robust two-dimensional antimony/antimony-zinc alloy heterostructured interface to regulate Zn plating. Benefiting from the stronger adsorption and homogeneous electric field distribution of the Sb/Sb
2
Zn
3
-heterostructured interface in Zn plating, the Zn anode enables an ultrahigh areal capacity of 200 mAh cm
−2
with an overpotential of 112 mV and a Coulombic efficiency of 98.5%. An anode-free Zn-Br
2
battery using the Sb/Sb
2
Zn
3
-heterostructured interface@Cu anode shows an attractive energy density of 274 Wh kg
−1
with a practical pouch cell energy density of 62 Wh kg
−1
. The scaled-up Zn-Br
2
battery in a capacity of 500 mAh exhibits over 400 stable cycles. Further, the Zn-Br
2
battery module in an energy of 9 Wh (6 V, 1.5 Ah) is integrated with a photovoltaic panel to demonstrate the practical renewable energy storage capabilities. Our superior anode-free Zn batteries enabled by the heterostructured interface enlighten an arena towards large-scale energy storage applications.
The development of dendrite-free, Zn-free anodes is challenging. Here, the authors design a two-dimensional antimony/antimony-zinc alloy heterostructured interface to achieve dendrite-free Zn deposition with areal capacity of 200 mAh cm
−2
, and energy density of around 270 Wh kg
−1
for anode-free zinc-bromine battery.
Journal Article
Research on liquidity risk of commercial bank – from the view of comparison of Chinese and American commercial banks
The liquidity risk of commercial banks has become an important driver of the major risks in the modern economic system. This paper synthesizes the off balance sheet items which are often ignored in traditional bank liquidity researches, and uses the method of tracking and comparative analysis in different window periods to explore the liquidity changes and possible risks of Chinese commercial banks before, during and after the financial crisis. It is found that traditional loan projects, committed loan projects and demand deposits are important drivers of liquidity risk; Although the liquidity level of China’s banks is high, due to the high demand deposit rate, low core capital ratio, rapid loan growth and high non-performing rate, and the lack of risk prevention awareness, liquidity risk is still a major risk that China’s commercial banks need to face.
Journal Article
Inheritance and reflection: “re-study” of three anthropology fieldwork sites in China’s Yunnan Province
This article is a research report involving three anthropological studies conducted during the period of “Kuige” and their “re-studies.” By narrating the project, I set forth my views on the connections and differences between Chinese anthropological explorations from two historical periods. These anthropological explorations refer to the study of Lu Village conducted by Fei Xiaotong, that of “West Town” (Xizhou) by Francis L. K. Hsu, and that of “Pai-IPai” (Dai) villages by Tien Ju-Kang. They were all completed in the late 1930s and early 1940s. Each writer extracted a framework to analyze the land system, ancestor worship, and the relationship between humans and gods from the writer’s own field experience. Despite the difference in research methods, all three studies noticed the cultural differences between rural society and modernity. Since 2000, Peking University and Yunnan Minzu University have launched a “Province-university Cooperation Project.” During the project, a research team formed of several young scholars revisited Lu Village, “West Town” (Xizhou), and Namu Village. These writers’ works were based on the data acquired in their fieldwork and drew upon the opinions raised by global anthropologists on “re-study” in recent decades. Considering the dual effects of social change and shifts in academic concepts around “follow-up research,” the scholars put forward several points of view with their ethnographies, which all featured the characteristics of inheritance and reflection. Based on the results of the three “re-studies,” this article emphasizes the importance of the study of public rituals for the research of rural society. This article also attempts to re-examine the methodology of “human ecology,” which profoundly impacts Chinese anthropology and sociology.
Journal Article
Polycystic Ovary Syndrome (PCOS): Symptoms, Causes, and Treatment
Objective: The review aims to provide an overview of the pathogenesis, clinical manifestations, and treatment methods of polycystic ovary syndrome (PCOS). Mechanism: The etiology of PCOS is multifaceted, intricately intertwined with genetic determinants, dysregulation of the hypothalamic-pituitary-ovarian axis, adrenal androgen excess, ethnic predilections, insulin resistance, persistent inflammatory cascades, lifestyle variables, non-coding RNA (ncRNA), and oxidative stress manifestations. Findings in Brief: Advances in PCOS research have led to updated diagnostic criteria that focus on irregular menstruation, along with the introduction of new treatments such as glucagon-like peptide-1 (GLP-1) agonists and sodium-glucose cotransporter 2 (SGLT2) inhibitors. Additionally, innovative reproductive technologies like in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) are showing promise in improving fertility outcomes for PCOS patients. Genetic and epigenetic studies are uncovering potential for personalized therapeutic interventions. Individuals with PCOS face increased risks of complications during pregnancy, such as pregnancy-induced hypertension and multiple gestation complications. Such advancements underscore the significance of precise diagnosis, personalized treatment approaches, and interdisciplinary collaboration in managing PCOS effectively. Conclusions: This review undertakes a comprehensive scrutiny of contemporary PCOS studies, illuminating its clinical manifestations, underlying pathophysiological mechanisms, and evolving treatment modalities. Advocating for a patient-centric, evidence-driven approach is imperative in mitigating the adversities associated with PCOS and fostering holistic well-being.
Journal Article
Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells
Pancreatic β cell dysfunction and reduction due to glucose toxicity play a crucial role in the development of type 2 diabetes mellitus (T2DM). Irisin, a novel exercise-induced myokine, reduces obesity, improves insulin resistance and lowers blood glucose by promoting the browning of white adipose tissue, thereby enhancing thermogenesis and increasing energy expenditure. Recent studies have reported that irisin promotes cell proliferation and protects cells from apoptosis. However, the effects of irisin on pancreatic β cells are unknown. Thus, the aim of this study was to investigate the effects and the potential underlying mechanisms of irisin on pancreatic β cell proliferation and apoptosis induced by high glucose. Both in vitro (INS-1 cells) and in vivo (a T2DM rat model) experiments were conducted. Irisin significantly increased the proliferation of INS-1 cells, with the most significant effect observed at 24 h with 100 ng/ml irisin. Irisin also promoted INS-1 cell proliferation via the ERK and p38 MAPK signaling pathways, protected the cells from high-glucose-induced apoptosis by regulating the expression of caspases, Bad, Bax, Bcl-2 and Bcl-xl, and improved pancreatic β cell function. Irisin significantly reduced the body weight and blood glucose values and increased the serum insulin levels of the diabetic rats. An oral glucose tolerance test (OGTT) indicated that irisin also improved the glucose tolerance of T2DM rats. Together, these findings suggest that irisin may have applications in the prevention and treatment of T2DM because of its protective effect on the secretion of pancreatic β cells.
Journal Article
Elevated CircYthdc2 expression is correlated with aggressive features and poor progression-free survival in hepatocellular carcinoma
Objective
Liver hepatocellular carcinoma (LIHC) is a major contributor to cancer-related mortality. While early detection is crucial for improving outcomes, current diagnostic methods lack optimal sensitivity and specificity. Circular RNAs (circRNAs) have emerged as promising biomarkers due to their stability and tissue-specific expression.
Methods
Bioinformatic analysis was performed using UALCAN database to examine YTHDC2 methylation and expression patterns. Tissue and serum samples were collected from 72 LIHC patients and matched controls. CircYTHDC2 expression was assessed in tissues, serum, and cell lines via qRT-PCR. CircYTHDC2’s diagnostic potential was evaluated through ROC analysis and stability testing. Associations between circYTHDC2 levels, clinicopathological features, and survival were analyzed.
Results
Bioinformatic analysis revealed reduced YTHDC2 promoter methylation and elevated expression in LIHC tissues. CircYTHDC2 showed significant upregulation in LIHC tissues, serum, and cell lines compared to controls. ROC analysis demonstrated high diagnostic accuracy for circYTHDC2 in tissues (AUC = 0.846) and serum (AUC = 0.788). CircYTHDC2 exhibited remarkable stability against RNase degradation. Elevated circYTHDC2 levels significantly correlated with advanced BCLC stage, larger tumor size, intrahepatic metastasis, and portal invasion. High circYTHDC2 expression was associated with shorter progression-free survival (
P
= 0.025). Additionally, we found circYTHDC2 bound to YTHDC2 and was positively regulated by YTHDC2 in an m6A-dependent manner.
Conclusion
CircYTHDC2 represents a stable, clinically viable biomarker for LIHC, demonstrating significant diagnostic accuracy and prognostic value. Its strong correlation with aggressive tumor features and survival outcomes suggests potential utility in clinical management of LIHC patients.
Journal Article