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"Yu, Li"
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The Chinese writing system in Asia : an interdisciplinary perspective
\"The Chinese Writing System in Asia: An Interdisciplinary Perspective integrates a diverse range of disciplinary approaches in examining how the Chinese script represents and actively shapes personal and social identities in and beyond Asia. It is an ideal read for students and scholars interested in a broad and culturally rich introduction to research on the Chinese writing system. It can also serve as the main text of an undergraduate course on the subject. Key features of this volume include: Insights from studies of the Chinese writing system in linguistics, script reform and technology, gender, identity, literature, and the visual arts; Examples embedded in inquiries of the cultural history and contemporary society of Asia; Rigorous yet accessible discussions of complex concepts and phenomena that assume no prior knowledge of Asian languages or linguistics; Supplementary multimedia materials and resources, including instructional support, available online\"-- Provided by publisher.
BOOK
Innovation and challenges of artificial intelligence technology in personalized healthcare
As the burgeoning field of Artificial Intelligence (AI) continues to permeate the fabric of healthcare, particularly in the realms of patient surveillance and telemedicine, a transformative era beckons. This manuscript endeavors to unravel the intricacies of recent AI advancements and their profound implications for reconceptualizing the delivery of medical care. Through the introduction of innovative instruments such as virtual assistant chatbots, wearable monitoring devices, predictive analytic models, personalized treatment regimens, and automated appointment systems, AI is not only amplifying the quality of care but also empowering patients and fostering a more interactive dynamic between the patient and the healthcare provider. Yet, this progressive infiltration of AI into the healthcare sphere grapples with a plethora of challenges hitherto unseen. The exigent issues of data security and privacy, the specter of algorithmic bias, the requisite adaptability of regulatory frameworks, and the matter of patient acceptance and trust in AI solutions demand immediate and thoughtful resolution .The importance of establishing stringent and far-reaching policies, ensuring technological impartiality, and cultivating patient confidence is paramount to ensure that AI-driven enhancements in healthcare service provision remain both ethically sound and efficient. In conclusion, we advocate for an expansion of research efforts aimed at navigating the ethical complexities inherent to a technology-evolving landscape, catalyzing policy innovation, and devising AI applications that are not only clinically effective but also earn the trust of the patient populace. By melding expertise across disciplines, we stand at the threshold of an era wherein AI's role in healthcare is both ethically unimpeachable and conducive to elevating the global health quotient.
Journal Article
Traditional Herbal Medicine: A Potential Therapeutic Approach for Adjuvant Treatment of Non-small Cell Lung Cancer in the Future
Lung carcinoma is the primary reason for cancer-associated mortality, and it exhibits the highest mortality and incidence in developed and developing countries. Non-small cell lung cancer (NSCLC) and SCLC are the 2 main types of lung cancer, with NSCLC contributing to 85% of all lung carcinoma cases. Conventional treatment mainly involves surgery, chemoradiotherapy, and immunotherapy, but has a dismal prognosis for many patients. Therefore, identifying an effective adjuvant therapy is urgent. Historically, traditional herbal medicine has been an essential part of complementary and alternative medicine, due to its numerous targets, few side effects and substantial therapeutic benefits. In China and other East Asian countries, traditional herbal medicine is increasingly popular, and is highly accepted by patients as a clinical adjuvant therapy. Numerous studies have reported that herbal extracts and prescription medications are effective at combating tumors. It emphasizes that, by mainly regulating the P13K/AKT signaling pathway, the Wnt signaling pathway, and the NF-κB signaling pathway, herbal medicine induces apoptosis and inhibits the proliferation and migration of tumor cells. The present review discusses the anti-NSCLC mechanisms of herbal medicines and provides options for future adjuvant therapy in patients with NSCLC.
Journal Article
The influence of physical activity on emotional management ability in college students: a chain mediating role of psychological resilience and health literacy
Objective
This study aimed to investigate the impact of physical activity (PA) on emotional management ability (EMA) in college students and to analyze the chain mediating roles of psychological resilience (PR) and health literacy (HL) in the relationship between PA and EMA.
Methods
Demographic information was collected using a stratified, cluster, and multi-stage sampling method. Data on PA, PR, HL, and EMA among college students were collected using an online questionnaire. A total of 13,590 valid questionnaires were obtained.
Results
A significant positive correlation was found between PA and EMA in college students (
r
= 0.177,
P
< 0.01). PR and HL played significant mediating roles in the relationship between PA and EMA. The mediation effect consisted of independent mediation by PR and HL and a chain mediation effect between the two. The values of the independent mediation effects and the chain mediation effect were 0.011, 0.010, and 0.004, respectively. The chain mediation effect was lower than each of the individual mediation effects and showed a statistically significant difference compared to the mediation effect of HL (
P
< 0.05).
Conclusion
PA significantly enhances college students’ EMA through direct effects and a chain mediation pathway involving PR and HL. Coordinated interventions, including regular exercise, PR training, and health education, are recommended to optimize college students’ psychological health.
Journal Article
Tuan yuan
Maomao's dad can only come back home once a year because of the work. In Chinese New Year, they have a good time for their family reunion.
Book
Enhanced diplopia detection and binocular single vision assessment through virtual reality: A comprehensive study
This study aimed to develop a novel virtual reality (VR)-based binocular single vision (BSV) testing system for the quantitative assessment of diplopia and to evaluate its diagnostic accuracy and stability through clinical research. We first developed a VR-based BSV testing apparatus (VR-BSVT) using Oculus Quest 2 VR glasses and Unity software. The system provides three parameters for assessing subjects’ binocular single vision function, and hence their diplopia: VR-BSVF (Virtual Reality-Based Binocular Single Vision Field area), VR-BSVD (Virtual Reality-Based Binocular Single Vision Distance), and VR-BAR (Virtual Reality-Based Binocular Single Vision Field area ratio). Subsequently, we conducted a clinical control study to systematically evaluate the accuracy and stability of VR-BSVT in the quantitative assessment of diplopia. In this comparative study, we recruited 31 visually healthy subjects and 35 patients diagnosed with diplopia. Each participant underwent two VR-BSVT assessments. The diagnostic accuracy of VR-BSVT in identifying diplopia was analyzed using receiver operating characteristic (ROC) curves, Spearman’s rank correlation coefficient, and Bland-Altman analyses. Intraclass correlation coefficient (ICC) was employed to measure the diagnostic stability of VR-BSVT. Through human-computer interaction, VR-BSVT could rapidly detect diplopia and assess binocular single vision function, allowing for the detection of diplopia at different test distances. Among the 66 individuals who participated in the study, results from Intraclass correlation coefficient (ICC) for different test distances showed no significant differences in VR-BAR measurements at both near and far distances between healthy volunteers and patients with diplopia (
P
= 0.988), indicating good stability of VR-BSVT in diagnosing diplopia. Additionally, the VR-BSVF and VR-BSVD metrics were significantly reduced in the diplopia group compared to the healthy controls (
P
< 0.01). ROC analysis indicated that VR-BSVT could accurately discriminate patients with diplopia.The Bland-Altman plot revealed a 95% agreement range spanning from − 17.70 to 22.86. These results suggest that VR-BSVT has good precision in diagnosing diplopia. The VR-BSVT developed in this study achieves rapid, accurate, and stable detection and assessment of clinical diplopia, and utilizes virtual reality technology to detect diplopia over a larger visual space. With its compactness and portability, VR-BSVT holds promise for facilitating home healthcare and telemedicine in the future.
Journal Article
Inflammation balance in skeletal muscle damage and repair
Responding to tissue injury, skeletal muscles undergo the tissue destruction and reconstruction accompanied with inflammation. The immune system recognizes the molecules released from or exposed on the damaged tissue. In the local minor tissue damage, tissue-resident macrophages sequester pro-inflammatory debris to prevent initiation of inflammation. In most cases of the skeletal muscle injury, however, a cascade of inflammation will be initiated through activation of local macrophages and mast cells and recruitment of immune cells from blood circulation to the injured site by recongnization of damage-associated molecular patterns (DAMPs) and activated complement system. During the inflammation, macrophages and neutrophils scavenge the tissue debris to release inflammatory cytokines and the latter stimulates myoblast fusion and vascularization to promote injured muscle repair. On the other hand, an abundance of released inflammatory cytokines and chemokines causes the profound hyper-inflammation and mobilization of immune cells to trigger a vicious cycle and lead to the cytokine storm. The cytokine storm results in the elevation of cytolytic and cytotoxic molecules and reactive oxygen species (ROS) in the damaged muscle to aggravates the tissue injury, including the healthy bystander tissue. Severe inflammation in the skeletal muscle can lead to rhabdomyolysis and cause sepsis-like systemic inflammation response syndrome (SIRS) and remote organ damage. Therefore, understanding more details on the involvement of inflammatory factors and immune cells in the skeletal muscle damage and repair can provide the new precise therapeutic strategies, including attenuation of the muscle damage and promotion of the muscle repair.
Journal Article