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External Ear Malformations (EEM) continue to be a common malformation seen in the pediatric patient population. This study aims to further elucidate the correlation between EEM and cardiac and renal anomalies. A systematic review and meta-analysis to study the incidence of cardiac and renal anomalies associated with syndromic and isolated (EEM). The literature search spanned multiple databases, including Google Scholar, PubMed, Scopus, Web of Science, and MEDLINE. Studies must be focused on EEM and cardiac and/or renal anomalies. Only articles written in English were included. General study characteristics, number of EEM patients, number of cardiac and renal anomalies and whether cases were syndromic were extracted from the studies. Of 1,058 initial studies, 33 were included for meta-analyses. Mean JBI score for all included studies was 92.06%, indicating acceptable study quality. Interrater reliability was high, with a Cohen kappa score for all studies of 0.94. The resulting pooled prevalence of cardiac abnormalities was 20% [95% CI:13-28%], while renal abnormalities were 13% [95% CI: 7-20%]. The most common anomalies were VSD (3.725%) and renal agenesis (2.04%). The presence of syndrome data across studies was not a significant modifier of prevalence rates. Primary limitation is due to heterogeneity in individual study methodology and reporting standards. These results highlight a higher prevalence of cardiac-related conditions than renal anomalies in patients with both syndromic and non-syndromic EEM in the included studies, underscoring the need for thorough clinical evaluations.

External Ear Malformations (EEM) continue to be a common malformation seen in the pediatric patient population. This study aims to further elucidate the correlation between EEM and cardiac and renal anomalies. A systematic review and meta-analysis to study the incidence of cardiac and renal anomalies associated with syndromic and isolated (EEM). The literature search spanned multiple databases, including Google Scholar, PubMed, Scopus, Web of Science, and MEDLINE. Of 1,058 initial studies, 33 were included for meta-analyses. Mean JBI score for all included studies was 92.06%, indicating acceptable study quality. Interrater reliability was high, with a Cohen kappa score for all studies of 0.94. The resulting pooled prevalence of cardiac abnormalities was 20% [95% CI:13-28%], while renal abnormalities were 13% [95% CI: 7-20%]. The most common anomalies were VSD (3.725%) and renal agenesis (2.04%). The presence of syndrome data across studies was not a significant modifier of prevalence rates. These results highlight a higher prevalence of cardiac-related conditions than renal anomalies in patients with both syndromic and non-syndromic EEM in the included studies, underscoring the need for thorough clinical evaluations.

External Ear Malformations (EEM) continue to be a common malformation seen in the pediatric patient population. This study aims to further elucidate the correlation between EEM and cardiac and renal anomalies. A systematic review and meta-analysis to study the incidence of cardiac and renal anomalies associated with syndromic and isolated (EEM). The literature search spanned multiple databases, including Google Scholar, PubMed, Scopus, Web of Science, and MEDLINE. Of 1,058 initial studies, 33 were included for meta-analyses. Mean JBI score for all included studies was 92.06%, indicating acceptable study quality. Interrater reliability was high, with a Cohen kappa score for all studies of 0.94. The resulting pooled prevalence of cardiac abnormalities was 20% [95% CI:13-28%], while renal abnormalities were 13% [95% CI: 7-20%]. The most common anomalies were VSD (3.725%) and renal agenesis (2.04%). The presence of syndrome data across studies was not a significant modifier of prevalence rates. These results highlight a higher prevalence of cardiac-related conditions than renal anomalies in patients with both syndromic and non-syndromic EEM in the included studies, underscoring the need for thorough clinical evaluations.

Tissue Engineering (TE) is a newer technology with ongoing development across various areas of healthcare. For microtia patients, TE holds promise as a viable option for ear reconstruction, making it essential to understand the perspectives of patients and guardians. This study aimed to evaluate the perspectives of microtia patients and guardians, specifically investigating levels of awareness, comprehension, and interest in TE. A survey and educational material were distributed to microtia patients and guardians. Surveyors were assessed on a Likert scale, and comparative analyses, including two-sample t-testing and multivariate analysis with logistic regression, were used to observe trends in responses. A total of 40 surveys were recorded. White patients reported greater familiarity with TE. More than half of the respondents expressed an interest in TE as a reconstructive option. Having a doctor provide TE information positively correlated with willingness to adopt TE reconstruction. Understanding of TE positively correlated with willingness to pursue TE for reconstruction. Patients with more severe grade microtia and white patients were more likely to travel to a hospital that offered TE. We found that TE is an unfamiliar concept for most patients. Demographic, socioeconomic, cost, and trust in a doctor played an essential role in patients' and guardians' willingness to choose TE for microtia reconstruction. As TE for reconstruction approaches clinical use, these key considerations from a patient and family-centered lens about TE-based reconstruction is critical for application.

Tissue Engineering (TE) is a newer technology with ongoing development across various areas of healthcare. For microtia patients, TE holds promise as a viable option for ear reconstruction, making it essential to understand the perspectives of patients and guardians. This study aimed to evaluate the perspectives of microtia patients and guardians, specifically investigating levels of awareness, comprehension, and interest in TE. A survey and educational material were distributed to microtia patients and guardians. Surveyors were assessed on a Likert scale, and comparative analyses, including two-sample t-testing and multivariate analysis with logistic regression, were used to observe trends in responses. A total of 40 surveys were recorded. White patients reported greater familiarity with TE. More than half of the respondents expressed an interest in TE as a reconstructive option. Having a doctor provide TE information positively correlated with willingness to adopt TE reconstruction. Understanding of TE positively correlated with willingness to pursue TE for reconstruction. Patients with more severe grade microtia and white patients were more likely to travel to a hospital that offered TE. We found that TE is an unfamiliar concept for most patients. Demographic, socioeconomic, cost, and trust in a doctor played an essential role in patients' and guardians' willingness to choose TE for microtia reconstruction. As TE for reconstruction approaches clinical use, these key considerations from a patient and family-centered lens about TE-based reconstruction is critical for application.

Tissue Engineering (TE) is a newer technology with ongoing development across various areas of healthcare. For microtia patients, TE holds promise as a viable option for ear reconstruction, making it essential to understand the perspectives of patients and guardians. This study aimed to evaluate the perspectives of microtia patients and guardians, specifically investigating levels of awareness, comprehension, and interest in TE. A survey and educational material were distributed to microtia patients and guardians. Surveyors were assessed on a Likert scale, and comparative analyses, including two-sample t-testing and multivariate analysis with logistic regression, were used to observe trends in responses. A total of 40 surveys were recorded. White patients reported greater familiarity with TE. More than half of the respondents expressed an interest in TE as a reconstructive option. Having a doctor provide TE information positively correlated with willingness to adopt TE reconstruction. Understanding of TE positively correlated with willingness to pursue TE for reconstruction. Patients with more severe grade microtia and white patients were more likely to travel to a hospital that offered TE. We found that TE is an unfamiliar concept for most patients. Demographic, socioeconomic, cost, and trust in a doctor played an essential role in patients' and guardians' willingness to choose TE for microtia reconstruction. As TE for reconstruction approaches clinical use, these key considerations from a patient and family-centered lens about TE-based reconstruction is critical for application.