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"Williams, Peter"
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The dwarf who moved : and other remarkable tales from a life in the law
\"New Zealand's pre-eminent criminal barrister looks back on his remarkable life and times. In his time as a criminal defence lawyer in the New Zealand courts, the late Sir Peter Williams QC saw it all. From the days when abortion, homosexuality and even telling fortunes could see a person hauled before the courts, to sensational cases of wrongful imprisonment and police corruption, he witnessed the defining moments in the evolution of our modern judicial and penal systems. In this rich and wise collection of memoir, anecdote and forensic analysis our pre-eminent courtroom advocate recalls the people (including Ronald Jorgensen, Arthur Allan Thomas, 'Mr Asia', James K Baxter, Winston Peters and many more) and the cases (both celebrated and obscure) that defined his remarkable career. Fearless, astute and compassionate, Peter Williams proves -- beyond reasonable doubt -- that truth is nearly always stranger than fiction. Peter Williams QC was New Zealand's best known criminal barrister. He appeared in some of the country's most celebrated and controversial trials, including the so-called ژMr Asia' case, the notorious Basset Road machinegun murders, the Arthur Allan Thomas appeal and the murder trial of World War II hero Peta Awatere. Made Queen's Counsel in 1987, he was appointed a Knight Companion of the New Zealand Order of Merit shortly before his death in June 2015\"--Page 4 of cover.
Book
AI, Analytics and a New Assessment Model for Universities
As the COVID-19 pandemic recedes, its legacy has been to disrupt universities across the world, most immediately in developing online adjuncts to face-to-face teaching. Behind these problems lie those of assessment, particularly traditional summative assessment, which has proved more difficult to implement. This paper models the current practice of assessment in higher education as influenced by ten factors, the most important of which are the emerging technologies of artificial intelligence (AI) and learning analytics (LA). Using this model and a SWOT analysis, the paper argues that the pressures of marketisation and demand for nontraditional and vocationally oriented provision put a premium on courses offering a more flexible and student-centred assessment. This could be facilitated through institutional strategies enabling assessment for learning: an approach that employs formative assessment supported by AI and LA, together with collaborative working in realistic contexts, to facilitate students’ development as flexible and sustainable learners. While literature in this area tends to focus on one or two aspects of technology or assessment, this paper aims to be integrative by drawing upon more comprehensive evidence to support its thesis.
Journal Article
Bach : a musical biography
\"J.S. Bach composed some of the best-loved and most moving music in Western culture. In this book Peter Williams revisits Bach's biography through the lens of this music. Reviewing all of Bach's music, collection by collection, to reveal the development of Bach's interests and priorities. While a great deal has been written about the composer's vocal works, Williams gives the keyboard music its proper emphasis, revealing it as crucial to Bach's biography, as a young organist and a mature composer, as a performer in public and teacher in private, and as a profound thinker in the language of music.\"-- book jacket.
Book
Human–AI Learning: Architecture of a Human–AgenticAI Learning System
The Ancient Greeks foresaw non-human automata and the power of dialogic learning, but Generative AI and AgenticAI afford the prospect of going beyond interlocutor to co-creator in an empowering partnership between learner and AI agent to address ‘whole person’ education. This exploratory study reviews existing conceptual models and implementations of learning with AI before proposing the novel and original architecture of a human–AgenticAI learning system. In this, the learner and human tutor are each supported by AI assistants, and an AI tutor coordinates the generation, presentation and assessment of adaptive learning activities requiring the partnership of learner and AI assistant in the co-creation of learning outcomes. The proposed model is significant for incorporating 21st-century skills in a diversity of realistic learning environments. It tracks a formative assessment pathway of the learner’s contribution to co-created outcomes through to the compilation of a summative achievement portfolio for external warranting. Although focused upon learning in universities, the model is transferable to other educational milieux.
Journal Article
A vector holographic optical trap
The invention of optical tweezers almost forty years ago has triggered applications spanning multiple disciplines and has also found its way into commercial products. A major breakthrough came with the invention of holographic optical tweezers (HOTs), allowing simultaneous manipulation of many particles, traditionally done with arrays of scalar beams. Here we demonstrate a vector HOT with arrays of digitally controlled Higher-Order Poincaré Sphere (HOPS) beams. We employ a simple set-up using a spatial light modulator and show that each beam in the array can be manipulated independently and set to an arbitrary HOPS state, including replicating traditional scalar beam HOTs. We demonstrate trapping and tweezing with customized arrays of HOPS beams comprising scalar orbital angular momentum and cylindrical vector beams, including radially and azimuthally polarized beams simultaneously in the same trap. Our approach is general enough to be easily extended to arbitrary vector beams, could be implemented with fast refresh rates and will be of interest to the structured light and optical manipulation communities alike.
Journal Article
Understanding Policing and Professional Practice
This book outlines the foundations for understanding modern policing. It is an essential introduction for all policing students and trainee police officers to the underpinning aspects of the profession, providing a clear understanding of how the police service is currently organised and how it fits into the wider criminal justice system. Students are encouraged to think critically and reflect upon core concepts such as policing by consent, police accountability, governance and professional standards, and it examines the challenges of policing an increasingly global, technical and diverse world.The Professional Policing Curriculum in Practice is a new series of books that match the requirements of the new pre-join policing qualifications. The texts reflect modern policing, are up-to-date and relevant, and grounded in practice. They reflect the challenges faced by new students, linking theory to real-life operational practice, while addressing critical thinking and other academic skills needed for degree-level study.
eBook
18FGTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer’s disease
ObjectiveNeurofibrillary tangles (NFTs), consisting of intracellular aggregates of the tau protein, are a pathological hallmark of Alzheimer’s disease (AD). Here we report the identification and initial characterization of Genentech Tau Probe 1 ([18F]GTP1), a small-molecule PET probe for imaging tau pathology in AD patients.MethodsAutoradiography using human brain tissues from AD donors and protein binding panels were used to determine [18F]GTP1 binding characteristics. Stability was evaluated in vitro and in vivo in mice and rhesus monkey. In the clinic, whole-body imaging was performed to assess biodistribution and dosimetry. Dynamic [18F]GTP1 brain imaging and input function measurement were performed on two separate days in 5 β-amyloid plaque positive (Aβ+) AD and 5 β-amyloid plaque negative (Aβ-) cognitive normal (CN) participants. Tracer kinetic modeling was applied and reproducibility was evaluated. SUVR was calculated and compared to [18F]GTP1-specific binding parameters derived from the kinetic modeling. [18F]GTP1 performance in a larger cross-sectional group of 60 Aβ+ AD participants and ten (Aβ- or Aβ+) CN was evaluated with images acquired 60 to 90 min post tracer administration.Results[18F]GTP1 exhibited high affinity and selectivity for tau pathology with no measurable binding to β-amyloid plaques or MAO-B in AD tissues, or binding to other tested proteins at an affinity predicted to impede image data interpretation. In human, [18F]GTP1 exhibited favorable dosimetry and brain kinetics, and no evidence of defluorination. [18F]GTP1-specific binding was observed in cortical regions of the brain predicted to contain tau pathology in AD and exhibited low (< 4%) test-retest variability. SUVR measured in the 60 to 90-min interval post injection correlated with tracer-specific binding (slope = 1.36, r2 = 0.98). Furthermore, in a cross-sectional population, the degree of [18F]GTP1-specific binding increased with AD severity and could differentiate diagnostic cohorts.Conclusions[18F]GTP1 is a promising PET probe for the study of tau pathology in AD.
Journal Article