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\"With the theories and rules of electricity markets developing rapidly, it's difficult for beginners to start learning and difficult for those in the field to keep up. Bringing together information previously scattered among various journals and scholarly articles, this book provides a comprehensive overview of the current state of development in the electricity market. It introduces the fundamental principles of power system operation so that even those with a basic understanding can benefit from the book. It includes a series of consistent mathematical models of market operation of power systems, original cases, and MATLAB programming examples with solutions\"-- Provided by publisher.

A brighter near-infrared (NIR) phosphor is achieved by inhibiting the oxidation of Cr3+ and reducing the surface defects of phosphor particles, enabling the realization of smarter and more sensitive light sources for night vision.

Photovoltaic power generation is a promising method for generating electricity with a wide range of applications and development potential. It primarily utilizes solar energy and offers sustainable development, green environmental benefits, and abundant solar energy resources. However, there are many external factors that can affect the output characteristics of Photovoltaic cells and the effectiveness of the grid-connected control system. This study describes the introduction of Modular Multilevel Converter (MMC) technology into photovoltaic power generation systems to improve power generation efficiency. It proposes optimizing and improving the technology by adjusting the temperature and magnitude of lighting and combining traditional algorithms to propose a composite control algorithm. The photovoltaic power generation system employs the modular multi-level converter technology to enhance power generation efficiency alongside optimization and improvement. The temperature and size of light are regulated alongside the traditional algorithm to introduce the composite control algorithm. The improved composite algorithm surpasses the traditional one after experimental comparison of the results. The testing of a model photovoltaic power grid-connected system shows that the combination of modular multi-level converter technology and a photovoltaic grid-connected system, incorporating composite proportional integral control and quasi-proportional resonant control algorithms, yields improved results and feasibility. With rationality and effective control. The simulation results show that at 0.5 s, the light intensity suddenly increases from 750 to 1000 W/m 2 , and the direct-current voltage suddenly increases for a short time, but then decreases rapidly and finally returns to a stable level close to the rated voltage. From this, it can be seen that when the light intensity continues to change, the voltage value on the direct-current bus side of this MMC grid-tied photovoltaic system can still be maintained close to the rated value, ensuring the operational stability of the entire system. Sensibly and effectively controlled. The implementation of MMC technology in photovoltaic power generation systems enhances power generation efficiency, whilst simultaneously supporting the advancement of photovoltaic power generation and contributing towards environmental protection in the long term.

Microbially mediated anaerobic oxidation of methane (AOM) is a key process in the regulation of methane emissions to the atmosphere. Iron can serve as an electron acceptor for AOM, and it has been suggested that Fe(III)-dependent AOM potentially comprises a major global methane sink. Although it has been proposed that anaerobic methanotrophic (ANME) archaea can facilitate this process, their active metabolic pathways have not been confirmed. Here we report the enrichment and characterisation of a novel archaeon in a laboratory-scale bioreactor fed with Fe(III) oxide (ferrihydrite) and methane. Long-term performance data, in conjunction with the 13 C- and 57 Fe-labelling batch experiments, demonstrated that AOM was coupled to Fe(III) reduction to Fe(II) in this bioreactor. Metagenomic analysis showed that this archaeon belongs to a novel genus within family Candidatus Methanoperedenaceae , and possesses genes encoding the “reverse methanogenesis” pathway, as well as multi-heme c -type cytochromes which are hypothesised to facilitate dissimilatory Fe(III) reduction. Metatranscriptomic analysis revealed upregulation of these genes, supporting that this archaeon can independently mediate AOM using Fe(III) as the terminal electron acceptor. We propose the name Candidatus “ Methanoperedens ferrireducens ” for this microorganism. The potential role of “ M. ferrireducens ” in linking the carbon and iron cycles in environments rich in methane and iron should be investigated in future research.

Treatments for osteoarthritis (OA) are designed to restore chondrocyte function and inhibit cell apoptosis. Previous studies have shown that activation of the glucagon-like peptide-1 receptor (GLP-1R) leads to anti-inflammatory and anti-apoptotic effects. However, the role of GLP-1R in the pathological process of OA is unclear. In present work, we aimed to demonstrate the potential effect of GLP-1R on chondrocytes and elucidate its underlying mechanisms. We found that activation of GLP-1R with liraglutide could protect chondrocytes against endoplasmic reticulum stress and apoptosis induced by interleukin (IL)-1β or triglycerides (TGs). These effects were partially attenuated by GLP-1R small interfering RNA treatment. Moreover, inhibiting PI3K/Akt signaling abolished the protective effects of GLP-1R by increase the apoptosis activity and ER stress. Activating GLP-1R suppressed the nuclear factor kappa-B pathway, decreased the release of inflammatory mediators (IL-6, tumor necrosis factor α), and reduced matrix catabolism in TG-treated chondrocytes; these effects were abolished by GLP-1R knockdown. In the end, liraglutide attenuated rat cartilage degeneration in an OA model of knee joints in vivo. Our results indicate that GLP-1R is a therapeutic target for the treatment of OA, and that liraglutide could be a therapeutic candidate for this clinical application.

Stress sensing is the basis of human-machine interface, biomedical engineering, and mechanical structure detection systems. Stress sensing based on mechanoluminescence (ML) shows significant advantages of distributed detection and remote response to mechanical stimuli and is thus expected to be a key technology of next-generation tactile sensors and stress recorders. However, the instantaneous photon emission in ML materials generally requires real-time recording with a photodetector, thus limiting their application fields to real-time stress sensing. In this paper, we report a force-induced charge carrier storage (FICS) effect in deep-trap ML materials, which enables storage of the applied mechanical energy in deep traps and then release of the stored energy as photon emission under thermal stimulation. The FICS effect was confirmed in five ML materials with piezoelectric structures, efficient emission centres and deep trap distributions, and its mechanism was investigated through detailed spectroscopic characterizations. Furthermore, we demonstrated three applications of the FICS effect in electronic signature recording, falling point monitoring and vehicle collision recording, which exhibited outstanding advantages of distributed recording, long-term storage, and no need for a continuous power supply. The FICS effect reported in this paper provides not only a breakthrough for ML materials in the field of stress recording but also a new idea for developing mechanical energy storage and conversion systems.Lung disease: Mechanoluminescence: stress-sensitive phosphors hold deep memoriesA material that records mechanical impacts and provides optical readouts at later dates shows promise for anti-counterfeiting devices and structural damage analysis. Phosphors, such as rare earth-doped silicates, can emit light in response to physical stress because they store charge carriers in easy-to-access energy states. Rong-Jun Xie from China’s Xiamen University and colleagues now report development of phosphors that release charges to less accessible ‘deep’ energy states after being stimulated mechanically. These carriers are retained in the deep states and then released on-demand as photon emissions following thermal treatments. The team demonstrated several applications for the new phosphors including sensors that can record signature traces and composite films that attach to vehicles to monitor for potential collisions.

Lately, the LHCb Collaboration reported the discovery of two new states in the B+→D+D-K+ decay, i.e., X0(2866) and X1(2904). In the present work, we study whether these states can be understood as D¯∗K∗ molecules from the perspective of their two-body strong decays into D-K+ via triangle diagrams and three-body decays into D¯∗Kπ. The coupling of the two states to D¯∗K∗ are determined from the Weinberg compositeness condition, while the other relevant couplings are well known. The obtained strong decay width for the X0(2866) state, in marginal agreement with the experimental value within the uncertainty of the model, hints at a large D¯∗K∗ component in its wave function. On the other hand, the strong decay width for the X1(2904) state, much smaller than its experimental counterpart, effectively rules out its assignment as a D¯∗K∗ molecule.

Persistent luminescence, long-lived emission from inorganic or organic materials after the cessation of excitation, receives considerable attention in the field of optoelectronics. Despite great achievements in the past decades, the performance of organic materials still lags behind their inorganic counterparts, which have thousands of years of history. This is largely caused by the limited understanding of the mechanisms involved in organic materials. Here we report trap-induced persistent luminescence (TIP) in organic host–guest materials, with controllable trap depths from 0.11 to 0.56 eV and tunable afterglow emission at wavelengths from 507 to 669 nm via energy level engineering. The TIP phenomenon in a typical TN@TPBi film lasts for more than 24 h, with additional energy stored at room temperature for over 1 week. It is found that the trap depth in TIP is probably determined by the energy gap between the lowest unoccupied molecular orbitals of the radical anions of the host and guest molecules, matching well with density functional theory calculations. TIP was also observed after electrical excitation, demonstrating the potential of exploiting the semiconductor features of the organic hosts. These results provide a fundamental principle to design metal-free organic emitters of persistent luminescence, thereby expanding their applications in fields such as medical delivery identification, semiconductor devices and imaging techniques. Tunable afterglow emission in the visible region is enabled by trap-induced persistent luminescence in organic host–guest materials, with controllable trap depths.

NaYF4:Ln3+, due to its outstanding upconversion characteristics, has become one of the most important luminescent nanomaterials in biological imaging, optical information storage, and anticounterfeiting applications. However, the large specific surface area of NaYF4:Ln3+ nanoparticles generally leads to serious nonradiative transitions, which may greatly hinder the discovery of new optical functionality with promising applications. In this paper, we report that monodispersed nanoscale NaYF4:Ln3+, unexpectedly, can also be an excellent persistent luminescent (PersL) material. The NaYF4:Ln3+ nanoparticles with surface-passivated core–shell structures exhibit intense X-ray-charged PersL and narrow-band emissions tunable from 480 to 1060 nm. A mechanism for PersL in NaYF4:Ln3+ is proposed by means of thermoluminescence measurements and host-referred binding energy (HRBE) scheme, which suggests that some lanthanide ions (such as Tb) may also act as effective electron traps to achieve intense PersL. The uniform and spherical NaYF4:Ln3+ nanoparticles are dispersible in solvents, thus enabling many applications that are not accessible for traditional PersL phosphors. A new 3-dimensional (2 dimensions of planar space and 1 dimension of wavelength) optical information-storage application is demonstrated by inkjet-printing multicolor PersL nanoparticles. The multicolor persistent luminescence, as an emerging and promising emissive mode in NaYF4:Ln3+, will provide great opportunities for nanomaterials to be applied to a wider range of fields.Core-shelled nanoparticles NaYF4:Ln3+@NaYF4 with multicolor narrow-band persistent luminescence enable a new multidimensional optical information-storage technology.

Exosomal microRNAs (miRNAs) have been suggested to participate in the pathogenesis of neuropsychiatric diseases, but their role in major depressive disorder (MDD) is unknown. We performed a genome-wide miRNA expression profiling of blood-derived exosomes from MDD patients and control subjects and revealed the top differentially expressed exosomal miRNA, i.e. hsa-miR-139-5p (upregulation), had good performance to differentiate between MDD patients and controls. Tail vein injection of blood exosomes isolated from MDD patients into normal mice caused their depressive-like behaviors as determined by the forced swimming, tail suspension, and novelty suppressed feeding tests, and injection of blood exosomes isolated from healthy volunteers into unpredictable mild stress (CUMS)-treated mice alleviated their depressive-like behaviors. CUMS mice also showed significantly increased blood and brain levels of exosomal miR-139-5p. Furthermore, the depressive-like behaviors in CUMS-treated mice were rescued by intranasal injection of miR-139-5p antagomir, suggesting that increased exosomal miR-139-5p levels may mediate stress-induced depression-like behavior in mice. Both exosome treatment and miR-139-5p antagomir treatment increased hippocampal neurogenesis in the CUMS-treated mice, and treatment of exosome from MDD patients decreased hippocampal neurogenesis in the normal mice. The role of miR-139-5p in neurogenesis was validated by in vitro experiments, demonstrating that miR-139-5p is a negative regulator for neural stem cell proliferation and neuronal differentiation. Our findings together suggest that exosomes from patients with major depression caused depressive-like behaviors in mice with involvement of miR-139-5p-regulated neurogenesis. Therefore, exosomal miRNAs are promising targets for the diagnosis and treatment of MDD.