Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
17
result(s) for
"Wells, Benedict"
Sort by:
Harding beats St. Benedict -- Eagles keep up the pressure but finally taste defeat
In the first quarter, Mack (senior) ran 16 yards for the first Lions score. Will Patterson (6-9-74-1), also a senior, hit senior [Todd Cox] for a 51-yard TD that seemed to have St. Benedict on the ropes early. [Harding] added two more scores in the second quarter on a 13-yard run by [Cortez Mack] and a 53- yard run by Patterson. [Nick Namias] hit sophomore Johnny Lawrence for a nine-yard TD early in the quarter. After strong defensive play by the Eagles, Namias jetted 39 yards to cut the Harding margin to two scores.
Newspaper Article
Roger Eberhard : standard
For his latest conceptual art project, Swiss photographer Roger Eberhard has travelled five continents and visited 32 cities where he booked the standard double room at the local Hilton hotel. He took a picture of the room's interior, always using the same perspective, and of the vista from its window. Eberhard's new book Standard, which has emerged from the project, offers a fresh and manifold view of a globalized world. The world's largest chain of hotels maintains a remarkably uniform design for its rooms and their furnishing and decoration truly a standard. Yet many of the rooms Eberhard has seen show a slight influence by local taste. His very particular urban panorama reveals how similar-perhaps exchangeable-the big cities around the globe have become in many aspects and at the same time have kept some of their characteristics. Three essays complement Eberhard's photography in this book. In a new original text German novelist Benedict Wells reflects on the monotony he experiences on reading tours staying in successions of hotel rooms. Franziska Solte, scholar of art history, examines the hotel room as the modern interior par excellence. And photo expert Nadine Wietlisbach analyses and contextualizes Eberhard's latest work.
Book
St. Benedict bashes Red Knights armor
A revitalized St. Benedict football team took advantage of three Bishop Byrne turnovers and defeated the Red Knights 23-3 in Whitehaven. The 2-0 Eagles were led by senior quarterback Nick Namias, who rushed for 101 yards on 23 carries and threw for 67 yards and no interceptions. Senior running back Nick Distretti also contributed 71 yards to the Eagles' 173 total rushing yards. photo; ; CSBA senior defensive end [Jake Bennett] recovers the third Bishop Byrne fumble of the night to set up the Eagles last touchdown scored by Nick Distretti.
Newspaper Article
St. Benedict Eagles win again
In the second quarter, senior defensive back Nick Distretti intercepted a Trojan pass setting up a Namias 37-yard pass to senior Doug Taylor. [Nick Namias] threw to receiver Lucian Godwin for a 13-yard TD and [John Nollner] contributed the extra point. SBEC rallied back for a 63- yard interception return and score and extra point. This was followed by a Namias 18-yard keeper to put SBA on top and Nollner added the extra point to give the Eagles the lead at the halftime, 17-13.
Newspaper Article
Evolution of Cancer Vaccines—Challenges, Achievements, and Future Directions
The development of cancer vaccines has been intensively pursued over the past 50 years with modest success. However, recent advancements in the fields of genetics, molecular biology, biochemistry, and immunology have renewed interest in these immunotherapies and allowed the development of promising cancer vaccine candidates. Numerous clinical trials testing the response evoked by tumour antigens, differing in origin and nature, have shed light on the desirable target characteristics capable of inducing strong tumour-specific non-toxic responses with increased potential to bring clinical benefit to patients. Novel delivery methods, ranging from a patient’s autologous dendritic cells to liposome nanoparticles, have exponentially increased the abundance and exposure of the antigenic payloads. Furthermore, growing knowledge of the mechanisms by which tumours evade the immune response has led to new approaches to reverse these roadblocks and to re-invigorate previously suppressed anti-tumour surveillance. The use of new drugs in combination with antigen-based therapies is highly targeted and may represent the future of cancer vaccines. In this review, we address the main antigens and delivery methods used to develop cancer vaccines, their clinical outcomes, and the new directions that the vaccine immunotherapy field is taking.
Journal Article
Dialysis Water Supply Faucet as Reservoir for Carbapenemase-Producing Pseudomonas aeruginosa
During June 2017–November 2019, a total 36 patients with carbapenem-resistant Pseudomonas aeruginosa harboring Verona-integron–encoded metallo-β-lactamase were identified in a city in western Texas, USA. A faucet contaminated with the organism, identified through environmental sampling, in a specialty care room was the likely source for infection in a subset of patients.
Journal Article
Molecular profiling supports the role of epithelial-to-mesenchymal transition (EMT) in ovarian cancer metastasis
Background
While metastasis ranks among the most lethal of all cancer-associated processes, on the molecular level, it remains one of the least well understood. One model that has gained credibility in recent years is that metastasizing cells at least partially recapitulate the developmental process of epithelial-to-mesenchymal transition (EMT) in their transit from primary to metastatic sites. While experimentally supported by cell culture and animal model studies, the lack of unambiguous confirmatory evidence in cancer patients has led to persistent challenges to the model’s relevance in humans.
Methods
Gene expression profiling (Affymetrix, U133) was carried out on 14 matched sets of primary (ovary) and metastatic (omentum) ovarian cancer (serous adenocarcinoma) patient samples. Hierarchical clustering and functional pathway algorithms were used in the data analysis.
Results
While histological examination reveled no morphological distinction between the matched sets of primary and metastatic samples, gene expression profiling clearly distinguished two classes of metastatic samples. One class displayed expression patterns statistically indistinguishable from primary samples isolated from the same patients while a second class displayed expression patterns significantly different from primary samples. Further analyses focusing on genes previously associated with EMT clearly distinguished the primary from metastatic samples in all but one patient.
Conclusion
Our results are consistent with a role of EMT in most if not all ovarian cancer metastases and demonstrate that identical morphologies between primary and metastatic cancer samples is insufficient evidence to negate a role of EMT in the metastatic process.
Journal Article
Molecular profiling supports the role of epithelial-to-mesenchymal transition (EMT) in ovarian cancer metastasis
Background While metastasis ranks among the most lethal of all cancer-associated processes, on the molecular level, it remains one of the least well understood. One model that has gained credibility in recent years is that metastasizing cells at least partially recapitulate the developmental process of epithelial-to-mesenchymal transition (EMT) in their transit from primary to metastatic sites. While experimentally supported by cell culture and animal model studies, the lack of unambiguous confirmatory evidence in cancer patients has led to persistent challenges to the model's relevance in humans. Methods Gene expression profiling (Affymetrix, U133) was carried out on 14 matched sets of primary (ovary) and metastatic (omentum) ovarian cancer (serous adenocarcinoma) patient samples. Hierarchical clustering and functional pathway algorithms were used in the data analysis. Results While histological examination reveled no morphological distinction between the matched sets of primary and metastatic samples, gene expression profiling clearly distinguished two classes of metastatic samples. One class displayed expression patterns statistically indistinguishable from primary samples isolated from the same patients while a second class displayed expression patterns significantly different from primary samples. Further analyses focusing on genes previously associated with EMT clearly distinguished the primary from metastatic samples in all but one patient. Conclusion Our results are consistent with a role of EMT in most if not all ovarian cancer metastases and demonstrate that identical morphologies between primary and metastatic cancer samples is insufficient evidence to negate a role of EMT in the metastatic process. Keywords: Metastasis, Epithelial-to-mesenchymal transition, EMT, Ovarian cancer
Journal Article