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3,086 result(s) for "Waqas, Muhammad"
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Simulation of revised nanofluid model in the stagnation region of cross fluid by expanding-contracting cylinder
Purpose This paper aims to address stagnation point flow of cross nanofluid in frames of hydromagnetics. Flow analysis subjected to expanding-contracting cylinder is studied. Design/methodology/approach Nonlinear problems are computed by using bvp4c procedure. Findings Radius of curvature and temperature-dependent heat sink-source significantly affects heat-mass transport mechanisms for cylindrical surface. Originality/value No such analysis has yet been reported.
A multiPMT for SWGO water Cherenkov detectors
Water Cherenkov detectors are playing a central role in neutrino physics, gamma-ray astronomy, and cosmic-ray research. These detectors usually rely on the use of large area photomultiplier tubes (PMTs) to detect Cherenkov radiation emitted by particles moving faster than the speed of light in water. Recent studies suggest that using multiple small area PMTs in a compact structure enhances the performance of these detectors. Such a solution has been adopted in several experiments. This work focuses on the design and optimization of a hemispherical module with several 3” PMTs, called multiPMT, and related electronics for possible use in the water Cherenkov detectors of the SWGO Experiment. This study shows that such devices have promising features in terms of both cost and performance compared to large-area PMTs. The cost per area of photocathode is similar to large PMTs even including the additional channels of electronics. Dividing the signal into multiple PMTs reduces requirements on the electronics max rate and max dynamic range. The enclosure which keeps the PMT face dry provides convenient housing for the electronics and allows for easy access in case of repair. Finally, the intrinsic directionality may prove useful for shower reconstruction and to the discrimination of gamma initiated showers against the hadron background.
How institutional quality, and energy production sources, affect the environmental sustainability of bri countries: A comparison of different income groups
Institutions and energy production sources shape environmental policies and practices. Institutions establish frameworks for renewable energy and enforce environmental protection measures. Conventional energy sources cause pollution and climate change, while green energy sources have lower environmental impacts. In this study we analyzed how quality institutions, along with different types of energy production sources affect the quality of environment in 101 countries that are part of the BRI, a global development project. We used a statistical method called panel quantile regression to analyze data from 2000 to 2020. We found that producing energy from renewable sources, such as wind and solar, reduces CO 2 emissions by 0.003% in BRI countries. However, producing energy from non-renewable sources, such as gas and coal, harms the environment more in high-income and middle-income countries. We also found that having better institutional quality reduces CO 2 emissions by 3.421%, 2.710%, and 0.006% in different groups of BRI countries. This means that having stronger and fairer institutions can help protect the environment by limiting the use of non-renewable energy sources and encouraging the use of renewable ones. Our study suggests that improving institutional quality is a key factor for achieving green energy and environmental sustainability in BRI countries.
Seed nano-priming with Zinc Oxide nanoparticles in rice mitigates drought and enhances agronomic profile
All cereal crops, particularly rice are perpetually affected due to drastic climatic changes which triggers different stressors resulting in food shortage scenarios across the globe. In modern era, application of nanotechnology holds the pledge in combating the climate change mediated environmental stressors through nanomaterials such as pesticides, nano-biosensors, nano-clays and nano-seed priming technologies. Current study is a part of experiment conducted to comprehend the behaviour of rice plants raised from Zinc Oxide nanoparticles (ZnONPs) primed seeds under the water shortage environment. The seed priming treatment concentrations included 0, 5, 10, 15, 25 and 50 ppm. In the experimental results an increase in plant height, total chlorophyll contents, plant fresh and dry weights was obtained by use of seed priming with ZnONPs. The study results proved that seed priming with 25ppm of ZnONPs increased seed and straw yield with value of 85.333 and 123.333, respectively under water deficit environment. The analysis depicted that 25 ppm has been found more suitable for increasing the 1000 paddy weight of rice plants under both well irrigated and water shortage conditions. Seed priming with ZnONPs results in 53% reduction in MDA contents of water stressed rice plants Drought stress leads to reduction in plant height by 31%, plant fresh weight by 22% and plant dry weight by 28%. Seed priming treatments imparted in current study show significance increase in plant biomass. Priming with ZnONPs further enhances the levels of proline amino acid facilitating the plant to combat water shortage stress. A further elevation in activities of SOD, CAT and POD takes place in rice plants raised from ZnONPs primed seeds by 11%, 13% and 38%, respectively. An elevation in activities of antioxidant enzymes was found and the levels of oxidative stress indicators decreased upon seed priming with ZnONPs. Furthermore the yield characteristics such as panicle length, number of tillers, paddy yield and straw yield of the rice plants raised through ZnONPs primed seeds enhanced. The ZnONPs at concentration of 25 ppm proved optimum in alleviating drought induced damages. It can be inferred that seed pre conditioning with ZnONPs is helpful in increasing yield attributes under the water shortage environment.
Linkages between environmental sustainability, disaggregated emission, renewable energy, and energy efficiency: An evidence from BRI countries
This paper examines the long-term and short-run causative relationship among environmental sustainability, energy efficiency, renewable energy and carbon emissions from all over sources (coal, oil and fossil fuels) and sector wise division (heat and power, transportation, residential, manufacturing and other sectors. The empirical evidence presented in this study is derived from a balanced panel dataset spanning the annual periods from 2000 to 2021. The dataset specifically focuses on a selection of BRI Countries. The Kao test demonstrates the presence of cointegration across variables such as carbon dioxide emissions, environmental suitability, energy efficiency and renewable energy. The Panel Pooled Mean Group-Autoregressive Distributed Lag (PMG-ARDL) model indicates a statistically significant positive association between the environmental sustainability and disaggregated CO 2 emissions over a long-term period. The study found a positive relationship between disaggregated CO 2 emissions and environmental sustainability and energy efficiency, with renewable energy sources reducing emissions. It suggests a need for a structural transition from an energy-intensive economy to a decarbonized one, with sectors like heat and power positively impacting sustainability. Implementing measures to reduce emissions is crucial for tackling climate change.
Nanocarriers-Mediated Drug Delivery Systems for Anticancer Agents: An Overview and Perspectives
Nanotechnology has been actively integrated as drug carriers over the last few years to treat various cancers. The main hurdle in the clinical management of cancer is the development of multidrug resistance against chemotherapeutic agents. To overcome the limitations of chemotherapy, the researchers have been developing technological advances for significant progress in the oncotherapy by enabling the delivery of chemotherapeutic agents at increased drug content levels to the targeted spots. Several nano-drug delivery systems designed for tumor-targeting are evaluated in preclinical and clinical trials and showed promising outcomes in cancerous tumors' clinical management. This review describes nanocarrier's importance in managing different types of cancers and emphasizing nanocarriers for drug delivery and cancer nanotherapeutics. It also highlights the recent advances in nanocarriers-based delivery systems, including polymeric nanocarriers, micelles, nanotubes, dendrimers, magnetic nanoparticles, solid lipid nanoparticles, and quantum dots (QDs). The nanocarrier-based composites are discussed in terms of their structure, characteristics, and therapeutic applications in oncology. To conclude, the challenges and future exploration opportunities of nanocarriers in chemotherapeutics are also presented.
BI-SENT: bilingual aspect-based sentiment analysis of COVID-19 Tweets in Urdu language
The COVID-19 pandemic resulted in over 600 million cases worldwide, and significantly impacted both physical and mental health, fostering widespread anxiety and fear. Consequently, the extensive use of online social networks to express emotions made sentiment analysis a crucial tool for understanding public sentiment. Traditionally, sentiment analysis in the Urdu language has focused on sentence-level analysis. However, aspect-level sentiment analysis is increasingly important and remains underexplored due to the challenges of the costly and time-consuming manual dataset annotation process. This study presents an innovative bilingual aspect-based sentiment analysis for Urdu and Roman Urdu using unsupervised methods. For Urdu, a syntactic rule-based approach achieves an accuracy of 83% in extracting aspect terms, marking a 5% improvement in F1-score over existing methods. For Roman Urdu, the study employs collocation patterns and topic modeling to identify and categorize key aspects, resulting in a perplexity score of –7 and a coherence score of 41. The results not only demonstrate the semantic coherence of the identified categories but also represent a significant advancement in aspect-level sentiment analysis by eliminating the need for manual annotation. This study offers new insights into the sentiments expressed during the pandemic, providing valuable feedback for policymakers and health organizations.
Non-markovian electron tunneling in SARS-CoV-2 virus infection in structured environments
The role of non-Markovian quantum effects in biological processes is increasingly recognized, yet remains largely unexplored in virology. This study investigates the influence of quantum tunneling on SARS-CoV-2 infection dynamics, focusing on the interaction between the viral spike protein and the host ACE2 receptor. We employed the non-Markovian quantum state diffusion (NMQSD) to model electron transfer mediated by vibrational modes within the structured lipid membrane. Our results challenge conventional semiclassical models by demonstrating that this interaction operates not in the weak coupling limit, but in an intermediate coupling regime where quantum coherence is pivotal. We find that specific vibrational modes significantly enhance tunneling efficiency and sustain coherence over extended timescales. Furthermore, our findings reveal a critical dependence on resonance: tunneling is highly efficient below resonance via resonance-assisted mechanisms, whereas tunneling rates decrease sharply above resonance due to decoherence effects. These results, which parallel coherence phenomena in photosynthesis, suggest that the host’s membrane environment actively optimizes electron transfer. This work presents a new paradigm for virus-host interactions and identifies the modulation of vibrational frequencies as a potential new avenue for antiviral drug design.
Green Innovation at the Crossroads of Financial Development, Resource Depletion, and Urbanization: Paving the Way to a Sustainable Future from the Perspective of an MM-QR Approach
Global warming has become a big problem around the world, and it is because of what people do. As a possible answer, countries are looking for ways to keep their economies growing and invest in technologies that use clean energy. Therefore, the notion of carbon neutrality has emerged as a crucial policy strategy for nations to attain sustainable development. This study expands the existing discussions on carbon neutrality by investigating the influence of key factors, including green innovation, financial development, natural resources depletion, trade openness, institutional quality, growth, and urbanization on the progress made towards attaining a carbon neutral state in the BRICS nations. This study considers the Method of Moment Quantile-Regression (MM-QR) and Prais–Winsten correlated panel corrected standard errors (PCSEs) estimators to investigate the study objectives over the period of 1990–2021. Under the investigated outcomes, this study validated the significant role of urbanization and growth in carbon neutrality. On the other hand, this study finds the positive role of openness, green innovation, resource depletion, institutional quality, and financial development on environmental deterioration. However, under a systematic analysis, this study utilizes different proxies of the financial sector, for instance, financial complexity, financial efficiency, financial stability, and domestic credit by financial sector, and provides interesting outcomes. Based on these outcomes, this study also provides suggestions to attain desired levels of sustainability.
Applying genomic resources to accelerate wheat biofortification
Wheat has low levels of the micronutrients iron and zinc in the grain, which contributes to 2 billion people suffering from micronutrient deficiency globally. While wheat flour is commonly fortified during processing, an attractive and more sustainable solution is biofortification, which could improve micronutrient content in the human diet, without the sustainability issues and costs associated with conventional fortification. Although many studies have used quantitative trait loci mapping and genome-wide association to identify genetic loci to improve micronutrient contents, recent developments in genomics offer an opportunity to accelerate marker discovery and use gene-focussed approaches to engineer improved micronutrient content in wheat. The recent publication of a high-quality wheat genome sequence, alongside gene expression atlases, variation datasets and sequenced mutant populations, provides a foundation to identify genetic loci and genes controlling micronutrient content in wheat. We discuss how novel genomic resources can identify candidate genes for biofortification, integrating knowledge from other cereal crops, and how these genes can be tested using gene editing, transgenic and TILLING approaches. Finally, we highlight key challenges remaining to develop wheat cultivars with high levels of iron and zinc.