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The Cambridge companion to theatre history
\"Scholars, amateur historians and actors have shaped theatre history in different ways at different times and in different places. This Companion offers students and general readers a series of accessible and engaging essays on the key aspects of studying and writing theatre history. The diverse international team of contributors investigates how theatre history has been constructed, showing how historical facts are tied to political and artistic agendas and explaining why history matters to us\"-- Provided by publisher.
Book
On Being a Twenty-First-Century Theatre Historian
This series of provocations on the changing work of theatre historians opens with a contribution by David Wiles, who recounts a meeting of IFTR's Theatre Historiography Working Group in London in 2018. Wiles's reflection is followed by responses from scholars working in or on different regions, including perspectives by Oscar Tantoco Serquiña, Jr (Philippines), Lorena Verzero (Latin America) and Promona Sengupta (India).
Journal Article
The Cambridge Companion to Theatre History
Scholars, amateur historians and actors have shaped theatre history in different ways at different times and in different places. This Companion offers students and general readers a series of accessible and engaging essays on the key aspects of studying and writing theatre history. The diverse international team of contributors investigates how theatre history has been constructed, showing how historical facts are tied to political and artistic agendas and explaining why history matters to us. Beginning with an introduction to the central narrative that traditionally informs our understanding of what theatre is, the book then turns to alternative points of view - from other parts of the world and from the perspective of performers in fields such as music-theatre and circus. It concludes by looking at how history is written in the 'democratic' age of the Internet and offers a new perspective on theatre history in our globalised world.
eBook
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples
Light sheet fluorescence microscopy (LSFM) of optically cleared biological samples represents a powerful tool to analyze the 3-dimensional morphology of tissues and organs. Multimodal combinations of LSFM with additional analyses of the identical sample help to limit the consumption of restricted specimen and reduce inter-sample variation. Here, we demonstrate the
proof-of-concept
that LSFM of cleared brain tissue samples can be combined with Matrix Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging (MALDI-MSI) for detection and quantification of proteins. Samples of freshly dissected murine brain and of archived formalin-fixed paraffin-embedded (FFPE) human brain tissue were cleared (3DISCO). Tissue regions of interest were defined by LSFM and excised, (re)-embedded in paraffin, and sectioned. Mouse sections were coated with sinapinic acid matrix. Human brain sections were pre-digested with trypsin and coated with α-cyano-4-hydroxycinnamic acid matrix. Subsequently, sections were subjected to MALDI-time-of-flight (TOF)-MSI in mass ranges between 0.8 to 4 kDa (human tissue sections), or 2.5–25 kDa (mouse tissue sections) with a lateral resolution of 50 µm. Protein- and peptide-identities corresponding to acquired MALDI-MSI spectra were confirmed by parallel liquid chromatography tandem mass spectrometry (LC–MS/MS) analysis. The spatial abundance- and intensity-patterns of established marker proteins detected by MALDI-MSI were also confirmed by immunohistochemistry.
Journal Article
Variation in PTX3 Is Associated with Primary Graft Dysfunction after Lung Transplantation
Elevated long pentraxin-3 (PTX3) levels are associated with the development of primary graft dysfunction (PGD) after lung transplantation. Abnormalities in innate immunity, mediated by PTX3 release, may play a role in PGD pathogenesis.
Our goal was to test whether variants in the gene encoding PTX3 are risk factors for PGD.
We performed a candidate gene association study in recipients from the multicenter, prospective Lung Transplant Outcomes Group cohort enrolled between July 2002 and July 2009. The primary outcome was International Society for Heart and Lung Transplantation grade 3 PGD within 72 hours of transplantation. Targeted genotyping of 10 haplotype-tagging PTX3 single-nucleotide polymorphisms (SNPs) was performed in lung transplant recipients. The association between PGD and each SNP was evaluated by logistic regression, adjusting for pretransplantation lung disease, cardiopulmonary bypass use, and population stratification. The association between SNPs and plasma PTX3 levels was tested across genotypes in a subset of recipients with idiopathic pulmonary fibrosis.
Six hundred fifty-four lung transplant recipients were included. The incidence of PGD was 29%. Two linked 5' region variants, rs2120243 and rs2305619, were associated with PGD (odds ratio, 1.5; 95% confidence interval, 1.1 to 1.9; P = 0.006 and odds ratio, 1.4; 95% confidence interval, 1.1 to 1.9; P = 0.007, respectively). The minor allele of rs2305619 was significantly associated with higher plasma PTX3 levels measured pretransplantation (P = 0.014) and at 24 hours (P = 0.047) after transplantation in patients with idiopathic pulmonary fibrosis.
Genetic variants of PTX3 are associated with PGD after lung transplantation, and are associated with increased PTX3 plasma levels.
Journal Article
Translating Greek Theatre
Brides still wear veils today, so the first simile survives. sailing, however, is a minority pursuit, so the second simile is truncated. happily, the translators have no obscure mythology to deal with in this passage, but it is hard for them to give much resonance to the word \"prophecy,\" since prophets and oracles play little part in the modern world. it would be easy to launch into a debate here about the pros and cons of privileging the source culture vis-à-vis the target culture, distancing versus familiarizing, but the cultural points I have noted concern poetry in general, not theatre in particular. the situation is complicated, in regard to performance, by the fact that supposed experts remain ignorant about vital aspects of the aeschylean original. Was the text spoken with everyday intonations, or was it intoned in a more formal and musical fashion? the greatest unsolved mystery is the chorus. it is almost impossible for us to envisage how masked actors danced in unison as they delivered comprehensibly a text of great poetic density. this leaves us in the predicament that the play has to be reinvented afresh for each performance.\\n this language not only saves its native speakers the need to ever learn a foreign language or recognize how other languages enshrine other ways of seeing the world, but also accords its native speakers little sense of identity or specialness. successful poetic texts are usually associated with a more localized form of english, like scots or irish, where the creation of a literary work has a distinctive cultural function. the Yorkshire poet ted hughes, for example, in his rendering of the wave simile-\"like a sea-squall / that heaps the ocean and piles towers / of thunder into the sunrise\"-finds words that capture the weight and physicality of the water.23 he is not prisoner to the southern iambic pentameter, and he speaks in a language that has not lost contact with the natural world.
Journal Article
Forum: Translating Greek Theatre
Wiles identifies the four categories of translation that the publishing market supports and analyzes some samples lines from a text within the stage version category to show what may be involved in making a translation \"stageworthy.\" He comments on six lines from Frederic Raphael and Kenneth MacLeish's version of Aeschylus' \"Oresteia.\"
Journal Article
Dietary intake of schizophrenic patients in Nithsdale, Scotland: case-control study
Men Women All Wilcoxon signed ranks test Estimated average requirements Intake/day Patients (n=17) Controls (n=17) Patients (n=13) Controls (n=13) Patients (n=30) Controls (n=30) Median difference (95% CI) P Men Women Energy (MJ) 11.84 (7.67-17.93) 14.19 (6.94-23.22) 8.87 (5.07-13.02) 9.99 (5.25-16.25) 9.71 (5.07-17.94) 11.98 (5.25-23.22) 2.06 (0.26-4.23) 0.04 9.40 * [dagger] 8.11 [dagger] Protein (g) 92.5 (65.1-157.4) 114.2 (74-633) 68.7 (38.4-104.2) 82.5 (40.5-142.2) 84.5 (38.4-157.4) 96.0 (40.5-633.0) 15.9 (1.1 to 32.8) 0.07 44.4 â[euro]¡ 36.0 Total fibre (g) 13.0 (8.5-20.8) 22.0 (8.7-86.2) 10.7 (7.3-18.0) 15.5 (10.7-22.9) 12.6 (7.3-20.8) 18.9 (8.7-86.2) 7.0 (3.6 to 10.6) 0.0001 18 â[euro]¡ 18 â[euro]¡ Retinol (μg) 647 (294-1498) 817 (134-12 341) 533 (288-7556) 817 (201-11 585) 590 (288-7556) 817 (134-12 341) 310 (93 to 1269) 0.02 500 § 400 § Carotene (μg) 783 (219-3638) 2510 (523-11 313) 2048 (550-4657) 3079 (956-6188) 1443 (219-4657) 2798 (523-11 313) 1376 (549 to 2452) 0.004 - - Vitamin C (mg) 41.0 (4.0-204) 81.0 (14.0-262) 40.0 (3-165) 61.0 (27.0-291.0) 40.5 (3.0-204) 80.5 (14.0-219) 33.5 (2.0 to 64.0) 0.03 25 § 25 § Vitamin E (mg) 4.8 (3.4-18.0) 10.26 (2.23-32.0) 4.5 (2.3-6.0) 5.38 (3.6-14.7) 4.7 (2.3-18.0) 7.8 (2.2-32.0) 2.9 (1.45 to 5.35) 0.0002 7 [dagger] 5 [dagger] Alcohol (g) 3.8 (0-19.4).
Journal Article