Explore the vast range of titles available.

\"This collection of essays by international specialists in the literature of Berlin provides a lively and stimulating account of writing in and about the city in the modern period. The first eight chapters chart key chronological developments from 1750 to the present day, while subsequent chapters focus on Berlin drama and poetry in the twentieth century and explore a set of key identity questions: ethnicity/migration, gender (writing by women), and sexuality (queer writing). Each chapter provides an informative overview along with closer readings of exemplary texts. The volume is designed to be accessible for readers seeking an introduction to the literature of Berlin, while also providing new perspectives for those already familiar with the topic. With a particular focus on the turbulent twentieth century, the account of Berlin's literary production is set against broader cultural and political developments in one of the most fascinating of global cities\"-- Provided by publisher.

\"These essays by leading figures from academia, architecture and the arts consider how cultures of memory are constructed for and in contemporary cities. They take Berlin as a key case of a historically burdened metropolis, but also extend to other global cities: Jerusalem, Buenos Aires, Cape Town and New York\"--Provided by publisher.

This article considers the possibility of taking Arthur Schnitzler, who is so constitutive of the cultural 'chronotope' of fin-de-siècle Vienna, as a paradigmatic figure of displacement. It is argued that his writings — in published and archival form — are populated by a set of fictional figures subject to dislocation and by figures of displacement in the sense of tropes or designs that reference that condition. Particular attention is given to the Ostjude [Eastern Jew] as a figure that displaces the framework of identity categories that operates in Schnitzler's texts. The article concludes with a small drawing from the author's archive and the analysis of a scene from Das weite Land [The Vast Domain, 1911] as allegorical representation of the condition of dislocation.

The effect of high salt concentration (100 mM NaCl) on the organization of photosystem I-light harvesting complex I supercomplexes (PSI-LHCI) of Chlamydomonas reinhardtii was studied. The electron transfer activity was reduced by 39% in isolated PSI-LHCI supercomplexes. The visible circular dichroism (CD) spectra associated with strongly coupled chlorophyll (Chl) dimers were reduced in intensity, indicating that pigment-pigment interactions were disrupted. This data is consistent with results from fluorescence streak camera spectroscopy, which suggest that red-shifted pigments in the PSI-LHCI antenna had been lost. Denaturing gel electrophoresis and immunoblot analysis reveals that levels of the PSI reaction center proteins PsaD, PsaE and PsaF were reduced due to salt stress. PsaE is almost completely absent under high salt conditions. It is known that the membrane-extrinsic subunits PsaD and E form the ferredoxin-docking site. Our results indicate that the PSI-LHCI supercomplex is damaged by reactive oxygen species at high salt concentration, with particular impact on the ferredoxin-docking site and the PSI-LHCI interface.

Abstract This article is concerned with the 2012 feature Lore, which was made in Germany by Australian director Cate Shortland and is based on the story of the same name by Rachel Seiffert. Focusing on a group of siblings and their odyssey across Germany at the end of World War II, the film explores questions of identity constitution and subversion in the transitional ground between childhood and adulthood, in particular as this is registered in bodily experience. The three main sections of this article focus on the family archive (not least through the medium of photography), structures of double identity (in particular around the figure of the German Jew), and aesthetic strategies of representation (especially framing and mirroring). Through these steps, the article probes the ethical, aesthetic, and political stakes involved in representing the passing of children through the violence of history in what the director calls “grey zones.”

Photosystem I has two branches of cofactors down which light-driven electron transfer (ET) could potentially proceed, each consisting of a pair of chlorophylls (Chls) and a phylloquinone (PhQ). Forward ET from PhQ to the next ET cofactor (FX) is described by two kinetic components with decay times of 20 and 200 ns, which have been proposed to represent ET from PhQB and PhQA, respectively. Immediately preceding each quinone is a Chl (ec3), which receives a H-bond from a nearby tyrosine. To decrease the reduction potential of each of these Chls, and thus modify the relative yield of ET within the targeted branch, this H-bond was removed by conversion of each Tyr to Phe in the green alga Chlamydomonas reinhardtii. Together, transient optical absorption spectroscopy performed in vivo and transient electron paramagnetic resonance data from thylakoid membranes showed that the mutations affect the relative amplitudes, but not the lifetimes, of the two kinetic components representing ET from PhQ to FX. The mutation near ec3A increases the fraction of the faster component at the expense of the slower component, with the opposite effect seen in the ec3B mutant. We interpret this result as a decrease in the relative use of the targeted branch. This finding suggests that in Photosystem I, unlike type II reaction centers, the relative efficiency of the two branches is extremely sensitive to the energetics of the embedded redox cofactors.

Introduction: Cardiovascular disease (CVD) accounted for almost 33% of global deaths in 2019 and remains a leading cause of acute emergency department (ED) attendance (1). Ischaemic heart disease represented more than 40% of these deaths, 80% of which are preventable (1) emphasizing the need for early identification, intervention, and education on risk factor prevention. This case study explores the effectiveness of a proactive cardiovascular screening service, incorporating AI-enabled technology and point of care (POC) blood testing, for timely and accurate predicting cardiovascular issues.  The methodology involved data collection through questionnaires, established screening protocols, digital tools with advanced AI algorithms, and adherence to ethical considerations. Case Study: An active 60 year old male, history of hypertension and pre-diabetes, no history of chest pain or palpitations, received a proactive cardiovascular risk assessment incorporating: POC HBA1C/NTproBNP (LumiraDX), a non-fasting lipid profile, Heartscience  MyoVista wavECG and cardiorespiratory auscultation. Findings: Elevated HBA1C, LDL and NON-HDL levels. Conventional ECG Glasgow Analysis suggested borderline prolonged QT and left ventricular hypertrophy. Positive MyoVista report for Left Ventricular (LV) repolarisation abnormality, indicative of diastolic dysfunction. Interventions: 24 hour blood pressure monitor revealed sub-optimal control: average 140/90mmHg with 4% nocturnal dipping. 3 day Holter monitor identified a supraventricular ectopic run at 149bpm, associated with a future risk of Atrial Fibrillation (afib). Lifestyle modification education provided. Advised the individual to attend his GP regarding blood pressure control and statin therapy, and referral to Cardiology for echo examination. Before the echo was planned, an episode of chest pain led to an emergency department (ED) presentation which identified paroxysmal afib and an acute coronary syndrome requiring emergency coronary angiogram. The angiogram revealed triple vessel disease potentially requiring Coronary Artery Bypass Grafting (CABG). However, a strong case was presented by the patient, for Percutaneous Coronary Intervention (PCI) over CABG, and a staged PCI strategy was decided. The first PCI stage was successful, however, numerous delays lead to an inpatient stay of 13 days and a transfer to another hospital for PCI intervention.  Conclusion: If proactive screening were undertaken, this ED attendance and extended hospital admission could likely have been avoided. Elevated blood pressure, lipids and HBA1C would be identified earlier and treatment started sooner, thus reducing risk factors. The HeartSciences wavECG indicated a repolarisation abnormality and an abnormal ECG, confirming a cardiology referral was required for an ECHO examination and which likely would lead to a CT Angio/Angio or cardiac MRI and if required PCI interventions managed electively as 1-3 days in hospital. Combining clinician skill, POC testing, patient education and AI analysis help predict cardiovascular risks, leading to opportunities for early intervention, and subsequently reducing the number of acute emergency admissions. The implications/benefits of incorporating this proactive screening service include potential reductions in healthcare costs, improved patient outcomes, and enhanced awareness of cardiovascular health. While limitations, such as potential biases and technological constraints, were acknowledged, the case study ultimately emphasizes the crucial role of integrating AI-enabled technology into proactive cardiovascular screening services to predict and prevent acute emergency admissions effectively.

Determining whether morphological trends in fossil species represent evolution within a lineage or lateral shifts in morphologically variable populations through time requires a thorough examination of the details of both morphology and paleoenvironment in time and space. The purpose of this study is to explore at high resolution the relationship between morphology of the trilobite Flexicalymene granulosa and paleoenvironmental conditions in Upper Ordovician deposits of southwestern Ohio and northern Kentucky. This is achieved by using geometric morphometrics to measure high-resolution morphological changes and by using gradient analysis to capture environmental gradients underlying faunal distribution patterns. Quantitatively comparing the outcomes of these two techniques provides an assessment of whether shape changes relates to environment. Results indicate that a significant amount of shape change, seen as an anteromedial movement of the eye region over time, corresponds to ordination scores. This suggests a relationship between certain aspects of morphology and environment. The combination of these quantitative techniques has provided the foundation for determining whether morphological trends within F. granulosa represent evolution or temporal shifts in geographic variation. Future work will involve examining this relationship in greater detail both geographically and stratigraphically.