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"Wright, F"
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The seventeen second miracle
Cole Connor has become a patient teacher, and now he has invited three struggling teenagers to visit him on his front porch to learn about Rex Connor--and the Seventeen Second Miracle. Together they will learn how Rex Connor could have allowed seventeen seconds to destroy him, but instead he chose to live every day believing the smallest of acts could change the world for good.
Book
Global Trends in Atherosclerotic Cardiovascular Disease
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality, affecting over 523 million people globally. Atherosclerotic diseases, particularly ischemic heart disease (IHD) and stroke, are the primary mediators of CVD burden and trends, with half of CVD deaths attributed to IHD, and another quarter to ischemic stroke. The aim of this review was to provide an overview of world-wide trends in the burden of atherosclerotic CVD.
A literature review of published studies reporting regional or global trends or burden of CVD was undertaken, with a specific focus on atherosclerotic-mediated CVDs.
While long-term trends in age-standardized rates of CVD mortality and incidence indicate substantial declines in disease burden, the impact of population growth and ageing has contributed to a continued increase in the absolute number of people living with CVD. Additionally, when data are restricted to the most recent decade, there are indications that even declines in age-standardized CVD rates may have attenuated. Trends are also heterogeneous across countries and regions, with a relative increase in CVD burden in developing countries and differing trends within countries. The impact of the COVID-19 pandemic resulted in substantial short-term reductions in hospitalization rates for major atherosclerotic CVDs including acute coronary syndromes and heart failure in some countries.
Recent attenuation of declines in atherosclerotic CVDs with increasing absolute burden has significant implications for health systems and resource availability, with the impact of the COVID-19 pandemic on longer-term trends in CVD yet to be clearly established.
Journal Article
Epidemiology of cardiovascular disease in Europe
This Review presents data describing the health burden of cardiovascular disease (CVD) within and across the WHO European Region. CVD remains the most common cause of death in the region. Deaths from CVD in those aged <70 years, commonly referred to as premature, are a particular concern, with >60 million potential years of life lost to CVD in Europe annually. Although more women than men die from CVD, age-standardized rates of both morbidity and death are higher in men, and these differences in rates are greatest in individuals aged <70 years. Large inequalities in all measures of morbidity, treatment and mortality can be found between countries across the continent and must be a focus for improving health. Large differences also exist in the data available between countries. The development and implementation of evidence-based preventive and treatment approaches must be supported in all countries by consistent surveillance and monitoring, such that we can quantify the health burden of CVD as well as target interventions and provide impetus for action across Europe.In this Review, Townsend et al. describe the epidemiology of cardiovascular disease across the WHO European Region and call for improved surveillance and monitoring to inform the development and implementation of evidence-based preventive and treatment approaches.
Journal Article
Parrots of the wild : a natural history of the world's most captivating birds
\"A synthetic account of the diversity and ecology of wild parrots, distilling knowledge from the author's own research and from her review of more than 2,400 published scientific studies. The text covers parrots' evolutionary history, foraging, mating, and social behavior, innate intelligence, and conservation status. The book is enhanced by an array of illustrations, including photos of parrots taken exclusively in their natural habitat\"--Provided by publisher.
Book
Emotional and cognitive mechanisms of cyber-displaced aggression: exploring the impact of young adults’ victimization
This study aims to explore the mediation of revenge planning and anger rumination in the associations among face-to-face victimization, cyber victimization, and cyber-displaced aggression. Cyber-displaced aggression occurs when individuals direct their frustration towards innocent parties online due to an inability to retaliate directly. Data were collected from 489 young adults, between the ages of 18 and 25, from a university in the Midwestern United States. Measures included cyber and face-to-face victimization, cyber-displaced aggression, face-to-face displaced aggression, cyber victimization, emotional reactions, like anger rumination, and cognitive reactions, such as revenge planning. One year later, participants completed a questionnaire on cyber-displaced aggression. Results indicated that both forms of victimization predicted increased levels of cyber-displaced aggression one year later. Revenge planning and anger rumination significantly mediated these relationships. The findings underscore the importance of understanding emotional and cognitive factors in mitigating cyber-displaced aggression and inform strategies for reducing online aggression.
Journal Article
Genomewide association for schizophrenia in the CATIE study: results of stage 1
Little is known for certain about the genetics of schizophrenia. The advent of genomewide association has been widely anticipated as a promising means to identify reproducible DNA sequence variation associated with this important and debilitating disorder. A total of 738 cases with DSM-IV schizophrenia (all participants in the CATIE study) and 733 group-matched controls were genotyped for 492 900 single-nucleotide polymorphisms (SNPs) using the Affymetrix 500K two-chip genotyping platform plus a custom 164K fill-in chip. Following multiple quality control steps for both subjects and SNPs, logistic regression analyses were used to assess the evidence for association of all SNPs with schizophrenia. We identified a number of promising SNPs for follow-up studies, although no SNP or multimarker combination of SNPs achieved genomewide statistical significance. Although a few signals coincided with genomic regions previously implicated in schizophrenia, chance could not be excluded. These data do not provide evidence for the involvement of any genomic region with schizophrenia detectable with moderate sample size. However, a planned genomewide association study for response phenotypes and inclusion of individual phenotype and genotype data from this study in meta-analyses hold promise for eventual identification of susceptibility and protective variants.
Journal Article
Sports Stars Brazil in children with autism spectrum disorder: A feasibility randomized controlled trial protocol
Autism Spectrum Disorder (ASD) children have lower levels of participation in recreational and sporting activities when compared to their peers. Participation has been defined based on the Family of Participation-Related Constructs (fPRC) which defines participation as including both attendance and involvement, with sense of self, preferences and activity competence related to a child's participation. Modified sports interventions such as Sports Stars can act on physical literacy and some of the fPRCs components. This study aims to assess the feasibility of the Sports Stars Brazil intervention for children with ASD. This study will be conducted with 36 participants with ASD aged 6 to 12 years old following the CONSORT for pilot and feasibility recommendation. Participants will be randomly allocated into two groups. Intervention group will receive eight, weekly Sports Stars sessions. Each session will include of sports-focused gross motor activity training, confidence building, sports-education and teamwork development. Study assessments will occur at baseline, immediately post-intervention and 20-weeks post-randomization. First, we will assess process feasibility measures: recruitment, assessment completion, adherence, adverse events and satisfaction. Second, we will investigate the scientific feasibility of the intervention by estimating the effect size and variance at the level of achievement sports-related activity and physical activity participation goals (Goal Attainment Scaling), activity competence (Ignite Challenge, Test of Gross Motor Development-second edition, Physical Literacy Profile Questionnaire, Pediatric Disability Assessment Inventory-Computer Adaptive Test-PEDI-CAT-mobility, 10x5 Sprint Test and Muscle Power Sprint Test), sense of self (PEDI-CAT-responsibility), and overall participation at home, school and community, (Participation and Environment Measure for children and young people, PEM-CY). The results of this feasibility study will inform which components are critical to planning and preparing a future RCT study, aiming to ensure that the RCT will be feasible, rigorous and justifiable.
Journal Article