Explore the vast range of titles available.

Purpose Urge urinary incontinence (UUI) is a common postoperative symptom after the trans-obturator tape (TOT) procedure, often adversely affecting patients’ quality of life (QoL). This study aimed to identify the risk factors that increase the likelihood of UUI, with the goal of addressing these factors to enhance patients’ QoL. Material and Method This retrospective analysis included 365 women diagnosed with pure stress incontinence who underwent the TOT procedure from 2015 to 2023. Of these, 112 patients who developed UUI were classified as Group 1, while 253 patients without UUI were designated as Group 2. The study examined factors such as age, body mass index (BMI), number of births, delivery types, menopausal status, follow-up duration, recurrence of stress incontinence, meatal stenosis, post-void residual (PVR), Burch operation rate, and instances of recurrent UTIs. Quality of Life was assessed using the Incontinence QoL (I-QoL) questionnaire. Urge symptoms were evaluated through both a bladder diary (BD) and the Overactive Bladder Symptom Score (OABSS) questionnaire. Results Risk factors, including menopause (p = 0.013), increased BMI (p = 0.001), elevated PVR (p = 0.019), meatal stenosis (p = 0.038), and advanced age (p = 0.045), were significantly more prevalent in Group 1 compared to Group 2. Additionally, Group 1 had considerably lower I-QoL scores across all domains, suggesting substantial psychosocial and functional impairment (p < 0.001). Conclusion UUI following the TOT procedure is influenced by various modifiable and non-modifiable factors. Through comprehensive pre-operative and postoperative evaluations, high-risk patients can be identified, potentially reducing UUI symptoms and improving their QoL.

Purpose This study aims to assess the effect of pre‐stenting and bladder drainage on intrapelvic pressure (IP) during Retrograde Intrarenal Surgery (RIRS). Methods Eighty‐five consecutive patients were prospectively enrolled and meticulously recorded in a data form. Forty‐two patients meeting the inclusion criteria after applying exclusion factors. The patients were divided into two groups: Group 1 (21 patients with preoperative JJ stents) and Group 2 (21 patients without preoperative JJ stents). IP was measured during RIRS, and the impact of various factors, including pre‐stenting, bladder drainage and hydronephrosis (HN) grade, on IP was analysed through univariate and multiple linear regression. Results The perioperative mean highest IP (78 ± 18.2 mmHg vs. 110 ± 23.9 mmHg), median lowest IP (29 mmHg vs. 42 mmHg) and median overall IP (41 mmHg vs. 69 mmHg) were significantly lower in Group 1 compared to Group 2 (all p < 0.001). Multivariate analysis showed that pre‐stenting and mild HN (Grade 0–1) were independent predictors of reduced IP. Conclusion Pre‐stenting led to a significant reduction in IP during RIRS, likely due to passive ureteral dilation. Additionally, bladder drainage with urethral catheter further decreased IP. These findings suggest that pre‐stenting and bladder drainage should be considered as strategies to reduce IP during RIRS, potentially improving surgical outcomes.

Objective: To share our experience with retrograde intrarenal surgery (RIRS) done in patients with horseshoe kidney anomaly. Materials and Methods: Data from 107 patients who underwent RIRS for kidney stones between 2013 and 2016 in our clinic was retrospectively analyzed and 6 patients with horseshoe kidney anomaly detected on computed tomography (CT) were included in the study. Achieving stone-free status or having residual stones of ≤4 mm were considered operational success. Results: The mean age of the patients was 44.5±6.7 years. Four patients were male (66.6%) and two were female (33.3%). The mean stone size was 14.5±4.1 (10-22) mm. Three patients had pelvis stones (50%) and the rest 3 (50%) had lower calyx stones. Two patients (33.3%) were found to be stone-free on post-operative non-contrast CT results. Conclusion: RIRS should be performed by experienced surgeons in patients with horseshoe kidney.

Purpose Continuous oxygen therapy to compensate for decreased oxygen saturation in the blood is a life-saving treatment used in case lung involvement. Excess oxygen delivery was reported to be a common situation, in which about 50% of the patients showed hyperoxemia and 4% in severe hyperoxemia. In this work, we investigated the effects of hyperoxia on the rat kidneys and whether tadalafil has an effect to reduce this damage. Materials and methods Three groups of 8 male rats each weighing 300–350 g were formed. The groups were divided into the control group, hyperoxia group, and hyperoxia and tadalafil administered group for 10 days. At the end of the 10th day, blood and kidney samples were taken for biochemical analysis (SOD and NO levels) and histopathological examination. Results While our findings showed that SOD levels were significantly different among the control and experimental groups and within the experimental groups, no statistical difference was found in terms of NO levels among the groups (Table 1). While the glomerular and tubular injury was higher in the Hyperoxia group and the Hyperoxia + Tadalafil group than in the control group ( p  < 0.001), as a result of the rate of severe glomerular and tubular injury in the hyperoxia group, was 62.5% and 43.8% and in the group given tadalafil was 43.8% and 31.3%, respectively (Table 2). Conclusions Exposure to hyperoxia condition causes renal glomerular and tubular damage, and tadalafil does not show a protective effect on this damage according to this study’s dose and exposure time.

Amaç: Retrograd intrarenal cerrahi (RIRS) sırasında böbrek içinde basınç artışını gösteren çalışmalar olmakla birlikte preoperatif JJ stent takılmasının intrapelvik basınç üzerine etkisini gösteren çalışma yoktur. Biz bu çalışmada işlem öncesi JJ stent uygulamasının ve işlem sırasında üretral stent uygulamasının RIRS sırasında renal pelvis basıncına etkisini araştırdık. Gereç-Yöntem: Bu çalışmada 02.09.2019 ile 30.10.2021 tarihleri arasında kliniğimizde RIRS yapılmış toplam 85 hastanın verileri retrospektif olarak incelendi. Dışlama kriterleri sağlandıktan sonra 42 hasta çalışmada kaldı. Preoperatif JJ stent takılmış 21 hasta Grup 1’i oluştururken preoperatif JJ stent takılmamış 21 hasta Grup 2’yi oluşturdu. RIRS sırasında basınç verileri milimetre civa (mmHg) cinsinden üreter kataterinin distal ucu basınç dönüştürücü ile anestezi monitörüne bağlanarak ölçülmüş ve kaydedilmiş. Gruplar demografik, taş özellikleri, perioperatif sonuçlar ve basınç değerleri açısından karşılaştırıldı. İntrapelvik en yüksek basınç ve ortalama basıncı etkileyen faktörleri tespit etmek için multivaryant analiz yapıldı. Bulgular: Gruplar arasında yaş, cinsiyet, vücut kitle indeksi (VKİ), taraf, taş boyutu, taş lokalizasyonu, taş dansitesi açısından fark yoktu. Grup 2’de preoperatif hidronefroz SFU Grade 2-3 oranı Grup 1’e göre daha yüksek bulundu (p=0,045). İntrapelvik basınç karşılaştırmasında Grup 1’de tüm basınçlar Grup 2’ye göre daha düşük saptandı. Ortanca kontrol pelvis basıncı (Pc) Grup 1’de 7 mmHg (6-9 mmHg) iken Grup 2’de 9 mmHg (6-12 mmHg) idi (p<0,001). En yüksek pelvis basıncı (Ph) Grup 1’de 78±18,2 mmHg iken, Grup 2’de 110±23,9 mmHg idi (p<0,001). Ortanca en düşük pelvis basıncı (Pl) Grup 1’de 29 mmHg (19-54 mmHg) iken Grup 2’de 42 mmHg (17-65 mmHg) idi (p=0,001). Ortanca pelvis basıncı (Port) Grup 1’de 41 mmHg (28-70 mmHg) iken Grup 2’de 69 mmHg (35-96 mmHg) idi (p<0,001). Dolu mesanede ortalama pelvis basıncı (Pbf) Grup 1’de 46,7±10,9 mmHg iken Grup 2’de 70±16,9 mmHg idi (p<0,001). Boş mesanede ortalama pelvis basıncı (Pbe) Grup 1’de 40,2±12 mmHg iken Grup 2’de 61,3±14,7 mmHg idi (p<0,001). Üretral katater takılması ile ortanca pelvis basınç düşüşü (Pdec) Grup 1’de 8 mmHg (2-22 mmHg) iken Grup 2’de 8 mmHg (1-28 mmHg) idi ve gruplar iv arasında fark izlenmedi (p=0,909). Multivaryant analizde intrapelvik basıncın düşük olmasında JJ stentin ve Grade 0-1 hidronefroz varlığı bağımsız bir prediktif faktör olarak gösterildi. Sonuç: Sonuçlar değerlendirildiğinde, RIRS öncesi takılan JJ stentin yaptığı üreter dilatasyonu sayesinde perioperatif renal pelvis basıncını azalttığı gösterildi. Ayrıca işlem sırasında üretral katater ile mesane drenajının yapılması da perioperatif renal pelvis basıncını azalttığı gösterildi.