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result(s) for
"Yadav, Chandra Shekhar"
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Malware Analysis in IoT & Android Systems with Defensive Mechanism
by
Singh, Jagendra
,
Kumar, Ravindra
,
Yadav, Chandra Shekhar
in
Automation
,
Communication
,
Computer viruses
2022
The Internet of Things (IoT) and the Android operating system have made cutting-edge technology accessible to the general public. These are affordable, easy-to-use, and open-source technology. Android devices connect to different IoT devices such as IoT-enabled cameras, Alexa powered by Amazon, and various other sensors. Due to the escalated growth of Android devices, users are facing cybercrime through their Android devices. This article aims to provide a comprehensive study of the IoT and Android systems. This article classifies different attacks on IoT and Android devices and mitigation strategies proposed by different researchers. The article emphasizes the role of the developer in secure application design. This article attempts to provide a relative analysis of several malware detection methods in the different environments of attacks. This study expands the awareness of certain application-hardening strategies applicable to IoT devices and Android applications and devices. This study will help domain experts and researchers to gain knowledge of IoT systems and Android systems from a security point of view and provide insight into how to design more efficient, robust, and comprehensive solutions. This article discusses different attack vectors and mitigation strategies available to both developers and in the open domain. Certain guidelines are also suggested for application and platform developers, as well as application databases (Google play store), to limit the risk of attack, and users can form their own defense with knowledge regarding keeping hardware and software updated and securing their system with a strong password.
Journal Article
Change Detection in Remote Sensing Image Data Comparing Algebraic and Machine Learning Methods
by
Sharma, Deepak
,
Gangadharan, Syam Machinathu Parambil
,
Singh, Jagendra
in
Aerial photography
,
Algebra
,
Algorithms
2022
Remote sensing technology has penetrated all the natural resource segments as it provides precise information in an image mode. Remote sensing satellites are currently the fastest-growing source of geographic area information. With the continuous change in the earth’s surface and the wide application of remote sensing, change detection is very useful for monitoring environmental and human needs. So, it is necessary to develop automatic change detection techniques to improve the quality and reduce the time required by manual image analysis. This work focuses on the improvement of the classification accuracy of the machine learning techniques by reviewing the training samples and comparing the post-classification comparison with the image differencing in the algebraic technique. Landsat data are medium spatial resolution data; that is why pixel-wise computation has been applied. Two change detection techniques have been studied by applying a decision tree algorithm using a separability matrix and image differencing. The first change detection, e.g., the separability matrix, is a post-classification comparison in which individual images are classified by a decision tree algorithm. The second change detection is, e.g., the image differencing change detection technique in which changed and unchanged pixels are determined by applying the corner method to calculate the threshold on the changing image. The performance of the machine learning algorithm has been validated by 10-fold cross-validation. The experimental results show that the change detection using the post-classification method produced better results when compared to the image differencing of the algebraic change detection technique.
Journal Article
Synthesis, characterization, quantum chemical modelling, molecular docking, in silico and in vitro assessment of 3-(2-bromo-5-fluorophenyl))-1-(thiophen-2-yl)prop-2-en-1-one
by
Khan, Abdul Rahman
,
Yadav, Chandra Shekhar
,
Ahmad, Naseem
in
631/114
,
639/638/11
,
639/638/630
2024
α,β-unsaturated carbonyl compounds have extensive applications in various fields, such as organic, inorganic, analytical, and biological. In the modern era, they offer excellent pharmacological application prospects and find widespread use in the pharmaceutical industry. The current study revealed the synthesis and characterization of a novel 3-(2-bromo-5-fluorophenyl)-1-(thiophen-2-yl) prop-2-en-1-one (CY3). In vitro their antimicrobial (
Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli, Staphylococcus aureus, and Acinetobacter baumannii
), antifungal (
Candida parapsilosis, Candida tropicalis, and Candida albicans
), cytotoxicity (
VERO and Hep-G2 cells
), in silico, and molecular docking analysis were also performed. The in-silico analysis evaluated the drug-likeness properties of the compound CY3 using various filtering rules, including Lipinski’s, Ghose filter, Veber, Egan, Muegge, and Medicinal Chemistry alerts such as Pan Assay Interference Structures (PAINS), Brenk, and Lead-likeness. Then, molecular docking studies performed using the AutoDock (AD4), Vina, and iGEMDOCK tools to determine the mechanism by which the CY3 compound interact with the bacterial strains. Here, five different receptors were selected, such as DNA gyrase, glucose 6-phosphate synthase (GlmS), dihydrofolate reductase (DHFR), dehydrosqualene synthase (DHSS), and undecaprenyl pyrophosphate synthase (UDPPS), for molecular docking analysis. The CY3 compound showed a good binding affinity with the two target proteins, DHFR and DHSS, respectively, with maximum binding energies of about − 7.07 and − 7.05 kcal/mol. The synthesized CY3 compound exhibited moderate antibacterial activity with a MIC value > 100 µg/mL against all five bacterial strains and moderate antifungal activity with a MIC value > 50 µg/mL against all three fungal strains. Drug-likeness analyses also support their favourable bioavailability.
Journal Article
Synthesis, characterization and bio-evaluation of novel series of pyrazoline derivatives as potential antifungal agents
by
Khan, Abdul Rahman
,
Chopra, Sidharth
,
Krishna, Atul
in
639/638/549
,
639/638/630
,
Antibacterial
2025
In this study, a series of novel α, β-unsaturated carbonyl compounds (
3a–j
) and their pyrazoline derivatives (
4a–e
and
5a–b
) were designed and successfully synthesized. All synthesized compounds were characterized using various spectroscopic techniques, including
1
H NMR,
13
C NMR, and mass spectrometry. The biological activity of these compounds was evaluated against five bacterial strains (
Pseudomonas aeruginosa
,
Klebsiella pneumoniae
,
Escherichia coli
,
Staphylococcus aureus
, and
Acinetobacter baumannii
) and three fungal strains (
Candida tropicalis
,
Candida parapsilosis
, and
Candida albicans
). The results revealed that compound (
4c
) exhibited potent antifungal activity with a minimum inhibitory concentration (MIC) of 6.25 µg/mL across all tested strains and zone of inhibition (ZOI) against
Candida albicans
is 27 mm. Furthermore, time kill kinetics of
Candida albicans
and haemolysis assays also perform in support of their antifungal activity. Additionally, all synthesized compounds were subjected to computational analysis using molecular descriptors, ADMET, molecular docking, and molecular dynamics to find protein-ligand interactions. Molecular docking studies indicated that the most effective antifungal compounds (
3h
and
4c
) exhibited binding energies of -8.76 and −8.44 kcal/mol for DHFR and −7.96 and −8.24 kcal/mol for NMT1, respectively. The obtained results revealed that these compounds exhibit potential interactions with antifungal targets as dual inhibitors. As a result, this study finds an important approach to synthesized compounds with potential antifungal activity.
Journal Article
Multi-Class Pixel Certainty Active Learning Model for Classification of Land Cover Classes Using Hyperspectral Imagery
by
Alzamil, Zamil S.
,
Pradhan, Monoj Kumar
,
Wechtaisong, Chitapong
in
Accuracy
,
Active learning
,
Adaptation
2022
An accurate identification of objects from the acquisition system depends on the clear segmentation and classification of remote sensing images. With the limited financial resources and the high intra-class variations, the earlier proposed algorithms failed to handle the sub-optimal dataset. The building of an efficient training set iteratively in active learning (AL) approaches improves classification performance. The heuristics-based AL provides better results with the inheritance of contextual information and the robustness to noise variations. The uncertainty exists pixel variations make the heuristics-based AL fail to handle the remote sensing image classification. Previously, we focused on the extraction of clear textural pattern information by using the extended differential pattern-based relevance vector machine (EDP-AL). This paper extends that work into the novel pixel-certainty activity learning (PCAL) based on the information about textural patterns obtained from the extended differential pattern (EDP). Initially, distributed intensity filtering (DIF) is used to eliminate noise from the image, and then histogram equalization (HE) is used to improve the image quality. The EDP is used to merge and classify different labels for each image sample, and this algorithm expresses the textural information. The PCAL technique is used to classify the HSI patterns that are important in remote sensing applications using this pattern collection. Pavia University and Indian Pines (IP) are the datasets used to validate the performance of the proposed PCAL (PU). The ability of PCAL to accurately categorize land cover types is demonstrated by a comparison of the proposed PCAL with existing algorithms in terms of classification accuracy and the Kappa coefficient.
Journal Article
Xeno-Estrogenic Pesticides and the Risk of Related Human Cancers
2022
In recent decades, “environmental xenobiotic-mediated endocrine disruption”, especially by xeno-estrogens, has gained a lot of interest from toxicologists and environmental researchers. These estrogen-mimicking chemicals are known to cause various human disorders. Pesticides are the most heavily used harmful xenobiotic chemicals around the world. The estrogen-mimicking potential of the most widely used organochlorine pesticides is well established. However, their effect is not as clearly understood among the plethora of effects these persistent xenobiotics are known to pose on our physiological system. Estrogens are one of the principal risk modifiers of various disorders, including cancer, not only in women but in men as well. Despite the ban on these xenobiotics in some parts of the world, humans are still at apparent risk of exposure to these harmful chemicals as they are still widely persistent and likely to stay in our environment for a long time owing to their high chemical stability. The present work intends to understand how these harmful chemicals may affect the risk of the development of estrogen-mediated human cancer.
Journal Article
Apple Sweetness Measurement and Fruit Disease Prediction Using Image Processing Techniques Based on Human-Computer Interaction for Industry 4.0
by
Chakraborty, Koushik
,
Kumar, Mohit
,
Tiwari, Basant
in
Agricultural production
,
Agriculture
,
Algorithms
2022
When it comes to agricultural sciences, one of the most difficult challenges to solve is the detection of diseases. Agricultural specialists study a variety of sources to detect plant issues on a regular basis. Rarely can misinterpretations of diseased plants cause improper pesticide selection and subsequent agricultural disaster, although this does happen from time to time. In order to diagnose illnesses at an early stage, it is necessary to deploy automated disease detection systems. This is critical for farmers since it is both time-consuming and expensive. A sick leaf must be carefully segmented in order to be properly separate it from the rest of the leaves. Despite digital noise, a different background, a different shape, and a different brightness, it is tough to distinguish a sick photo. In order to increase the quality of apple leaf images for disease detection and classification, a new approach known as brightness preserving dynamic fuzzy histogram equalisation (BPDFHE) has been created. To determine the sweetness of an apple, examine the leaf and the texture of the fruit. In the next section, the performance of the proposed enhancement algorithm is compared to the performance of existing enhancement approaches. Existing segmentation algorithms are outperformed by our approach for segmenting the area of interest from ill leaves against a live background. It is during this phase that we analyse the Jaccard index, the Dice coefficient, and correctness. Comparing the proposed segmentation algorithm to current approaches, it proves to be a highly effective strategy that can more efficiently identify apple ill leaves from a live background with a 99.8 percent accuracy rate.
Journal Article
Sentiment Analysis of Statements on Social Media and Electronic Media Using Machine and Deep Learning Classifiers
by
Krishna, Muddada Murali
,
Vankara, Jayavani
,
Khan, Mohammad Monirujjaman
in
Accuracy
,
Analysis
,
Data mining
2022
When it comes to our everyday life, emotions have a critical role to play. It goes without saying that it is critical in the context of mobile-computer interaction. In social and mobile communication, it is vital to understand the influence of emotions on the way people interact with one another and with the material they access. This study tried to investigate the relationship between the expressive state of mind and the efficacy of the human-mobile interaction while accessing a variety of different sorts of material over the course of learning. In addition, the difficulty of the feeling of many individuals is taken into account in this research. Human hardness is an important factor in determining a person’s personality characteristics, and the material that they can access will alter depending on how they engage with a mobile device. It analyzes the link between the human-mobile interaction and the person’s mental toughness to provide excellent suggestion material in the appropriate manner. In this study, an explicit feedback selection method is used to gather information on the emotional state of the mind of the participants. It has also been shown that the emotional state of a person’s mind influences the human-mobile connection, with persons with varying levels of hardness accessing a variety of various sorts of material. It is hoped that this research will assist content producers in identifying engaging material that will encourage mobile users to promote good content by studying their personality features.
Journal Article
Intelligent Classifier for Identifying and Managing Sheep and Goat Faces Using Deep Learning
by
Yadav, Chandra Shekhar
,
Peixoto, Antonio Augusto Teixeira
,
Rufino, Luis Alberto Linhares
in
Accuracy
,
Algorithms
,
Animal lactation
2024
Computer vision, particularly in artificial intelligence (AI), is increasingly being applied in various industries, including livestock farming. Identifying and managing livestock through machine learning is essential to improve efficiency and animal welfare. The aim of this work is to automatically identify individual sheep or goats based on their physical characteristics including muzzle pattern, coat pattern, or ear pattern. The proposed intelligent classifier was built on the Roboflow platform using the YOLOv8 model, trained with 35,204 images. Initially, a Convolutional Neural Network (CNN) model was developed, but its performance was not optimal. The pre-trained VGG16 model was then adapted, and additional fine-tuning was performed using data augmentation techniques. The dataset was split into training (88%), validation (8%), and test (4%) sets. The performance of the classifier was evaluated using precision, recall, and F1-Score metrics, with comparisons against other pre-trained models such as EfficientNet. The YOLOv8 classifier achieved 95.8% accuracy in distinguishing between goat and sheep images. Compared to the CNN and VGG16 models, the YOLOv8-based classifier showed superior performance in terms of both accuracy and computational efficiency. The results confirm that deep learning models, particularly YOLOv8, significantly enhance the accuracy and efficiency of livestock identification and management. Future research could extend this technology to other livestock species and explore real-time monitoring through IoT integration.
Journal Article
Total Hip Arthroplasty in Patients with Active Tuberculosis of the Hip with Advanced Arthritis
by
Yadav, Chandra Shekhar
,
Ashok Kumar
,
Neogi, Devdatta Suhas
in
Adult
,
Antitubercular Agents - therapeutic use
,
Arthritis - diagnostic imaging
2010
Osteoarticular tuberculosis (TB) in the hip and other joints is increasing and patients in developing countries commonly present with advanced joint destruction. We asked whether TB is reactivated after THA in these patients. We retrospectively reviewed 12 patients with an average age of 45 years who had advanced stages of hip destruction secondary to mycobacterium TB and who were treated with primary THA and prescribed perioperative antituberculous medication for 12 to 18 months postoperatively. Diagnosis in all these patients was confirmed by histopathology and culture. The minimum followup was 25 months (average, 41 months; range, 25–58 months). We observed no reactivation of TB in 11 patients who had Harris hip scores ranging from 86 to 97. One patient who postoperatively did not comply with the antituberculous chemotherapy had reactivation and superimposed infection through a nonhealing sinus tract; that patient underwent component removal and resection arthroplasty. When the infected tissue can be débrided and adequate antituberculous therapy is instituted the outcome of joint arthroplasty may not be adversely affected. THA in the tuberculous hip has a low risk of reactivation and produces good functional results.
Level of Evidence:
Level IV, therapeutic case series (no, or historical control group). See the Guidelines for Authors for a complete description of levels of evidence.
Journal Article