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"Weaver, Helen"
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Occupational therapy for epidermolysis bullosa: clinical practice guidelines
The purpose of this article is to summarize the Dystrophic Epidermolysis Bullosa Research Association (DEBRA) International evidence-based Clinical Practice Guidelines (CPGs) for the provision of occupational therapy (OT) for children and adults living with inherited epidermolysis bullosa (EB). This is a rare genetic disorder characterized by skin fragility leading to blister formation occurring spontaneously or following minor trauma. Current OT practice for persons with EB is based on anecdotal care, clinical expertise and trial and error with collaboration between caregiver and patient. Intervention based on research is needed to establish a foundation of knowledge to guide international practitioners to create and improve standards of care and to be able to work effectively with those living with the rare diagnosis of this condition.
This CPG was created by an international panel with expertise working with persons with EB. The panel was made up of 11 members including OT’s, a physiotherapist, a medical doctor, social worker, person with EB and a carer of a person with EB. It describes the development of recommendations for 5 outcomes determined by survey of persons with EB, caregivers, and experienced healthcare professionals. The outcomes include independence in activities of daily living (ADL), independence in instrumental ADL, maximization of hand function (non-surgical), fine motor development and retention, and oral feeding skills. The recommendations are supplemented with additional files that include photos and specific examples to further guide occupational therapists or, in situations where an OT is not available, other members of the healthcare team.
As the disorder of EB is rare, evidence-based CPGs are needed to provide a base of knowledge and practice for OTs throughout the world with the goal of providing quality care to patients, while improving their functional independence and quality of life. In addition, this information is valuable as a basis for further research.
Journal Article
Laser pulmonary metastasectomy preserves parenchyma: a single-centre retrospective study from the United Kingdom
Pulmonary metastasectomy (PME) is a modality increasingly employed to control oligometastatic disease from a variety of solid tumours. All patients undergoing PME between September 2015 and August 2018 were included in our study. Those undergoing LAS were compared to a control of conventional stapled wedge metastasectomy (SWM). Data was analysed retrospectively from a prospective kept database. Statistical analysis was performed using JASP (Version 0.14.1). Fifty-seven procedures in 46 patients, were included in the final analysis. Demographic data was similar at baseline between the LAS and SWM group, with colorectal cancer being the most common primary, 44/57 (77%). LAS was favoured in patients who had previously undergone pulmonary metastasectomy, 9/12 (75%). Patients in the LAS group had a smaller parenchymal volume resected (MD 30.6 cm.sup.3, p = 0.0084), with a lower incidence of clear histological marginal resection (11/27 vs 29/30, p < 0.0001); but no difference in operative time, morbidity, patient-reported outcome measures, or local recurrence between the two groups at 2 years. LAS was associated with a lower procedural cost (MD £452.92, p < 0.0001). Laser-assisted pulmonary metastasectomy presents a safe and acceptable alternative to traditional stapled wedge resection, with notable parenchymal-sparing, no discernible learning curve, and lower direct costs.
Journal Article
Applications of the twisted Steenrod action to the hit problem
The polynomial algebra P = F2[t1,... ,tn] admits an action of the general linear group GL(n, F2) by matrix substitution and an action of the Steenrod Algebra A at the prime 2. The two actions commute, which implies that the algebra of invariants for any subgroup G C GL(n,F2) is an A-module. It is a fundamental problem to determine a minimal generating set for these modules PG for varying n and G. In this thesis we exploit an isomorphism of P with P = F2[x1,…,xn] described by Campbell and Selick in [3] in which the action of the Steenrod Algebra is a twisted one given by Sq1xi = x2i-1 .P is partitioned into 2n-1 vector subspaces by the action of a cyclic subgroup C2n-1of order 2n - 1. Each such subspace is an A-module under the twisted action of A. We determine generating sets for these A-modules for n = 2 and n = 3 and exploit the identification of M(0) with PG where G is the cyclic group C2n-1 to determine a generating set for the A-module PG. In order to establish linear independence of these generators we turn to the dual problem of finding the kernel, K, of the Steenrod action in the divided power algebra D. In particular, we define a twisted analogue, L, of a subring, L of K studied by Alghamdi Crabb and Hubbuck in [1]. Finally, we consider the A-module PG where G is a subgroup of order 21 in GL(3,F2).
Dissertation
STARTERS: Your letters: Tell us what you think
In response to Dr Hurst's 22 January letter, cancer obviously hits people who have to get up the morning after chemo, who are single parents or have other responsibilities...
Newspaper Article
Where has Martin been hiding this money?
Canada is the only Group of Eight nation without a national housing policy. From 1984 to 1993, the Brian Mulroney government cut $2 billion from the federal budget for housing and in 1993 all funding was eliminated. A 1990 Liberal government task force report by Paul Martin chastised the Conservative government for ignoring social housing. Noble words. But when Liberals took power in 1993, they continued to cut funding and downloaded responsibility for housing to the provinces in 1996.
Newspaper Article
MORE CURIOSITY, JOY, LESS FCAT
You bet it is! Look at the time and energy this state puts into dishing out the Florida Comprehensive Assessment Test. When an entire school system revolves around a single test -- the FCAT -- something isn't right. When the beginning of a school year hinges on getting the most time in to dwell on taking the FCAT, something isn't right! When Shakespeare or algebra are cut back to prepare more time for FCAT testing, something isn't right! Our children are being cheated!
Newspaper Article
FORMAN'S VISION FOR EDUCATION
In the South Florida Sun-Sentinel write-up of his life, it was mentioned that Dr. Forman felt education was something that could never be taken away from you. I heard that when growing up as well. Travel was the other item with my family. I am sure Dr. Forman agreed with that. I well recall when our children were passing through Nova Blanche Forman and had the opportunity to travel to Europe during Spring Break.
Newspaper Article